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A Delphi Study on National Public Vaccine Research and Development Policy in Korea (델파이기법을 활용한 국가 공공(公共)백신 연구개발 정책수립 기초조사)

  • Lee, Somin;Yeo, Sang-Gu;Kang, Shin Jung;Han, Soon Young;Lee, Sang-Won
    • Health Policy and Management
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    • v.25 no.2
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    • pp.140-148
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    • 2015
  • Vaccination is the most powerful and useful preparation against infectious diseases. However, developing vaccines costs a lot and requires extensive long-term efforts. Therefore, the government should research and develop vaccines with a national-level policy. To greatly enhance the success rate of vaccine development, the policy should be set up considering priorities such as the current status of domestic research, the importance for public health, the urgency of research. The Delphi technique was utilized to draft this survey, through a brainstorming stage, then two inquiries, and finally the final panel meeting where unresolved items were discussed, to draw the conclusion. Among the results, firstly, the highest ranked item on centralized fields for vaccine development by the Ministry of Health was 'self-sufficiency of vaccines.' Secondly, 'emerging infectious disease' was most highly ranked in prioritized fields of vaccine development and research. Thirdly, for the vaccine that needs to be improved and developed further by the government to improve its efficacy and safety, BCG (Bacille de Calmette) for tuberculosis was ranked the highest on both types (intradermal and subcutaneous injection) from National Immunization Programme (NIP) and non-NIP. As for the high risk pathogens, 'anthrax' and 'smallpox' were first and second, consecutively. Lastly, 'development and control of vaccine candidates' was ranked the highest for the area in need for technique development in order to improve domestic vaccine's research level. The results of this study will be put to good use as basic data for the national vaccine research and development (R&D) policy of the country. This study was first step and more studies should be carried out for the final decision of the national vaccine R&D priority.

Development of the Concept of Object Permanence in Infancy (유아의 물체영속성개념 발달에 관한 실험연구)

  • Park, Kyung Ja
    • Korean Journal of Child Studies
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    • v.2
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    • pp.1-16
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    • 1981
  • This study had two purposes. First, to examine the stages and developmental order of object permanence based on Piaget's theory. Second, to assess the effects of delay, attentiveness, and direction of gaze. Two experiments were conducted to examine the object permanence development in infants. The subjects for the 2 experiments were randomly drawn from a well-baby clinic. The subjects for Experiment 1 were 72 infants, 12 each in 6 age levels : 6, 9, 12, 15, 18, and 21 months old. Experiment 1 was designed to examine the stages and developmental order of object concept development, ana infants received 5 tasks as follows : (1) finding an object partially hidden under one box (2) finding an object completely hidden under one box (3) finding an object after successive visible displacements (4) finding an object after one invisible displacement (5) finding an object after successive invisible displacements. The subjects for Experiment 2 were 24 9-month-olds. Experiment 2 was designed to assess the effects of delay, attentiveness, and direction of gaze for Stage IV of object concept development. Subjects were equally assigned into one of two delay groups: 0-sec delay and 3-sec delay. Attentiveness was rated in terms of a three-point scale, and then divided into high and low attentive groups. Direction of gaze was judged into two directions. In two experiments, infants received three trials of task, and received a score of 0, 1, 2 for each trials. Data were analyzed by ANOVA, Tukey test, and t-test for task performance, and direction of gaze was analyzed by chi-square. The results obtained from two experiments were as follows : 1. In object permanence test, subjects obtained significantly higher scores with age, and 6, 9, 12, 18 months were classified into different developmental stages. 2. In object permanence development, subjects received significantly different scores with task and a developmental order of tasks was found. First of all, infants mastered finding an object partially hidden under one box, and then mastered finding an object completely hidden under one box. Contrary to Piagetian theory, in this study, the development of finding an object after successive visible displacements and finding an object after one invisible displacement were sometimes reversed. Finally, finding an object after successive invisible displacements was mastered, and the concept of object permanence was completed. 3. In Stage IV of object concept development, a 3-sec delay did not significantly affect the performance of tasks. The O-sec delay group didn't perform significantly better than the 3-sec delay group. 4. In Stage IV of object concept development, attentiveness of infants significantly affected the performance of task. So the highly attentive infants obtained better performance scores than the low attentive infants. 5. In Stage IV of object concept development, direction of gaze significantly affected the performance of task. That is, infants who gazed at the box which contained the object showed a higher rate of success than infants who gazed at the box which had already displaced the object.

