• The Journal of Korean Academy of Prosthodontics
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• v.55 no.4
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• pp.389-393
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• 2017

Purpose: The aim of this study is to evaluate the flexural strength of flexible resins and the flexibility of different resin splint (RS) systems in comparison with resin wire splint (RWS) system. Materials and methods: Three different resin materials (G-aenial flo, GA, GC; Superbond, SB, Sun medical; G-fix, GF, GC) were tested flexural strength test in accordance with ISO-4049:2000. For the flexibility test of splint systems, a artificial model with resin teeth was used to evaluate three types of resin splint systems (GA, SB, and GF) and one resin wire splint system. The left central incisor was simulated 'injured teeth' with third degree mobility. Three consecutively repeated measurements of periotest value were taken in horizontal direction, before and after splinting to access tooth mobility. The splinting effect was calculated through the periotest value. Differences were evaluated through One-way Anova and Tukey HDS post-hoc tests for pair-wise comparison (${\alpha}=.05$). Results: Although GA group showed significant higher flexural strength than SB and GF groups, all of three different resin splint systems produced a significantly higher and rigid splinting effect compared with 016" resin-wire splint system (P < .05). Conclusion: Within the limits of an in vitro study, it can be stated that resin splint systems are too rigid and may not be acceptable to treat tooth avulsion.

• Korean Journal of Agricultural Science
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• v.40 no.2
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• pp.155-162
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• 2013

Genome-wide association study was performed on data from 266 Hanwoo steers derived from 66 sire using bovine 10K mapping chip in Hanwoo (Korean Cattle). SNPs were excluded from the analysis if they failed in over 5% of the genotypes, had median GC scores below 0.6, had GC scores under 0.6 in less than 90% of the samples, deviated in heterozygosity more than 3 standard deviations from the other SNPs and were out of Hardy-Weinberg equilibrium for a cutoff p-value of $1^{-15}$. Unmapped and SNPs on sex chromosomes were also excluded. A total of 4,522 SNPs were included in the analysis. To test an association between SNP and QTL, GWAS for five genetic mode (additive, dominant, overdominant, recessive and codominant) was implemented in this study. Three SNPs (rs29018694, ss46526851 and rs29018222) at a threshold p< $1.11{\times}10^{-5}$ were detected on BTA12 and BTA21 for dressing percentages in codominant and recessive genetic mode. The G allele for rs29018694 has 4.9% higher dressing percentage than A allele, while the T allele for ss46526851 has 2.57 % higher dressing percentage than C allele. Therefore, rs29018694 SNP showed a bigger effect than the other two SNPs (ss46526851 and rs29018222) in this study. In conclusion, this study identifies three loci with moderate effects and many loci with infinitesimally small effect across genome in Hanwoo.

• Journal of Life Science
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• v.31 no.6
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• pp.568-573
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• 2021

This study identified genomic factors associated with endoplasmic reticulum protein (ERp)29 gene expression in a genome-wide association study (GWAS) of genetic variants, including single-nucleotide polymorphisms (SNPs). In total, 373 European genes from the 1000 Genomes Project were analyzed. SNPs with an allelic frequency of less than or more than 5% were removed, resulting in 5,913,563 SNPs including in the analysis. The following expression quantitative trait loci (eQTL) from the long noncoding RNA LOC105372577 were strongly associated with ERp29 expression: rs6138266 (p<4.172e10), rs62193420 (p<1.173e10), and rs6138267 (p<2.041e10). These were strongly expressed in the testis and in the brain. The three eQTL were identified through a transcriptome-wide association study (TWAS) and showed a significant association with ERp29 and osteosarcoma amplified 9 (OS9) expression. Upstream sequences of rs6138266 were recognized by ChIP-seq data, while HaploReg was used to demonstrate how its regulatory DNA binds upstream of transcription factor 1 (USF1). There were no changes in the expression of OS9 or USF1 following ER stress.

