• 대한본초학회지
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• 제37권1호
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• pp.11-18
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• 2022

Objectives : Green gram (mung bean) has a cold nature and has been known to detoxify against various side effects that belong to hot in nature. In particular, since it has the effect of detoxifying fever and detoxification to treat swelling, it was also used externally to treat febrile dermatological diseases such as erysipelas and rubella. This study was designed to determine whether green gram exhibits anti-inflammatory effects on contact dermatitis in mice. Methods : We investigated the effects of green gram extract (70% ethanol extract) on skin lesion, skin thickness and weights, melanin and erythema index and spleen body weight ratio in mice with contact dermatitis induced by repeated application of 1-Fluoro-2,4-dinitrobenzene. Results : Topical application of green gram extract ameliorates skin lesions of contact dermatitis such as scale and roughness induces by 1-Fluoro-2,4-dinitrobenzene. green gram extract also suppressed enlargement of skin thicknesses and weights significantly. In addition, green gram extract treatment also lowered erythema index significantly compared to those in the control group. In the histopathological observation, green gram extract prevented epidermal hyperplasia and hyperkeratosis in inflamed tissues. Finally, green gram extract did not affect changes in body weights and the spleen body weight ratio, unlike dexamethasone, which significantly prevented body weight gain and lowered the spleen body weight ratio. Conclusions : These results imply that green gram, which is known to have a detoxifying effect in Korean medicine, can be used in the treatment of contact dermatitis.

• 대한두개안면성형외과학회지
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• 제23권5호
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• pp.228-231
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• 2022

Fibrin glue is a topical agent widely used for hemostasis, wound healing, and surgical adhesion. Complications of fibrin glue itself are extremely rare because it is absorbed over time, but can occur as a result of inappropriate application. We report a case of a postoperative complication caused by inappropriate application of fibrin glue in blow-out fracture surgery. A 65-year-old male patient presented with periorbital swelling and an open wound on the right infraorbital area. Computed tomography showed a right orbital floor fracture. After reduction of the herniated tissue into the orbit, an implant was inserted and fibrin glue was applied to stabilize the implant. This procedure was performed without difficulty, but the patient complained of persistent diplopia and limited eyeball movement after surgery. An imaging study showed a mass-like lesion, which was not a hematoma, in the orbital cavity. In a second operation, the mass was identified as clotted fibrin glue that had not been applied properly. After removal, the patient's symptoms were relieved without further complications. Appropriate and careful application of fibrin glue is necessary to avoid unnecessary complications.

• 한국심리학회지:법
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• 제13권1호
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• pp.23-52
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• 2022

본 연구에서는 현직 법관 24명을 대상으로 법관들이 재판과 관련하여 사회여론을 어떻게 개념화하는지와 사회여론에 대해 어떤 태도를 취하는지에 대한 초점 집단 면접(FGI)을 실시하고, 인터뷰 내용에 대한 근거이론적 분석과 구조적 토픽 모델링(STM)을 수행하였다. 근거이론적 분석 결과에 따르면, 연구 참여자들은 사회상규, 사회통념, 법감정, 국민정서를 여론과 개념적으로 구분하였고, 여론을 특정한 법적 쟁점이나 사건에 대한 일시적이고 감정적인 반응과 정책에 대한 지속적인 의견으로 구분하여 이해하였다. 그리고 사건의 종류나 법적 쟁점에 따라 여론이나 사회통념에 대해 다른 태도를 취하는 것으로 나타났다. 토픽 모델링 결과는 근거이론적 분석 결과와 상당한 유사성을 보였고, 특정 토픽의 발현 가능성은 연구 참여자들의 담당 사건 종류에 따라 통계적으로 유의미한 차이를 보였다.

• 대한본초학회지
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• 제28권6호
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• pp.25-29
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• 2013

Objectives : The dried root of Sophora flavescens Aiton have been used to treat patient with skin diseases such as eczema in Eastern countries. S. flavescens can clear away heat and dry dampness and purge sthenic-fire from the liver and gallbladder. Recently, anti-allergic effect of S. flavescens has been reported. However, the effect on skin condition of contact dermatitis still remains unknown. Thus, the purpose of this study is to evaluate the efficacy of S. flavescens on contact dermatitis. Methods : In order to investigate the effects of S. flavescens (methanol extract of S. flavescens, MESR) on skin condition, the contact dermatitis was induced in mice skin by using 1-fluoro-2,4-dinitrofluorobenzene (DNFB). As the effective endpoints, skin thickness, skin weight, histopathological change were checked. In addition, effects on skin lesion, body weight and spleen/body weight ratio were also investigated. Results : Topical application of MESR ($500{\mu}g/day$) lowered skin thickness (P < 0.05) and skin weight (P < 0.05), respectively. MESR-treated group showed diminished spongiosis and immune cell infiltration in skin tissues compared to those of non-treated control group. The inhibition of skin lesions was also observed in MESR-treated group. In addition, MESR did not affect body weight gain and spleen/body weight ratio in contrast with those in dexamethasone-treated group. Conclusion : These data suggest that Sophorae Radix could improve skin lesion of contact dermatitis. This indicates the possibility for Sophorae Radix to be used to patients with skin diseases such as contact dermatitis.

