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Studies on Feline Electroacupuncture Anesthesia (고양이의 전침마취에 관한 연구)

  • 김인봉;김무강;조성환;김덕환;유명조;이성호;이성옥;권건오;김명철
    • Journal of Veterinary Clinics
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    • v.16 no.2
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    • pp.413-416
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    • 1999
  • To establish feline electroacupuncture anesthesia, 5 cats (mixed, 1 month old, 0.4~0.5 kg, female) were examined in the present study. The acupoints used for feline electroacupuncture anesthesia were Tian-ping and Bai-hui. After perpendicular insertion of needle to Tian-ping and Bai-hui, respectively, positive electrode was connected at Tian-ping and negative electrode was connected at Bai-hui, respectively, Electric condition was 3 V and 30 Hz. To examine the effect of electroacupuncture anesthesia, laparotomy (5 heads)was applied. The pain of the body surface and the extremities excluding the tail was not found, and the induction time of electroacupuncture anesthesia was approximately 1 minute. As for the reactions with electroacupuncture anesthesia, the head part was directed to backward, blepharoreaction was mild and the consciousness was vivid. The class of anesthesia effect was excellent in 4 heads and was poor in 1 head. The pain was not observed and bleeding was comparatively small volume during surgery in excellent group.

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A Test of Fit for Inverse Gaussian Distribution Based on the Probability Integration Transformation (확률적분변환에 기초한 역가우스분포에 대한 적합도 검정)

  • Choi, Byungjin
    • The Korean Journal of Applied Statistics
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    • v.26 no.4
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    • pp.611-622
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    • 2013
  • Mudholkar and Tian (2002) proposed an entropy-based test of fit for the inverse Gaussian distribution; however, the test can be applied to only the composite hypothesis of the inverse Gaussian distribution with an unknown location parameter. In this paper, we propose an entropy-based goodness-of-fit test for an inverse Gaussian distribution that can be applied to the composite hypothesis of the inverse Gaussian distribution as well as the simple hypothesis of the inverse Gaussian distribution with a specified location parameter. The proposed test is based on the probability integration transformation. The critical values of the test statistic estimated by simulations are presented in a tabular form. A simulation study is performed to compare the proposed test under some selected alternatives with Mudholkar and Tian (2002)'s test in terms of power. The results show that the proposed test has better power than the previous entropy-based test.

Overview of Methodological Quality of Systematic Reviews about Gastric Cancer Risk and Protective Factors

  • Li, Lun;Ying, Xiang-Ji;Sun, Tian-Tian;Yi, Kang;Tian, Hong-Liang;Sun, Rao;Tian, Jin-Hui;Yang, Ke-Hu
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2069-2079
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    • 2012
  • Background and Objective: A comprehensive overall review of gastric cancer (GC) risk and protective factors is a high priority, so we conducted the present study. Methods: Systematic searches in common medical electronic databases along with reference tracking were conducted to include all kinds of systematic reviews (SRs) about GC risk and protective factors. Two authors independently selected studies, extracted data, and evaluated the methodological qualities and the quality of evidence using R-AMSTAR and GRADE approaches. Results: Beta-carotene below 20 mg/day, fruit, vegetables, non-fermented soy-foods, whole-grain, and dairy product were GC protective factors, while beta-carotene 20 mg/day or above, pickled vegetables, fermented soy-foods, processed meat 30g/d or above, or salty foods, exposure to alcohol or smoking, occupational exposure to Pb, overweight and obesity, helicobacter pylori infection were GC risk factors. So we suggested screening and treating H. pylori infection, limiting the amount of food containing risk factors (processed meat consumption, beta-carotene, pickled vegetables, fermented soy-foods, salty foods, alcohol), stopping smoking, avoiding excessive weight gain, avoidance of Pb, and increasing the quantity of food containing protective components (fresh fruit and vegetables, non-fermented soy-foods, whole-grain, dairy products). Conclusions: The conclusions and recommendations of our study were limited by including SRs with poor methodological bases and low quality of evidence, so that more research applying checklists about assessing the methodological qualities and reporting are needed for the future.

