• Title/Summary/Keyword: To-Tc method

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Brown Tumors Due to Parathyroid Carcinoma; $^{99m}Tc-MIBI$ Scan Findings (Case Report) (부갑상선 암종에 의해 발생한 갈색 종양: $^{99m}Tc-MIBI$ 스캔 소견 (증례 보고))

  • Kim, Su-Zy;Yoon, Soek-Nam;Kim, Byung-Soek;Chung, Yoon-Soek;Park, Chan-Hee
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.395-398
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    • 1997
  • Whole body $^{99m}Tc-MIBI$ scan in conjunction with parathyroid scan is an effective method in detecting parathyroid lesions in patients with bone pain and possible bone lesions such as brown tumors.

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Magnetism and Electronic Structure of Tc Half-monolayer on Pd(oo1) Surface (Pd(001) 위에 올려진 Tc 0.5 웃층의 자성과 전자구조)

  • 김동철;이재일
    • Journal of the Korean Magnetics Society
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    • v.9 no.5
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    • pp.223-226
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    • 1999
  • We have investigated the magnetic properties and the electronic structures of Tc half-monolayer (0.5-ML) on Pd(001) using the full-potential linearized augmented plane wave(FLAPW) energy band method. We calculated the total energies for ferromagnetic and paramagnetic states to determine the stable magnetic state. The calculated results show that the total energy of the ferromagnetic state is lower than that of the paramagnetic one. The overlayer Tc 0.5-ML has considerably large magnetic moment $(2.09\;{\mu}_B)$, while the substrate Pd layers have been negatively polarized. The calculated density of states and total electrons inside the muffin-tin (MT) sphere are presented and discussed in relation with the magnetic properties.

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A Study on the Thyroid Scan Images by Different Radionuclides ($^{99m}Tc$ pertechnetate and $^{131}I$) and Multiple Views (사용핵종(使用核種) 및 주사방향(走査方向)에 따른 갑상선주사상(甲狀腺走査像)의 차이(差異)에 관한 연구(硏究))

  • Whang, Il-Yong;Chung, Soon-Il;Kim, Dong-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.20 no.1
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    • pp.53-58
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    • 1986
  • Thyroid scans using $Na^{131}I\;and\;^{99m}TcO_4^-$ in two (anterior and anterior oblique) projections were done simultaneously in 50 patients with single palpable nodule and in euthyroid state(nodular nontoxic goiter) and 20 normal subjects to evaluate the imaging ability of each radionuclide and the necessity of oblique view. In detection of a nodule as a cold or cool area, $^{99m}TcO_4^-$ was slightly superior to $^{131}I$(82 % to 78% with anterior view alone, 92% to 84% when oblique view is added in detectability), with addition of an oblique view, 5 more cold or cool area in $^{99m}Tc$ scan and 3 more $^{131}I$ scan were detected. In normal subjects $^{99m}TcO_4^-$ scan was significantly superior to $^{131}I$ scan(90% to 70%) in getting normal pattern of tracer uptake in the glands. For routine imaging study of the thyroid, $^{99m}Tc$ pertechnetate scan with multiple projection is considered to be a preferable method.

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Thallium-201 Scan in Bone and Softtissue Sarcoma - Comparison with Tc-99m-MIBI and Tc-99m-MDP Scan - (악성 골 및 연부조직 종양에서 Tl-201 SCAN의 진단적 효능 - Tc-99m-MIBI 및 Tc-99m-MDP scan과의 비교 -)

  • Shin, Duk-Seop;Cho, Ihn-Ho;Ahn, Jong-Chul;Ahn, Myun-Hwan;Lee, Sang-Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.2 no.1
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    • pp.1-7
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    • 1996
  • PURPOSE : The purpose of this study is to know the ability of detecting malignant tumor tissue by Tl-201 scan, and to compare with that of Tc-99m-MIBI and Tc-99m-MDP scan. MATERIAL AND METHODS : Between February 1994 and December 1995,38 unselected patients with various bone pathologies were studied prospectively. Eighteen had malignant bone and soft tissue pathologies, while twenty had benign. All patients were studied with Tl-201, Tc-99mMIBI and Tc-99m-MDP scan prior to surgical biopsy. PICKER Prism 2000 gamma camera with high resolution parallel hole collimator was used for scanning. To avoid the interaction of isotope, the early(30min.) and delayed phase(3hrs.) of Tl-20l scan was performed first and Tc-99m-MIBI scan was performed after 30 minutes, and then Tc-99m-MDP scan 48 hours later. The scan images were visually evaluated by a blinded nuclear medicine physician. We could find true positive, true negative, false positive and false negative by the comparison of results with those of biopsy. We calculated positive and negative predictive value(%), sensitivity(%), specificity(%) and diagnostic accuracy(%) of each scan. RESULT : The results of each scan were 85.7, 100, 100, 85, 92.1% in Tl-201, 81, 94.1, 94.4, 80, 86.8% in Tc-99m-MIBI and 50, 66.7, 88.9, 20, 52.6% in Tc-99m-MDP scan. As a conclusion, Tl-201 scan was the most specific and accurate method for detecting malignant tumor tissue. Tc-99m-MIBI scan was also good for malignant tumor searching. CONCLUSION : With our results, we can use Tl-201 scan to differentiate benign from malignant tumor, and to evaluate the response of preoperative chemotherapy or radiotherapy, and to determine the residual tumor or local recurrence. For the better result, we need to have a more detail information about false positive cases and a more objective and quantitative reading technique.

