• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.3
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• pp.1670-1683
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• 2017

Mitotic event recognition is a crucial and challenging task in biomedical applications. In this paper, we introduce the slow feature analysis and propose a fully-automated mitotic event recognition method for cell populations imaged with time-lapse phase contrast microscopy. The method includes three steps. First, a candidate sequence extraction method is utilized to exclude most of the sequences not containing mitosis. Next, slow feature is learned from the candidate sequences using slow feature analysis. Finally, a hidden conditional random field (HCRF) model is applied for the classification of the sequences. We use a supervised SFA learning strategy to learn the slow feature function because the strategy brings image content and discriminative information together to get a better encoding. Besides, the HCRF model is more suitable to describe the temporal structure of image sequences than nonsequential SVM approaches. In our experiment, the proposed recognition method achieved 0.93 area under curve (AUC) and 91% accuracy on a very challenging phase contrast microscopy dataset named C2C12.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4097-4100
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• 2012

Background/Aims: Diabetes mellitus (DM) is widely considered to be associated with risk of cancer, but studies investigating the association between DM and prostate cancer in Asian countries have reported inconsistent findings. We examined this association by conducting a detailed meta-analysis of studies published on the subject. Methods: Cohort or case-control studies were identified by searching Pubmed, Embase and Wanfang databases through May 30, 2012. Pooled relative risk (RR) with its corresponding 95% confidence interval (95% CI) were calculated using the random-effects model. Subgroup analyses were performed by the study type. Results: Finally, we identified 7 studies (four cohort studies and three case-control studies) with a total of 1,751,274 subjects from Asians. DM was associated with an increased risk of prostate cancer in Asians (unadjusted RR= 2.82, 95% CI 1.73.4.58, P < 0.001; adjusted RR= 1.31, 95% CI 1.12.1.54, P = 0.001). Subgroup analyses by study design further confirmed an obvious association. Conclusion: Findings from this meta-analysis strongly support that diabetes is associated with an increased risk of prostate cancer in Asians.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.3
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• pp.1243-1263
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• 2018

The two-stage linear discrimination analysis (TSLDA) is a feature extraction technique to solve the small size sample problem in the field of image recognition. The TSLDA has retained all subspace information of the between-class scatter and within-class scatter. However, the feature information in the four subspaces may not be entirely beneficial for classification, and the regularization procedure for eliminating singular metrics in TSLDA has higher time complexity. In order to address these drawbacks, this paper proposes an improved two-stage linear discriminant analysis (Improved TSLDA). The Improved TSLDA proposes a selection and compression method to extract superior feature information from the four subspaces to constitute optimal projection space, where it defines a single Fisher criterion to measure the importance of single feature vector. Meanwhile, Improved TSLDA also applies an approximation matrix method to eliminate the singular matrices and reduce its time complexity. This paper presents comparative experiments on five face databases and one handwritten digit database to validate the effectiveness of the Improved TSLDA.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.7
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• pp.3338-3355
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• 2018

Images acquired by Large Aperture Static Imaging Spectrometer (LASIS) exhibit obvious interference stripes, which are vertical and stationary due to the special imaging principle of interference hyperspectral image (IHI) data. As the special characteristics above will seriously affect the intrinsic structure and sparsity of IHI, decomposition of IHI has drawn considerable attentions of many scientists and lots of efforts have been made. Although some decomposition methods for interference hyperspectral data have been proposed to solve the above problem of interference stripes, too many times of iteration are necessary to get an optimal solution, which will severely affect the efficiency of application. A novel algorithm for decomposition of interference hyperspectral images based on split Bregman iteration is proposed in this paper, compared with other decomposition methods, numerical experiments have proved that the proposed method will be much more efficient and can reduce the times of iteration significantly.

• International Journal of Concrete Structures and Materials
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• v.11 no.2
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• pp.403-413
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• 2017

Residual axial capacity from numerical analysis was widely used as a critical indicator for damage assessment of reinforced concrete (RC) columns subjected to blast loads. However, the convergence of the numerical result was generally based on the displacement response, which might not necessarily generate the correct post-blast results in case that the strain softening behavior of concrete was considered. In this paper, two widely used concrete models are adopted for post-blast analysis of a RC column under blast loading, while the calculated results show a pathological mesh size dependence even though the displacement response is converged. As a consequence, a nonlocal integral formulation is implemented in a concrete damage model to ensure mesh size independent objectivity of the local and global responses. Two numerical examples, one to a RC column with strain softening response and the other one to a RC column with post-blast response, are conducted by the nonlocal damage model, and the results indicate that both the two cases obtain objective response in the post-peak stage.

