• Title/Summary/Keyword: Time Capsule

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Development of Shattering Machine for Sesame (III) - Fabrication and Evaluation of the Final Machine - (참깨 탈립 작업기계 개발에 관한 연구(III) - 최종기 제작 및 평가 -)

  • Lee, Jong-Su;Kim, Ki-Bok
    • Journal of Biosystems Engineering
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    • v.34 no.6
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    • pp.425-433
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    • 2009
  • The developed final shattering machine for labor-saving mechanization of shattering of sesame consisted of input part, shattering part, re-shattering part for unshattered pod and pneumatic sorter. The bundle of sesame was held as upside down and fed into the machine continuously. Then, the fed bundle of sesame was shattered by side shock and agitation. The performance of shattering for the sun dried bundle of sesame of conventional manual work and final shattering machine was compared. Since the shattering ratio measured by the final machine was 97.2% at the first operation, in case of fully dried sesame by drying stand, the harvest of sesame can be completed by only one time shattering operation. The work hour per area of 10 a for the mechanical work and the manual work were 0.3 hour and 13.9 hour, respectively. The total shattering ratio of the final machine with vertical feedings of bundle of sesames was 97.2%.

Superimposed Propionibacterium Acnes Subdural Empyema in a Patient with Chronic Subdural Hematoma

  • Kim, Jong-Hun;Lee, Chul-Hee;Hwang, Soo-Hyun;Kang, Dong-Ho
    • Journal of Korean Neurosurgical Society
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    • v.45 no.1
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    • pp.53-56
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    • 2009
  • The authors present a case of subdural empyema in a macrocephalic patient. A 23-year-old male was admitted due to headache and fever. One month ago, he had mild head injury by his coworkers. Physical examination showed a macrocephaly and laboratory findings suggested purulent meningitis. Neuroimaging studies revealed a huge size of epidural space-occupying lesion. Under the impression of epidural abscess, operation was performed. Eventually, the lesion was located at subdural space and was proven to be subdural empyema. Later, histological examination of the specimen obtained by surgery demonstrated finings consistent with the capsule of the chronic subdural hematoma. Two weeks after operation, Propionibacterium acnes was isolated. The intravenous antibiotics were used for total of eight weeks under monitoring of the serum level of the C-reactive protein. Follow-up brain computed tomography (CT) scan showed the presence of significant amount of remaining subdural lesion. However, he has complained of minimal discomfort. It is suggested that the subdural empyema occurred with preexisting chronic subdural hematoma after head injury about one month prior to admission and it took a long time to treat Propionibacterium acnes subdural empyema with systemic antibiotics, at least over eight weeks.

(An) experimental study on the development of lightweight concrete using the PCM (PCM 혼입 경량기포콘크리트 패널 개발을 위한 기초적 연구)

  • Lim, Myung Kwan;Enkhbold, Odontuya;Kim, Young Ho;Choi, Dong Uk
    • KIEAE Journal
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    • v.14 no.4
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    • pp.133-138
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    • 2014
  • The present study was carried out to assess the basic material properties and thermal behavior of light-weight foamed concrete panel mixed with PCM (Phase Changing Material). To do so, this study fabricated light-weight foamed concrete (1.0kg/m3) in pre-foaming method and mixed it with PCM micro capsule of 1-dodecanol and melamine to examine its physical and thermal properties. The results confirmed strength reinforcement effect by proper replacement ratio of fly-ash, which is an industrial by-product, and PCM. In addition, it found out that PCM-mixed light-weight foamed concrete had time delay and temperature reduction effect within the range of PCM phase transition according to the rise of outdoor temperature. It was also observed that the insulation performance of PCM-mixed light-weight foamed concrete was more dependent upon thickness than PCM replacement ratio.

Enhanced Bioavailability of Itraconazole in Liquid Preparation (난용성 항진균제 이트라코나졸의 액상제제화에 의한 생체이용율 개선)

