• Journal of Chest Surgery
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• 제10권1호
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• pp.17-24
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• 1977

The present treatment of respiratory failure, using cuffed endotracheal and tracheostomy tube has produced, apparently with increasing frequency, three lesions which have serious ceminical manifestations such as tracheal stenosis, tracheomalasia, and localized tracheal erosion. Extensive resection and reconstruction of the trachea must be necessary because conservative treatment has generally failed in the fully developed stenotic lesion. of the mediastinal trachea following extensive resection is best accomplished by direct anastomosis of the patient`s own tracheobronchial tissue. Any replacement of the mediastinal trachea must be air tight and laterally rigid, and must heal dependably. A variety of materials has been used for substitution following circumferential excision of tracheal segments within the mediastinum. These attempts have often failed because of early leak or late stenosis. We have successfully performed circumferential resection and primary end-to-end anastomosis of the trachea for 4 cases of post-intubation tracheal stenosis located a few centimeter below the tracheostomy stoma in the period of 3 years between 1974 and 1976. The lesion in one patient was found in the upper trachea which was approached anteriorly through a cervicomediastinal incision with division of the upper sternum. Other three located in the lower half of the trachea were operated through a high transthoracic incision with appropriate hilar mobilization in addition to cervical flexion for the development of the cervical trachea into the mediastinum. There were no hospital death, but suture line granulations occurred in two patients were managed by bronchoscopic removal of granulations without difficulties.

• Journal of Chest Surgery
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• 제26권8호
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• pp.664-666
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• 1993

A technique for insertion of a long silicone T-tube in patient with critical stenosis and high-risk resection and primary anastomosis of long segment of the distal trachea is presented. It was not easy to insert a long T-tube by existing methods because of flexibility of a T-tube and tightness of stenosis. So we used a silastic endotracheal tube and guiding wire as stylet of a T-tube. During insertion, ventilation was normally maintained through the lumen of endotracheal tube. This provided rapid relief from airway obstruction and asphyxation and is a easy, safe and effective method to restore patency of the major airways.

• Journal of Chest Surgery
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• 제15권1호
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• pp.73-76
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• 1982

For the treatment of acute respiratory failure and emergency care of an urgent patient, tracheostomy in itself may have been a life saving procedure. But, among the variable complications following tracheostomy, the tracheal stenosis gives serious clinical manifestation which can only be corrected by surgical intervention in many occasions. At the Dept. of thoracic surgery, CAFGH, we have experienced one case of tracheal stenosis following tracheostomy for assisted ventilation. Tracheogram showed a 2.5 cm segmental narrowing 5 cm below the tracheostoma. Before recon-struction, we tried to dilate the stenotic segment for about 2 months, but the result was not satisfactory to relieve dyspnea. So, we resected the narrowed segment and tracheal reconstruction was performed with an excellent result in postoperative periods till now.

• Journal of Chest Surgery
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• 제27권4호
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• pp.324-327
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• 1994

Resection and reconstruction of distal trachea or carina have posed tremendous technical challenges for surgeons. Successful outcome depends on thorough preoperative evaluation, careful anesthetic management,strict attention of surgical technique and postoperative care. We report a successful case of revision of tracheal stenosis using femoro-femoral bypass on a 13~year-old boy. The patient complained severe dyspnea about I month following right sleeve pneumonectomy. Preoperative CT scan and intraoperative bronchoscopy showed pin-point tracheal stenosis at a tracheo-bronchial anastomosis site about 1.2cm in length.At operation the lesion was severely adhesed and the lumen was nearly obstructed. The stenotic segment was resected and direct end-to-end anastomosis was done under femoro-femoral bypass for adequate oxygenation. The patient was discharged at postop. 16 days without specific complications and has continued to do well.

• Journal of Chest Surgery
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• 제21권2호
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• pp.395-402
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• 1988

Increasing success in the management of patients with severe respiratory failure by mechanical respirators has produced iatrogenic tracheal stenosis. And the surgical management of these lesions have provided a major field for tracheal reconstructive surgery. Recently we have experienced three cases of postintubation tracheal stenosis between December, 1985 and October, 1987 and successfully performed circumferential resection and end to end anastomosis of the trachea. The lesion of the first case which was located in the subcricoid level was resected about 2cm length with cervical incision. And the lesion of the second case located at the cuff site was also resected about 2.5cm length with cervical and median sternotomy incision. Also the lesion of the third case located at the stoma site was resected about 1.8cm length with cervical incision. The postoperative courses were uneventful but there was extubation difficulty in the third case because of stupor mentality and problem of secretion excretion. So we have observed the postoperative course after T-tube insertion.

• 대한기관식도과학회지
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• 제1권1호
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• pp.136-141
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• 1995

Tracheostomal stenosis after total laryngectomy is a distressing complication which con-tributes significantly to both psychosocial and physical morbidity according to nature and severity in laryngectomee. Sternal stenosis will compromise not only optimal air exchange, crust formation but also the ability to clear tracheobronchial secretion, so pneumonia and atelectasis will develop. Having a number of procedure recommended for correction of such stenosis with limited results. We developed new technique which is based on tracheal advancement flap had been ap-plied to 12 patients, successfully. We think that total or partial tracheal advancement flap technique Is useful for widening the stoma and advantages of this method are following. 1. Simple technique. possible under local anesthesia 2. Healthy tracheal ring facilities width control 3. Less chance of refractory scar stenosis 4. Tracheoesophageal shunt can be constructed after the partial advancement flap.

