• Title/Summary/Keyword: Three Rs

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Effects of Feeding Level of Concentrate on the Digestible Nutrient Intake, Using Efficiency of Nutrients and Nitrogen Retention of Korean Black Goat Fed Whole Crop Barley Silage (청보리 사일리지 급여 시 농후사료 급여수준이 흑염소의 가소화 영양소 섭취량, 영양소 이용율 및 질소축적에 미치는 영향)

  • Choi, Sun-Ho;HwangBo, Soon;Kim, Sang-Woo;Kim, Won-Ho;Jo, Ik-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.30 no.1
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    • pp.59-66
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    • 2010
  • This study was aimed to investigate the effects of feeding level of concentrate on the digestible nutrient intake, using efficiency of nutrients and nitrogen retention of growing Korean black goats (KBG) fed on whole crop barley (WCB) silage. WCB silage with concentrates at 2.0% (BS2.0), 1.5% (BS1.5) and 1.0% (BS1.0) of BW, respectively, and rice straw with concentrate at 2.0% (RS2.0) of BW as a control. Goats for digestibility trials were assigned within each group with three animals to individual metabolism crates with Latin square design. Digestible crude protein (DCP) intakes goats in control, BS2.0 and BS1.5 was significantly higher than that in BS 1.0 (p<0.05). Digestible NFC intakes of goats in BS2.0 and BS 1.5 was significantly higher than that in BS1.0 (p<0.05). The highest Average daily gain (ADG) were recorded in group BS2.0 followed by BS1.5, RS2.0 and BS1.0 (p<0.05). The highest DM digestibility was shown in group BS1.5 treatments (p<0.05). Nitrogen retentions in RS2.0, BS2.0 and BS1.0 were significantly higher than that in group BS1.0 (p<0.05). The results obtained from this study suggested that feeding level of concentrate seems to be proper at 1.5% of BW to achieve the best performance when black goats are fed WCB silage as a roughage source with concentrate.

The interaction of Apolipoprotein A5 gene promoter region T-1131C polymorphism (rs12286037) and lifestyle modification on plasma triglyceride levels in Japanese

  • Yamasaki, Masayuki;Mutombo, Paulin Beya wa Bitadi;Iwamoto, Mamiko;Nogi, Akiko;Hashimoto, Michio;Nabika, Toru;Shiwaku, Kuninori
    • Nutrition Research and Practice
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    • v.9 no.4
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    • pp.379-384
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    • 2015
  • BACKGROUND/OBJECTIVE: Apolipoprotein A5 gene promoter region T-1131C polymorphism (APOA5 T-1131C) is known to be associated with elevated plasma TG levels, although little is known of the influence of the interaction between APOA5 T-1131C and lifestyle modification on TG levels. To investigate this matter, we studied APOA5 T-1131C and plasma TG levels of subjects participating in a three-month lifestyle modification program. SUBJECTS/METHODS: A three-month lifestyle modification program was conducted with 297 participants (Age: $57{\pm}8years$) in Izumo City, Japan, from 2001-2007. Changes in energy balance (the difference between energy intake and energy expenditure) and BMI were used to evaluate the participants' responses to the lifestyle modification. RESULTS: Even after adjusting for confounding factors, plasma TG levels were significantly different at baseline among three genotype subgroups: TT, $126{\pm}68mg/dl$; TC, $134{\pm}74mg/dl$; and CC, $172{\pm}101mg/dl$. Lifestyle modification resulted in significant reductions in plasma TG levels in the TT, TC, and CC genotype subgroups: $-21.9{\pm}61.0mg/dl$, $-20.9{\pm}51.0mg/dl$, and $-42.6{\pm}78.5mg/dl$, respectively, with no significant differences between them. In a stepwise regression analysis, age, APOA5 T-1131C, body mass index (BMI), homeostasis model assessment-insulin resistance (HOMA-IR), and the 18:1/18:0 ratio showed independent association with plasma TG levels at baseline. In a general linear model analysis, APOA5 T-1131C C-allele carriers showed significantly greater TG reduction with decreased energy balance than wild type carriers after adjustment for age, gender, and baseline plasma TG levels. CONCLUSIONS: The genetic effects of APOA5 T-1131C independently affected plasma TG levels. However, lifestyle modification was effective in significantly reducing plasma TG levels despite the APOA5 T-1131C genotype background.

