• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.1-11
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• 1996

From the concepts of cellular pathology and of exfoliative cytology, as elucidated by Virchow and Papanicolaou respectively in the late 19th and early 20th century, have evolved the primary methods for the diagnosis of cancer today. From Papanicolaou's concept of exfoliative cytology developed fine needle aspiration biopsy in the early 1960's, this has become a major diagnostic procedure and has contributed to a significant reduction in open biopsies and, therefore, to medical cost-effectiveness immunobiochemical techniques provided us with a supplement to cancer diagnosis in the 1980's. The immunoperoxidase method, using monoclonal antibodies, is applied primarily as an ancillary measure to elucidate the nature of cancers The availability of specific monoclonal antibodies has greatly facilitated the identification of cell products or surface markers. For example, antibodies directed against intermediate filaments have proved to be of value in determining the histogenesis oi poorly differentiated neoplasms. Tumor markers may serve as biochemical indicators of the presence of a neoplasm. They can be detected In plasma and other body fluids. Their concentration can be applied as a diagnostic test, for monitoring the clinical course of known cancer, and as a screening measure to detect certain cancers in a population at risk. Flow cytometry is a useful tool for distinguishing several cell characteristics, such as the immunophenotype of leukemia-lymphoma cells, the DNA content of neoplastic cells, and cell proliferation rate. Molecular biologic techniques provided a giant step for the management of cancer patients encompassing diagnosis, prognostic evaluation, and therapy. Nucleic acid hybridization techniques are utilized as Southern, Northern, and dot blots and in situ hybridization. Molecular biology and its techniques may bring a blight new horizon for understanding cancer biology and in designing therapy on the basis of gene manipulation.

• Asian Journal of Atmospheric Environment
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• v.12 no.3
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• pp.232-243
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• 2018

The construction, development and maintenance of an economically, environmentally and socially sustainable campus involves the integration of measuring tools and technical information that invites and encourages the community to know the actual state to generate positive actions for reducing the negative impacts over the local environment. At the Universidad Nacional de Colombia - Campus $Bogot{\acute{a}}$, a public area with daily traffic of more than 25000 people, the Environmental Management Bureau has committed with the monitoring of the noise pollution and air quality, as support to the campaigns aiming to reduce the pollutant emissions associated to the student's activities and campus operation. The target of this study is based in the implementation of mobile air quality and sonometry monitoring equipment, the mapping of the actual air quality and noise pollution inside the university campus as a novel methodology for a sub-area inside a megacity. This results and mapping are proposed as planning tool for the institution administrative sections. A mobile Kunak$^{(R)}$ Air & OPC air monitoring station with the capability to measure particulate matter $PM_{10}$, $PM_{2.5}$, Ozone ($O_3$), Sulfur Oxide ($SO_2$), Carbon Monoxide (CO) and Nitrogen Oxide ($NO_2$) as well as Temperature, Relative Humidity and Latitude and Longitude coordinates for the data georeferenciation; and a sonometer Cirrus$^{(R)}$ 162B Class 2 were used to perform the measurements. The measurements took place in conditions of academic activity and without it, with the aim of identify the impacts generated by the campus operation. Using the free code geographical information software QGIS$^{(R)}$ 2.18, the maps of each variable measured were developed, and the impacts generated by the operation of the campus were identified qualitative and quantitively. For the measured variables, an increase of around 21% for the $L_{Aeq}$ noise level and around 80% to 90% for air pollution were detected during the operation period.

• Journal of the Korean association of regional geographers
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• v.18 no.4
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• pp.473-493
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• 2012

Malaria infection is sensitively influenced by regional meteorological conditions along with global climate change. Remote sensing techniques have become an important tool for extraction of climatic and environmental factors, including rainfall, temperature, surface water, soil moisture, and land use, which are directly linked to the habitat qualities of malaria mosquitoes. Improvement of sensor fidelity with higher spatial and spectral resolution, new multinational sensor development, and decreased data cost have nurtured diverse remote sensing applications in malaria research. In 1984, eradication of endemic malaria was declared in Korea, but reemergence of malaria was reported in mid-1990s. Considering constant changes in malaria cases since 2000, the epidemiological management of the disease needs careful monitoring. Geographically, northmost counties neighboring North Korea have been ranked high in the number of malaria cases. High infection rates in these areas drew special attention and led to a hypothesis that malaria dispersion in these border counties might be caused by north-origin, malaria-bearing adult mosquitoes. Habitat conditions of malaria mosquitoes are important parameters for prediction of the vector abundance. However, it should be realized that malaria infection and transmission is a complex mechanism, where non-environmental factors, including human behavior, demographic structure, landscape structure, and spatial relationships between human residence and the vector habitats, are also significant considerations in the framework of medical geography.