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Construction of Precise Mine Geospatial Information and Ore Modeling for Smart Mining (스마트마이닝을 위한 정밀 광산공간정보 구축 및 광체 모델링)

  • Park, Joon Kyu;Jung, Kap Yong
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.38 no.6
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    • pp.725-731
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    • 2020
  • In mineral resource development, resource exploration is a task to find economical minerals on the surface and underground, and the success rate is low compared to the development and production stages, and it is necessary to collect a lot of data through exploration and accurately analyze the collected information. In this study, mine spatial information was constructed using a 3D (Three-dimensional) laser scanner, and accuracy evaluation was performed to obtain a maximum deviation of 0.140 m and an average of 0.095 m in the X, Y and Z directions, and the possibility of utilizing the construction of mine geospatial information through a 3D laser scanner could be presented. In addition, the ore body modeling was performed by applying the interpolation method of the ore body section using the resource exploration results. The ore body modeling result was superimposed with the modeling result of the mine geospatial information built through the 3D laser scanner to construct the ore body modeling result based on the precise mine geospatial information. The results of ore body modeling based on mine geospatial information built through research can increase the ease of data interpretation and the accuracy of the calculated data, which will greatly increase the efficiency of work related to mineral resource development and mine damage prevention in the future.

A Study on the Competition of the World Women's Handball Championship Using Bigdata : Focused on the top 5 teams of the 2007-2019 World Women's Handball Championship (빅데이터를 활용한 여자핸드볼선수권대회 전력 비교 연구 -2007~2019년 세계여자핸드볼선수권대회 상위 5개팀과 대한민국을 중심으로-)

  • Kang, Yong-Gu;Kwak, Han-Pyong
    • Journal of Industrial Convergence
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    • v.19 no.1
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    • pp.147-158
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    • 2021
  • This study was conducted seven times from 2007 to the 2019 Women's World Handball Championships to analyze and strengthen the strength of the Korean women's handball team through the analysis of the top five countries' strengths. Among the 41 national teams participating in the World Women's Handball Championship, a total of five national teams, including the Netherlands, Norway, Russia, Spain, and France, were selected for the final study. Among the records provided by the International Handball Federation (IHF), the ranking was selected by analyzing the competition records of 41 participating countries, and technical statistics and frequency analysis were conducted using the SPSS/PC+ Ver21.0 program. based on the accumulated records of the top five women's handball competitions, handball attack and defense strategies that can make up for the inferiority in future physical conditions are needed and detailed follow-up studies are needed. Also, we hope to use it as a basic resource for improving the performance of Korean women's handball players and to play a key role in enhancing the level of women's handball at the 2021 Tokyo Olympics.

A Study on the Background of Start-Ups and the Factors of Entrepreneurship in Young Job Seekers' Willingness to Start a Business: Verification of the Mediating Effect of Perception of Businessmen (청년구직자의 창업 배경과 기업가정신이 창업 의지에 미치는 요인에 관한 연구: 사업가에 대한 인식의 매개 효과 검증)

  • Oh, Hee Shun;Ha, Kyu Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.16 no.3
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    • pp.87-103
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    • 2021
  • The government is trying to create jobs by providing 160 billion won in 2021 to revitalize youth start-ups, but the number of youth unemployment and potential unemployment is hitting a record high of 1.2 million due to the shock of employment due to COVID-19. Although start-ups are encouraged as an alternative to revitalizing jobs, the success rate of young start-ups is low due to lack of start-up funds and experience. The purpose of this study is to understand the need to diversify start-up education and career education by understanding start-up policies through one-time funding and short-term education. The results of the study on the factors affecting the willingness to start a business were as follows, by sampling 344 students from specialized high schools preparing for employment and 344 young people in their 20s who are seeking jobs. First, among the entrepreneurship subvariables, innovation, autonomy of job value, and desire for economic achievement are significant, and the older the person surveyed, the more positive the perception of the entrepreneur was. Second, as you get older, your will to start a business decreases, and your experience in successful start-up models and start-up education has an impact on your will to start a business. Third, perception of entrepreneurs is a partial medium effect, which indirectly influences the willingness to start a business and directly or indirectly influences the willingness to start a business through the autonomy of job values, the desire to achieve economic and entrepreneurship.

