• Journal of Trauma and Injury
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• v.35 no.1
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• pp.25-33
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• 2022

Purpose: The scoring system for traumatic liver injury (SSTLI) was developed in 2015 to predict mortality in patients with polytraumatic liver injury. This study aimed to validate the SSTLI as a prognostic factor in patients with polytrauma and liver injury through a generalized estimating equation analysis. Methods: The medical records of 521 patients with traumatic liver injury from January 2015 to December 2019 were reviewed. The primary outcome variable was in-hospital mortality. All the risk factors were analyzed using multivariate logistic regression analysis. The SSTLI has five clinical measures (age, Injury Severity Score, serum total bilirubin level, prothrombin time, and creatinine level) chosen based on their predictive power. Each measure is scored as 0-1 (age and Injury Severity Score) or 0-3 (serum total bilirubin level, prothrombin time, and creatinine level). The SSTLI score corresponds to the total points for each item (0-11 points). Results: The areas under the curve of the SSTLI to predict mortality on post-traumatic days 0, 1, 3, and 5 were 0.736, 0.783, 0.830, and 0.824, respectively. A very good to excellent positive correlation was observed between the probability of mortality and the SSTLI score (γ=0.997, P<0.001). A value of 5 points was used as the threshold to distinguish low-risk (<5) from high-risk (≥5) patients. Multivariate analysis using the generalized estimating equation in the logistic regression model indicated that the SSTLI score was an independent predictor of mortality (odds ratio, 1.027; 95% confidence interval, 1.018-1.036; P<0.001). Conclusions: The SSTLI was verified to predict mortality in patients with polytrauma and liver injury. A score of ≥5 on the SSTLI indicated a high-risk of post-traumatic mortality.

• Transactions of the Korean Society of Automotive Engineers
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• v.10 no.1
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• pp.143-152
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• 2002

European side impact analysis of an electric vehicle was done using the robust design method. In order to minimize VC as well as rib deflection, the injury response table which consists of rib deflection and VC response table has been introduced. The sensitivities and interactions are almost the same when it was compared with those of rib deflection and VC response table. Using internal energy of the factors, the starting time of dummy rib deflection and the contact average velocity, the internal energy and time-velocity response table were introduced. It is shown that the results of the new response tables have the similar characteristics to those of the Injury response table. It is suggested that the internal energy and time-velocity response table should be utilized to minimize injuries.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.45 no.5
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• pp.233-240
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• 2019

Trigeminal nerve injury as a consequence of lower third molar surgery is a notorious complication and may affect the patient in long term. Inferior alveolar nerve (IAN) and lingual nerve (LN) injury result in different degree of neurosensory deficit and also other neurological symptoms. The long term effects may include persistent sensory loss, chronic pain and depression. It is crucial to understand the pathophysiology of the nerve injury from lower third molar surgery. Surgery remains the most promising treatment in moderate-to-severe nerve injuries. There are limitations in the current treatment methods and full recovery is not commonly achievable. It is better to prevent nerve injury than to treat with unpredictable results. Coronectomy has been proved to be effective in reducing IAN injury and carries minimal long-term morbidity. New technologies, like the roles of erythropoietin and stem cell therapy, are being investigated for neuroprotection and neural regeneration. Breakthroughs in basic and translational research are required to improve the clinical outcomes of the current treatment modalities of third molar surgery-related nerve injury.

• Journal of Korean Neurosurgical Society
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• v.46 no.3
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• pp.205-209
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• 2009

Objective : This study was conducted to investigate the correlation between the degrees of injury on brain magnetic resonance imaging (MRI) and the time interval to recovery of consciousness in patients with diffuse axonal injury. Methods : From January 2004 to December 2008, 25 patients with diffuse axonal injury were treated at our hospital. We retrospectively investigated the patients' medical records and radiological findings. We divided the patients into three groups according to the grade of MRI finding : grade I, small scattered lesions on the white matter of the cerebral hemisphere; grade II, focal lesions on the corpus callosum; and grade III, additional focal lesions on the brain stem. Result : Seven patients belonged to the grade I group; 10 to the grade II group; and 8 to the grade III group. The mean Glasgow Coma Scale (GCS) score of all patients at the time of admission was 7.28. Recovery of consciousness was observed in 23 of the 25 patients; the remaining two patients never regained consciousness. The time interval to recovery of consciousness (awake status) ranged from 1 day to 125 days (mean 22.1 days) : grade I group patients, within approximately 1 week (mean 3.7 days); grade II group patients, within approximately 2 weeks (mean 12.5 days); and grade III group patients, within approximately 2 months (mean 59.5 days). Conclusion : Our study results suggest a correlation between the mean time interval to recovery of consciousness in patients with diffuse axonal injuries and the degrees of brain injuries seen on MRI. Patients with grade I and II diffuse axonal injuries recovered consciousness within 2 weeks, while patients with grade III injuries required approximately 2 months.