Insulin Inhibits the Expression of Adiponectin and AdipoR2 mRNA in Cultured Bovine Adipocytes

  • Sun, Y.G.;Zan, L.S.;Wang, H.B.;Guo, H.F.;Yang, D.P.;Zhao, X.L.;Gui, L.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.10
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    • pp.1429-1436
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    • 2009
  • Adiponectin is an adipocyte-derived protein that has a regulatory role in energy homeostasis and influences insulin sensitivity. Its effects on glucose utilization and lipid metabolism are mediated by AdipoR1 and AdipoR2. How insulin affects adiponectin gene expression and secretion is still controversial. This study was conducted to determine the expression of adiponectin, AdipRs and $PPAR-\gamma$ during the differentiation of bovine preadipocytes and the effect of insulin on expression of these genes in bovine adipocytes. The bovine preadipocytes started to accumulate lipids three days after differentiation was induced, with increased expression of adiponectin, AdipoR2 and $PPAR-\gamma$ mRNAs. Insulin decreased the expression of adiponectin mRNA in a dose- and time-dependent fashion, and the inhibition was detectable at insulin concentrations as low as 10 nM and as early as 2 h after addition of 100 nM insulin. Insulin also inhibited the expression of AdipoR2 mRNA at concentrations from 1 to 1,000 nM or 24 h after addition of 100 nM insulin, but did not affect the expression of AdipoR1 in bovine adipocytes. Inhibition of PI3K with LY294002 reversed the inhibition of adiponectin and AdipoR2 mRNA expression by insulin. These results suggest that insulin suppresses the expression of adiponectin and AdipoR2 at least partially via the PI3K signal pathway.

INTEGRATED WATER RESOURCES AND QUALITY MANAGEMENT SYSTEM USING GIS/RS TECHNOLOGIES

  • Shim, Kyu-Cheoul;Shim, Soon-Bo;Lee, Yo-Sang
    • Water Engineering Research
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    • v.3 no.2
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    • pp.85-92
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    • 2002
  • There has been continuous efforts to manage water resources for the required water quality criterion at river channel in Korea. However, we could obtain the partial improvement only for the point sources such as, waste waters from urban and factory site through the water quality management. Therefore, it is strongly needed that the best management practice throughout the river basin fur water quality management including non-point sources pollutant loads. This problem should be resolved by recognizing the non-point sources pollutant loads from the upstream river basin to the outlet of the basin depends on the landuse and soil type characteristics of the river basin using the computer simulation by a distributed model based on the detailed investigation and application of Geographic Information System (GIS). The purpose of this study is consisted of the three major distributions, which are the investigation of spread non-point sources pollutants throughout the river basin, development of the base maps to represent and interpret the input and outputs of the distributed simulation model, and prediction of non-point sources pollutant loads at the outlet of a up-stream river basin using Agricultural Non-Point Sources Model (AGNPS). For the validation purpose, the Seom-Jin River basin was selected with two flood events in 1998. The results of this application showed that the use of combined a distributed model and an application of GIS was very effective fur the best water resources and quality management practice throughout the river basin

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High-Dose Simvastatin Is Effective in Preventing Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage : A Prospective Cohort Study in Korean Patients

