• The Journal of the Acoustical Society of Korea
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• v.34 no.1
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• pp.1-11
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• 2015

Salinity affects sound speed in the low salinity environment, in the seas where freshwater from large rivers and flows into the marginal sea area near the Yangtze River and the Niger River. In this paper, SSC (Surface Sound Channel) formed by low salinity water was investigated in the East China Sea and the Gulf of Guinea of rainy season. The data from KODC (Korea Oceanographic Data Center) in the East China Sea and from ARGO (Array for Real-time Geostrophic Oceanography) in the Gulf of Guinea of the tropical area were used for analysis. SSC haline channel was formed 14 times among 32 SSC occurrences when the 90 data from 9 points were analyzed during a decade (2000 ~ 2009) in the East China Sea. In the Gulf of Guinea, haline channel was formed 18 times among 20 SSC occurrences during 3 years (2006 ~ 2009). When the sound speed gradient was analyzed from temperature-salinity gradient diagram, the gradients of both salinity and temperature affect SSC formation in the East China Sea. In contrast, the salinity gradient mostly affects SSC formation due to the least change of temperature in the well-developed mixed layer in the Gulf of Guinea. Their acoustic characteristics show that channel depth is 6.5 m, critical angle is $1.5^{\circ}$ and difference of transmission loss between surface and thermocline is 11.5 dB in the East China Sea, while channel depth is 18 ~ 24 m, critical angle is $4.0{\sim}5.4^{\circ}$ and difference of transmission loss is 21.5 ~ 27.9 dB in the Gulf of Guinea. These results are expected to be used as a basic understanding of the acoustic transmission changes due to low salinity water at the estuaries and the ocean with heavy precipitation.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.88-89
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• 2013

A variety of influenza A viruses from animal hosts are continuously prevalent throughout the world which cause human epidemics resulting millions of human infections and enormous industrial and economic damages. Thus, early diagnosis of such pathogen is of paramount importance for biomedical examination and public healthcare screening. To approach this issue, here we propose a fully integrated Rotary genetic analysis system, called Rotary Genetic Analyzer, for on-site detection of influenza A viruses with high speed. The Rotary Genetic Analyzer is made up of four parts including a disposable microchip, a servo motor for precise and high rate spinning of the chip, thermal blocks for temperature control, and a miniaturized optical fluorescence detector as shown Fig. 1. A thermal block made from duralumin is integrated with a film heater at the bottom and a resistance temperature detector (RTD) in the middle. For the efficient performance of RT-PCR, three thermal blocks are placed on the Rotary stage and the temperature of each block is corresponded to the thermal cycling, namely $95^{\circ}C$ (denature), $58^{\circ}C$ (annealing), and $72^{\circ}C$ (extension). Rotary RT-PCR was performed to amplify the target gene which was monitored by an optical fluorescent detector above the extension block. A disposable microdevice (10 cm diameter) consists of a solid-phase extraction based sample pretreatment unit, bead chamber, and 4 ${\mu}L$ of the PCR chamber as shown Fig. 2. The microchip is fabricated using a patterned polycarbonate (PC) sheet with 1 mm thickness and a PC film with 130 ${\mu}m$ thickness, which layers are thermally bonded at $138^{\circ}C$ using acetone vapour. Silicatreated microglass beads with 150~212 ${\mu}L$ diameter are introduced into the sample pretreatment chambers and held in place by weir structure for construction of solid-phase extraction system. Fig. 3 shows strobed images of sequential loading of three samples. Three samples were loaded into the reservoir simultaneously (Fig. 3A), then the influenza A H3N2 viral RNA sample was loaded at 5000 RPM for 10 sec (Fig. 3B). Washing buffer was followed at 5000 RPM for 5 min (Fig. 3C), and angular frequency was decreased to 100 RPM for siphon priming of PCR cocktail to the channel as shown in Figure 3D. Finally the PCR cocktail was loaded to the bead chamber at 2000 RPM for 10 sec, and then RPM was increased up to 5000 RPM for 1 min to obtain the as much as PCR cocktail containing the RNA template (Fig. 3E). In this system, the wastes from RNA samples and washing buffer were transported to the waste chamber, which is fully filled to the chamber with precise optimization. Then, the PCR cocktail was able to transport to the PCR chamber. Fig. 3F shows the final image of the sample pretreatment. PCR cocktail containing RNA template is successfully isolated from waste. To detect the influenza A H3N2 virus, the purified RNA with PCR cocktail in the PCR chamber was amplified by using performed the RNA capture on the proposed microdevice. The fluorescence images were described in Figure 4A at the 0, 40 cycles. The fluorescence signal (40 cycle) was drastically increased confirming the influenza A H3N2 virus. The real-time profiles were successfully obtained using the optical fluorescence detector as shown in Figure 4B. The Rotary PCR and off-chip PCR were compared with same amount of influenza A H3N2 virus. The Ct value of Rotary PCR was smaller than the off-chip PCR without contamination. The whole process of the sample pretreatment and RT-PCR could be accomplished in 30 min on the fully integrated Rotary Genetic Analyzer system. We have demonstrated a fully integrated and portable Rotary Genetic Analyzer for detection of the gene expression of influenza A virus, which has 'Sample-in-answer-out' capability including sample pretreatment, rotary amplification, and optical detection. Target gene amplification was real-time monitored using the integrated Rotary Genetic Analyzer system.