  • Hwang, Woo-Sin;Kwon, Kwang-Il;Bang, Kyu-Ho
    • YAKHAK HOEJI
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    • v.44 no.6
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    • pp.528-533
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    • 2000
  • This study was to develop an effective itraconazole liquid preparation which exhibits an enhanced bioavailability. The solubility of itraconazole was increased (72-fold) in itraconazole liquid preparation as compared with itraconazole powder. The dissolution rate of itraconazole was higher for itraconazole liquid preparation filled into a hard gelatin capsule with 90% release within 20 min as compared to 55% for $Sporanox^{\circledR}$capsules. The oral absorption of itraconazole liquid preparation and $Sporanox^{\circledR}$tablets were studied in the rat. The area under the concentration-time curve $(AUC_{0-24hr})$ of itraconazole liquid preparation ($90.25\;{\pm}\;8.36\;{\mu}g{\cdot}hr/ml$) increased by 6.2 times compared to that of Sporanox tablets ($14.58\;{\pm}\;1.26\;{\mu}g{\cdot}hr/ml$) after oral administration of itraconazole 15 mg/rat each. $C_{max}$ also increased to $6.87\;{\pm}\;1.15\;{\mu}g/ml$ after administration of liquid preparation $1.58\;{\pm}\;0.16\;{\mu}g/ml$ of $Sporanox^{\circledR}$tablets. These results indicate that in vivo bioavailability of itraconazole liquid preparation was significantly enhanced as compared with $Sporanox^{\circledR}$tablets.

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Ultrasonographic Evaluation of Surgically Induced Cranial Cruciate Ligament Rupture in the Dog (개에서 전십자 인대 단열의 초음파적 평가)

  • 성윤상;엄기동;장광호
    • Journal of Veterinary Clinics
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    • v.20 no.2
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    • pp.229-232
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    • 2003
  • Ultrasonographic examination of the stifle joint four clinically and radiographically normal adult dogs was performed before and after inducing the cranial cruciate ligament (CrCL) rupture of the bilateral stifle surgically. At Pre- or post-surgery, the hyperechoic patella ligament and the echogenic infrapatella fat interfered the visualization of the CrCL by the plain scanning method. However when the stifle joint was imaged by the scanning method injecting normal saline within the joint capsule, the hyperechogenic ligament was visualized by the separation of the infrapatella fat and the CrCL and the contrast effect of anechoic saline. When the stifle joint was imaged by the real time scanning method after the induction of the surgical rupture, fluttering of the ligament and anechoic area between the bone and the CrCL was identified due to the lack of tonicity and continuity of the ligament. Enlargement of the ligament because of its increased diameter as well as fluttering of the CrCL and the increased joint space's thickness was visualized. Consequently, confirming fluttering of the CrCL, increased ligament diameter and anechoic region between the CrCL and the bone, ultrasonographic examination is a valuable diagnostic tool as well as cranial drawer test and radiographic examination.

Experimental Hepatic Capillariasis in Dogs (개의 실험적 간모세선충증)

  • 곽동미;권오덕
    • Journal of Veterinary Clinics
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    • v.21 no.3
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    • pp.243-247
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    • 2004
  • This studies was carried out to investigate a process of formation for the granulomatous lesions in the liver and the haematological variation with the lapse of time after infection of Capillaria hepatica in dogs. Twelve crossbred puppies, about 3 months of age and 2-3 kg of body weight, were administered with 2,000 Capillaria hepatica infective eggs. Every four puppies was sacrificed on 1 week, 3 weeks and 5 weeks after infection, respectively. Although no marked clinical sign was noticed, total leukocyte values were increased peak on 1 week, and then reduced gradually on 3 weeks and 5 weeks after infection. Absolute differential counts of neutrophils and lymphocytes were significantly increased on 1, 3 and 5 weeks after infection. Absolute differential counts of monocytes and eosinophils were trend to increase during the experimental periods. On grossly findings, liver congestions were observed in all infected puppies, and a few white specks were scattered under liver capsule in one puppy on 3 weeks and two puppies on 5 weeks after infection. On microscopic findings, many fresh larvae were observed in the liver tissues in one puppy on 1 week after infection. A worm was decayed and only a portion of cuticle was shown in one puppy on 3 weeks after infection. Around the central necrotic material, the layers of thick macrophages with a few giant cells and lymphocytes with fibrous connective tissues were consisted the granulomatous lesions on 5 weeks after infection.

The Story of Serratia Marcescens: Pathologic Risk Factors in Breast Implant Surgery

  • Yao, Caroline A.;Wang, Diana;Kulber, David A.
    • Archives of Plastic Surgery
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    • v.41 no.4
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    • pp.414-417
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    • 2014
  • Serratia marcescens (S. marcescens) emerged as an opportunist in the setting of immunodeficiency in the 1970s, when serious infections occurred in San Francisco hospitals after USA. Navy experiments had aerosolized the bacteria to study biologic warfare. We investigate the risks of S. marcescens in San Franciscans who undergo mastectomy with implant reconstruction. From 2007 to 2011, the senior author took breast capsule cultures for all patients at the time of tissue expander exchange/explant. Of the 142 women who had reconstruction, 23 had positive cultures. Only the two patients who were positive for S. marcescens developed clinical infections that required explantation. Both had postoperative chemotherapy with transient neutropenia, and both had close ties to San Francisco. Clinical signs of infection emerged for both patients months after initial surgery, despite having previously well healed incisions. Other patients were culture positive for Pseudomonas, Proteus, Enterococcus and MRSA and did not develop require explant. While the link between San Francisco and S. marcescens is controversial, a patient's geography is a simple screening tool when considering postoperative risks, especially in the immunocompromised. Closer monitoring for neutropenia during chemotherapy, and a lower threshold to administer S. marcescens targeted antibiotics may be warranted in these patients.

