• 제목/요약/키워드: Thioamides

검색결과 14건 처리시간 0.016초

Direct and Efficient Conversion of Tertiary Thioamides to S-2-Oxo Thioesters under Solvent-free Conditions

  • Boeini, Hassan Zali;Khajeh, Aida
    • Bulletin of the Korean Chemical Society
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    • 제32권4호
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    • pp.1201-1203
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    • 2011

  • A one-pot conversion of tertiary thioamides to S-2-oxo thioesters is reported. Hence, tertiary thioamides were reacted with ${\alpha}$-halo ketones or acids under solvent-free conditions to produce the corresponding oxo-thioesters in good to excellent yields.

  • https://doi.org/10.5012/bkcs.2011.32.4.1201 인용 PDF KSCI

Synthesis of Amide from Thioamide by Treatment of SiO2 or SeO2

  • Jung, Dai-Il;Lee, Jin-A;Lee, Do-Hun;Kwak, Moon-Jung;Lee, Soo-Jin;Park, You-Mi;Park, Soon-Kyu;Kim, Hyun-Sook
    • Journal of Life Science
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    • 제9권2호
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    • pp.49-51
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    • 1999

  • Reactions of 2,6-Lutidine with active methyl group anilines in the presence of sulfur gave the desired thioamides 1. Reactions of synthesized thioamides 1 with sulfur and SiO2 or SeO2 gave the corresponding amide 2. We now report conversion of thioamide to amide by using oxidzing inorganic reagant

Ab-inito and NMR Studies on the Rotational Barrier for Thioacetamide and Acetamide

  • 최영기;송근일;최영상;윤창주
    • Bulletin of the Korean Chemical Society
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    • 제18권10호
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    • pp.1094-1099
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    • 1997

  • The rotational barriers of thioacetamide (TA) and acetamide (AA) were studied using the ab-initio molecular orbital theory and NMR spectroscopy. The calculated rotational barriers using MP2/6-31G**//MP2/6-31G** for TA was 72.26 kJ/mol and 58.19 kJ/mol for AA, respectively. These results are good agreement with the experimental data. The tendency for the change of structural parameters is consistent with the result of formamide. In both amides, the rotational barrier arises from the pyramidalization of nitrogen. The chemical shifts of both amides are shifted upfield when temperature is raised, which confirms pyramidalization of nitrogen. The lineshape of 1H-NMR spectra of TA shows quintet which is contributed from two triplet spectra. This means that the distribution of electrons around the nitrogen is rather symmetric. Ab-initio calculations of electric field gradient for both amides confirm the above results. The above experimental results are well understood by Keith's view on thioamides, which excludes the contribution of resonance structure and considers the origin of rotational barrier to be the same in both thioamides and in corresponding amides.

  • https://doi.org/10.5012/bkcs.1997.18.10.1094 인용 PDF

$CCl_4$속에서 Thioamides 와 Dimethyl Sulfoxide (DMSO) 사이의 수소 결합에 대한 연구 (Hydrogen Bonding between Thioamides and Dimethylsulfoxide (DMSO) in $CCl_4$)

  • 도영락;김선진;윤창주;최영상
    • 대한화학회지
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    • 제36권2호
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    • pp.185-190
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    • 1992

  • 사염화탄소 속에서 대단히 묽은 티오아미드 및 티오아미드-DMSO 용액의 $ν_{\alpha}$ + Amide II 조합띠에 대한 근적외선 스펙트럼을 $5^{\circ}C$ 와 $55^{\circ}C$ 사이에서 얻었다. 이 조합띠는 두 개의 Lorentzian-Gaussian product 함수로 분해되며, 각각은 단체 티오아미드 및 1 : 1 티오아미드-DMSO 복합체로 확인되었다. 티오아세트아미드(TA)와 DMSO 사이의 수소결합은 티오프로피온 아미드(TPA)와 DMSO 사이의 수소결합보다 약간 강하며 $CCl_4$ 속에서 TA-DMSO와 TPA-DMSO 1: 1 복합체에 대한 ${\Delta}H^{\circ}$는 각각 -15.3 kJ${\cdot}$$mol^{-1}$ 및 -14.2 kj${\cdot}$$mol^{-1}$이었다.

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