• Journal of Korea Water Resources Association
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• v.56 no.2
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• pp.115-124
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• 2023

Currently, as the frequency of extreme weather events increases, the scale of damage increases when extreme weather events occur. This has been providing forecast information by investing a lot of time and resources to predict rainfall from the past. However, this information is difficult for non-experts to understand, and it does not include information on how much damage occurs when extreme weather events occur. Therefore, in this study, a risk matrix based on heavy rain damage rating was presented by using the impact forecasting standard through the creation of a risk matrix presented for the first time in the UK. First, through correlation analysis between rainfall data and damage data, variables necessary for risk matrix creation are selected, and PERCENTILE (25%, 75%, 90%, 95%) and JNBC (Jenks Natural Breaks Classification) techniques suggested in previous studies are used. Therefore, a rating standard according to rainfall and damage was calculated, and two rating standards were synthesized to present one standard. As a result of the analysis, in the case of the number of households affected by the disaster, PERCENTILE showed the highest distribution than JNBC in the Yeongsan River and Seomjin River basins where the most damage occurred, and similar results were shown in the Chungcheong-do area. Looking at the results of rainfall grading, JNBC's grade was higher than PERCENTILE's, and the highest grade was shown especially in Jeolla-do and Chungcheong-do. In addition, when comparing with the current status of heavy rain warnings in the affected area, it can be confirmed that JNBC is similar. In the risk matrix results, it was confirmed that JNBC replicated better than PERCENTILE in Sejong, Daejeon, Chungnam, Chungbuk, Gwangju, Jeonnam, and Jeonbuk regions, which suffered the most damage.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.18 no.12
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• pp.1970-1982
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• 1993

This paper describes an efficient array algorithm for parallel computation of vector-radix two-dimensional (2-D) fast discrete cosine transform (VR-FCT), and its VLSI implementation. By mapping the 2-D VR-FCT onto a 2-D array of processing elements (PEs), the butterfly structure of the VR-FCT can be efficiently importanted with high concurrency and local communication geometry. The proposed array algorithm features architectural modularity, regularity and locality, so that it is very suitable for VLSI realization. Also, no transposition memory is required, which is invitable in the conventional row-column decomposition approach. It has the time complexity of O(N+Nnzp-log2N) for (N*N) 2-D DCT, where Nnzd is the number of non-zero digits in canonic-signed digit(CSD) code, By adopting the CSD arithmetic in circuit desine, the number of addition is reduced by about 30%, as compared to the 2`s complement arithmetic. The computational accuracy analysis for finite wordlength processing is presented. From simulation result, it is estimated that (8*8) 2-D DCT (with Nnzp=4) can be computed in about 0.88 sec at 50 MHz clock frequency, resulting in the throughput rate of about 72 Mega pixels per second.

