• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.467-471
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• 2016

Gallstones constitute one of the more common and relatively costly conditions of the gastrointestinal system and are a major risk factor for gallbladder cancer. Most gallstone cases involve individuals younger than 60 years of age, those older representing 9% of the total in one series. There are many risk factors for gallstones and Lith and Mucin genes, for example, play important roles in their formation. Surgery is one therapeutic approach but in the future it is to be expected that drugs for prevention of gallstones will be developed in the future. This will have clear implications for gallbladder cancer control.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2007년도 Proceedings of The Convention of The Korean Society of Applied Pharmacology
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• pp.15-22
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• 2007

Increasing evidence indicates that microglia-driven chronic inflammatory responses playa pathological role in the central nervous system. Activation of microglia is pivotal in the initiation and progression of neuroinflammation. Inhibition of the microglial activation may provide an effective therapeutic intervention that alleviates the progression of the neurodegenerative diseases. Anti-inflammatory agents may be a useful candidate for such a therapeutic approach. Continual investigation of the mechanisms underlying microglial activation and regulation of neuroinflammation by endogenous or exogenous factors would not only lead to the discovery of novel neuroprotective agents, but also help to understand complex pathophysiology of neurodegenerative diseases.

• 대한물리치료사협회지
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• 통권3호
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• pp.39-45
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• 1981

A Study on Scoliosis Milwaukee Brace , Therapeutic Exercise -Oh, Kuyung- Hwan Scoliosis implies an appreciable lateral deviation in the spine. There are numerous theories of the etiology of scolisosis. but the true causative factors remain unknown ;thus this affliction currently cannot be prevented. Treatment essentially consists of early recognition, correction of existing curves, and prevention of the further progression of the curves . Tremendous strides are being made in the treatment of severe scoliosis but the desire for early nonoperative treatment is of paramount important. Many conservative nonoperative procedures have been advocated. Among th-em .Milwaukee brace and therapeutic exercise are the most effective ones .

• The Journal of Korean Physical Therapy
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• 제11권2호
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• pp.131-137
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• 1999

Neurotrophic factors control the survival and differentiation in developing neurons, Furthermore, nut evidence suggests that neurotrophic factors promote the axonal growth and synaptic plasticity In the CNS. Research is currently being undertaken in order to determine whether members of the neurotrophic factor family have potential therapeutic roles in preventing and/or reducing the neuronal cell death and atrophy. This review summarizes the current knowledge of characterized neurotrophic factors including NGF, BDNF, NT-3, and NT-4/5.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1081-1091
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• 2012

Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematologic neoplasms characterized by morphologic dysplasia, aberrant hematopoiesis and peripheral blood refractory cytopenias. MDS is recognized to be associated with an increased risk of symptomatic anemia, infectious complications and bleeding diathesis, as well as a risk of progression to acute myeloid leukemia, particularly in patients with a high IPSS score. The advent of use of hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) and recombinant erythropoietin (EPO) has improved symptoms in MDS patients in addition to some data that suggest there might be an improvement in survival. G-CSF is an effective therapeutic option in MDS patients, and it should be considered for the management of refractory symptomatic cytopenias. G-CSF and EPO in combination can improve outcomes in appropriate MDS patients such as those with lower-risk MDS and refractory anemia with ring sideroblasts (RARS). This article reviews use of growth factors for lower-risk MDS patients, and examines the data for G-CSF, EPO and thrombopietic growth factors (TPO) that are available or being developed as therapeutic modalities for this challenging disease.

• 보건의료산업학회지
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• 제14권1호
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• pp.15-30
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• 2020

Objectives: This study investigated outpatient health care satisfaction and influential factors using data from the "2018 Health Care Experience Survey". Methods: Data on 6,705 participants in the Health Care Experience Survey were statistically examined using a t-test, ANOVA, and multiple regression analysis. Results: First, the level of satisfaction among outpatients was generally positive, and satisfaction among older people was high. Second, the significant factors of outpatient overall satisfaction were gender, consultation time, waiting time, reason for choosing institution, satisfaction with doctors, nurses, institutions, and the therapeutic result. Third, influential factors of intention to recommend were education, institution type, reason for choosing institution, satisfaction with doctors, nurses, institutions, and the therapeutic result. Conclusions: In order to improve the overall satisfaction of outpatients, the treatment method should be improved. For example, the doctor should devote more time for and engage in sufficient conversation with the patient, the nurse should be polite, and patients should be given easy-to-understand explanations.

• 대한물리치료과학회지
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• 제16권3호
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• pp.67-74
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• 2009

Background: Various functional factors should be incorporated during assessment and intervention for patient rehabilitation. Stable respiratory function is one of required factors for functional restoration. To maximize respiratory physical therapy intervention outcome, it is required to understand clinical features of respiratory diseases and physical therapy approaches. Methods: Previous studies were systematically reviewed through computerized search. Methodological qualities of selected studies were evaluated and the levels of recommendations were determined. Results: Assessment for respiratory pattern and thoracic mobility is of importance to improve cardiopulmonary fitness during physical reconditioning. Application of optimal therapeutic protocol can increase thoracic mobility and respiratory function. Interdisciplinary communication is critical during rehabilitation for respiratory patients. Health care provider should have professional knowledge and experience for cardiopulmonary fitness and obligation to endeavor for patients' respiratory rehabilitation. It is necessary to standardize therapeutic intervention, and rehabilitative respiratory exercise should be applied to confirm the effects of intervention. Conclusion: Respiratory diseases that may reduce patients' quality of life and cardiopulmonary fitness should be resolved through physical therapy approaches. Through conducting research, effect of evidence-based and patients' function-oriented intervention can be determined.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1885-1887
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• 2014

Skin metastases of breast cancer are usually late events in the course of tumor progression and signify a poor prognosis. They may remain as a therapeutic challenge especially after failure of standard treatments. Topical interventions, together with or without radiotherapy, may only palliate the symptoms temporarily. However, there may be alternative treatment modalities for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy. There are various genetic alterations in tumors and therapeutic potential of expression patterns for factors like epidermal growth factor receptor may have important clinical implications in case of disease refractory to the conventional treatments. Here, we clarified the therapeutic options and genetic alterations in skin metastatic breast cancer patients refractory to standard chemotherapeutics.

• 정신신체의학
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• 제3권2호
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• pp.222-231
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• 1995

The author reported a case of short-term dynamic psychotherapy in which relatively good therapeutic results were obtained. And I reviewed several therapeutic factors thought to be important in shot-term dynamic psychotherapy from various literatures. In this case, the frequency of session was limited due to her current reality situations. She had suffered from some adjustmental problems and marital conflict before the onset of the illness. The author could grasp the cental theme of her problems early in treatment period and discussed over it including it's influence on current situation and early childhood with th patient. We also discussed about the relationship between the past and current reality so that she could realize her real problem. At the same time, therapeutic effect was enhanced by family therapy and temporary use of medication.

• Radiation Oncology Journal
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• 제7권2호
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• pp.185-188
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• 1989

Radiation treatment results were analyzed in a retrospective analysis of 47 patients with pituitary adenoma treated with radiation alone or combined with surgery from 1974 through 1987 at the Department of Therapeutic Radiology of Kyung Hee University. The 5-year overall survival rates for all patients was $80.4\%$ Radiation therapy was effective for improving visual symptoms and headache, but could not normalize amenorrhea and galactorrhea. There was no difference of survival rate between radiation alone and combination with surgery. Prognostic factors such as age, sex, disease type, visual field, headache and surgical treatment were statistically no significant in survival rates of these patients.