• Journal of Environmental Health Sciences
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• v.43 no.5
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• pp.401-411
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• 2017

Objectives: The purpose of this study was to investigate the factors affecting the use of oral hygiene products in infants. Methods: From October 2015 to December 2015, astructured questionnaire survey was conducted for infants and parents about the infants' oral hygiene product use from 0 to 4 years of age in Seoul and other metropolitan areas. Results: The use of oral tissues for infants and children was more frequent in infants, with less than four uses of oral tissues per 10 infants. The overall amount of toothpaste usage among infants was lower than those of infants whose parents are high school or college graduates. The number of oral tissues used per infant per week was less among infants who sucked less than 4 times per 10 infants. The frequency of use of infant mouthwash per week in every 10 infants was less than those who swallow mouthwash less than once. The number of mouth rinses after the use of oral tissues for infants was high in boys, and the number of infants who sucked oral tissues was less than 4 times when used 10 times. The number of mouth rinses after the use of toothpaste was less for infants with college-graduate parents. The factors affecting the number of mouth rinsings after using oral tissues for infants were gender and sucking frequency. Conclusions: In this study, the oral hygiene products for infants were found to differ and affect the usage, the frequency of use, and the number of mouth rinses according to the general characteristics of infants' and parents and the use of oral hygiene products.

• Journal of dental hygiene science
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• v.6 no.2
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• pp.93-99
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• 2006

This study was carried out to investigate practical application status of oral hygiene devices through making a survey of labor of the D industrial company-about carefully curing oral disease in home, the status of practical application of tooth brush, the status of practical application of fluoridated toothpaste, status of practical application of auxiliary oral hygiene devices, a motive use or unuse of auxiliary oral hygiene devices. 1. In home, carefully curing oral disease is dental caries(62.4%). 2. Status of practical application toothbrush showed the highest user ratio of mideum size(79.6%). 3. Showed the highest user ratio of horizontal plane toothbrush(73.5%). 4. Answerd don't take a prudent attitued in choice of fluoridated toothpaste(73.5%). 5. In the status of reconition of oral hygiene devices, showed the highest user ratio of eletric toothbrush(77.0%). 6. In the status of reconition of auxiliary oral hygiene devices, showed the highest user ratio of wooden wedge stimulator(89.4%)and gargle liquid(84.5%). In using of oral hygiene devices, showed the highest user ratio of electric toothbrush(13.3%), toohbrush for periodontal patients(2.7%). In using of auxiliary, wooden wedge stimulator (58.4%)and gargle liquid(41.2%). In effect using of oral hygiene devices showed the highest user ratio of denture brush(50.0%)and eletric toothbrush(43.3%), in effect using of auxiliary oral hygiene devices showed the highest user ratio of water pick(80.0%) and dental floss(75.8%). 6. A motive of the use auxiliary oral hygiene device is choice by oneself through TV, advertisement, public information(57.6%), and the reason-they don't use of auxiliary oral hygiene devicebecause of they don't know proper to them the kind of auxiliary oral hygiene device.

• Journal of Oral Medicine and Pain
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• v.21 no.1
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• pp.133-140
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• 1996

Saliva have many important functions in the maintenance of oral health. Saliva contains protective components, antibacterial enzymes, and other rubricating glycoprotein elements. When the salivary flow decreases of the salivary composition changes, a normally healthy mouth can become susceptible to caries, periodontal disease, and mucositis, and other diseases. Salivary peroxidase system acts as an antimicrobial factor in the oral cavity, having a role in the prevention of dental plaque accumulation, dental caries and gingivitis. Recently, this enzyme system has been introduced by many researchers in the form of toothpaste, mouthwash or moisturizing gel for use in patients with various disease states . The author prescribed the peroxidase system containing gel (Oralbalance) to the 18 Burning Mouth Syndrome (BMS) patients for 1 week and investigated the changes of the subjective symptoms, $HOSCN/OSCN^-$ levels of unstimulated whole saliva, and the salivary flow rates. The obtained results were as follows : 1. The patients reported decrease in all symptoms of BMS after the use of peroxidase system containing gel, particulary, a significantly higher decreases of dry mouth and burning symptoms. 2. Decreased $HOSCN/OSCN^-$ levels of unstimulated whole saliva were detected in the patients with BMS after the use of perosidase system containing gel for 1 week. 3. There was no difference between the flow rates of unstimulated whole saliva before and after uses of peroxidase system containing gel for 1 week.