Prognostic Value of MGMT Promoter Methylation and TP53 Mutation in Glioblastomas Depends on IDH1 Mutation

  • Wang, Kai;Wang, Yin-Yan;Ma, Jun;Wang, Jiang-Fei;Li, Shao-Wu;Jiang, Tao;Dai, Jian-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10893-10898
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    • 2015
  • Several molecular markers have been proposed as predictors of outcome in patients with glioblastomas. We investigated the prognostic significance of $O^6$-methylguanine-DNA methyltransferase (MGMT) promoter methylation and TP53 mutation status dependent on isocitrate dehydrogenase 1 (IDH1) mutation in glioblastoma patients. A cohort of 78 patients with histologically confirmed glioblastomas treated with radiation therapy and chemotherapy were reviewed retrospectively. We evaluated the prognostic value of MGMT promoter methylation and TP53 mutation status with regard to progression-free survival (PFS) and overall survival (OS). It was revealed that mutations in IDH1, promoter methylation of MGMT, TP53 mutation, age, Karnofsky performance status (KFS), and extension of resection were independent prognostic factors. In patients with an IDH1 mutation, those with an MGMT methylation were associated with longer PFS (p=0.016) and OS (p=0.013). Nevertheless, the presence of TP53 mutation could stratify the PFS and OS of patients with IDH1 wild type (p=0.003 and 0.029 respectively, log-rank). The MGMT promoter methylation and TP53 mutation were associated with a favorable outcome of patients with and without mutant IDH1, respectively. The results indicate that glioblastomas with MGMT methylation or TP53 mutations have improved survival that may be influenced by IDH1 mutation status.

TianYuanShu and Numeral Systems in Eastern Asia (천원술(天元術)과 기수법(記數法))

  • Hong, Sung Sa;Hong, Young Hee;Lee, Seung On
    • Journal for History of Mathematics
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    • v.25 no.4
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    • pp.1-10
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    • 2012
  • In Chinese mathematics, there have been two numeral systems, namely one in spoken language for recording and the other by counting rods for computations. They concerned with problems dealing with practical applications, numbers in them are concrete numbers except in the process of basic operations. Thus they could hardly develop a pure theory of numbers. In Song dynasty, 0 and TianYuanShu were introduced, where the coefficients were denoted by counting rods. We show that in this process, counting rods took over the role of the numeral system in spoken language and hence counting rod numeral system plays the role of that for abstract numbers together with the tool for calculations. Decimal fractions were also understood as denominate numbers but using the notions by counting rods, decimals were also admitted as abstract numbers. Noting that abacus replaced counting rods and TianYuanShu were lost in Ming dynasty, abstract numbers disappeared in Chinese mathematics. Investigating JianJie YiMing SuanFa(簡捷易明算法) written by Shen ShiGui(沈士桂) around 1704, we conclude that Shen noticed repeating decimals and their operations, and also used various rounding methods.

Studies on Electroacupuncture Anesthesia of Pigs (돼지의 전침 마취에 관한 연구)

  • 권건오;김인봉;이성호;이성옥;김덕환;조성환;김무강;김명철;유명조
    • Journal of Veterinary Clinics
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    • v.16 no.2
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    • pp.409-412
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    • 1999
  • To establish the electroacupuncture anesthesia for pigs, 6 piglets (Landrace mixed, 1 month old, 3.7~5.3 kg, female: 3 heads and male: 3 heads) were examined. The acupoints used for porcine electroacupuncture anesthesia were An-shen, and Tian-ping and Bai-hui. After horizontal insertion of needle to left and right An-shen, and perpendicular insertion to Tian-ping and Bai-hui, respectively, positive electrode was connected at right An-shen and Tian-ping, and negative electrode was connected at left An-shen and Bai-hui using veterinary electroacupuncture anesthesia apparatus, respectively. Electric condition was 3 V and 30 Hz. To examine the effect of electroacupuncture anesthesia, laparotomy (4 heads) and castration (2 heads)were applied. The induction time of electroacupuncture anesthesia was very rapid and about 1 minute, and pain of the body surface including the extremities was not detected. As for the reactions with electroacupuncture anesthesia, the head was directed to backward, nasal part was curved to one side, and blepharum was closed in part of changed nasal part. In addition, consciousness was vivid, and muscle tension and lift of the tail were observed in early stage but was relaxated afterwards. The pain was not found during incision and suture, bleeding was comparatively small volume and the class of anesthesia effect was excellent.