  • Woo, Sung Woong;Kim, Jae Hoon;Kang, Hee In;Kim, Deok Ryeong;Moon, Byung Gwan;Kim, Joo Seung
    • Journal of Korean Neurosurgical Society
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    • v.58 no.4
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    • pp.328-333
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    • 2015
  • Objective : The goal of this study was to assess the effect of high-dose simvastatin on cerebral vasospasm and its clinical outcome after aneurysmal subarachnoid hemorrhage (SAH) in Korean patients. Methods : This study was designed as a prospective observational cohort study. Its subjects were aneurysmal SAH patients who had undergone aneurysm clipping or coiling. They were assigned to 1 of 3 groups : the 20 mg, 40 mg, and 80 mg simvastatin groups. The primary end-point was the occurrence of symptomatic vasospasm. The clinical outcome was assessed with the modified Rankin Scale (mRS) score after 1 month and 3 months. The risk factors of the development of vasospasm were assessed by logistic regression analysis. Results : Ninety nine patients with aneurysmal SAH were treated and screened. They were sequentially assigned to the 20 mg (n=22), 40 mg (n=34), and 80 mg (n=31) simvastatin groups. Symptomatic vasospasm occurred in 36.4% of the 20 mg group, 8.8% of the 40 mg group, and 3.2% of the 80 mg group (p=0.003). The multiple logistic regression analysis showed that poor Hunt-Hess grades (OR=5.4 and 95% CI=1.09-26.62) and high-dose (80 mg) simvastatin (OR=0.09 and 95% CI=0.1-0.85) were independent factors of symptomatic vasospasm. The clinical outcomes did not show a significant difference among the three groups. Conclusion : This study demonstrated that 80 mg simvastatin treatment was effective in preventing cerebral vasospasm after aneurysmal SAH, but did not improve the clinical outcome in Korean patients.

Effect of Elastic Band Exercise on the Plantar Pressure and Maximum Muscle Strength in Female University Students Wearing High Heels

  • Jung, Bum-Chul;Yoo, Kyung-Tae;Kim, Young-Hwan
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.4
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    • pp.83-92
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    • 2017
  • PURPOSE: The purpose of this study was to investigate the effect of the elastic band and stretching exercise program on ankle joint maximal voluntary isometric contraction (MVIC) and plantar pressure in high-heel wearing women in their 20s. METHODS: Twenty women in their twenties were randomly assigned to the experimental group (n=10) and the control group (n=10). The experimental group (n=10) performed the elastic band exercise program, while the control group (n=10) performed the stretching exercise program. Both exercise programs were performed three times a week for a total of four weeks. The BTE Primus RS was used in order to measure the ankle joint MVIC during dorsiflexion, plantar flexion, inversion, and eversion. Maximum pressure ($N/cm^2$), average pressure ($N/cm^2$) were measured using the Pedoscan. SPSS v. 21.0 software was used for all statistical analyses in this study. RESULTS: The measurement of the ankle joint's MVIC revealed that in inversion, a significant change in both feet was seen in both the experimental and control groups. In eversion, there was a significant change in both feet only in the experimental group. In terms of the rest of the results, no significant changes were visible. With regard to the plantar pressure, no significant results were seen for either foot in the comparison between or within the groups. CONCLUSION: Exercise program using elastic band and exercise program using stretching were effective on MVIC of ankle joint muscles, although it had no effect on changes of plantar pressure.

EFFECTS OF THE HERBICIDE, BUTACHLOR, ON NITROGEN FIXATION IN PHOTOTROPHIC NONSULFUR BACTERIA

  • Lee, Kyung-Mi;Kim, Jai-Soo;Lee, Hyun-Soon
    • Environmental Engineering Research
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    • v.12 no.4
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    • pp.136-147
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    • 2007
  • In an effort to identify possible microbes for seeking bioagents for remediation of herbicide-contaminated soils, seven species of phototrophic nonsulfur bacteria (Rhodobacter capsulatus and sphaeroides, Rhodospirillum rubrum, Rhodopseudomonas acidophila, blastica and viridis, Rhodomicrobium vannielii) were grown in the presence of the herbicide, butachlor, and bacterial growth rates and nitrogen fixation were measured with different carbon sources. Under general conditions, all species showed 17-53% reductions in growth rate following butachlor treatment. Under nitrogen-fixing conditions, Rb. capsulatus and Rs. rubrum showed 1-4% increases in the growth rates and 2-10% increases in nitrogen-fixing abilities, while the other 5 species showed decreases of 17-47% and 17-85%, respectively. The finding that Rp. acidophila, Rp. blastica, Rp. viridis and Rm. vannielii showed stronger inhibitions of nitrogenase activity seems to indicate that species in genera Rhodobacter and Rhodospirillum are less influenced by butachlor than those in Rhodopseudomonas and Rhodomicrobium in terms of nitrogen-fixing ability. Overall, nitrogenase activity was closely correlated with both growth rate and glutamine synthetase activity (representing nitrogen metabolism). When the carbon sources were compared, pyruvate (three carbons) was best for all species in terms of growth rate and nitrogen fixation, with malate (four carbons) showing intermediate values and ribose(five carbons) showing the lowest; these trends did not change in response to butachlor treatment. We verified that each of the 7 species had a plasmid ($12.2{\sim}23.5\;Kb$). We found that all 7 species could use butachlor as a sole carbon source and 3 species were controlled by plasmid-born genes, but it is doubtful whether plasmid-born genes were responsible to nitrogen fixation.