Distributed Construction of the Recrystallization Topology and Efficient Searching in the Unstructured Peer-to-Peer Network (재결정 위상의 분산적 구성과 비구조적 피어투피어 망에서의 효율적 검색)

  • Park, Jae-Hyun
    • Journal of KIISE:Information Networking
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    • v.35 no.4
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    • pp.251-267
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    • 2008
  • In this paper, we present a distributed topology control algorithm for constructing an optimized topology having a minimal search-time in unstructured peer-to-peer network. According to the proposed algorithm, each node selects the best nodes having higher hit-ratio than other nodes as many as the number being exponentially proportional to the hit-ratio of the node itself, and then it connects to them. The ensemble behavior of the proposed algorithm is very similar to the recrystrallizing phenomenon that is observed in nature. There is a partial order relationship among the hit-ratios of most nodes of constructed topology. Therefore once query message visits a node, it has a higher hit-ratio than the node that was visited last by the message. The query message even sent from freeloader can escape to the node having high hit-ratio by one hop forwarding, and it never revisits any freeloader again. Thus the search can be completed within a limited search time. We also propose the Chain-reactive search scheme using the constructed topology. Such a controlled multicasting reduces the query messages by 43 percent compared to that of the naive Gnutella using broadcasting, while it saves the search time by 94 percent. The search success rate of the proposed scheme is 99 percent.

Hazardous Health Behaviour among Medical Students: a Study from Turkey

  • Nacar, Melis;Cetinkaya, Fevziye;Baykan, Zeynep;Yilmazel, Gulay;Elmali, Ferhan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7675-7681
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    • 2015
  • Background: Hazardous health behaviour in young people is an important factor that affects the individual risk for non-communicable diseases and other disorders later in life. This study aimed to determine the hazardous health behaviour of first and last class medical students of Erciyes University. Materials and Methods: This descriptive study was carried out with 240 medical students from the first and 130 students from the last (sixth) class. Data were obtained by questionnaire between March-April 2012. In total, 339 students were included with a response rate of 91.6%. Socio-demographic characteristics, school success, self-reported economic difficulties, health perceptions, hazardous health behaviour related to chronic disease, tobacco, alcohol, substance use, body weight, height, traffic, violence and nutrition were assessed in line with the literature. Results: Of the participants; 64.0% were from first and 36.0% were from the last class. Mean ages for the first and last classes were $19.4{\pm}1.5$ and $24.0{\pm}1.5years$, respectively. In the current study, males exhibited more hazardous behaviour than females. Sime 19.8% of the students in the study group used alcohol, 35.4% used a waterpipe, and 24.8% used tobacco at least once. These rates increased in both genders in the last class and the increase in males was significant. Some 3.8% of the students in the current study used pleasure-inducing illegal substances at least once. All the students participating in the current study were single, the number of males reported not using condoms (8.6%) was 4.56 times higher compared to females. Some 64.0% of the students did not perform physical activity lasting at least 30 minutes for five times a week, 13.0% did not sleep for mean 7-8 hours daily, males having a 2.9 times higher risk. More than 1/3 of the students did not consume cooked vegetable dishes and 1/4 did not consume fresh fruits and salads, the rates were higher among males. Conclusions: In the current study, hazardous health behaviour was prevalent among medical students, with higher risks among males and last class students. According to these results, medical curriculum may be focused on decreasing hazardous health behaviour. In addition, in order to prevent unhealthy behaviour, the number of youth-friendly health facilities should be increased.

Auto-Segmentation Algorithm For Liver-Vessel From Abdominal MDCT Image (복부 MDCT 영상으로부터 간혈관 자동 추출 알고리즘)