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Analysis of Cell Variation of ATM Transmission for the Poisson and MMPP Input Model in the TDMA Method (TDMA 방식에서 포아송 입력과 MMPP 입력 모델에 따른 ATM 전송의 셀 지연 변이 해석)

  • Kim, Jeong-Ho;Choe, Gyeong-Su
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.3
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    • pp.512-522
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    • 1996
  • To provide broadband ISDN service for the users in scattered locations, the application of satellite communications network is seriously considered. To trans mit ATM cells efficiently in satellite communications, it is effective to use TDM A method. However, it is necessary to have a method to compensate the cell delayvari-ation caused by the difference between TDMA and ATM. This paper optimized the cell control time(Tc) when traffic inputs have poisson or markov modulated poisson process by applying cell delay variation characteristics of time stamp method, which has the most advantages among compensation methods or cell delay variation. This paper also intorduces a method of reducing the cell clumping phenomena by adapting discrete time stamp method, including the analysis and evalutation of the range of required quality of CDV distribution by ATM transmission.The result of the experiment shows that CDV distribution-range can be controlled to 1.2$\times$Tc which reduces overall cell delay variation by discrrete time stamp method.

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$Site-Specific^{99m}$Tc-Labeling of Antibody Using Dihydrazinoph-thalazine (DHZ) Conjugation to Fc Region of Heavy Chain

  • Jeong, Jae-Min;Lee, Jae-Tae;Paik, Chang-Hum;Kim, Dae-Kee;Lee, Dong-Soo;Chung, June-Key;Lee, Myung-Chul
    • Archives of Pharmacal Research
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    • v.27 no.9
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    • pp.961-967
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    • 2004
  • The development of an antibody labeling method with $^{99m}$Tc is important for cancer imaging. Most bifunctional chelate methods for $^{99m}$Tc labeling of antibody incorporate a $^{99m}$Tc chelator through a linkage to lysine residue. In the present study, a novel site-specific $^{99m}$Tc labeling method at carbohydrate side chain in the Fc region of 2 antibodies (T101 and rabbit anti-human serum albumin antibody (RPAb)) using dihydrazinophthalazine (DHZ) which has 2 hydrazino groups was developed. The antibodies were oxidized with sodium periodate to pro-duce aldehyde on the Fc region. Then, one hydrazine group of DHZ was conjugated with an aldehyde group of antibody through the formation of a hydrazone. The other hydrazine group was used for labeling with $^{99m}$Tc. The number of conjugated DHZ was 1.7 per antibody. $^{99m}$Tc labeling efficiency was 46-85% for T101 and 67∼87% for RPAb. Indirect labeling with DHZ conjugated antibodies showed higher stability than direct labeling with reduced antibodies. High immunoreactivities were conserved for both indirectly and directly labeled antibodies. A biodistribution study found high blood activity related to directly labeled T1 01 at early time point as well as low liver activity due to indirectly labeled T101 at later time point. However, these findings do not affect practical use. No significantly different biodistribution was observed in the other organs. The research concluded that DHZ can be used as a site-specific bifunctional chelating agent for labeling antibody with $^{99m}$Tc. Moreover, $^{99m}$Tc labeled antibody via DHZ was found to have excellent chemical and biological properties for nuclear medicine imaging.edicine imaging.

Greenhouse Gas Inventory in Land-Use Change and Forestry in Korea (임업 및 토지이용부문의 온실가스 흡수 및 배출 현황)

  • 이경학;손영모;김영수
    • Journal of Korea Foresty Energy
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    • v.20 no.1
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    • pp.53-61
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    • 2001
  • An approach method for the greenhouse gas inventory in land-use change and forestry in Korea based on the 1996 revised IPCC(Intergovernmental Panel on Climate Change) guideline was developed and carbon budget of the year 1998 in this sector was estimated using the developed method as follow. For the category of changes in forests and other woody biomass stocks, carbon removal from the atmosphere by growth was 11,911 thousands TC(tons of carbon), carbon emissions to the atmosphere by harvests was 824 thousands TC, and net carbon removals was, therefore, 11,087 thousands TC, Emissions from decay of biomass remained after conversion of forest land to other land uses was estimated to 82 thousands TC For the category of land-use change and management, carbon emissions in mineral soils from land-use change was 1,025 thousands TC, that from liming of agricultural soils was 32 thousands TC, and total emissions was, therefore, 1,057 thousands TC. In summary, the carbon budget of land-use change and forestry of the year 1988 was as follows; the removal of 11,911 thousands TC, the emissions of 1,963 thousands TC, and the net removal of 9,948 thousands TC which was 9.6% of the emissions of 103,601 thousands TC from energy sector of the same year.