• Korean Journal of Agricultural Science
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• v.38 no.1
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• pp.153-162
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• 2011

This study analyzed the spatio-temporal change detection of land-use and urbanization in Yongin and Anseong regions, Kyunggi Province, using three Landsat-5 TM images for 1990, 1996, and 2000. Remote sensing (RS) and geographic information system (GIS) techniques were used for image classification and result analysis. Six land-use types were classified using supervised maximum likelihood classification. In the two study areas, the land-use changed significantly, especially the decrease of arable land and forest and increase of built-up area. Spatially, the urban expansion of Yongin region showed a spreading trend mainly along the national road and expressways. But in Anseong region the expansion showed 'urban sprawl phenomenon' with irregular shape like starfish. Temporally, the urban expansion showed disparity - the growth rates of urbanized area rose from the period 1990-1996 to 1996-2000 in both study areas. The increased built-up areas were converted mainly from paddy, dry vegetation, and forest.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.4
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• pp.543-549
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• 2010

Purpose : The study was designed to investigate the changes of plantar foot pressure by different loads during walking in flatfoot. Methods : Fifteen subjects with flatfoot were recruited along with their written informed consent. They were asked to walk on plate at a self-selected and comfortable speed with loads of 0, 5, 10, and 15kg. Three walking trials were obtained and then averaged for data analysis. Foot pressure were measured from RS-Scan system (RS-Scan system, RS scan Ltd., German) and contact area, maximum force were analyzed. Results : There were significant increases on midfoot and decreases on forefoot in contact area. And there were significant increases in maximum force of foot pressure of 2nd metatarsal bone and midfoot. Conclusion : These findings revealed that flatfoot increases risk factors of metatarsal bone with different loads. Therefore, patients of flatfoot must be careful during walking with loads or activities of daily living.

• Proceedings of the KSRS Conference
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• 2006.03a
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• pp.232-235
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• 2006

해저 해빈모래가 다량 유실되어 이 지역의 장기관리를 위해 침식구간에 대한 지속적인 모니터링 작업이 필요하다. 그러나 각 구청은 지형변화 분석 작업 없이, 양빈작업에 급급하고 있어 장기효과가 나타나지 않고 있다. 그러므로 본 연구는 수심측량 및 GPS 측량을 통해 해저 해빈지대의 정확한 공간자료를 구축, RS GIS 기법을 도입하여 지형변화를 정량 정성적으로 탐지 분석하였다. 연구 결과, 해운대 해저지형은 과도한 도시개발과 하천복개공사로 지난 25년간, 평균수심 0.40m, 수표면적 $11,028m^2$, 수중체적 $2,207,884m^3$ 가량 침식되었다. 해빈지형은 지난 5년간, 평균고도 0.27m, 총면적 $6,501m^2$, 총체적 $25,667m^3$ 가량 퇴적되었다. 이의 원인은 지오그리드의 설치로 해빈모래가 서측까지 도달하지 못하고, 계절영향으로 사료된다. 본 연구는 해저 해빈지형의 정확한 측량작업으로 해안 및 지형변화에 관한 모니터링 작업을 실시하여 연안침식 현황을 분석하고, 양빈작업 및 안전한 해양레저 활동, 해수욕장 관리에 필요한 정보를 제공할 수 있을 것으로 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• v.8 no.5
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• pp.443-447
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• 1995