• The Journal of the Korea Contents Association
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• v.8 no.12
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• pp.37-44
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• 2008

Data entered into RFID tags are used for saving costs and enhancing competitiveness in the development of applications in various industrial areas. RFID readers perform the identification and search of hundreds of objects, which are tags. RFID technology that identifies objects on request of dynamic linking and tracking is composed of application components supporting information infrastructure. Despite their many advantages, existing applications, which do not consider elements related to real.time data communication among remote RFID devices, cannot support connections among heterogeneous devices effectively. As different network devices are installed in applications separately and go through different query analysis processes, there happen the delays of monitoring or errors in data conversion. The present study implements a RFID database handling system in semantic Web environment for integrated management of information extracted from RFID tags regardless of application. Users’ RFID tags are identified by a RFID reader mounted on an application, and the data are sent to the RFID database processing system, and then the process converts the information into a semantic Web language. Data transmitted on the standardized semantic Web base are translated by a smart browser and displayed on the screen. The use of a semantic Web language enables reasoning on meaningful relations and this, in turn, makes it easy to expand the functions by adding modules.

• Journal of Korean society of Dental Hygiene
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• v.11 no.6
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• pp.881-891
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• 2011

Objectives : This study was carried out in order to contribute to preventing dental caries, which is the biggest disease in adolescence and to promoting oral health by implanting a right habit on oral care targeting adolescents, and further to offer basic help to proceeding with making the better health life. Methods : This study carried out questionnaire survey targeting 1,100 students of middle schools where are located in small and medium-sized cities of Gyeongnam from March 7-18, 2011. Statistical processing was performed frequency analysis and cross tabulation, by using SPSSWIN 12.0 program. Results : As for middle school students' oral health education experience, the group with educational experience was indicated to be 52.9% for girl students and 47.1% for boy students(p<.05) in case of gender. Toothbrushing time was indicated to be the highest with 25.6% in 'after having breakfast'. The appearance of toothbrushing after having lunch at school was indicated to be 53.3% for girl students and 26.3% for boy students(p<.001) by gender. The most important reason for toothbrushing accounted for 82.1% in the 1st grade, 71.1% in the 2nd grade, and 67.4% in the 3rd grade depending on school year as for the response as saying of 'aiming to prevent decayed tooth and gum disease.' Thus, the lower school year led to having indicated to be higher in response as saying of brushing teeth for preventing decayed tooth and gum disease(p<.001). As for a toothbrushing method by gender, boy students accounted for 24.2% in response as saying of 'brushing teeth freely', thereby having been indicated to be higher than 15.0% for girl students(p<.001). Conclusions : In order for toothbrushing method to be rightly practiced and habituated continuously, there will be a need of changing adolescents' awareness and of being driven systematically and continuously through oral health education. School oral health education, which can nurture right attitude and habit of oral health care, is thought to be necessarily expanded and executed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.9
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• pp.3927-3932
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• 2014

Background: Epidermal growth factor receptor (EGFR) mutations and echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) define specific molecular subsets of lung adenocarcinomas with distinct clinical features. Our purpose was to analyze clinical features and prognostic value of EGFR gene mutations and the EML4-ALK fusion gene in lung adenocarcinoma. Patients and Methods: EGFR gene mutations and the EML4-ALK fusion gene were detected in 92 lung adenocarcinoma patients in China. Tumor marker levels before first treatment were measured by electrochemiluminescence immunoassay. Results: EGFR mutations were found in 40.2% (37/92) of lung adenocarcinoma patients, being identified at high frequencies in never-smokers (48.3% vs. 26.5% in smokers; P=0.040) and in patients with abnormal serum carcinoembryonic antigen (CEA) levels before the initial treatment (58.3% vs. 28.6%, P=0.004). Multivariate analysis revealed that a higher serum CEA level before the initial treatment was independently associated with EGFR gene mutations (95%CI: 1.476~11.343, P=0.007). We also identified 8 patients who harbored the EML4-ALK fusion gene (8.7%, 8/92). In concordance with previous reports, younger age was a clinical feature for these (P=0.008). Seven of the positive cases were never smokers, and no coexistence with EGFR mutation was discovered. In addition, the frequency of the EML4-ALK fusion gene among patients with a serum CEA concentration below 5ng/ml seemed to be higher than patients with a concentration over 5ng/ml (P=0.021). No significant difference was observed for time to progression and overall survival between EML4-ALK-positive group and EML4-ALK-negative group or between patients with and without an EGFR mutation. Conclusions: The serum CEA level before the initial treatment may be helpful in screening population for EGFR mutations or EML4-ALK fusion gene presence in lung adenocarcinoma patients.