• Journal of Trauma and Injury
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• v.30 no.3
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• pp.75-79
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• 2017

Purpose: Although trauma is the most common cause of death under age 18, Korean national pediatric trauma data has lack of clinical data. This study is to prepare manpower resources, equipment, and make a correct policy decision on pediatric trauma victims Methods: The study enrolled 528 patients under age 16 with traumatic injury visited Wonju Severance Christian Hostpital Trauma Center, from February 12, 2015 to December 31, 2016. We analyzed the distribution of gender, age, place and time of the accident, injury mechanism, injury severity, and injured organ by medical record. Results: The major injury mechanisms were blunt injury in 485 (91.90%), penetrating injury in 27 (5.10%), burn in 13 (2.50%), near drowning in 2 (0.40%), and foreign body ingestion in 1 (0.20%). Ninety-seven (18.4%) patients were injured at home and 67 (12.7%) patients were injured at school. The overall mortality rate was 1.13% (n=6). 5 mortalities were related to automobile accident and one was fall down. Mean Injury Severity Score (ISS) was 4 (2, 8). No statistical significance was observed in the mean ISS between each age group. The peak time of accident occurrence was between 16 and 17 o'clock. The mean ISS was higher in blunt injury group than penetrating injury with statistical significance ($6.50{\pm}7.60$ vs. $3.00{\pm}8.10$; p<0.05). The most common injury site was upper extremity. Mean ISS was highest in thorax injury. However, mean ISS of thorax injury was higher with statistical significance only compared with face, neck and upper extremity injury. Conclusions: We reported our pediatric trauma patients data of our hospital level I trauma center, which is the only one level I trauma center of Gangwon Province. These data is useful to prevent and prepare for pediatric trauma.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.472-482
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• 2016

The purpose of this study was to determine if a geriatric injury would have a statistically significant relationship with the spatial safety within a specific region. To achieve the objectives of this study, an independent sample t-test and One-way ANOVA were performed to verify difference in mean value of regional safety grade, depending on the injury intentionality, injury location, activities at the time of injury, and injury mechanism, in 6,572 geriatric injury patients by combining the National Hospital Discharge Patients Injury Survey data and regional safety index data. The results of statistical validation suggested that there was no difference in the mean value of regional safety grade by sub-group with respect to the injury intentionality. However, a statistically significant difference was observed in terms of the mean value of regional safety grade in each sub-group with regard to the injury location, activities at the time of injury, and injury mechanism in connection with some areas of the regional safety index. Based on the results of such analysis, we derived and presented 3 implications related to policies and practice for the prevention of geriatric injury and a reduction of its occurrence rate in light of spatial safety after a discussion of the results through a comparison with previous studies that examined individual areas.

• Journal of Chest Surgery
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• v.25 no.1
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• pp.66-72
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• 1992

From March 1986 to March 1991, 29 patients were operated due to cardiac tamponade at the Department of Thoracic and Cardiovascular Surgery, Masan Koryo General Hospital. Among them, 19cases were traumatic origin and 10 were Non traumatic origin. A] Traumatic cardiac tamponade Out of 19 cases, 12 cases were resulted from penetrating injury and 7 cases from trauma. Average time interval from arrival to operation was 91 minutes[15min.~8.5hr.] in penetrating injury group. On the other hand, average time of in cases of blunt trauma was more than 3hours because of the difficulties in diagnosis. Four deaths occured in 19 cases [mortality rate: 21.1%] 3 in blunt trauma group[42.9%] and 1 in penetrating group[8.3%]. In view of our experience, the prognosis was closely correlated with injury mode, initial vital sign and mental status. There was no close correlation between prognosis and cardiac injury site. B] Non traumatic cardiac tamponade The etiologies were malignancy[4], non-spesific pericarditis[3], tuberculosis[1], pyogenic[1] and cardiomyopathy[1]. All of the cases in which performed tube pericardiostomy were the cases that showed no response to conservative treatment and repeat per-icardiocentesis. There was one posoperative death.

