• Proceedings of the Korea Inteligent Information System Society Conference
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• 2001.01a
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• pp.211-218
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• 2001

This paper introduces a method of constructing expert systems in an integrated environment for automatic software design. This integrated environment may be applicable from top-level system architecture design, data flow diagram design down to flow chart and coding. The system is integrated with three CASE tools, FSD (Functional Structure Diagram), DFD (Data Flow Diagram) and structured chart PAD (Problem Analysis Diagram), and respective expert systems with automatic design capability by reusing past design. The construction way of these expert systems is based on systematic acquisition of design knowledge stemmed from a systematic design work process of well-matured developers. The design knowledge is automatically acquired from respective documents and stored in the respective knowledge bases. By reusing it, a similar software system may be designed automatically. In order to develop these expert systems in a short period, these design knowledge is expressed by the unified frame structure, functions of th expert system units are partitioned mono-functions and then standardized components. As a result, the design cost of an expert system can be reduced to standard work procedures. Another feature of this paper is to introduce the integrated environment for automatic software design. This system features an essentially zero start-up cost for automatic design resulting in substantial saving of design man-hours in the resulting in substantial saving of design man-hours in the design life cycle, and the expected increase in software productivity after enough design experiences are accumulated.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2017.05a
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• pp.3-23
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• 2017

The achievement of tissue engineering can be highly depending on the capability to generate complicated, cell seeded three dimensional (3D) micro/nano-structures. So, various fabrication techniques that can be used to precisely design the architecture and topography of scaffolding materials will signify a key aspect of multi-functional tissue engineering. Previous methods for obtaining scaffolds based on top-down are often not satisfactory to produce complex micro/nano-structures due to the lack of control on scaffold architecture, porosity, and cellular interactions. However, a bioprinting method can be used to design sophisticated 3D tissue scaffolds that can be engineered to mimic the tissue architecture using computer aided approach. Also, in recent, the method has been modified and optimized to fabricate scaffolds using various natural biopolymers (collagen, alginate, and chitosan etc.). Variation of the topological structure and polymer concentration allowed tailoring the physical and biological properties of the scaffolds. In this presentation, the 3D bioprinting supplemented with a newly designed plasma treatment for attaining highly bioactive and functional scaffolds for tissue engineering applications will be introduced. Moreover, various in vivo and in vitro results will show that the fabricated scaffolds can carry out their structural and biological functionality.

• Journal of The Korean Association For Science Education
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• v.29 no.7
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• pp.751-758
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• 2009

The purpose of this study was to investigate brain activation pattern and functional connectivity network during classification on the biological phenomena. Twenty six right-handed healthy science teachers volunteered to be in the present study. To investigate participants' brain activities during the tasks, 3.0T fMRI system with the block experimental-design was used to measure BOLD signals of their brain. According to the analyzed data, superior, middle and inferior frontal gyrus, superior and inferior parietal lobule, fusiform gyrus, lingual gyrus, and bilateral cerebellum were significantly activated during participants' carrying-out classification. The network model was consisting of six nodes (ROIs) and its fourteen connections. These results suggested the notion that the activation and connections of these regions mean that classification is consist of two sub-network systems (top-down and bottom-up related) and it functioning reciprocally. These results enable the examination of the scientific classification process from the cognitive neuroscience perspective, and may be used as basic materials for developing a teaching-learning program for scientific classification such as brain-based science education curriculum in the science classrooms.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.622-627
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• 2009

Business process engineering (BPE) is a top-down management approach for increasing efficiency and productivity through radical and fundamental changes to the business processes of the organization. BPE requires firms to initially develop a model of the existing business processes of the firm to distinguish functional tasks from processes used for coordinating inputs, activities and outputs. The model is used for understanding the business processes in the organization and to simulate the effect of changes to the processes. The model can also be used to justify business processes, which involves assessing whether the business process provides value to the customer in its current configuration. Justification requires a careful examination of the key business processes used by the firm to identify systemic shortcomings in the process and to create a new business process to produce greater efficiency. BPE also considers automating as many business processes as possible to increase operational efficiency and the integration of business process tasks. The construction industry has been slow to adopt BPE because of its project approach in which a major firm contracts with various functional service providers and regards each project as unique. The industry focuses on functional task efficiency rather than business process efficiency. There is no formal methodology or criteria for determining whether a business process is effective for a construction firm in its current configuration. The use of performance measures such as costs, task duration times or other metrics can be useful in evaluating the effectiveness of an existing business process and for modeling the possible outcome of a fundamental and radical change to the process.