• Clinics in Shoulder and Elbow
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• 제26권1호
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• pp.25-31
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• 2023

Background: This study analyzed questions searched by rotator cuff patients and determined types and quality of websites providing information. Methods: Three strings related to rotator cuff repair were explored by Google Search. Result pages were collected under the "People also ask" function for frequent questions and associated webpages. Questions were categorized using Rothwell classification and topical subcategorization. Webpages were evaluated by Journal of the American Medical Association (JAMA) benchmark criteria for source quality. Results: One hundred twenty "People also ask" questions were collected with associated webpages. Using the Rothwell classification of questions, queries were organized into fact (41.7%), value (31.7%), and policy (26.7%). The most common webpage categories were academic (28.3%) and medical practice (27.5%). The most common question subcategories were timeline of recovery (21.7%), indications/management (21.7%), and pain (18.3%). Average JAMA score for all 120 webpages was 1.50. Journal articles had the highest average JAMA score (3.77), while commercial websites had the lowest JAMA score (0.91). The most commonly suggested question for rotator cuff repair/surgery was, "Is rotator cuff surgery worth having?," while the most commonly suggested question for rotator cuff repair pain was, "What happens if a rotator cuff is not repaired?" Conclusions: The most commonly asked questions pertaining to rotator cuff repair evaluate management options and relate to timeline of recovery and pain management. Most information is provided by medical practice, academic, and medical information websites, which have highly variable reliability. By understanding questions their patients search online, surgeons can tailor preoperative education to patient concerns and improve postoperative outcomes.

• 대한두개안면성형외과학회지
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• 제24권1호
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• pp.10-17
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• 2023

Background: Lipomas are common benign tumors of mesenchymal origin that are composed of mature adipocytes. Giant lipomas have a diameter ≥ 10 cm in one or more dimensions or weigh at least 1,000 g. The surgical excision of a giant lipoma requires extensive dissection, increasing the risk of a seroma, which can cause surgical site complications such as wound infection and necrosis. Sclerotherapy with Abnobaviscum (Viscum album extract) is a relatively new technique used to reduce malignant pleural effusion. In this study, we evaluated the effectiveness of prophylactic sclerotherapy using Abnobaviscum to decrease seroma after giant lipoma excision. Methods: We conducted a retrospective medical record review of patients who underwent surgical excision for giant lipoma of the neck from January 2019 to December 2022. Sclerotherapy was performed on the first postoperative day in patients who consented to the procedure, and Abnobaviscum was instilled through the existing Hemovac drain. We compared the clinical course between those who underwent postoperative sclerotherapy and those who did not. Results: Among the 30 patients who underwent giant lipoma excision, we applied sclerotherapy with Abnobaviscum to 15 patients. The average time from surgery to Hemovac removal was statistically shorter in patients who underwent sclerotherapy (p= 0.004). Furthermore, seroma formation was significantly reduced in patients receiving sclerotherapy (p= 0.003). Conclusion: In patients undergoing giant lipoma excision, sclerotherapy using Abnobaviscum helps reduce postoperative seroma formation during the initial postoperative period. It can be an excellent method to reduce complications related to seroma and attenuate patients' postoperative burden.

• 무역학회지
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• 제45권5호
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• pp.239-260
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• 2020

This research was conducted on 176 GVCs-related research papers listed in the Index of Korean Academic Writers. The analysis methodology used the keyword network analysis methodology of big data analysis. For the comprehensive analysis of research trends, the research trends through word frequency (TF), important topic (TF-IDF), and topical modeling were analyzed in 176 papers. In addition, the research period of GVCs was divided into the early stages of the first study (2003-2014), the second phase of the study (2015-2017), and the third phase of the study (2018-2020). According to the comprehensive analysis, the GVCs research was conducted with the keyword 'value added' as the center, focusing on the keywords of export (trade), Korea, business, influence, and production. Major research topics were 'supporting corporate cooperation and capacity building' and 'comparative advantage with added value of overseas direct investment'. According to the analysis of major period-specific research trends, GVCs were studied in the early stages of the first phase of the study with global value chain trends and corporate production strategies. In the second research propulsion period, research was done in terms of trade value added. In the recent third phase of the study, small and medium-sized enterprises actively participated in the global value chain and actively researched ways to support the government. Through this study, the importance of the global value chain has been confirmed quantitatively and qualitatively, and it is recognized as an important factor to be considered in the strategy of enhancing industrial competitiveness and entering overseas markets. In particular, small and medium-sized companies' participation in the global value chain and support measures are being presented as important research topics in the future.