  • Park, Seong-Me;Lee, You-Jin;Park, Jong-Won
    • Journal of Korea Multimedia Society
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    • v.13 no.3
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    • pp.430-437
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    • 2010
  • It is essential for living donor liver transplantation that surgeon must understand the hepatic vessel structure to improve the success rate of operation. In this paper, we extract the liver boundary without other surrounding structures such as heart, stomach, and spleen using the contrast enhanced MDCT liver image sequence. After that, we extract the major hepatic veins (left, middle, right hepatic vein) with morphological filter after review the basic structure of hepatic vessel which reside in segmented liver image region. The purpose of this study is provide the overall status of transplantation operation with size estimation of resection part which is dissected along with the middle hepatic vein. The method of liver extraction is as follows: firstly, we get rid of background and muscle layer with gray level distribution ratio from sampling process. secondly, the coincident images match with unit mesh image are unified with resulted image using the corse coordinate of liver and body. thirdly, we extract the final liver image after expanding and region filling. Using the segmented liver images, we extract the hepatic vessels with morphological filter and reversed the major hepatic vessels only with a results of ascending order of vessel size. The 3D reconstructed views of hepatic vessel are generated after applying the interpolation to provide the smooth view. These 3D view are used to estimate the dissection line after identify the middle hepatic vein. Finally, the volume of resection region is calculated and we can identify the possibility of successful transplantation operation.

Gabor Wavelet Analysis for Face Recognition in Medical Asset Protection (의료자산보호에서 얼굴인식을 위한 가보 웨이블릿 분석)

  • Jun, In-Ja;Chung, Kyung-Yong;Lee, Young-Ho
    • The Journal of the Korea Contents Association
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    • v.11 no.11
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    • pp.10-18
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    • 2011
  • Medical asset protection is important in each medical institution especially because of the law on private medical record protection and face recognition for this protection is one of the most interesting and challenging problems. In recognizing human faces, the distortion of face images can be caused by the change of pose, illumination, expressions and scale. It is difficult to recognize faces due to the locations of lights and the directions of lights. In order to overcome those problems, this paper presents an analysis of coefficients of Gabor wavelets, kernel decision, feature point, size of kernel, for face recognition in CCTV surveillance. The proposed method consists of analyses. The first analysis is to select of the kernel from images, the second is an coefficient analysis for kernel sizes and the last is the measure of changes in garbo kernel sizes according to the change of image sizes. Face recognitions are processed using the coefficients of experiment results and success rate is 97.3%. Ultimately, this paper suggests empirical application to verify the adequacy and the validity with the proposed method. Accordingly, the satisfaction and the quality of services will be improved in the face recognition area.

Analysis of the Prognostic Factors in Trauma Patients with Massive Bleeding (외상으로 인한 대량 출혈 환자에서의 예후인자 분석)

  • Choi, Seok Ho;Suh, Gil Joon;Kim, Yeong Cheol;Kwon, Woon Yong;Han, Kook Nam;Lee, Kyoung Hak;Lee, Soo Eon;Go, Seung Je
    • Journal of Trauma and Injury
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    • v.25 no.4
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    • pp.247-253
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    • 2012
  • Purpose: Hemorrhage is a main cause of death in trauma patients. The goal of this study is to describe the characteristics of trauma patients with massive bleeding and to evaluate the prognostic factors concerning their survival. Methods: This study was performed retrospectively and included trauma patients with massive bleeding who had been treated from March 2007 to August 2012. The inclusion criterion was patients who received more than 10 U of packed red blood cells within the first 24 hours after visiting the emergency department. Based on their medical records, we collected data in terms of demographic findings, mechanisms of injury, initial clinical and laboratory findings, methods for hemostasis (emergency surgery and/or angioembolization), transfusion, injury severity score (ISS), revised trauma score (RTS) and trauma and injury severity score (TRISS). We used the Mann-Whitney U test and Fisher's exact test to compare the variables between the patients that survived and those that did not. We performed a logistic regression analysis with the significant variables from the univariate test. Results: Thirty-two(32) patients were enrolled. The main mechanisms of injury were falls and motor vehicle accidents. The mean transfusion amount of packed red blood cells (PRBC) was 17.4 U. The mean elapsed time for the first hemostasis (surgery or embolization) was 3.5 hours. The initial technical success rates were 83.3%(15/18) in angioembolization and 66.7%(8/12) in surgery. The overall mortality rate was 34.4%(11/32). The causes of death were bleeding, brain swelling and multiple organ failure. The ISS(25.5 vs 46.3, p=0.000), TRISS(73.6 vs 45.1, p=0.034) and base excess(<-12 mmol/L, p=0.020) were significantly different between the patients who survived and those who did not. Conclusion: The ISS was a prognostic factor for trauma patients with massive bleeding.