• Journal of The Korean Society of Agricultural Engineers
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• v.62 no.2
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• pp.63-73
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• 2020

Drought is considered as a devastating hazard that causes serious agricultural, ecological and socio-economic impacts worldwide. Fundamentally, the drought can be defined as temporarily different levels of inadequate precipitation, soil moisture, and water supply relative to the long-term average conditions. From no unified definition of droughts, droughts have been divided into different severity level, i.e., moderate drought, severe drought, extreme drought and exceptional drought. The drought severity classification defined the ranges for each indicator for each dryness level. Because the ranges of the various indicators often don't coincide, the final drought category tends to be based on what the majority of the indicators show and on local observations. Evaporative Stress Index (ESI), a satellite-based drought index using the ratio of potential and actual evaporation, is being used as a index of the droughts occurring rapidly in a short period of time from studies showing a more sensitive and fast response to drought compared to Standardized Precipitation Index (SPI), and Palmer Drought Severity Index (PDSI). However, ESI is difficult to provide an objective drought assessment because it does not have clear drought severity classification criteria. In this study, U.S. Drought Monitor (USDM), the standard for drought determination used in the United States, was applied to ESI, and the Percentile method was used to classify drought categories by severity. Regarding the actual 2017 drought event in South Korea, we compare the spatial distribution of drought area and understand the USDM-based ESI by comparing the results of Standardized Groundwater level Index (SGI) and drought impact information. These results demonstrated that the USDM-based ESI could be an effective tool to provide objective drought conditions to inform management decisions for drought policy.

• Journal of Environmental Impact Assessment
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• v.25 no.6
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• pp.442-456
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• 2016

The Secretariat of the Convention on Biological Diversity (SCBD) encourages the use of the City Biodiversity Index (CBI) as a monitoring tool to assist local authorities in evaluating their progress in urban biodiversity conservation. The CBI has been applied to conserve the city biodiversity. This study has developed the City Ecological Soundness Index (CESI) based on the CBI and Korean city characteristics. The CESI includes total of 12 indicators grouped in three categories, which are 'biodiversity,' 'ecosystem services' and 'governance and management.' 85 cities in Korea were classified according to the city size and type. 18 cities have applicable biotope map, which were analyzed in the CESI pilot study. The CESI will contribute to collect and manage biodiversity data systematically and to promote biodiversity-related actions.

• The Journal of the Korea Contents Association
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• v.17 no.4
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• pp.219-228
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• 2017

This study is designed as a non-equivalent controlled before-and-after quasi-experimental study by having a control group for the effect of the interpersonal caring music activity program in children of single-parent families. Data collection was carried out in 22 children of single-parent families as the study group and in 23 children as the control group recruited from 22 community centers for children located in N city from July to September, 2014. As the study tool, the Heart Rate Variability (HRV) was used to measure loneliness, self-esteem scale and the stress response. With the collected data and using SPSS 18.0 for Window program, the Homogeneity test between the study group and the control group was conducted by using t-test and ${\chi}^2$-test while the study hypotheses were verified by analyzing with the independent t-test. The results of the study are as follows. Loneliness and self-esteem of the subjects did not show significant difference in the study groups. The sympathetic nervous system activity (normalized LF) has been lowered and the parasympathetic nervous system activity (normalized HF) has been increased as the stress response, while the sympathetic and the parasympathetic nervous system activity ratio (LF/ HF) score was lowered with significant difference, which had supported the hypotheses. Based on these results of this study, the interpersonal caring music activity program can be utilized as a stress management program for the children of single-parent families during a short period of time.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.259-267
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• 2020