• Journal of Chest Surgery
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• 제54권3호
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• pp.191-199
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• 2021

Background: Tracheal replacement is a challenge for thoracic surgeons due to stenosis in the trachea-prosthesis anastomosis. We propose that stenosis occurs due to fibrosis as a result of an abnormal healing process, characterized by an increased expression of wound healing growth factors (vascular endothelial growth factor [VEGF], survivin, and CD31), which promote angiogenesis and decrease apoptosis. We analyzed the immunoreactivity of VEGF, survivin, CD31, and caspase-3 in the development of fibrotic stenosis in prosthetic tracheal replacement. Methods: Fourteen dogs were operated on: group I (n=7) received a 6-ring cervical tracheal segment autograft, while in group II (n=7), a 6-ring segment of the cervical trachea was resected and tracheal continuity was restored with a Dacron prosthesis. The follow-up was 3 months. Immunoreactivity studies for VEGF, survivin, CD31, and caspase-3 were performed. A statistical analysis was done using the Wilcoxon signed rank test. Results: Four animals in group I were euthanized on the 10th postoperative day due to autograft necrosis. Three animals completed the study without anastomotic stenosis. Moderate expression of VEGF (p=0.038), survivin (p=0.038), and CD31 (p=0.038) was found. All group II animals developed stenosis in the trachea-prosthesis anastomotic sites. Microscopy showed abundant collagen and neovascularization vessels. Statistically significant immunoreactive expression of VEGF (p=0.015), survivin (p=0.017), and CD31 (p=0.011) was observed. No expression of caspase-3 was found. Conclusion: We found a strong correlation between fibrosis in trachea-prosthesis anastomoses and excessive angiogenesis, moderate to intense VEGF, CD31, and survivin expression, and null apoptotic activity. These factors led to uncontrolled collagen production.

• Tuberculosis and Respiratory Diseases
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• 제52권1호
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• pp.54-61
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• 2002

배 경 : 동물 모델을 이용하여 일정한 수준의 상기도 협착을 일으킬 수 있다면 이에 대한 임상교육에도 도움이 되며 새로운 진단법이나 치료법의 개발을 보다 쉽게 할 수 있을 것이다. 저자들은 한국산 잡견을 이용하여 Nd-YAG Laser 소작술로 기관 협착을 일정하게 유도하는데 성공하여, 이에 대해 기술하고자 본 연구를 시행하였다. 방 법 : 체중 22kg 정도의 한국산 잡견 6마리를 전신마취 시킨 후, Nd-YAG 레이저를 이용하여 4개의 기관 연골환의 전방부 180도를 $8946{\pm}2484$ Joule로 소작 하였다. 실험 동물은 매 1주마다 4주 동안 기관지내시경으로 기관 협착 정도를 관찰하였고, 병리학적 검사를 같이 시행하였다. 결 과 : 시판 협착은 레이저 소작 2주 후부터 시작되어 3주후까지 빠른 속도로 진행되었으며, 소작 4주 후에 가장 심한 양상을 보였다, 모든 실험 동물은 제 3주가 지나 심한 호흡곤란과 천명음, 식욕부진 및 체중 감소를 보였고, 이중 2마리는 호흡부전으로 4주가 되기 전에 사망하였다. 병리 육안소견상 소작 부위의 기관 연골이 소설되고 섬유조직으로 치환되어 외경도 감소되어 있었고, 현미경 소견에서 연골이 소실되고 섬유화 조직이 협착을 일으켜 내경이 감소된 모습을 확인 할 수 있었다. 결 론 : 이러한 기도 협착 동물 모델은 향후 기도 협착의 이해, 교육, 새로운 진단 및 치료법의 개발에 도움을 줄 것으로 사료된다.

• Journal of Chest Surgery
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• 제24권8호
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• pp.765-772
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• 1991

Between 1985 and 1990, 41 patients underwent treatment of the tracheal stenosis. Nineteen patients underwent resection and end-to-end anastomosis including three cases of the subglottic stenosis. Other patients had had treatment such as LASER therapy, bronchoscopic removal, insertion of the Montgomery silastic T-tube or stent insertion Nineteen patients which underwent resection and end-to-end anastomosis were excellent result from three years to sixth months. Other patient were followed at OPD for the other complication or restenosis. There were no hospital death but one patient was managed by bronchoscopic removal of the granulation tissue and other one patient had underwent reoperation for the dehiscence at the anastomotic site.

• Journal of Chest Surgery
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• 제35권2호
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• pp.149-152
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• 2002

저자들은 이중 기관기관지 스텐트를 성공적으로 거치하여 상당히 긴 부분에 걸쳐 협착이 있는 환아에서 환기유지를 할 수 있었던 증례를 보고한다. 생후 1개월된 환아가 출생 시부터 시작된 빈호흡과 이산화탄소저류를 주소로 응급실로 내원하였다. 술전 흉부단층촬영에서 폐동맥 슬립과 진성성대 직하부부터 양측주기관지 입구에 이르는 상당히 긴 부분에 걸쳐 미만성 기관협착을 확인하였다. 수술소견에서 양측 주기관지의 입구는 3m미만이었으며 기관지협탁부위는 완전환형기관연골이었다. 체외순환 상태에서 좌폐동맥을 잘라 주폐동맥으로 재이식하고 자가심낭편을 이용하여 기관을 확대성형하였다. 그러나, 기관내 육아조직의 성장과 이식한 자가심낭편의 호기시 운동성 폐쇄에 의해 여전히 이산화탄소저류와 호흡곤란은 지속되었다. 이 문제를 해결하기 위해 기관스텐트를 기관내에 거치하였으나, 여전히 양측 주기관지 입구의 협착으로 인해 호흡곤란 증세가 해결되지 않았다. 결국 이중 기관기관지 스텐트를 삽입하여 기도폐쇄를 해결할 수 있었다.