• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1903-1907
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• 2016

Background: Studies of effects of IL-1 polymorphisms, CYP2C19 genotype together with antibiotic resistance for H. pylori eradication are rare worldwide. The present study was designed to evaluate efficacy of 10-day sequential therapy (SQT) and 14-day standard triple therapy (STT) with four- times-daily dosing of amoxicillin for H. pylori eradication related to these important host and bacterial factors in Thailand. Materials and Methods: This prospective randomized study was performed during March 2015 to January 2016. H. pylori infected gastritis patients were randomized to receive 10-day sequential therapy and 14-day standard triple therapy. CYP2C19 genotyping, IL1 polymorphism (IL-1B and IL-1RN genotypes) and antibiotic susceptibility tests were performed in all patients. 13C-UBT was conducted to confirm H. pylori eradication at least 4 weeks after treatment. Results: A total of 100 patients (33 males and 67 females, mean age=51.1 years) were enrolled. Eradication rate by PP analysis was 97.9% (47/48) with the 10-day SQT regimen and 87.8% (43/49) with 14-day STT regimen (97.9% vs 87.8%; p-value=0.053). Antibiotic susceptibility testing demonstrated 45% resistance to metronidazole, 14.8% to clarithromycin, and 24.1% to levofloxacin. CYP2C19 genotyping revealed 44.9% RM, 49% IM and 6.1% PM. IL-1B and IL-1RN genotypes were demonstrated as 21.4% for CC, 48.1% for TC, 36.8% for TT, 72.7% for 1/1, and 21.2% for 1/2 genotypes, respectively. The 10-day SQT regimen provided 100% eradication in patients with clarithromycin or dual clarithromycin and levofloxacin H. pylori resistant strains. Moreover, the 10-day SQT regimen resulted in a 100% eradication rate in all patients with CYP2C19 genotype RM and almost type of IL-1B (TC and TT) and IL1-RN genotypes ( 1/2 and other). Conclusions: Treatment with 10-day sequential therapy is highly effective for H. pylori eradication regardless of the effects of clarithromycin resistance, dual clarithromycin and levofloxacin resistance, CYP2C19 genotype, IL-1B and IL1-RN genetic polymorphisms and can be used as effective first line therapy in Thailand.

• The monthly packaging world
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• s.270
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• pp.100-110
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• 2015

본 고는 "재활용이 가능한 고차단성 폴리올레핀 유니 소재를 활용하여 온실가스를 감축하는 친환경식품포장 개발" 프로젝트의 일환으로 "태국의 식품포장산업 조사"를 토대하여 편집한 것이며, 태국 카쎄싸국립대학교 포장재료기술학과가 태국의 식품포장산업의 현황 및 동향을 파악하여 태국의 식품포장에 주로 사용되는 유리, 플라스틱, 종이 등 주요 포장재료에 관한 정보를 얻는 데 있다. 이 자료에서는 가능한 연성 및 경성의 플라스틱포장, 종이포장, 유리포장의 생산현황을 담고 있다. 또한 포장용기의 생산량 및 추이가 태국 전역 및 주 생산 지역 전반의 차원에서 다루어지고 있으며, 포장 재료간 경쟁력도 언급한다. 제공하는 자료들은 현장조사, 설문, 인터뷰, 각종 서신, 그리고 각종 출판 자료를 바탕으로 한 것이다. 요약하면, 생산량을 기준으로 보면 주요 식품포장 재료들 중 종이, 플라스틱, 유리, 금속의 순으로 사용되었다. 종이용기 중에서는 골판지 용기가 여타 형태의 종이용기보다 많이 생산되었다. 플라스틱 포장에 있어서는 플라스틱 병과 유연성 파우치의 두 형태가 돋보였는데, 이는 대부분 음료업계에서 사용된다. 유리병도 태국의 음료업계에서 주로 사용되는데, 특히 재활용 용기로 활용된다. 지난 10년간 금속용기는 유연성 파우치와 아셉틱 카톤 팩으로 대체되어 생산량이 대폭 줄었다. 본 고에서는 한국식품연구원 박형우 책임연구원의 자료 제공을 바탕으로 총 3~4회에 걸쳐 태국 포장산업 실태에 대해 살펴보도록 한다.

