• BMB Reports
• /
• 제43권9호
• /
• pp.629-634
• /
• 2010

Endotoxin including lipopolysaccharide (LPS) confers organ tolerance against subsequent challenge by ischemia and reperfusion (I/R) insult. The mechanisms underlying this powerful adaptive defense remain to be defined. Therefore, in this study we attempted to determine whether nitric oxide (NO) and its associated enzymes, inducible NOS (iNOS) and endothelial NOS (eNOS, a constitutive NOS), are associated with LPS-induced renal tolerance against I/R injury, using iNOS (iNOS knock-out) or eNOS (eNOS knock-out) gene-deleted mice. A systemic low dose of LPS pretreatment protected kidney against I/R injury. LPS treatment increased the activity and expression of iNOS, but not eNOS, in kidney tissue. LPS pretreatment in iNOS, but not eNOS, knock-out mice did not protect kidney against I/R injury. In conclusion, the kidney tolerance to I/R injury conferred by pretreatment with LPS is mediated by increased expression and activation of iNOS.

• 한국조경학회지
• /
• 제40권6호
• /
• pp.70-78
• /
• 2012

경주 동궁과 월지의 생태적 수용력 연구를 위해 유적지내에서 관찰되어지는 7가지 이용행태에 따른 이용구간별 녹지 평균손상도를 산정하였다. 이를 위해 탐방객 이용행태의 이용인수 및 이용시간을 조사하고 손상도를 산정하였다. 각 이용행태별 손상도를 통하여 4가지 조사구의 적정수용력, 표준수용력과 한계수용력을 명확하게 파악할 수 있다. 각 조사구의 이용행태별 이용인수 및 이용시간에 따른 손상도를 산정한 결과, '걷다'의 경우 평균 2.15로 가장 높았고, '눕다'의 경우 0.05로 가장 낮은 것으로 나타났다. 그리고 각 조사구의 손상도는 조사구 4가 1.31로 가장 높았고, 조사구 3이 0.97, 조사구 1이 0.91, 조사구 2가 0.70의 순으로 나타났다. 각 조사구의 손상면적을 산정 후에 생태적 수용력을 추정한 결과, 조사구1, 2, 3, 4의 적정수용력은 각각 40인, 249인, 107인, 37인, 한계수용력은 각각 116인, 713인, 306인, 107인, 표준수용력은 각각 75인, 463인, 198인, 69인으로 추정된다. 경주 동궁과 월지의 바람직한 관리를 위한 최대의 생태적 수용력은 한계수용력 이하로 하는 것이 적합하다.

• International Journal of Safety
• /
• 제6권1호
• /
• pp.1-6
• /
• 2007

Operation of human-centered robot, in general, facilitates the creation of new process that may potentially harm the human operators. Design of safety-guaranteed operation of human-centered robots is, therefore, important since it determines the ultimate outcomes of operations involving safety of human operators. This study discusses the application of geometric tolerance and head injury criteria to safety assessment of human-centered robotic operations. Examples show that extending "Work Area" has more significant effect on the uncertainty in safety than extending the system range in the presence of velocity control.

• 한국환경복원기술학회지
• /
• 제18권2호
• /
• pp.45-52
• /
• 2015

Cool-season turfgrass is a rapidly increasing of usage for the revegetation of waterside slopes in dams, lakes and rivers. The purpose of this research is to identify the flooding tolerance of cool-season turfgrass with respect to the flooding periods of 0(control), 2, 4 and 6 days, respectively. The surface coverage ratio, turfgrass injury and soil moisture content were measured to assess the flooding tolerance of cool-season turfgrass. The increase in the flooding periods with 4 and 6 days resulted in the lower surface coverage ratio for cool-season turfgrass while no significant difference was found in the 2 days flooding when compared to 0 day (the control plot) flooding plot. In case of the turfgrass injury and the soil moisture content, however, the higher values were found with the increase of flooding periods in 2, 4 to 6 days. We observed that the higher the turfgrass injury and soil moisture content increased, the lower the surface covrage ratio decreased. In these regards, we also observed that the tolerance of cool season turfgrass were high in the 2 days flooding condition, medium in the 4 days flooding condition and low in the 6 days flooding condition. The flooding tolerance of cool-season turfgrass was gradually weakened in over 2 days flooding periods due to $O_2$ deficiency in the anaerobic soil condition. Therefore, we could suggest cool-season turfgrass within 2 days flooding periods for the revegetation of waterside slopes in dams, lakes and rivers.

