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고양이의 전침마취에 관한 연구 (Studies on Feline Electroacupuncture Anesthesia)

  • 김인봉;김무강;조성환;김덕환;유명조;이성호;이성옥;권건오;김명철
    • 한국임상수의학회지
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    • 제16권2호
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    • pp.413-416
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    • 1999
  • To establish feline electroacupuncture anesthesia, 5 cats (mixed, 1 month old, 0.4~0.5 kg, female) were examined in the present study. The acupoints used for feline electroacupuncture anesthesia were Tian-ping and Bai-hui. After perpendicular insertion of needle to Tian-ping and Bai-hui, respectively, positive electrode was connected at Tian-ping and negative electrode was connected at Bai-hui, respectively, Electric condition was 3 V and 30 Hz. To examine the effect of electroacupuncture anesthesia, laparotomy (5 heads)was applied. The pain of the body surface and the extremities excluding the tail was not found, and the induction time of electroacupuncture anesthesia was approximately 1 minute. As for the reactions with electroacupuncture anesthesia, the head part was directed to backward, blepharoreaction was mild and the consciousness was vivid. The class of anesthesia effect was excellent in 4 heads and was poor in 1 head. The pain was not observed and bleeding was comparatively small volume during surgery in excellent group.

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확률적분변환에 기초한 역가우스분포에 대한 적합도 검정 (A Test of Fit for Inverse Gaussian Distribution Based on the Probability Integration Transformation)

  • 최병진
    • 응용통계연구
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    • 제26권4호
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    • pp.611-622
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    • 2013
  • Mudholkar와 Tian (2002)이 제시한 엔트로피 기반 검정은 위치모수와 척도모수가 모두 알려져 있지 않거나 척도 모수만 알려져 있는 역가우스분포의 적합을 알아보고자 하는 경우에만 사용이 가능하다. 본 논문에서는 위치모수와 척도모수가 모두 알려져 있거나 위치모수만 알려져 있는 역가우스분포의 적합에도 적용할 수 있는 엔트로피 기반 적합도 검정을 소개한다. 이 검정은 확률적분변환에 기초를 두고 있다. 모의실험을 통해서 추정한 표본크기와 윈도크기에 따른 검정통계량의 기각값과 근사기각값을 얻기 위한 계산공식을 제시한다. 제안한 검정과 Mudholkar와 Tian (2002)의 검정을 검정력 측면에서의 성능을 비교하고자 모의실험을 수행한다. 모의실험 결과에서 제안한 검정은 기존의 엔트로피 기반 검정보다 더 좋은 검정력을 가지는 것으로 나타난다.

Overview of Methodological Quality of Systematic Reviews about Gastric Cancer Risk and Protective Factors

  • Li, Lun;Ying, Xiang-Ji;Sun, Tian-Tian;Yi, Kang;Tian, Hong-Liang;Sun, Rao;Tian, Jin-Hui;Yang, Ke-Hu
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권5호
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    • pp.2069-2079
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    • 2012
  • Background and Objective: A comprehensive overall review of gastric cancer (GC) risk and protective factors is a high priority, so we conducted the present study. Methods: Systematic searches in common medical electronic databases along with reference tracking were conducted to include all kinds of systematic reviews (SRs) about GC risk and protective factors. Two authors independently selected studies, extracted data, and evaluated the methodological qualities and the quality of evidence using R-AMSTAR and GRADE approaches. Results: Beta-carotene below 20 mg/day, fruit, vegetables, non-fermented soy-foods, whole-grain, and dairy product were GC protective factors, while beta-carotene 20 mg/day or above, pickled vegetables, fermented soy-foods, processed meat 30g/d or above, or salty foods, exposure to alcohol or smoking, occupational exposure to Pb, overweight and obesity, helicobacter pylori infection were GC risk factors. So we suggested screening and treating H. pylori infection, limiting the amount of food containing risk factors (processed meat consumption, beta-carotene, pickled vegetables, fermented soy-foods, salty foods, alcohol), stopping smoking, avoiding excessive weight gain, avoidance of Pb, and increasing the quantity of food containing protective components (fresh fruit and vegetables, non-fermented soy-foods, whole-grain, dairy products). Conclusions: The conclusions and recommendations of our study were limited by including SRs with poor methodological bases and low quality of evidence, so that more research applying checklists about assessing the methodological qualities and reporting are needed for the future.