• Journal of Korean Society for Atmospheric Environment
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• v.2 no.2
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• pp.1-8
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• 1986

To obtain the guidance of plants sensitivity or resistance to $SO_2$ gas, 16 species, 25 varieties of plants were exposed to 0, 0.2, 0.4, 0.7 and 1.5 ppm of $SO_2$ gas in controlled environmental chamber and the visible injury on the plants was observed. Plant sensitivity and/or resistance rankings at each guidance appeared different, based on first injured time, injury degree, and injury index. Only 10 varieties of plant are equal in the ranking at different base. It is concluded that recommended guidance for sensitivity and resistance of plants to $SO_2$ gas are the first injured time and the injury degree, respectively.

• Korean Journal of Transplantation
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• v.28 no.3
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• pp.135-143
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• 2014

Background: Kidney injury molecule-1 (KIM-1) is known as a good ancillary marker of acute kidney injury (AKI) and its expression has also been observed in acute rejection and chronic graft dysfunction. We tested usefulness of KIM-1 as an indicator of acute and chronic renal graft injury by correlating KIM-1 expression with renal graft function and histology. Methods: A total of 133 zero-time biopsies and 42 follow-up biopsies obtained within 1 year posttransplantation were selected. Renal tubular KIM-1 staining was graded semiquantitatively from 0 to 3 and the extent of staining was expressed as the ratio of KIM-1 positive/CD10 positive proximal tubules using Image J program. Results: KIM-1 was positive in 39.8% of zero-time biopsies. KIM-1 positive cases were predominantly male and had received grafts from donors with older age, deceased donors, and poor renal function at the time of donation, compared with KIM-1 negative cases. KIM-1 expression showed correlation with delayed graft function and acute tubular necrosis. In comparison of KIM-1 expression between stable grafts (n=23) and grafts with dysfunction (n=19) at the time of repeated biopsy, the intensity/extent of KIM-1 staining and renal histology at zero-time did not differ significantly between the two groups. Histologically, KIM-1 expression was significantly increased with both acute and chronic changes of glomeruli, tubules and interstitium, peritubular capillaritis, and arteriolar hyalinosis. Conclusions: KIM-1 can be used as an ancillary marker of AKI and a nonspecific indicator of acute inflammation and tubulointerstitial fibrosis. However, KIM-1 expression at zero-time is not suitable for prediction of long-term graft dysfunction.

• Journal of Environmental Health Sciences
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• v.49 no.3
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• pp.149-158
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• 2023

Background: Injury is one of the major health problems in South Korea. Few studies have evaluated both intentional and unintentional injury when investigating the association between exposure to air pollutants and injury. Objectives: We aimed to explore the association between short-term exposure to ambient air pollution and years of life lost (YLLs) due to injury. Methods: Data on daily YLLs for 2002~2019 were obtained from the the Death Statistics Database of the Korean National Statistical Office. This study estimated short-term exposure to particulate matter with an aerodynamic diameter of <10 ㎛ (PM₁₀), particulate matter with an aerodynamic diameter of <2.5 ㎛ (PM_2.5), sulfur dioxide (SO₂), nitrogen dioxide (NO₂), carbon monoxide (CO), and ozone (O₃). This time series study was conducted using a generalized additive model (GAM) assuming a Gaussian distribution. We also evaluated a delayed effect of ambient air pollution by constructing a lag structure up to seven days. The best-fitting lag was selected based on smallest generalized cross validation (GCV) value. To explore effect modification by intentionality of injury (i.e., intentional injury [self-harm, assault] and unintentional injury), we conducted stratified subgroup analyses. Additionally, we stratified unintentional injury by mechanism (traffic accident, fall, etc.). Results: During the study period, the average daily YLLs due to injury was 307.5 years. In the intentional injury, YLLs due to self-harm and assault showed positive association with air pollutants. In the unintentional injury, YLLs due to fall, electric current, fire and poisoning showed positive association with air pollutants, whereas YLLs due to traffic accident, mechanical force and drowning/submersion showed negative associations with air pollutants. Conclusions: Injury is recognized as preventable, and effective strategies to create a safe society are important. Therefore, we need to establish strategies to prevent injury and consider air pollutants in this regard.