• 한국환경농학회지
• /
• 제15권4호
• /
• pp.479-487
• /
• 1996

$SO_2$에 대한 양버즘나무의 내성을 증대시키고자 생장왜화제인 uniconazole을 토양주입하고, 그 내성 기작을 superoxide dismutase와 peroxidase의 역할과 관련하여 조사했던 바 다음과 같은 결과를 얻었다. Uniconazole은 농도가 높아질 수록 간장, 엽면적 및 T/R율(率)을 현저하게 감소시키고, 엽록소 농도와 superoxide dismutase 및 peroxidase활성을 현저하게 증가시켜 $SO_2$ 처리에 의한 가시피해를 유의성있게 경감시켰다. Diethyldithiocarbamate를 엽면살포하였을때, superoxide dismutase와 peroxidase 활성이 현저하게 불활성화되어 $SO_2$ 처리에 의한 가시피해(可視被害)가 증가되었으며 uniconazole 처리에 의해 증대되었던 $SO_2$ 내성은 diethyldithiocabamate 처리에 의하여 다시 감소되었다. 이상과 같이 uniconazole은 식물생장의 왜화(矮化)에 의한 조직의 치밀화 이외에 SOD와 POD의 활성증대를 통해 $SO_2$에 대한 내성을 증대시킨 것으로 판단된다.

• 자동차안전학회지
• /
• 제6권2호
• /
• pp.43-48
• /
• 2014

The flexible pedestrian legform impactor(Flex-PLI) consisting of a flexible femur and tibia will be tested for pedestrian protection by global technical regulation(GTR) within the next couple of years as a replacement for the existing transport research laboratory(TRL) legform impactor. In this study, a computer aided engineering(CAE) model was used to perform the effect analysis of each injury with regard to the changes in tolerance factors with the baseline results without tolerance. The tolerance factors were the height of impactor from ground reference line, initial velocity of impactor and rotation of impactor.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제18권1호
• /
• pp.1-8
• /
• 2018

In recent years, with continuous research efforts targeted at studying the effects of pre- and after-treatment of inhaled anesthetics, significant progress has been made regarding the common clinical use of low concentrations of inhaled sevoflurane and its effect on induced central ischemia tolerance by pre- and post-treatment. In this study, we collected, analyzed, classified, and summarized recent literature regarding the effect of sevoflurane on central ischemia tolerance and its related mechanisms. In addition, we provide a theoretical basis for the clinical application of sevoflurane to protect the central nervous system and other important organs against ischemic injury.

• 한국조경학회지
• /
• 제22권1호
• /
• pp.101-110
• /
• 1994

A field study was carried out to investigate the visual injury of zoysiagrass and creeping bentgrass by the application of various herbicides the result were as follows. 1. Trifluralin + benefin and dithiopyr did not injure creeping bentgrass and zoysiagrass. 2. Creeping bentgrass was safe while zoysiagrass was slightly injured within acceptable level with benefin. 3. Oryzalin caused injury both on creeping bentgrass and zoysiagrass. However, the injury of zoysigrass was within acceptable level while the injury of creeping bentgrass increased without acceptable level when applied at>5kg/ha. 4. Creeping bentgrass was tolerant to pendimethalin only when treated at<3.4kg/ha whereas zoysiagrass was tolerant regardless of rate. 5. Creeping bentgrass treated with fenoxaprop, oxadiazon, and bensulide were severely injured. However, turfgrasses treated with bensulide recovered rapidly when compared with fenoxaprop and oxadiazon. 6. Zoysiagrass treated with 2,4-D, dicambe, bentazon was safe when applied at mid summer.