• Proceedings of the IEEK Conference
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• 1999.06a
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• pp.345-348
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• 1999

본 논문에서는 내장형 응용에 적합한 RISC 마이크로프로세서와 DSP 프로세서의 기능을 유기적으로 결합한 구조를 연구하고 이를 설계한다. 프로그램의 크기를 줄이기 위해 RISC 명령어는 16비트 명령어 집합을 설계하고 분기 명령어로 인한 손실을 줄이기 위해 한 개의 지연 슬롯을 갖고 있다. DSP 명령어는 32비트 길이를 갖고 한 명령어로 곱셈, 덧셈(뺄셈), 두 가지 데이터 이동을 할 수 있어서 한 사이클에 최대 네 가지 동작을 할 수 있다 파이프라인 단계는 IF, ID, EX, MA, WB/DSP의 다섯 단계로 구성된다. DSP 기능을 지원하기 위해 내부 루프 버퍼를 갖고 정수 실행부에서는 주소 발생을 위한 전용 하드웨어와 DSP 유닛에서는 곱셈 및 누적 기능을 지원하기 위한 17 × 17 비트 곱셈기가 내장된다. 제안된 구조의 설계는 Verilog-HDL을 이용하여 top-down 설계 방식으로 설계되었고 각 기능 검증을 마친 후 3.3V, 0.6㎛ CMOS triple metal single poly 공정을 이용하여 합성하고 레이아웃 하였다.

• Korean Journal of Biological Psychiatry
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• v.28 no.2
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• pp.36-49
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• 2021

Suicide is a leading cause of death worldwide, especially among adolescents and young adults. Considering this fact, it is imperative that we understand the neural mechanisms underlying suicidal thoughts and behaviors in youth from a neurodevelopmental perspective. In this review, we focused on the magnetic resonance imaging studies that examined the neural correlates of suicidal ideations (SI) or attempts (SA) in youth. We reviewed twenty-three cross-sectional studies reporting the structural and functional alterations in association with SI or SA among adolescents and young adults with various mental disorders. The previous literature suggests that the dorsolateral prefrontal cortex, anterior cingulate cortex, and ventral frontolimbic circuit, may play an important role in the pathophysiology of suicidal behavior in youth through altered top-down control over emotion and impulsivity. Future studies with a longitudinal design and using multimodal imaging techniques may be of help to identify novel therapeutic targets specific for youth with suicidal thoughts and behaviors.

• Journal of Dental Rehabilitation and Applied Science
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• v.38 no.4
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• pp.249-256
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• 2022

The implant prosthesis of anterior maxilla requires careful consideration in planning. In order to satisfy both esthetic and functional needs of a patient, fusion of intra-oral scan in Cone-beam computed tomography (CBCT) and facial scan can be considered. Bony structures and soft tissues captured in CBCT and occlusal surfaces of intra oral scan were incorporated into personal characteristics from facial scan. The patient had insufficient buccal bone on maxillary anterior area. The maxillary implants could not be placed on the most ideal position. However, the "top down" approach completed by computer-generated arranging of teeth in implant planning and surgery with surgical guide resulted in esthetically and functionally satisfying result regardless of the limitation. Careful diagnosis with digital technique and the usage of surgical guide resulted in successful surgery and esthetic restoration. The temporary fixed prostheses were designed, restored and evaluated. The patient was not satisfied with the first design of temporary prosthesis, which showed uneven space distribution between teeth due to the position of maxillary implant. The design was modified by changing proximal emergence contours and line angle to alter the perceived since of incisors. The patient was satisfied with the new design of provisional restoration. A digital occlusion analyzer (Arcus Digma II, KaVo, Leutkirch, Germany) was used to measure inherent condylar guidance and anterior guidance of a patient to provide a definitive prosthesis.