Prognostic Value of MGMT Promoter Methylation and TP53 Mutation in Glioblastomas Depends on IDH1 Mutation

  • Wang, Kai;Wang, Yin-Yan;Ma, Jun;Wang, Jiang-Fei;Li, Shao-Wu;Jiang, Tao;Dai, Jian-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권24호
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    • pp.10893-10898
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    • 2015
  • Several molecular markers have been proposed as predictors of outcome in patients with glioblastomas. We investigated the prognostic significance of $O^6$-methylguanine-DNA methyltransferase (MGMT) promoter methylation and TP53 mutation status dependent on isocitrate dehydrogenase 1 (IDH1) mutation in glioblastoma patients. A cohort of 78 patients with histologically confirmed glioblastomas treated with radiation therapy and chemotherapy were reviewed retrospectively. We evaluated the prognostic value of MGMT promoter methylation and TP53 mutation status with regard to progression-free survival (PFS) and overall survival (OS). It was revealed that mutations in IDH1, promoter methylation of MGMT, TP53 mutation, age, Karnofsky performance status (KFS), and extension of resection were independent prognostic factors. In patients with an IDH1 mutation, those with an MGMT methylation were associated with longer PFS (p=0.016) and OS (p=0.013). Nevertheless, the presence of TP53 mutation could stratify the PFS and OS of patients with IDH1 wild type (p=0.003 and 0.029 respectively, log-rank). The MGMT promoter methylation and TP53 mutation were associated with a favorable outcome of patients with and without mutant IDH1, respectively. The results indicate that glioblastomas with MGMT methylation or TP53 mutations have improved survival that may be influenced by IDH1 mutation status.

천원술(天元術)과 기수법(記數法) (TianYuanShu and Numeral Systems in Eastern Asia)

  • 홍성사;홍영희;이승온
    • 한국수학사학회지
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    • 제25권4호
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    • pp.1-10
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    • 2012
  • 중국의 명수법은 기록은 구어체를 사용하고, 계산은 산대를 사용하는 이중 구조를 가지고 있었다. 또 산서는 실생활의 문제만 다루는 과정에서 수학적 구조를 나타내는 방법을 택하여 계산 과정을 제외하면 이들에서 취급한 수는 모두 명수(名數)들이어서 순수한 수론의 발전을 이룰 수 없었다. 송대에 0의 도입과 함께, 천원술의 표현에서 나타나는 계수를 산대로 표시하는 방법을 통하여, 산대가 계산 도구와 함께 추상수의 기수법(記數法)이 되는 과정을 밝힌다. 수량의 단위를 사용한 소수의 표현도 이 과정에서 산대 표현으로 대치되었다. 그러나 명대에 산대 계산이 주산으로 대치되고 천원술이 잊히게 되어 추상수의 개념도 함께 잊히게 되었다. 청대의 산학자 심사계(沈士桂)가 저서 간첩이명산법(簡捷易明算法)에서 분수의 소수표시와 계산을 하는 과정에서 순환소수를 인지하고 이들의 계산법을 확립한 것도 보인다.

돼지의 전침 마취에 관한 연구 (Studies on Electroacupuncture Anesthesia of Pigs)

  • 권건오;김인봉;이성호;이성옥;김덕환;조성환;김무강;김명철;유명조
    • 한국임상수의학회지
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    • 제16권2호
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    • pp.409-412
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    • 1999
  • To establish the electroacupuncture anesthesia for pigs, 6 piglets (Landrace mixed, 1 month old, 3.7~5.3 kg, female: 3 heads and male: 3 heads) were examined. The acupoints used for porcine electroacupuncture anesthesia were An-shen, and Tian-ping and Bai-hui. After horizontal insertion of needle to left and right An-shen, and perpendicular insertion to Tian-ping and Bai-hui, respectively, positive electrode was connected at right An-shen and Tian-ping, and negative electrode was connected at left An-shen and Bai-hui using veterinary electroacupuncture anesthesia apparatus, respectively. Electric condition was 3 V and 30 Hz. To examine the effect of electroacupuncture anesthesia, laparotomy (4 heads) and castration (2 heads)were applied. The induction time of electroacupuncture anesthesia was very rapid and about 1 minute, and pain of the body surface including the extremities was not detected. As for the reactions with electroacupuncture anesthesia, the head was directed to backward, nasal part was curved to one side, and blepharum was closed in part of changed nasal part. In addition, consciousness was vivid, and muscle tension and lift of the tail were observed in early stage but was relaxated afterwards. The pain was not found during incision and suture, bleeding was comparatively small volume and the class of anesthesia effect was excellent.