• 한국작물학회지
• /
• 제48권6호
• /
• pp.516-526
• /
• 2003

본 실험은 한국 재배종과 재래 수집종을 포함하는 36개 보리 품종을 공시하여 비가림 플라스틱 하우스의 포장 조건에서 실시하였다 대조구는 전 생유기간에 걸쳐서 토양 수분 포텐셜이 -0.05㎫이 유지되도록 관개를 하였고, 한발 처리구는 월동 후 재생기부터 수확기까지 곤개를 하지 않았다. 한발 처리구의 토양 수분 포텐셜은 최저 -0.29㎫까지 저하하였고 처리기간 중 평균은 -0.15㎫이었다. 처리에에 따른 생장, 수량 및 수량구성요소, 잎의 상대수분함량(RWC), 삼투포텐설(OP), 삼투조정(OA), $^{13}\textrm{C}$ discrimination(A), 등의 변화를 조사하여 다음과 같은 결과를 얻었다. 1. 공시한 품종 중 한발 처리에 따른 건물 중과 수량 저하 가 작아서 한발 저항성이 강한 품종은 동보리1호. 찰보리, 창영재래, 삼도보리, 월성87-31 등이었으며, 상록보리 , 송학보리, 수원맥360 등은 한발저항성이 낮았다. 2. 건물중 및 수량의 한발피해지수(한발처리구/대조구 비)와 한발조건하 RWC와는 높은 정의 상관이, 한발조건하 OP 및 OA는 매우 높은 부의 상관관계가 있었으며, 대조구의 $\Delta$와는 유의한 정의 상관관계가 있었다. 3. OP $\Delta$ 및 RWC의 한발지수(한발처리구/대조구 비)는 건물중, 천립중 및 수량의 한발피해지수와 매우 높은 정의 상관 관계를 나타내었다. 4. 이상의 결과를 종합해 보면 한발 저항성이 큰 품종은 삼투 조정능력이 커서 잎의 수분함량을 높게 유지하는 특성을 가지고 있어서 한발 처리 조건에서 OP와 RWC는 보리의 한발저항성 선발지표로 이용될 수 있을 것으로 판단되었다. 그러나 $\Delta$와 한발 저항성간의 관계에 대해서는 보다 구체적인 연구가 필요한 것으로 생각된다.

• 식물조직배양학회지
• /
• 제27권4호
• /
• pp.339-343
• /
• 2000

When plants are exposed to subfreezing temperatures ice crystals are forming within extracelluar space in leaves. The growth of ice crystal is closely related to the degree of freezing injury. It was shown that an antifreeze protein binds to an ice nucleator through hydrogen bonds to prevent growth of ice crystal and also reduces freezing damage. The antifreeze proteins in plants are similar to PR proteins but only the PR proteins induced upon cold acclimation were shown to have dual functions in antifreezing as well as antifungal activities. Three of the genes encoded for CLP, GLP, and TLP were isolated from barley and Kentucky bluegrass based on amino acid sequence revealed after purification and low temperature-inducibility as shown in analysis of the protein. The deduced amino acid of the genes cloned showed a signal for secretion into extracellular space where the antifreezing activity sup-posed to work. The western analysis using the antisera raised against the antifreeze proteins showed a positive correlation between the amount of the protein and the level of freeze tolerance among different cultivars of barely. Besides it was revealed that TLP is responsible for a freeze tolerance induced by a treatment of trinexapac ethyl in Kentucky bluegrass. Analysis of an overwintering wild rice, Oryza rufipogon also showed that an acquisition of freeze tolerance relied on accumulation of the protein similar to CLP. The more direct evidence for the role of CLP in freeze tolerance was made with the analysis of the transgenic tobacco showing extracellular accumulation of CLP and enhanced freeze tolerance measured by amount of ion leakage and rate of photosynthetic electron transport upon freezing. These antifreeze proteins genes will be good candidates for transformation into crops such as lettuce and strawberry to develop into the new crops capable of freeze-storage and such as rose and grape to enhance a freeze tolerance for a safe survival during winter.