• East Asian Economic Review
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• v.20 no.3
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• pp.391-423
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• 2016

By examining the relationship between private credit growth and the possibility of credit risk while focusing on international capital in 21 countries over the period 2000:1Q-2015:2Q, this paper shows that the impact of private credit growth on credit risk is apparent under the high ratio of capital inflows, and its impact on credit risk in the seven Asian countries is even stronger. And the possibility of credit risk caused by private credit is mainly coming from portfolio inflows rather than direct inflows. Finally, portfolio inflows strengthen the positive relationship between credit excess and credit risk in Asian countries, and this trend is seen more in these after the global financial crisis. Taken together, the stronger positive relationship between credit excess and credit risk can be strengthen under the massive portfolio inflows in particular in the seven Asian countries such as Hong Kong, India, Indonesia, Korea, Malaysia, Singapore, and Thailand.

• Asia-Pacific Journal of Business
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• v.6 no.2
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• pp.35-61
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• 2015

This study deals how employees' perceptions of being supported by their organizations and supervisors may lead to organizational commitment and this commitment affects turnover intention and organizational citizenship behavior in the context of Thai industrial firms. The sample consists of Thai employees working in manufacturing firms which Koreans operate in Thailand. In line with social exchange theory, this study indicated that employees who felt that their organizations and supervisors valued their contribution and cared about their well-being would be more likely to have lower level of turnover intention and higher level of organizational citizenship behavior. Moreover, it was found affective and normative commitment partially mediated the effect of perceived organizational and supervisor support on organizational citizenship behavior. This study enhances our understanding about the roles of organizational commitment in the Thai workplace, and provides some practical implications how to manage Thai employees.

• The monthly packaging world
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• s.272
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• pp.104-111
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• 2015

본 고는 "재활용이 가능한 고차단성 폴리올레핀 유니 소재를 활용하여 온실가스를 감축하는 친환경식품포장 개발" 프로젝트의 일환으로 "태국의 식품포장산업 조사"를 토대하여 편집한 것이며, 태국 카쎄싸국립대학교 포장재료기술학과가 태국의 식품포장산업의 현황 및 동향을 파악하여 태국의 식품포장에 주로 사용되는 유리, 플라스틱, 종이 등 주요 포장재료에 관한 정보를 얻는 데 있다. 이 자료에서는 가능한 연성 및 경성의 플라스틱포장, 종이포장, 유리포장의 생산현황을 담고 있다. 또한 포장용기의 생산량 및 추이가 태국 전역 및 주 생산 지역 전반의 차원에서 다루어지고 있으며, 포장 재료간 경쟁력도 언급한다. 제공하는 자료들은 현장조사, 설문, 인터뷰, 각종 서신, 그리고 각종 출판 자료를 바탕으로 한 것이다. 요약하면, 생산량을 기준으로 보면 주요 식품포장 재료들 중 종이, 플라스틱, 유리, 금속의 순으로 사용되었다. 종이용기 중에서는 골판지 용기가 여타 형태의 종이용기보다 많이 생산되었다. 플라스틱 포장에 있어서는 플라스틱 병과 유연성 파우치의 두 형태가 돋보였는데, 이는 대부분 음료업계에서 사용된다. 유리병도 태국의 음료업계에서 주로 사용되는데, 특히 재활용 용기로 활용된다. 지난 10년간 금속용기는 유연성 파우치와 아셉틱 카톤 팩으로 대체되어 생산량이 대폭 줄었다. 본 고에서는 한국식품연구원 박형우 책임연구원의 자료 제공을 바탕으로 태국 포장산업 실태에 대해 살펴보도록 한다.

