• Toxicological Research
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• v.16 no.2
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• pp.95-100
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• 2000

In previous study, both constitutive expression and 3-methylcholanthrene (3MC)-mediated elevation of CYP1A2 mRNA were demonstrated in human hepatoma HepG2 cells by reverse transcription-polymerase chain reaction (RT-PCR), suggesting that HepG2 cells would be appropriate for the study of human CYP1A2 regulation(Chung and Bresnick, 1994). Further studies were conducted to determine the basis of this induction phenomenon that is observed in HepG2 cells. Since CYP1A1 gene, another polycyclic hydrocarbon(PH)-inducible gene, is regulated by PHs through their interactions via receptors with cis-elements, the 5'-flanking region of human CYP 1A2 gene was analyzed to search such responsive elements. The promoter activity of various lengths of CYP1A2 gene sequence (-3203/+58bp) was measured in transiently-transfected HepG2 cells by fusion constructs containing the CAT, hGH or luciferase genes as a reporter. This region of the CYP1A2 gene, although containing a XRE, was only weakly responsive (less than 2 fold induction) to 10 nM of TCDD or 1 $\mu$M 3 MC treatment. This small enhancement of promoter activity is inconsistent with the previous observation, i.e., 12 to 14 fold-enhanced CYP1A2 mRNA from 1 $\mu$M 3 MC treated HepG2 cells, suggesting that additional mechanisms would exist for PH-mediated induction of CYP1A2 in these cells.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.64 no.4
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• pp.303-307
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• 2015

The effects of additive such as $H_2O_2$ in KOH electrolyte solution for the Aluminum/Air fuel cell were investigated with regard to electric power characteristics. The power generated by a Al/Air fuel cell was controlled by the KOH electrolyte solution and $H_2O_2$ depolarizer. Higher cell power was achieved when higher KOH electrolyte concentration and higher $H_2O_2$ depolarizer amount. The maximum power was increased by the increase amount $H_2O_2$ depolarizer, it was found that $H_2O_2$ depolarizer inhibits the generation of hydrogen and the polarization effect was reduced as a result. Internal resistance analysis was employed to elucidate the maximum power variation. Higher internal resistance created internal potential differences that drive current dissipating energy. In order to improve the output characteristics of the Al/Air fuel cell, it is thought to be desirable to increase the KOH electrolyte concentration and increase the $H_2O_2$ addition amounts.

• Tribology and Lubricants
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• v.23 no.2
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• pp.66-72
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• 2007

[ $MoS_2$ ], is a well-known metal sulfide applied as solid lubricants and an additive to prolong the life of sintered bearings under severe conditions. However, the high price of $MoS_2$ limited its wide application. This study is aimed to investigate the possibility far application to solid lubricants for $Cu_2S$ as a substitute of $MoS_2$. Bronzes added $Cu_2S$ and $MoS_2$, are produced by powder metallurgy in this study, and then evaluated their friction and wear properties., as well as sintered bronze. The sliding wear test using pin-on-disc type machine, was conducted at several sliding speeds for three type test pieces sintered bronzes added $Cu_2S$ and $MoS_2$, and sintered bronze without lubricants. Addition of $Cu_2S$ to bronze leads to relatively good friction properties, although it is not so good as addition of $MoS_2$. However, the wear properies of sintered bronze added $Cu_2S$ are better than that of sintered bronze added $MoS_2$.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.1
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• pp.55-61
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• 2011

In this paper, the outage probability of device-to-device (D2D) uplink communication underlaying cellular networks is analyzed over Rayleigh fading. We assume that a D2D pair and M cellular user equipments share the same frequency resources. To prevent any harmful interference from a D2D transmitter to the BS, the maximum transmit power of the D2D transmitter is strictly limited. Under these assumptions, the outage probability is represented as a function of the interference-to-signal ratio from M cellular user equipments to a D2D receiver and the number of cellular user equipments, M. In addition, the interference-to-signal ratio is represented as a function of distances among D2D equipments, cellular user equipments and the BS. Simulation results validate these analytical results.

• Journal of Microbiology and Biotechnology
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• v.33 no.3
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• pp.356-362
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• 2023

The 2'-fucosyllactose (2'-FL) is the richest components in a human milk oligosaccharide. Several studies have reported that 2'-FL has beneficial effects in infants. However, there are few studies on its immune-enhancing effects. This research aimed to examine the immune-enhancing effect of 2'-FL on immunosuppression by cyclophosphamide (CCP) in ICR mice. Mice were orally administered distilled water or 0.5 mg/kg B.W. 2'-FL for 14 days. An immunocompromised mouse model was induced using CCP 80 mg/kg B.W. at 12-14 days. Using the CCP had effects on reducing their body weight, organ weight, spleen index, natural killer (NK) cell activity, and cytokines concentration and expression. This study also used concanavalin A-mediated T-cell proliferation to verify the immune-enhancing effects in the sample. Body weight, spleen index, organ weight, and cytokine levels were measured to estimate the immune-enhancing effects. The body weight at 14 days tended to increase, and the spleen weight and index significantly increased in the 2'-FL group compared to the CCP group. The NK cell activity increased in the 2'-FL group compared to the CCP group, but there was no significant difference. The concentration of interleukin (IL)-2 tended to recover in the 2'-FL group compared to the CCP group. The 2'-FL group showed a significant increase of IL-10 and IFN-gamma concentration compared to the CCP group. In addition, there was a trend of increased IL-10 mRNA expression compared to the CCP group. These results revealed that 2'-FL improved CCP-induced immunosuppression, suggesting that 2'-FL may have the potential to enhance the immune system.