Fifteen Karan-Swiss male calves of 9-12 months of age were divided into three groups of five each in a randomised block design. Animals in group I were fed wheat straw ad lib. and concentrate mixture according to their requirements, while in group II and III the animals were fed with 1/3 of the required concentrate mixture replaced by UMM licks 'Ex' and 'F', respectively. The DMI (kg/day as well as per 100 kg b.wt.) were similar (p > 0.05) among different groups of animals, however, the digestibility of DM as well as OM enhanced from $52.85{\pm}1.48$ to $58.36{\pm}1.89$ and $55.33{\pm}1.48$ to $60.12{\pm}1.75$, respectively. Growth rates of the calves were $533.8{\pm}27.25$, $532.3{\pm}42.24$ and $538.4{\pm}18.68$ g/d in groups I, II and ill (p > 0.05), respectively. Body composition and N balances of the animals were not affected by supplementation of UMM licks, however, protein retention efficiency was higher in group III ($82.57{\pm}2.54$) though nonsignificant. Feed cost/day was reduced from Rs. 7.92 (group I) to Rs. 4.62 (group II) and Rs. 3.44 (group III). Hence, partial replacement of concentrates by UMM licks reduced the cost of feeding of growing calves by 41.7 to 56.6% without affecting the growth performance.

• Genomics & Informatics
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• v.9 no.2
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• pp.64-68
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• 2011

Monomelic amyotrophy (MA), also known as Hirayama disease, occurs mainly in young men and manifests as weakness and wasting of the muscles of the distal upper limbs. Here, we sought to identify a genetic basis for MA. Given the predominance of MA in males, we focused on candidate neurological disease genes located on the X chromosome, selecting two X-linked candidate genes, androgen receptor (AR ) and ubiquitin-like modifier activating enzyme 1 (UBA1). Screening for genetic variants using patients' genomic DNA revealed three known genetic variants in the coding region of the AR gene: one nonsynonymous single-nucleotide polymorphism (SNP; rs78686797) encoding Leu57Gln, and two variants of polymorphic trinucleotide repeat segments that encode polyglutamine (CAG repeat; rs5902610) and polyglycine (GGC repeat; rs3138869) tracts. Notably, the Leu57Gln polymorphism was found in two patients with MA from 24 MA patients, whereas no variants were found in 142 healthy male controls. However, the numbers of CAG and GGC repeats in the AR gene were within the normal range. These data suggest that the Leu57Gln polymorphism encoded by the X-linked AR gene may contribute to the development of MA.

• Biomedical Science Letters
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• v.26 no.1
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• pp.42-46
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• 2020

Tuberculosis (TB) remains a major health problem worldwide. TB depends not only on the characteristics of the Mycobacterium tuberculosis (MTB) but also on the genetic susceptibility of infected patients. Recent studies have suggested that FOXO3 play an important role in the human immune associated disorder, such as TB. It was previously reported that FOXO3 genetic variants associated with a risk of TB in Chinese population. In this study, we confirm whether the genetic polymorphism of the FOXO3 gene, which was previously in Chinese, is reproduced in Korean population. Of the 154 SNPs were extracted from the FOXO3 gene, reproducibility analysis of the four SNPs performed in the previous study showed that there was a statistically significant correlation in the three SNPs (rs4946935, rs1536057, rs3800228). This study suggests that polymorphism of the FOXO3 gene in Koreans may affect the onset of tuberculosis and could be used to treat and prevent tuberculosis.

• IEMEK Journal of Embedded Systems and Applications
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• v.10 no.5
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• pp.281-296
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• 2015

This paper describes a novel disaster evacuation system using embedded systems such as smart devices for crisis and emergency management. In indoor environments deployed with the Bluetooth Low Energy(BLE) beacons, smart devices detect their indoor positions from beacon messages and interact with Map Server(MS) and Route Server(RS) in the Internet over the LTE and/or Wi-Fi functions. The MS and RS generate an optimal path to the nearest emergency exit based on a novel graph generation method for less route computation, called the Disaster Evacuation Graph(DEG), for each smart device. The DEG also enables efficient processing of some constraints in the computation of route, such as load balancing in situation of different capacities of paths or exits. All data interfaces among three system components, the MS, RS, smart devices, have been defined for modular implementation of our disaster evacuation system. Our experimental system has been deployed and tested in our building thoroughly and gives a good evidence that the modular design of the system and a novel approach to compute emergency route based on the DEG is competitive and viable.