• Journal of Power Electronics
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• v.13 no.1
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• pp.70-76
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• 2013

For high power high step-down dc-dc conversion applications, conventional three-level dc-dc converters are subject to extreme duty cycles or increased volume and cost due to the use of transformers. In this paper, a transformerless three-level dc-dc buck converter with a high step-down conversion ratio is proposed. The converter comprises two asymmetrical half bridges, which are of the neutral point clamped structures. Therefore, the output pulse voltage of the converter can be obtained in terms of the voltage difference between the two half bridges. In order to realize harmonious switching of the converter, a modulation strategy with capacitor voltages self balance is presented. According to the deduced output dc voltage function, transformerless operation without extreme duty cycles can be implemented. Experimental results from a 1kW prototype verify the validity of the proposed converter. It is suitable for ship electric power distribution systems.

• Membrane and Water Treatment
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• v.3 no.1
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• pp.35-49
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• 2012

In membrane processes, various agents are used to enhance, protect, and recover membrane performance. Applying these agents in membrane modification could potentially be considered as a simple method to improve membrane performance without additional process. Citric acid (CI) and sodium bisulfite (SB) are two chemicals that are widely used in membrane feed water pretreatment and cleaning processes. In this work, preadsorptions of CI and SB were developed as simple methods for polysulfone ultrafiltration membrane modification. It was found that hydrogen bonding and Van Der Waals attraction could be responsible for the adsorptions of CI and SB onto membranes, respectively. After modification with CI or SB, the membrane surfaces became more hydrophilic. Membrane permeability improved when modified by SB while decreased a little when modified by CI. The modified membranes had an increase in PEG and BSA rejections and better antifouling properties with higher flux recovery ratios during filtration of a complex pharmaceutical wastewater. Moreover, membrane chlorine tolerance was elevated after modification with either agent, as shown by the mechanical property measurements.

• Structural Engineering and Mechanics
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• v.62 no.4
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• pp.455-464
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• 2017

Rayleigh damping model is recommended in the recently developed Performance-Based Earthquake Engineering (PBEE) methodology, but this methodology does not provide sufficient information due to the complexity of the damping mechanism. Furthermore, each Rayleigh-type damping model may have its individual limitations. In this study, Rayleigh-type damping models that are used widely in engineering practice are discussed. The seismic performance of a large-span single-layer latticed dome subjected to earthquake ground motions is investigated using different Rayleigh damping models. Herein a simulation technique is developed considering low cycle fatigue (LCF) in steel material. In the simulation technique, Ramberg-Osgood steel material model with the low cycle fatigue effect is used to simulate the non-uniformly distributed material damping and low cycle fatigue damage in the structure. Subsequently, the damping forces of the structure generated by different damping models are compared and discussed; the effects of the damping ratio and roof load on the damping forces are evaluated. Finally, the low cycle fatigue damage values in sections of members are given using these damping models. Through a comparative analysis, an appropriate Rayleigh-type damping model used for a large span single-layer latticed dome subjected to earthquake ground motions is determined in terms of the existing damping models.

• Steel and Composite Structures
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• v.20 no.3
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• pp.487-500
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• 2016

In order to investigate the flexural bearing capacity of panel zone of diaphragm-through joint between concrete filled square steel tubular column and steel beam, four specimens were tested under static tension loads to study the mechanical properties and bearing capacity of diaphragm-through joints with a failure mode of panel zone. Finite element models of these specimens were developed to simulate the test and compare the predicted failure modes, load-displacement curves and bearing capacities with the experimentally observed. It was found that the tensile load from the steel beam flange is mainly shared by the square steel tube and the diaphragm. The diaphragm plastic zone appears along the cross-section lines enclosed by the square steel tube and the influence of steel beam web on the plastic zone of the steel tube is significant and cannot be neglected. Computational models of yield lines on square steel tube and diaphragm are established based on the distribution pattern of the plastic zone, and an analytical method for the evaluation of the bearing capacity of the joint is proposed. The theoretical results and the experimental data are compared and found in good agreement.

• Steel and Composite Structures
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• v.25 no.1
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• pp.57-65
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• 2017

The fatigue fracture of studs is the main reason for failure of composite beams based on massive engineering practices. Hence, studying the laws of cracks initiation and propagation are of great directive significance. eXtended Finite Element Method (XFEM) is an effective method in solving moving discontinuous problems in recent years. This paper extends our recent work on the fatigue damage analysis of stud shear connectors in the steel and crumble rubber concrete (RRFC) composite beams based on XFEM. The process of crack initiation to failure of the stud is simulated and an effective calculation criteria for the fatigue life of the composite beams is put forward. After the reliability of the numerical analysis is verified based on tests results, the extensive parametric study is conducted concerning effects of different rubber contents, shear connection degrees and the stress amplitudes. Results show that with the increasing rubber contents and shear connection degrees, the fatigue lives of composite beams increase obviously. Furthermore, the relationship between the fatigue life of the stud at the edge of the shear span and the whole composite beams is studied. Finally, the S-N curves of the single stud and the whole composite beams are put forward based on XFEM.