• Environmental Engineering Research
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• v.21 no.1
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• pp.45-51
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• 2016

Membrane bioreactor (MBR) and reverse osmosis (RO) membrane system was applied to the treatment and reclamation of textile wastewater in Thailand. An experiment was carried out to determine the fouling behavior and effect of anti-scalant and biocide addition to flux decline and its recovery through chemical cleaning. The RO unit was operated for one month after which the fouled membranes were cleaned by sequential chemical cleaning method. RO flux was found rapidly declined during initial period and only slightly decreased further in long-term operation. The main foulants were organic compounds and thus sequential cleaning using alkaline solution followed by acid solution was found to be the most effective method. The provision of anti-scalant and biocide in feed-water could not prevent deposition of foulant on the membrane surface but helped improving the membrane cleaning efficiencies.

• The monthly packaging world
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• s.271
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• pp.89-103
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• 2015

본 고는 "재활용이 가능한 고차단성 폴리올레핀 유니 소재를 활용하여 온실가스를 감축하는 친환경식품포장 개발" 프로젝트의 일환으로 "태국의 식품포장산업 조사"를 토대하여 편집한 것이며, 태국 카쎄싸국립대학교 포장재료기술학과가 태국의 식품포장산업의 현황 및 동향을 파악하여 태국의 식품포장에 주로 사용되는 유리, 플라스틱, 종이 등 주요 포장재료에 관한 정보를 얻는 데 있다. 이 자료에서는 가능한 연성 및 경성의 플라스틱포장, 종이포장, 유리포장의 생산현황을 담고 있다. 또한 포장용기의 생산량 및 추이가 태국 전역 및 주 생산 지역 전반의 차원에서 다루어지고 있으며, 포장 재료간 경쟁력도 언급한다. 제공하는 자료들은 현장조사, 설문, 인터뷰, 각종 서신, 그리고 각종 출판 자료를 바탕으로 한 것이다. 요약하면, 생산량을 기준으로 보면 주요 식품포장 재료들 중 종이, 플라스틱, 유리, 금속의 순으로 사용되었다. 종이용기 중에서는 골판지 용기가 여타 형태의 종이용기보다 많이 생산되었다. 플라스틱 포장에 있어서는 플라스틱 병과 유연성 파우치의 두 형태가 돋보였는데, 이는 대부분 음료업계에서 사용된다. 유리병도 태국의 음료업계에서 주로 사용되는데, 특히 재활용 용기로 활용된다. 지난 10년간 금속용기는 유연성 파우치와 아셉틱 카톤 팩으로 대체되어 생산량이 대폭 줄었다. 본 고에서는 한국식품연구원 박형우 책임연구원의 자료 제공을 바탕으로 태국 포장산업 실태에 대해 살펴보도록 한다.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.6857-6862
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• 2015

Background: To identify the optimal cost effective strategy for the management of women having ASC-US who attended at King Chulalongkorn Memorial Hospital (KMCH). Design: An Economical Analysis based on a retrospective study. Subject: The women who were referred to the gynecological department due to screening result of ASC-US at King Chulalongkorn Memorial Hospital, a general and tertiary referral center in Bangkok Thailand, from Jan 2008 - Dec 2012. Materials and Methods: A decision tree-based was constructed to evaluate the cost effectiveness of three follow up strategies in the management of ASC-US results: repeat cytology, triage with HPV testing and immediate colposcopy. Each ASC-US woman made the decision of each strategy after receiving all details about this algorithm, advantages and disadvantages of each strategy from a doctor. The model compared the incremental costs per case of high-grade cervical intraepithelial neoplasia (CIN2+) detected as measured by incremental cost-effectiveness ratio (ICER). Results: From the provider's perspective, immediate colposcopy is the least costly strategy and also the most effective option among the three follow up strategies. Compared with HPV triage, repeat cytology triage is less costly than HPV triage, whereas the latter provides a more effective option at an incremental cost-effectiveness ratio (ICER) of 56,048 Baht per additional case of CIN 2+ detected. From the patient's perspective, the least costly and least effective is repeat cytology triage. Repeat colposcopy has an incremental cost-effectiveness (ICER) of 2,500 Baht per additional case of CIN2+ detected when compared to colposcopy. From the sensitivity analysis, immediate colposcopy triage is no longer cost effective when the cost exceeds 2,250 Baht or the cost of cytology is less than 50 Baht (1USD = 31.58 THB). Conclusions: In women with ASC-US cytology, colposcopy is more cost-effective than repeat cytology or triage with HPV testing for both provider and patient perspectives.