• Journal of Microbiology and Biotechnology
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• v.26 no.9
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• pp.1579-1585
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• 2016

Sugar esters are valuable compounds composed of various sugars and fatty acids that can be used as antibacterial agents and emulsifiers in toothpaste and canned foods. For example, fructose fatty acid esters suppress growth of Streptococcus mutans, a typical pathogenic bacterium causing dental caries. In this study, fructose laurate ester was chosen as a target material and was synthesized by a transesterification reaction using Candida antarctica lipase B. We performed a solvent screening experiment and found that a t-butanol/dimethyl sulfoxide mixture was the best solvent to dissolve fructose and methyl laurate. Fructose laurate was synthesized by transesterification of fructose (100 mM) with methyl laurate (30 mM) in t-butanol containing 20% dimethyl sulfoxide. The conversion yield was about 90%, which was calculated based on the quantity of methyl laurate using high-performance liquid chromatography. Fructose monolaurate (M_r 361) was detected in the reaction mixture by high-resolution mass spectrometry. The inhibitory effect of fructose laurate on growth of oral or food spoilage microorganisms, including S. mutans, Bacillus coagulans, and Geobacillus stearothermophilus, was evaluated.

• Journal of Microbiology and Biotechnology
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• v.12 no.1
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• pp.18-24
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• 2002

The present study was performed to investigate the excellent microbial anticaries substance, aminoglycoside antibiotic, which is more effective than chlorhexidine for the treatment of dental caries. The aminoglycoside antibiotic against Streptococcus mutans JC-2 from a novel alkaliphilic Bacillus alkalophilshaggy JY-827 exhibited no significant difference at the treatment concentration of $2.5{\times}10^{-7}M$, however, it inhibited the activity of the Streptococcus mutans glucosyltransferase by 70.2% and 99.8% at the concentrations of $2.5{\times}10^{-7}$M\;and\;2.5{\times}10^{-6}M$, respectively. Lineweaver-Burk plot of the inhibitory aminoglycoside antibiotic showed competitive inhibition, with $K_i$ value of $6.4{\times}10^{-6}$ M. The aminoglycoside antibiotic did not show any cytotoxicity against human gingival cells. To evaluate the industrial applicability of the aminoglycoside antibiotic, a toothpaste containing this substance was prepared and tested on the extracted human teeth. The inhibitory rate of tooth calcification and calcium ion elution by the aminoglycoside antibiotic were 50% and 2.5 times, respectively. These results suggested that the aminoglycoside antibiotic from Bacillus alkalophilshaggy JY-827 is an effective agent against dental caries.

• Journal of Korean society of Dental Hygiene
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• v.15 no.5
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• pp.813-821
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• 2015

Objectives: The purpose of the study was to investigate the relationship between health behavior and oral symptoms in Korean adolescents. Methods: The subjects were 72,060 adolescents who were selected from the web-based survey of the 10th (2014) Korean Youth Risk Behavior of Korean Center for Disease Control. Data were analyzed by PASW statistics 18.0. A web-based self-reported questionnaire was completed by 74,167 middle and high school students. The subjects consisted of 36,470 boy students (52.2%) and 35,590 girl students (47.8%) from 400 middle schools and 400 high schools. Results: Multiple logistic regression analysis revealed that experience of oral symptoms were related with sex, age, academic achievement, economic status, alcohol drinking, moderate physical activity, muscular strength exercises, walking, fruit consumption, milk consumption, fast food consumption, snack consumption, daily tooth brushing frequency, use of fluoride toothpaste, school based oral health education, dental sealant and dental scaling. Conclusions: There were close relationship between heath behavior, oral health behavior, and experience of oral symptoms. To improve the health promotion for the adolescents, oral health program development and primary prevention strategy must be established.

• International Journal of Oral Biology
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• v.43 no.3
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• pp.123-127
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• 2018

Polyphenon 60 refers to the mixture of catechins present in green tea. The aim of this study was to investigate the antimicrobial activities of polyphenon 60 against 4 strains of Streptococcus mutans and 2 strains of Streptococcus sorbrinus, which are the major causative bacteria of dental caries. The minimum bactericidal concentration (MBC) values of polyphenon 60 for S. mutans and S. sobrinus were determined and the effect of biofilm formation inhibition of that was evaluated. The MBC value of polyphenon 60 against the bacterial strains was 2.5 mg/ml except for one particular strain, S. mutans KCOM 1128 for which the value was 1.25 mg/ml. The results of biofilm formation inhibition assay revealed that polyphenon 60 inhibited biofilm formation more than 90% at a concentration of 2.5 mg/ml. It was apparent that polyphenon exhibited biofilm formation inhibition activity along with bactericidal effect against S. mutans and S. sobrinus. Therefore, it is proposed that polyphenon 60 as one of the components of bactericidal agents could be useful in developing oral hygiene products, toothpaste or gargling solution.