• 대한정형외과학회지
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• 제56권5호
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• pp.391-397
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• 2021

목적: 트라넥삼산(tranexamic acid, TXA)은 하지 수술에서 출혈과 수혈 빈도를 줄이는 것으로 알려졌다. 본 연구에서는 역행성 견관절 전치환술 시에 출혈 및 수혈 요구에 대한 TXA의 효과를 평가하고자 하였다. 대상 및 방법: 2009년 9월부터 2020년 7월까지 역행성 견관절 전치환술을 시행한 환자를 평가하였다. 수술 중 정맥로와 관절강 내 도포를 시행한 군은 TXA 사용군, 시행하지 않은 군은 TXA 미사용군으로 분류하였다. 술 후 출혈량을 나타내는 배액관 배액량과 수혈 여부, 술 후 혈색소와 적혈구 용적률 수치를 분석하였다. 결과: TXA 사용군과 TXA 미사용군 간 연령(72.0±7.0 vs. 71.5±5.8, p=0.656) 및 남, 녀 성별 비율(28:65 vs. 23:61, p=0.689)은 유의한 차이가 없었다. 또한 고혈압, 당뇨병, 두 질환 모두를 가진 환자의 유병률(36:3:13 vs. 32:3:8, p=0.806)은 양 군 간 유의한 차이가 없었다. 수혈 기준에 따라 수혈을 시행한 수혈 환자 수(0 vs. 9, p=0.001)는 TXA 사용군에서 없었으며 TXA 미사용군에서 유의하게 더 많았다. 수술 1일째(98.8±61.2 ml vs. 162.7±98.8 ml, p<0.001) 및 제거 당시 배액관 배액량(73.8±48.4 ml vs. 91.5±54.5 ml, p=0.024)은 둘 다 TXA 사용군에서 유의하게 더 적었다. 수술 전 측정한 혈색소 수치(13.2±1.4 vs. 13.3±1.5, p=0.374)와 적혈구 용적률 수치(39.5±3.9 vs. 39.6±4.7, p=0.946)에서 양 군 간 유의한 차이가 없었다. 수술 1일째(11.7±1.2 g/dl vs. 11.2±1.4 g/dl, p=0.048), 3일째(10.9±1.2 g/dl vs. 10.2±1.2 g/dl, p<0.001), 6일째 혈색소(11.2±1.3 g/dl vs. 10.7±1.3 g/dl, p=0.020)는 TXA 사용군에서 유의하게 높았다. 수술 1일째(35.0%±3.6% vs. 32.5%±3.8%, p=0.001), 3일째(32.3% ±5.0% vs. 29.8%±3.6%, p<0.001), 6일째 적혈구 용적률 수치(33.5%±3.8% vs. 31.5%±3.7%, p<0.001)에서도 TXA 사용군에서 유의하게 높았다. 결론: 역행성 견관절 전치환술 시행 시 정맥로와 관절강 내 국소도포를 이용한 TXA의 사용은 수술 후 수혈의 필요성과 출혈량을 줄일 수 있다.

• 한국콘텐츠학회논문지
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• 제20권11호
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• pp.28-37
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• 2020

본 연구는 '수돗물 유충' 사태의 뉴스 빅데이터를 분석함으로써, '수돗물 유충'과 관련된 주요 키워드와 토픽을 파악하여, 환경문제에 대한 위기 대응력 제고방안을 제안하기 위해 수행되었다. 2020년 7월 13일부터 8월 31일까지 보도된 1,975건의 '수돗물 유충' 뉴스를 토픽 모델링 기법으로 분석하였다. 그 결과 언론에서 나타난 '수돗물 유충' 사태가 발생기, 확산기, 수습기로 구분되며, 각 5개의 토픽을 선정하여, 환경문제의 발생과 추진 과정을 확인할 수 있었다. 분석 결과를 바탕으로 환경문제에 대한 위기 대응 방안을 다음과 같이 제언하였다. 첫째, '수돗물 유충' 사건을 중심으로 얽혀있는 다양한 맥락을 탐구하고 통합적인 안목을 형성하는 교육으로 환경문제에 대한 대응력을 기를 수 있도록 해야 한다. 둘째, 인터넷 커뮤니티를 활용한 시민참여의 환경정보 공유와 환경감시 역할 부여가 필요하다. 셋째, 신속하고 정확한 환경정보 제공과 소통을 담당하는 환경 커뮤니케이터의 양성 및 배치가 필요하다. 본 연구는 '수돗물 유충' 관련 뉴스 빅데이터를 기반으로 국내에서 처음으로 토픽 모델링 분석기법을 활용하여 분석한 연구로서, 비정형 데이터로 나타나는 환경 관련 이슈를 실증적이고 체계적으로 분석했다는 학술적 의의와 환경교육 및 커뮤니케이션 개선 방안을 제시했다는 정책적 의의를 지닌다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권5호
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• pp.468-473
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• 2001

본 교실에서는 우측 악하부와 우측 안와 하부의 종창으로 내원한 53세 여자 환자에서 Fine Needle Aspiration Biopsy로 림프절의 반응성 과증식으로 진단되어 다시 절제 생검을 시행하여 multi-centric Castleman's disease로 진단하였다. 조직 검사상 유리질 혈관형과 형질세포형이 공존하는 복합형으로 나타났으며 병소의 적출술만을 시행한 후 1년이 지난 지금까지는 별다른 소견없이 좋은 경과를 나타내고 있으며 앞으로도 계속 주의깊은 관찰이 필요로 한다.