• Journal of the Korean Chemical Society
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• v.50 no.5
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• pp.369-373
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• 2006

Arylation reactions of styrene catalyzed by Pd(CF3CO2)2-sulfides and Pd(CF3CO2)2-phosphines were investigated. The yield of trans-stilbene, the main product, increased as the basicity of the substituents on the aryl groups of the phosphines increased and the steric hindrance of the substituents decreased. The mechanism of the aryl migration of arylphosphines to styrene is proposed to involve the electrophilic attack of Pd to the phenyl group on the phosphines. The phosphine systems were found to be more effective than the sulfide ones.

• IEMEK Journal of Embedded Systems and Applications
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• v.3 no.4
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• pp.218-228
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• 2008

The convergence of broadcasting and telecommunication services is being accelerated by broadband networks, digital broadcasting and Web2.0. This paper describes the definition and service characteristics of IPTV as a representative of broadcasting and telecommunication convergence services. Especially, the changes of infrastructure and technology for IPTV2.0 are addressed in terms of the service features of mobility, intelligence and participation. IPTV2.0 shall be characterized by the open IPTV service based on Web2.0 and the mobile IPTV service over the heterogeneous networks employing various wireless/wired access technologies. The IP Multimedia Subsystem (IMS) and Service Delivery Platform (SDP) technologies are increasingly considered to support the personalization and openness. The mobility management technology is being evolved to provide QoS-guaranteed mobile communication services to users at anytime and anywhere. IPTV2.0 services and platforms are also anticipated to be core components to achieve knowledge-based ubiquitous society. IPTV2.0 contents are required to be integrated with the enhanced metadata to efficiently support search, selection, convergence and delivery of the contents. Moreover, those contents shall be enhanced to provide the scalable services which is adaptable to the network status and user preferences. Therefore, the networking technologies for IPTV2.0 should tightly cooperate with application services and adaptive contents. Those technologies will be developed to construct the ubiquitous content service platform considering the evolution of networks and various converged services.

• Phonetics and Speech Sciences
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• v.10 no.1
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• pp.65-74
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• 2018

The purpose of this study is to investigate age-specific features of 2;1- to 4;1-year -olds' production of monophthongs and diphthongs through both auditory perceptual analysis and acoustic analysis. Test material included {vowel+'da'} consisting of 7 monophthongs and 10 diphthongs and meaningful words beginning with vowels. The percentage of correct vowels was used for perceptual analysis and Praat(5.2.12) was used for acoustic analysis, analyzing variables related to monophthongs and diphthongs. The results of this study are as follows: First, perceptual analysis showed that children from an age group of 2;1 to 2;8 years showed significant difference in the accuracy level of both monophthongs and diphthongs as compared to those aged 2;9 to 3;4 years and those aged 3;5 to 4;1 years. Second, the results of acoustic analysis provided that formant (F1 and F2) of monophthong, in general, tended to decrease as age increased. In terms of F2 differentiation slope and regression slope, which were diphthong-related variables, the age group of 3;5 to 4;1 years showed a large general slope change.

• KIEAE Journal
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• v.15 no.5
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• pp.89-94
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• 2015

Purpose: Various policies to reduce the energy consumption have been carried out to save Earth environment against global warming and environmental pollution in many countries. Energy consumption of buildings in Korea has reached 24% of total energy consumption, and energy consumption of apartment has been continuously increasing. Therefore, Korea government has executed building energy efficiency rating certification system to control energy consumption of buildings. Method: This study was conducted to evaluate the energy performance of apartment unit plans according to the increasement of front width of unit plans, and tried to present the basic data to design more energy conscious unit plans for apartments. For the study, three shapes of unit plans -the 2Bay, 3Bay and 4bay unit- were selected for imput models. They were simulated using ECO2 software to assess building energy efficiency rating certification in Korea. Result: According to the results, in cases that balcony windows were not installed, the primary energy consumption of the 3Bay and 4Bay units were less than 2Bay unit, respectively, 0.1% and 2,5%. The primary energy consumption of the 3Bay and 4Bay units, in cases that balcony windows were installed, was less than 2Bay unit, respectively, 1.7% and 3.2%.

• Journal of Information Technology Services
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• v.6 no.3
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• pp.69-86
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• 2007

As most of firms related with P2P services change their free services into fee-charging services, the problems of intellectual property rights are solved to satisfactory extent. Accordingly, P2P systems become more popular with the general public. In this respect, it is thought to be very important to research on the critical factors affecting usage of P2P systems. Although it is strongly expected that the characteristics of users activities in virtual communities affect the intention to re-use P2P systems, relatively few attention have been paid to this question. Therefore, this paper is to present empirical evidence to explain how the characteristics of users activities in virtual communities affect re-use intention of P2P services. The theoretical contribution of this study is that the characteristics of users activities in virtual communities is theoretically derived from the comprehensive literature review and the logical reasoning, and that the research model of the relationship between the users activities' characteristics in virtual community and the re-use intention of P2P services is proposed and empirically validated, which is expected to expand explaining power of the TAM(Technological Acceptance Model). Also, the practical implication is to provide the guideline to support the successful strategic planning for development and.operation of P2P services through the virtual communities.