Effect of Pressurization and Cooling Rate on Dissolution of a Stationary Supercooled Aqueous Solution (정지상태 수용액에서 가압과 냉각속도가 과냉각해소에 미치는 영향)

  • Kim, Byung-Seon;Peck, Jong-Hyun;Hong, Hi-Ki;Kang, Chae-Dong
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.12
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    • pp.850-856
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    • 2007
  • In a supercooled or capsule type ice storage system, aqueous solution (or water) may have trouble with non-uniform dissolution though the system contributes to the simplicity of system and ecological improvement. The non-uniform dissolution increases the instability of the system because it may cause an ice blockage in pipe or cooling part. In order to observe the supercooled state, a cooling experiment was performed with pressurization to an ethylene glycol(EG) 3 mass% solution in stationary state. Also, the effect of the pressurization from 101 to 505 kPa to the dissolution of supercooled aqueous solution was measured with the dissolution time of the supercooled aqueous solution at a fixed cooling rate of brine. At results, the dissolution of supercooled point decreased as the pressure of the aqueous solution in the vessel increased. Moreover, the dissolution point increased as the heat flux for cooling increased.

Bioabaibility of Oxytetracycline and Erythromycin stearate (Oxytetracycline과 Erythromycin Stearate의 생체유용성 검토)

  • Lim J.K.;Chung M.H.;Shin S.G.;Cha I.J.
    • The Korean Journal of Pharmacology
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    • v.13 no.1 s.21
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    • pp.1-6
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    • 1977
  • The physicochemical equivalencies of drugs are not usually correlate to the generic equivalencies of drugs and the generic equivalencies of drugs produced by different manufacturers or different formulations are being called in question frequently. The bioabailability of two formulations of oxytetracycline and erythromycin stearate were performed in healthy human volunteers. At the same time, the disintegration testes were performed with randomly sampled materials in question. For the biological evaluation of new oxytetracycline formulation; tablet(250mg), two-way cross over study in 10 healthy young volunteers was performed using oxytetracycline capsule (250mg) as reference, Erythromycin stearate (250mg) tablets and capsules produced by different manufacturers were compared in a two-way cross over study in 12 subjects with same manner of oxytetracyclines. oxytetracycline tablets showed somewhat slow disintegration rate, but appeared not statistical differences in serum concentrations from the reference, up to six hours after ingestion. Erythromycin stearate capsules disintegrated more rapidly than enteric coated tablets. Serum concentrations of capsules were more variable and markedly lower (P<.005 after 2hrs) than the enteric coated tablets. Rapid disintegration of capsules may result in destruction of active chemicals owing to the interaction with gastric acid and the above factor may contribute mainly to the low serum level after ingestion of capsules.

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CHARACTERISTICS OF A NEW PNEUMATIC TRANSFER SYSTEM FOR A NEUTRON ACTIVATION ANALYSIS AT THE HANARO RESEARCH REACTOR

  • Chung, Yong-Sam;Kim, Sun-Ha;Moon, Jong-Hwa;Baek, Sung-Yeol;Kim, Hark-Rho;Kim, Young-Jin
    • Nuclear Engineering and Technology
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    • v.41 no.6
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    • pp.813-820
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    • 2009
  • A rapid pneumatic transfer system (PTS) for an instrumental neutron activation analysis (INAA) is developed as an automatic irradiation facility involving the measurement of a short half-life nuclide and a delayed neutron counting system. Three new PTS designs with improved functions were constructed at the HANARO research reactor in 2006. The new system is composed of a manual system and an automatic system for both an INAA and a delayed neutron activation analysis (DNAA). The design and basic conception of a modified PTS are described, and the functions of system operation and control, radiation protection and emissions of radioactive gas are improved. In addition, a form of capsule transportation of these systems is tested. The experimental results pertaining to the irradiation characteristics with variation of the neutron flux and the temperature of the irradiation position with the irradiation time are presented, as is an analysis of the reference material for analytical quality control and uncertainty assessments.