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개의 전침마취에 관한 연구 2. 배부혈위의 효과에 대한 검토 (Studies on canine Electroacupuncture Anesthesia 2. Investigation on the Effect of Dorsal Acupoints)

  • 김덕환;유명조;조성환;이성호;이성옥;김인봉;권건오
    • 한국임상수의학회지
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    • 제18권4호
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    • pp.311-314
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    • 2001
  • To elucidate the effect of dorsal acupoints for canine electroacupuncture anesthesia, mongrel dogs(6 heads: 2.6-10.5kg, 3 males and 3 females) were used. After needling perpendicularly to Tian-Ping(GV-5) and Bai-Hui(GV-20), the electrodes were connected with positive to Tian-Ping and negative to Bi-hui, respectively using with veterinary electroacupuncture apparatus(TEC AM-3000). The electric conditions were 2-4V and 30 Hz. The pain of body surface was checked by hemostatic forceps. The effect of electroacupuncture andesthesia was appreciated by application of laparotomy(2 heads), ear trimming and tail amputation(1 head), castration(2 heads) and enterotomy(1 head), respectively. Induction time, clinical findings and operation findings were investigated under the electroacupuncture anesthesia. The induction time of electroacupuncture anesthesia was very rapid, approximately 1 minute and the pain of body surface including the extremities was not detected. As for clinical findings during electroacupuncture anesthesia, consciousness was evident, pupil reflex was weak and blepharoreaction was existed. As for operation findings, pain was not detected during incision and suture, and bleeding was relatively small volume. The grade of electroacupuncture anesthesia was excellent in all cases applied with ear trimming and tail amputation, laparatomy, castration and enterotomy. Considering above all findings, it was thought that electroacupuncture stimulation at Tian-Ping and Bai-hui examined in the present study induced excellent electroacupuncture anesthesia for dogs.

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Synthesis, Structures and Properties of Three Metal-organic Frameworks Based on 3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylic Acid

  • Liang, Peng;Ren, Tian-Tian;Tian, Wei-Man;Xu, Wen-Jia;Pan, Gang-Hong;Yin, Xian-Hong
    • Bulletin of the Korean Chemical Society
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    • 제35권1호
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    • pp.182-188
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    • 2014
  • Three new transition metal complexes based on Ozagrel $[Cu(Ozagrel)]_n$ (1), $[Zn(Ozagrel)(Cl)]_n$ (2), ${[Mn_2-(Ozagrel)(1,4-ndc)_2]{\cdot}(H_2O)}_n$ (3), (Ozagrel = 3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylic acid; 1,4-ndc = 1,4-Naphthalenedicarboxylic acid) have been hydrothermally synthesized and characterized by elemental analyse, IR, TG, PXRD, electrochemical analysis and single crystal X-ray diffraction. X-ray structure analysis reveals that 1 and 3 are 3D coordination polymers, while complex 2 is a two-dimensional network polymer, the 2D layers are further packed into 3D supramolecular architectures that are connected through hydrogen bonds. The electrochemistry of 1-3 was studied by cyclic voltammetry in methanol and water using a glassy carbon working electrode. Also, thermal decomposition process and powder X-ray diffraction of complexes were investigated.

Experimental and numerical study on the collapse failure of long-span transmission tower-line systems subjected to extremely severe earthquakes

  • Tian, Li;Fu, Zhaoyang;Pan, Haiyang;Ma, Ruisheng;Liu, Yuping
    • Earthquakes and Structures
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    • 제16권5호
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    • pp.513-522
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    • 2019
  • A long-span transmission tower-line system is indispensable for long-distance electricity transmission across a large river or valley; hence, the failure of this system, especially the collapse of the supporting towers, has serious impacts on power grids. To ensure the safety and reliability of transmission systems, this study experimentally and numerically investigates the collapse failure of a 220 kV long-span transmission tower-line system subjected to severe earthquakes. A 1:20 scale model of a transmission tower-line system is constructed in this research, and shaking table tests are carried out. Furthermore, numerical studies are conducted in ABAQUS by using the Tian-Ma-Qu material model, the results of which are compared with the experimental findings. Good agreement is found between the experimental and numerical results, showing that the numerical simulation based on the Tian-Ma-Qu material model is able to predict the weak points and collapse process of the long-span transmission tower-line system. The failure of diagonal members at weak points constitutes the collapse-inducing factor, and the ultimate capacity and weakest segment vary with different seismic wave excitations. This research can further enrich the database for the seismic performance of long-span transmission tower-line systems.