• Journal of The Korean Association For Science Education
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• v.34 no.2
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• pp.147-153
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• 2014

The purpose of this study is to investigate various types of 'flow' that can be observed in the daily lives of science-gifted students, and the correlation between 'flow' and creativity. For two months, we have gathered data on 'flow' in the main activities of science-gifted students through a qualitative application of the Experience Sampling Method (ESM). We then use correlation analysis to determine whether there have been correlations between 'flow' and creativity. Among the four channels, activities involving 'flow' have been the most common (40.4%) in the daily lives of the students. The types of tasks done by the students are, in descending order of frequency, productive activities, social activities, leisure activities, and basic activities. The students have shown the least interest in tasks that do not require specific skills or pose significant challenges; thus the least interest show in basic activities and the most interest has been shown in productive activities. 'Flow' and creativity are significantly correlated at the level of 0.01, which means that the more the students experience 'flow,' the more they express creativity. Based on the results above, we have found that there is a need for the development of science programs or environments, including productivity while at the same time, to reduce uneasiness and patience raising activities, where students can experience more 'flow' in daily life.

• Journal of Wetlands Research
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• v.17 no.3
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• pp.251-263
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• 2015

This study suggested a novel approach of estimating the optimal probability density function (OPDF) of the annual maximum rainfall time series (AMRT) combining the L-moment ratio diagram and the geographical information system. This study also reported several interesting geographical characteristics of the AMRT in Korea. To achieve this purpose, this study determined the OPDF of the AMRT with the duration of 1-, 3-, 6-, 12-, and 24-hours using the method of L-moment ratio diagram for each of the 67 rain gages in Korea. Then, a map with the Thiessen polygons of the 67 rain gages colored differently according the different type of the OPDF, was produced to analyze the spatial trend of the OPDF. In addition, this study produced the color maps which show the fitness of a given probability density function to represent the AMRT. The study found that (1) both L-skewness and L-kurtosis of the AMRT have clear geographical trends, which means that the extreme rainfall events are highly influenced by geography; (2) the impact of the altitude on these two rainfall statistics is greater for the mountaneous region than for the non-mountaneous region. In the mountaneous region, the areas with higher altitude are more likely to experience the less-frequent and strong rainfall events than the areas with lower altitude; (3) The most representative OPDFs of Korea except for the Southern edge are Generalized Extreme Value distribution and the Generalized Logistic distribution. The AMRT of southern edge of Korea was best represented by the Generalized Pareto distribution.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.7
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• pp.485-494
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• 2013

An efficient extraction method was developed for the analysis of 16 perfluorinated compounds (PFCs) in fish samples. We compared the recoveries from the Ion-Pairing Extraction (IPE), Liquid-Liquid Extraction (LLE), Solid-Phase Extraction (SPE), IPE + SPE method with varying the injection time of the internal standard. As a result, IPE method with the internal standard before extraction was evaluated as the most effective pretreatment method. The RPM (Revolution Per Munite) and pH in IPE-before method were additionally adjusted and the more efficient pretreatment method was established. The total 33 fish samples including liver and gut samples were collected from Korean markets and analyzed PFCs with developed pretreatment method of this study. Total 16 PFC levels in fish samples ranged from ND to 1.67 ng/g with 100% detection frequency. The average PFCs concentrations of muscle, liver and gut samples from fish were compared and showed the following trend: liver (17.8 ng/g) > gut (13.3 ng/g) > muscle (1.67 ng/g). The PFC levels in fish samples were similar or lower than other available previous results of foreign studies.