• 생약학회지
• /
• 제43권4호
• /
• pp.265-267
• /
• 2012

Korean folk medicine 'JagSalNaMu' has been used orally to cure hypercoagulability, thrombosis and tonsillitis. With regard to the botanical origin of 'JagSalNaMu', it has been considered to be Callicarpa species of Verbenaceae, but there was no pharmacognostical confirmation on it. To clarify the botanical origin of 'JagSalNaMu', the anatomical characteristics of the branch of Callicarpa species growing wild in Korea, Callicarpa japonica and C. dichotoma were studied. As a result, it was clarified that 'JagSalNaMu' was the branch of Callicarpa japonica.

• 생약학회지
• /
• 제50권2호
• /
• pp.73-80
• /
• 2019

Adenophora stricta Miq. (Campanulaceae) is an annual herb, which has been used as a traditional medicine in Korea, Japan and China to treat bronchial asthma, tonsillitis, and hypertension. In this study, 12 compounds were isolated from the roots of A. stricta and isolates were identified to be methyl adenophorate (1), decursidin (2), L-tryptophan (3), D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid (4), vanillic acid 4-O-${\beta}$-D-glucopyranoside (5), syringic acid 4-O-${\beta}$-D-glucopyranoside (6), vanillin (7), vanillic acid (8), p-hydroxybenzaldehyde (9), p-hydroxybenzoic acid (10), p-hydroxyacetophenone (11) and linoleic acid (12). Decursidin (2) and D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid (4) is firstly reported from A. stricta in current study.

• 대한기관식도과학회:학술대회논문집
• /
• 대한기관식도과학회 1981년도 제15차 학술대회연제순서 및 초록
• /
• pp.11.2-11
• /
• 1981

이비인후과 영역에서의 결석증은 타영역에 비해서 비교적 드물게 발견된다. 편도 결석은 만성편도염 환자의 소여포를 채우고 있는 건락성 충진물의 중심부에서 발견된다. 어릴때 편도염을 자주 앓았던 성인에서 발견되는 것이 보통이고, 증상으로는 구개내 이물감 및 악취를 환자 자신이 느낀다. Keratohyalin이 축적되어 결석을 형성하고 있으며 염증이 동반되면 인두통, 인통, 연하통 연하곤란등이 있을 수 있다. 비석은 비강내 이물, 응혈, 세균 가피 농후한 분비물 등이 핵이 되어 그 주위에 칼슘, 마그네슘등이 침착해서 형성된다. 성인에 따라서 외인성과 내인성으로 구분되는데, 외인성의 경우는 비강내 이물에 의해서, 내인성의 경우는 기왕에 존재하던 비질환에 의해서 각각 비폐쇄가 유발되며, 비루에 지장이 초래되어 분비물의 울혈을 가져와서 비석을 형성하는데 기여한다. 성인, 여자에서 잘 생길 수 있으며 대개 편측성이고 비강저부에저 발견되는 것이 보통이다. 대개 완만한 성장을 보이므로 상당기간은 아무런 증상없이 지내다가 비폐쇄, 비출혈, 악취나는 점액농성 분비물을 주소로 내원하는 수가 많다. 저자들은 이비인후과 영역에서도 희귀하게 발견되는 편도결석 1례와 거대한 비석 1례를 최근에 치험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국컴퓨터정보학회논문지
• /
• 제21권5호
• /
• pp.135-139
• /
• 2016

Scrophularia ningpoensis hemsl has been traditionally used in China and Vietnam for treatment of bacteria, atopy, pimple, tonsillitis, angina and encephalitis for a long time. The main objectives of this study were to evaluate the antibacterial activity of the Scrophularia ningpoensis hemsl extract on biofilm formation of Klebsiella pneumoniae. Antibacterial activity was conducted using disc diffusion assay and minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) were determined using the broth micro dilution method in accordance to Clinical and Laboratory Standards Institute guidelines(CLSI). Furthermore, cytotoxicity on L929 were assessed using animal cell culture for the proliferation test(MTT cell assay) and the biofilm forming capacity of the K. pneumoniae were determined using the colony forming unit (CFU) assay. The extract exhibited considerable antibacterial activity. K. pneumoniae was susceptible to the extract with the MIC and MBC of 0.1875 and $1.5mg/m{\ell}$ respectively. Cytoxicity test in L929 showed no sign of toxicity at the concentration of $0.75mg/m{\ell}$ and at the same concentration the extract caused inhibition of bacterial biofilm formation. The extract of Scrophularia ningpoensis hemsl possesses an in vitro antibacterial antibiofilm activities against K. pneumoniae, with no sign of cytoxicity on L929.

• 대한한의학회지
• /
• 제34권3호
• /
• pp.160-168
• /
• 2013

편도선염을 앓고 난 후 발병한 소양인 건선환자 2례와 스테로이드 중단에 의한 리바운드 현상으로 심해진 소양인 건선환자 2례는 피부증상과 병증(病證)의 양상이 소양인 위수열리열병(胃受熱裏熱病)의 양독발반(陽毒發斑)의 증상과 유사하였다. 특히 변비(便秘) 구갈(口渴) 다한출(多汗出)과 같은 위열(胃熱)의 증상과 수족부의 심한 건선 병변이 공통된 증상으로 나타났다. 이에 소양인 위수열리열병(胃受熱裏熱病) 양독발반(陽毒發斑) 변폐(便閉)에 사용하는 양독백호탕(陽毒白虎湯)과 두면사지(頭面四肢) 청양불승(淸陽不升)에 사용하는 양격산화탕(陽隔散火湯)을 투여하여 유효한 치료효과를 얻었기에 치험례로 보고하였다. 향후 건선의 다양한 종류와 발병과정에 따른 사상의학적 치료에 대한 연구가 이어지길 바라며 난치질환인 건선의 치료에 도움이 되기를 기대한다.