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Studies on canine Electroacupuncture Anesthesia 2. Investigation on the Effect of Dorsal Acupoints (개의 전침마취에 관한 연구 2. 배부혈위의 효과에 대한 검토)

  • 김덕환;유명조;조성환;이성호;이성옥;김인봉;권건오
    • Journal of Veterinary Clinics
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    • v.18 no.4
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    • pp.311-314
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    • 2001
  • To elucidate the effect of dorsal acupoints for canine electroacupuncture anesthesia, mongrel dogs(6 heads: 2.6-10.5kg, 3 males and 3 females) were used. After needling perpendicularly to Tian-Ping(GV-5) and Bai-Hui(GV-20), the electrodes were connected with positive to Tian-Ping and negative to Bi-hui, respectively using with veterinary electroacupuncture apparatus(TEC AM-3000). The electric conditions were 2-4V and 30 Hz. The pain of body surface was checked by hemostatic forceps. The effect of electroacupuncture andesthesia was appreciated by application of laparotomy(2 heads), ear trimming and tail amputation(1 head), castration(2 heads) and enterotomy(1 head), respectively. Induction time, clinical findings and operation findings were investigated under the electroacupuncture anesthesia. The induction time of electroacupuncture anesthesia was very rapid, approximately 1 minute and the pain of body surface including the extremities was not detected. As for clinical findings during electroacupuncture anesthesia, consciousness was evident, pupil reflex was weak and blepharoreaction was existed. As for operation findings, pain was not detected during incision and suture, and bleeding was relatively small volume. The grade of electroacupuncture anesthesia was excellent in all cases applied with ear trimming and tail amputation, laparatomy, castration and enterotomy. Considering above all findings, it was thought that electroacupuncture stimulation at Tian-Ping and Bai-hui examined in the present study induced excellent electroacupuncture anesthesia for dogs.

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Synthesis, Structures and Properties of Three Metal-organic Frameworks Based on 3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylic Acid

  • Liang, Peng;Ren, Tian-Tian;Tian, Wei-Man;Xu, Wen-Jia;Pan, Gang-Hong;Yin, Xian-Hong
    • Bulletin of the Korean Chemical Society
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    • v.35 no.1
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    • pp.182-188
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    • 2014
  • Three new transition metal complexes based on Ozagrel $[Cu(Ozagrel)]_n$ (1), $[Zn(Ozagrel)(Cl)]_n$ (2), ${[Mn_2-(Ozagrel)(1,4-ndc)_2]{\cdot}(H_2O)}_n$ (3), (Ozagrel = 3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylic acid; 1,4-ndc = 1,4-Naphthalenedicarboxylic acid) have been hydrothermally synthesized and characterized by elemental analyse, IR, TG, PXRD, electrochemical analysis and single crystal X-ray diffraction. X-ray structure analysis reveals that 1 and 3 are 3D coordination polymers, while complex 2 is a two-dimensional network polymer, the 2D layers are further packed into 3D supramolecular architectures that are connected through hydrogen bonds. The electrochemistry of 1-3 was studied by cyclic voltammetry in methanol and water using a glassy carbon working electrode. Also, thermal decomposition process and powder X-ray diffraction of complexes were investigated.

Experimental and numerical study on the collapse failure of long-span transmission tower-line systems subjected to extremely severe earthquakes

  • Tian, Li;Fu, Zhaoyang;Pan, Haiyang;Ma, Ruisheng;Liu, Yuping
    • Earthquakes and Structures
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    • v.16 no.5
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    • pp.513-522
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    • 2019
  • A long-span transmission tower-line system is indispensable for long-distance electricity transmission across a large river or valley; hence, the failure of this system, especially the collapse of the supporting towers, has serious impacts on power grids. To ensure the safety and reliability of transmission systems, this study experimentally and numerically investigates the collapse failure of a 220 kV long-span transmission tower-line system subjected to severe earthquakes. A 1:20 scale model of a transmission tower-line system is constructed in this research, and shaking table tests are carried out. Furthermore, numerical studies are conducted in ABAQUS by using the Tian-Ma-Qu material model, the results of which are compared with the experimental findings. Good agreement is found between the experimental and numerical results, showing that the numerical simulation based on the Tian-Ma-Qu material model is able to predict the weak points and collapse process of the long-span transmission tower-line system. The failure of diagonal members at weak points constitutes the collapse-inducing factor, and the ultimate capacity and weakest segment vary with different seismic wave excitations. This research can further enrich the database for the seismic performance of long-span transmission tower-line systems.