• Journal of Korean society of Dental Hygiene
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• v.21 no.2
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• pp.99-107
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• 2021

Objectives: To compare and evaluate the degree of abrasion of the denture base resin according to the type of denture cleansers. Methods: Denture base resin specimens were prepared and dried. The resin specimens were installed in the automatic brushing machine so that the toothbrush weighed 200 g. The brushing was performed 1,000 times each, a total of 10,000 times using (1) distilled water (DW), (2) non-abrasive cleanser (NAC), and (3) toothpaste (TP), respectively. Thirty specimens were allocated for each group. The thickness of abrasion by brushing was calculated by converting the weight of the specimen. Results: In all DW, NAC, and TP groups, significant differences were found in the average amount of abrasion of the resin specimen due to 1,000 to 10,000 brushings (p<0.001). The average abrasion amount of the resin specimen due to brushing 10,000 times was 2.31±1.20 ㎛ in DW group, 2.52±0.25 ㎛ in NAC group, 6.50±0.60 ㎛ in TP group, and the amount of abrasion in the TP group was statistically significant compared to other groups (p<0.001). Conclusions: The use of TP is not recommended as a method for maintaining the longevity of dentures and for oral health, and NAC was considered to be possible to be used as a denture cleanser because it had a similar amount of abrasion of that of DW.

• Journal of Oral Medicine and Pain
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• v.21 no.1
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• pp.141-152
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• 1996

Oral Lichen Planus(OLP) is a idiopathic chronic inflammatory disease with more difficult to clear and higher recurrent rate than cutaneous lesions. But, there has been no estabilished theories about the proper treatment for OLP. The purpose of this study is to examine the clinical feature, relationship with systemic disease and dental treatment of OLP patients of Korea and to gain helpful information about clinical characteristics and treatment of OLP. The subjects chosen for the study were 54 patients who had visited Department of Oral Diagnosis & Oral Medicine at Yonsei University Dental Hospital Dental Hospital and diagnosed as OLP. Previous clinical records has been reviewed and questionnaires, oral examination, laboratory examination were done and recorded. The following results were obtained : 1. Of the 54 patients, 21 were men and 33 were women with an average age of 47.8 years. 2. The most common intraoral site was bilateral buccal mucosa, followed by unilateral buccal mucosa, gingiva, vesibule, lip mucosa, glossal mucosa, palatal mucosa and mouth floor. 3. The mixed, erosive and reticular form of OLP was most frequent(83.3%) clinical form. 4. OLP patients with liver disease were 5, and drug medication patients were 7. But, we could not find its evidence of association with OLP. 5. Associated events on onset of symptom were stress, denture wearing, dental treatemtn, and common cold. 6. Associated symptoms were dry mouth, tingling, sore throat, and altered taste perception. 30.8% of patients had no specific associated symptoms. 7. Aggravating factors of symptom were peppery food, hot food, fatigue, toothpaste, salty food, sour food, tension, and conversation. Reducing factors were cold food, sleeping. 69.2% of patients had no specific reducing factors. 8. There were no significant differences between normal papulation and OLP patients in CBC, SGOT< SGPT, Serum iron, Total iron binding capacity. 66.7% of subjects were positive response to fungus study for Candida Albicans. The incidence of stress and dental treatment on onset of symptom appeared high in OLP patients. Especially, high incidence of positive response to fungus study for Candida albicans, prescription of anti-fungal agents and dental treatment considerations may be helpful to treatment of OLP.

• The Journal of Korean Society for School & Community Health Education
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• v.11 no.1
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• pp.27-39
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• 2010

Objectives: This study was conducted to find out caries preventive effect on permanent teeth among children who brush teeth with fluoride-containing toothpaste by supervised weekly fluoride mouthrinsing program in elementary schools. Methods: The epidemiologic dental survey was performed on the elementary schoolchildren of supervised weekly fluoride mouthrinsing program (FMR) with 0.2 percent neutral sodium fluoride solution and control group in 2007. Caries preventive effect on permanent teeth by fluoride mouthrinsing program were calculated by DMFT index and DMFS index between FMR group and control group. Results: By DMFT index between FMR group and control group, caries rates on permanent teeth of the fourth-, fifth- and sixth-grade children participating in FMR program were 34.1%, 40.8% and 31.5%, respectively. By the DMFS index between FMR group and control group, caries preventive rates on permanent teeth of the fourth-, fifth- and sixth-grade children participating in FMR program were calculated 25.4%, 37.7% and 33.5%, respectively. Conclusions: We suggest that fluoride mouthrinsing program should be developed to all elementary schools to prevent dental caries.