• 대한수의학회지
• /
• 제42권3호
• /
• pp.383-387
• /
• 2002

A four-year-old male elk (Cervus elaphus nelsoni) was diagnosed as pulmonary aspergillosis and renal oxalosis. Clinical signs were coughing, sneezing, respiratory distress, salivation, moderate anorexia, and progressive emaciation. Main gross lesions were fibrinopurulent tonsillitis, diffusely fibrinous pleuritis, and distinct lobar pneumonia with purple red in color. Most of the pulmonary lobes had numerous well demarcated 0.5 to 2 cm yellowish white discrete or confluent nodules that were surrounded by pale red zones. Histopathologically, the affected lungs were disseminated necrotizing pyogranulomas including fungal hypae, vasculitis, and diffusely fibronecrotic pleuritis. The renal lesions were composed of extensive tubular necrosis with large numbers of rosette-formation by birefringent oxalate crystals. Aspergillus fumigatus was isolated from lesions of the lungs. It seems to be a first report for pulmonary aspergillalis and renal oxalosis of a farmed elk in Korea.

• The Korean Journal of Pain
• /
• 제10권1호
• /
• pp.54-57
• /
• 1997

Background : The tonsillar region is innervated by the sensory components of the glossopharyngeal nerve(IX) which communicates with certain part of cervical sympathetic ganglion. Some authors suggest stellate ganglion block(SGB) is effective for treatment of recurrent tonsillitis. The goal of this study was to evaluate the effect of SGB in controlling pain after tonsillectomy. Methods : Forty five patients, evaluated to ASA class 1 and 2, scheduled for tonsillectomy under general anesthesia were randomly assigned to 1 of 3 groups (group I: control; group II: SGB with 1% lidocaine 5 ml; group III: SGB with 2% lidocaine 2.5 ml plus 0.5% bupivacaine 2.5 ml), SGB was performed at the end of surgery. Postoperative pain was assessed with Numeric Rating Scale(NRS) NRS assessment was made 30, 60, 90 min, 2 h, 4 h, 24 h, 48 h after tonsillectomy. Results : Pain scores, after 30 min in group II, III and 60, 90 min in group III were significantly lower than group I(p<0.05). Conclusions : We found SGB was effective in controlling pain after tonsillectomy but further studies are required needs to prolong duration of relief..

• 생약학회지
• /
• 제42권1호
• /
• pp.15-21
• /
• 2011

Scrophulariae Radix (Scrophulariaceae) has been traditionally used to treat pharyngitis, laryngitis, tonsillitis, fever, and edema. To compare the quality of the Scrophulariae Radix produced from Gyeongbuk with that from China, a quantitative analysis on the major component, E-harpagoside, was performed by reversed-phase HPLC, and a relative inhibitory activity of nitric oxide (NO) was assayed in the Raw 264.7 cells. Using a Luna $C_{18}$(2) column, we carried out quantitative analysis with a gradient of 0.1% phosphoric acid in water and acetonitrile. Our results demonstrated that the content of E-harpagoside in Gyeongbuk's Scrophulariae Radix were three times higher than that of Chinese. Moreover, the inhibitory activity of Scrophulariae Radix of Gyeongbuk's in the lipopolysaccharide (LPS)-induced NO production was higher than that of Chinese.

• Journal of Chest Surgery
• /
• 제7권1호
• /
• pp.79-84
• /
• 1974

Acute suppurative pericarditis is recognized as a rare disease since development of antibiotics but therapeutically as an important one. To our knowledge, acute suppurative pericarditis alone has not been reported previously in Korea. In this paper, we report 5 cases of acute suppurative pericarditis which were experienced during the period between January 1959 and December 1973. The patients ranged in age from 9 months to 59 years at the time of admission. Four of 5 patients were male and one female. Acute suppurative pericarditis is usually associated with pneumonia, empyema, sepsis, osteoarthritis, lung abscess, cholecystitis or tonsillitis. In our series, pneumonia was the most common associated disease. One patient had osteoarthritis. Pleural effusions were observed in three of the 5 patients. Staphylococcus aureus was cultured from pericardial fluid in 4 patients and also cultured from both pericardial and synovial fluid in one. Three of the 5 patients had cardiac tamponade and one patient required prompt pericardiocentesis. 3 of the 5 patients were treated with antibiotics and pericardiostomy, one with antibiotics and pericardiocentesis, and one with antibiotics and saline irrigation through drainage sinus from the pericardial sac. Four of the five patients were recovered without pericardial constriction. One was discharged with poor condition. In this instance, follow-up study couldn`t be made.

• 대한한방소아과학회지
• /
• 제30권2호
• /
• pp.47-55
• /
• 2016

Objectives The purpose of this study is to investigate recent clinical studies on the effect of acupuncture on sore throat. Methods Based on the PubMed search with the key search terms of 'sore throat, acupuncture', dated from 1992 to 2015, 7 controlled trials and 8 case series was found, and were analyzed for this study. Results 1. The most commonly used acupoints were Quchi (LI11), and Hegu (LI4). 2. The most commonly used meridians were The Lung Meridian of Hand-Taiyin and The Large Intestine Meridian of Hand-Yangming. 3. Acupuncture treatment was effective for both acute and chronic sore throat. 4. More clinical studies are needed to prove the effectiveness of the acupuncture on sore throat. To be more objective on the study results, we can measure temperature drops on or amount of analgesic consumption for sore throat after acupuncture treatment.