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Review of the approach in the PNF and Tai Chi on frail elders (허약한 노인을 위한 고유수용성 신경근 촉진법과 타이치의 적용에 관한 고찰)

  • Cho, Jeong-Sun;Bae, Sung-Soo;Park, Rae-Joon
    • PNF and Movement
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    • v.5 no.1
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    • pp.29-35
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    • 2007
  • Purpose : The purpose of this study was investigated to find the approach in the PNF and TC for frail elder Method : This is a literature study with books, articles, seminal note and books for PNF and TC international course. Result : Neural mechanisms contribute significantly to the gains that occur in the range of motion about a joint with stretching exercises. The participation in a stretch-training program decreases tonic reflex activity and increases flexibility and decreases in force production and muscle activation. Also the stretching-induced decreases may be due to a central nervous system inhibitory mechanism. PNF stretch techniques can increase ROM in older adults. These results may differ from those of studies performed with younger populations because of age-related physiologic changes. TC exercise improves balance control and muscle strength and were associated with reorganized lower extremity neuromuscular patterns. Conclusions : The stretch training program of the PNF and TC contribute to increase the balance and coordination for frail elder. Therefore, The frail elder prevent falling. Further study, The PNF and TC be introduced as the new therapeutic intervention for frail elder.

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Scintigraphic Assessment of Hepatobiliary Functions in Healthy Miniature Pigs (건강한 미니돼지에서 간담도 기능의 핵의학적 평가)

  • Kim, Se-Eun;Shim, Kyung-Mi;Yoo, Kyeong-Hoon;Lee, Won-Guk;Choi, Seok-Hwa;Park, Soo-Hyun;Han, Ho-Jae;Kang, Seong-Soo
    • Journal of Veterinary Clinics
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    • v.24 no.4
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    • pp.593-596
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    • 2007
  • The purpose of this study is to investigate normal hepatobiliary functions in healthy miniature pigs. $^{99m}Tc-DISIDA$ hepatobiliary scintigraphy(HBS) was used for it. Five mCi dose of $^{99m}Tc-DISIDA$ was injected intravenously into 3 healthy adult miniature pigs, and dynamic images were obtained during 1 hour. $^{99m}Tc-DISIDA$ HBS in a miniature pig was evaluated for 6 variables. A cardiac washout occurred within 1 min in all miniature pigs and radioactivities in the gallbladder were not detected in two miniature pigs. Thus, the initial radioactivity and Tmax of the gallbladder were non-available to identify. Mean Tmax of liver was $8.67{\pm}2.08$ min and initial small intestinal radioactivity was seen at $9.67{\pm}2.52$ min after $^{99m}Tc-DISIDA$ injection. Mean hepatic washout time was not detected in 60 min dynamic images. Therefore, $^{99m}Tc-DISIDA$ HBS is the effective diagnostic method to evaluate the function of hepatocyte and bile flow rate. However, it was not a proper method to evaluate the function of gallbladder, which indicates that an additional study is needed to further specify the reasons for the absence of radioactivities in gallbladder of two miniature pigs.

Fabrication of BSCCO High Tc Superconducting Precursor Using Chemical Process (화학 공정법에 의한 세라믹 Nanocomposite 합성)

  • Lee, Sang-Heon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.11a
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    • pp.390-391
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    • 2006
  • A high Tc superconducting with a nominal composition of $Bi_2Sr_2Ca_2Cu_3O_y$ was prepared by the citarte method. The solid precursor produced by the dehydration of the gel at $120^{\circ}C$ for 12h is not in the amorphous state as expected but in a crystalline state X-ray diffraction peaks of nearly the same angular position as the peaks of high Tc phase were observed in the precursor. After pyrolysis at $400^{\circ}C$ and calcination at $840^{\circ}C$ for 4h, the (001)peak of the high Tc phase was cleary observed. Experimental results suggest that the intermediate phase formed before the formation of the superconducting phase may be the most important factor in determining whether it is easy to form the high Tc phase or not, because the nucleation bafflers of the two superconducting phase may be altered by the variation of the crystal structures of those Intermediate phase.

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