Applicability of VariousInterpolation Approaches for High Resolution Spatial Mapping of Climate Data in Korea (남한 지역 고해상도 기후지도 작성을 위한 공간화 기법 연구)

  • Jo, Ayeong;Ryu, Jieun;Chung, Hyein;Choi, Yuyoung;Jeon, Seongwoo
    • Journal of Environmental Impact Assessment
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    • v.27 no.5
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    • pp.447-474
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    • 2018
  • The purpose of this study is to build a new dataset of spatially interpolated climate data of South Korea by performing various geo-statistical interpolation techniques for comparison with the LDAPS grid data of KMA. Among 595 observation data in 2017, 80 % of the total points and remaining 117 points were used for spatial mapping and quantification,respectively. IDW, cokriging, and kriging were performed via the ArcGIS10.3.1 software and Python3.6.4, and each result was then divided into three clusters and four watersheds for statistical verification. As a result, cokriging produced the most suitable grid climate data for instantaneous temperature. For 1-hr accumulated precipitation, IDW was most suitable for expressing local rainfall effects.

Framework for Information Integration and Customization Using Ontology and Case-based Reasoning (온톨로지 및 사례기반추론을 이용한 맞춤형 통합 정보 생성 프레임워크의 제안)

  • Lee, Hyun-Jung;Sohn, M-Ye
    • Journal of Intelligence and Information Systems
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    • v.15 no.4
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    • pp.141-158
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    • 2009
  • The requirements of knowledge customization have increased as information resources have become more various and the numbers of the resources are increased. Even if the method for collecting the information has improved like Really Simple Syndication (RSS), information users are still struggling for extracting and customizing the required information through the Web. To reduce the burden, we offer the dynamic knowledge customization framework by using ontology-based CBR. The framework consisting of three phases is comprised of the conversion phase of web information as a machine-accessible case, the extraction phase to find a case appropriate for information users' requirements, and the case customization phase to create knowledge depending on information user's requirements. Newly, the dynamic and intensity-based similarity is adopted to support timely dynamic change of users' requirements. The framework has adopted to create traveler's knowledge to the level users wanted.

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Study on the Ambiguity Difference Adjustment between Reference Station Cells for the Improvement in Rover's Continuous Network-RTK Positioning (Network RTK 항체의 불연속 위치 결정 개선을 위한 기준국 셀간 미지정수 차이 조정 연구)

  • Park, Byung-Woon;Song, June-Sol;Kee, Chang-Don
    • Journal of Advanced Navigation Technology
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    • v.16 no.4
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    • pp.619-626
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    • 2012
  • One-way Network-RTK(Real Time Kinematics) is considered as a method which can satisfy moving vehicle's recently-required high accuracy and mobility. When we use one-way Network RTK for vehicle navigation, multiple cells-based system is required to provide the service continuously in wide area. The rover which moves through various cells inevitably experiences a correction discontinuity, which is not eliminated by the DD(Double Difference) method and to cause 13cm(horizontal) and 48cm(vertical) position error. We suggest three solutions to reduce this discontinuity, which are identification of master RS with neighbor networks, duplication of communication module to receive corrections from other cells, and ambiguity adjustment between neighbor cells. All of our suggestions reduce the error to 1/4 wavelength in measurement and 3cm in position-domain, and we suggest the ambiguity adjustment is the best when we consider the extendibility of service area and the cost of rover device.