This study investigates the educational needs of parents of elementary school children, who use smartphones for emergencies. This is a descriptive cross-sectional study, and data of 200 parents of students under the 6th grade was collected from October 17 to 27, 2017. The study results indicate that 67.5% parents visited the emergency department due to a child's emergency accident. Of these, 74% respondents replied that they were unaware of how to deal with the emergency at that instance. Most parents had never received education, and were using smart-phones to acquire information on first aid. Ed. Notes: Do you mean education in general (i.e. Most parents were uneducated) or do you mean 'education for emergencies'? Please revise for more clarity. Parents' demand for education on child emergency response scored high, with an average of 3.40 (±0.42) out of 4 points. Among the educational categories, "the management of foreign body airway obstruction and cardiopulmonary resuscitation (CPR)" scored the highest average for educational needs (3.64±0.52). This research provides baseline information for understanding the educational needs of parents for first aid for the child. Our findings indicate that the smartphone is potentially an effective educational tool for parents.

• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.6
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• pp.647-653
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• 2016

There are no ex-port evaluations for the propriety and efficiency of AtoNs considering risk elements and environmental changes after the opening of a port. It is necessary to develop objective indicators and evaluation models to fill this gap. This study establishes an efficiency analysis model for Aids to Navigation (ANEffic) focusing on manned lighthouse, which include 20 function indices. After running a function assessment, an Analytic Hierarchy Process (AHP) and Likert scale are used to address port operations, national policies and expert opinions. As the result of the assessment, Yeongdo, Gageodo, Geomundo and Jukbyun Lighthouses are highly regarded in the propriety and efficiency of AtoN. And Uleungdo, Gasado, Songdaemal and Ulgi Lighthouses need to review detailed evaluations. The ANEffic developed should be utilized as basic tool to collect data for efficient management and to re-arrange the policy decisions regarding AtoNs as appropriate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.184-192
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• 2017

This study was a pilot test of serious educational game content(named Roly Poly 160) designed to enhance self-care by elderly diabetics. Roly Poly 160 was developed in eight steps (literature review, demand survey and consultation, extraction of serious content using games, development of Roly Poly 160, pretest for users, workshop for health care workers, final completion of Roly Poly 160 and user satisfaction survey of Roly Poly 160). Roly Poly 160 is intuitively structured in three modules (self-management, card games, and quiz games) that can be self-managed by the elderly and is designed based on six principles. First, we constructed an intuitive interface considering the age of users. Second, the menu was selected as the main menu for Koreans and calorie learning was made at the same time. Third, the calories and nutrients (carbohydrate, fat, protein, calcium, sodium) of selected foods are analyzed, and all test data recorded in the questionnaire chart are graphically displayed by year, month and week so that the change trends can be grasped at a glance. Fourth, necessary data were saved and output and used as educational data. Fifth, user data are made compatible and aggregated and up to 100 million members can be registered. Sixth, it is designed to be developed as a mobile app if necessary. Using Roly Poly 160, 119 diabetic patients were diagnosed with diabetes, and the satisfaction score was 4.26 out of 5. These findings indicate that Roly Poly 160 is appropriate as a diabetes self-care tool and suggests that there is a possibility to use it as a program to educate people about diabetes in public health centers, hospitals and clinics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.249-256
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• 2017

Luxury goods products have a steady stream of consumers, and the latest trend is the sell and purchase markets. The consumers age groups also vary widely. This research examined the mediating effect of self-construal of the relationship between brand consistency and intention to purchase luxury fashion products. The analysis classified the brand consistency of luxury fashion products as social, actual, and the deal. First, the order of consistency that had an effect on self-construal appeared in the order of social cohesion, actual coincidence, and ideal coincidence. Second, an analysis of mediating effect of self-construal showed that only self-construal appeared to have a partial mediating effect on the relationship between the intention to purchase and the actual and ideal consistency. Such result can be interpreted as that when purchasing luxury fashion products, consumers have a tendency to desire that the brand would express their personal image and that it would match the perception they had of the brand, rather than a tendency to perceive the brand as a tool to help them perform their desired social role. These results suggest that consumers who consume the brand desire to have their personalities and subjective environmental conditions well expressed.