• The Korean Journal of Malacology
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• v.32 no.1
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• pp.55-62
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• 2016

In this study, an attempt has been made to analyze the morphology of Cephalopods distributed in Korea and collected samples from South-East Asian countries including Thailand, Indonesia, Vietnam, and China. A phylogenetic analysis was performed using the mitochondrial gene, Cytochrome c oxidase subunit I (COI) to understand the genetic divergences of the species and validate their origins. For achieving the objectives, samples were collected directly from Thailand Hat Yai, Songkhla, Indonesia Medan, Vietnam Ho Chi Minh, and Vung Tau in August 2015 and from China in September 2015. A total of 23 species of Cephalopods were identified falling under three orders, four familyies and nine genus. The species were distributed under Order: Octopoda (1 family, 3 genus, and 9 species), Order: Sepiolioda (1 family, 2 genus, and 8 species), and Order Teuthoidea (2 family, 4 genus, and 6 species). 23 species which is 1 family 3 genus 9 species in Octopoda, 1 family 2 genus 8 species in Sepiolioda, 2 family 4 genus 6 species in Teuthoidea. Phylogenetic analysis using COI gene was conducted for 18 species. For the remaining 5 species sequencing results showed severe variation and hence were not considered further. The COI phylogenetic analysis for the 18 species of Cephalopods were found consistent with the morphological identification. The excluded species will be subjected for a further detailed analysis.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.6089-6092
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• 2015

Background: The prevalence of metronidazole-resistant H. pylori is almost 50% in Thailand which severely limits the use of this drug for eradication therapy. The aims of this study were to evaluate the efficacy and safety profiles of 7-day bismuth-based quadruple therapy including metronidazole as an initial treatment for H. pylori infection in a high metronidazole resistance area. Materials and Methods: This study was performed at Thammasat University Hospital and King Chulalongkorn Memorial Hospital during January 2009 to October 2010. Patients with non-ulcer dyspepsia (NUD) with active H. pylori infection were assigned to receive seven days of quadruple therapy (pantoprazole 40 mg bid, bismuth subsalicylate 1,048 mg bid, amoxicillin 1 gm bid and metronidazole 400 mg tid). H. pylori infection was defined as positive H. pylori culture or two positive tests (rapid urease test and histology). Antibiotic susceptibility test for metronidazole by Epsilometer test (E-test) was performed in all positive cultures. At least four weeks after treatment, $^{13}C$ urea breath test ($^{13}C-UBT$) was performed to confirm H. pylori eradication. Results: A total of 114 patients were enrolled in this study, 50 males and 64 females with a mean age of 49.8 years. All 114 patients had a diagnosis of NUD. Overall eradication as confirmed by negative $^{13}C-UBT$ was achieved in 94 out of 114 patients (82.5%). 44 patients had positive cultures and success for E-test. In vitro metronidazole resistance was observed in 22/44 (50%) patients. Eradication rate in patients with metronidazole resistant strains was 16/22 (72.7%) and 20/22 (90.1%) with metronidazole sensitive strains (72.7% vs 90.1%, p-value=0.12; OR=3.75 [95%CI=0.6-31.5]). Minor adverse reactions included nausea, bitter taste, diarrhea and black stools but none of the patients dropped out from the study. Conclusions: Initial treatment with 7-day bismuth-based quadruple therapy including metronidazole, amoxycillin and pantoprazole is highly effective and well tolerated for metronidazole-sensitive H. pylori infections. However, the efficacy markedly decline with metronidazole resistance. Longer duration of this regimen might be required to improve the eradication rate and larger multi-center studies are needed to confirm this hypothesis.