• Title/Summary/Keyword: Tetsuo

Search Result 135, Processing Time 0.028 seconds

Rejection of DNA, Protein-DNA Complexes and Chromatin by Hollow Fiber Membranes

  • Higuchi, Akon;Hara, Mariko;Sato, Tetsuo;Ishikawa, Gen;Nakano, Hiroo;Satoh, Sakae
    • Proceedings of the Membrane Society of Korea Conference
    • /
    • 1996.10a
    • /
    • pp.18-21
    • /
    • 1996
  • Virus and DNA removal in bio-drug manufacturing processes has received a great deal of attention in recent years. Removing of a virus using a membrane process is a promising method, because inactivated virus can be removed from the bio-drug and the process can be used as an additional and security inactivation after the method of general heat-inactivation of the virus in the bio-drug. The FDA and the biopharmaceutical industry have recently announced strict guidelines for impurities of virus and DNA contamination. The regulatory guidelines on residual amounts of DNA in mammalian cell culture products require DNA contamination of less than 100 pg/dose. Therefore, permeation and rejection of DNA through the porous membranes have become important in the application of DNA removal in bio-drug manufacturing using membrane technology. In this study, the permeation of DNA and chromatin through regenerated cellulose hollow fibers that have a mean pore diameter of 15 nm was investigated.

  • PDF

Contribution of light in high-energy film dosimetry using water substitute phantoms

  • Fujisaki, Tatsuya;Saitoh, Hidetoshi;Hiraoka, Takeshi;Kuwabara, Akio;Abe, Shinji;Inada, Tetsuo
    • Proceedings of the Korean Society of Medical Physics Conference
    • /
    • 2002.09a
    • /
    • pp.272-274
    • /
    • 2002
  • The contribution of light in high-energy film dosimetry was examined using six commercially available solid water substitute phantoms. As six commercially available phantoms; RMI-451, Mix-DP, WE211, WE211-Black, PMMA and PMMA Black were evaluated in this study. It is difficult to evaluate the contribution of Cerenkov radiation and the optical permeability to the relative and/or absolute dosimetry using unpacked film in these phantoms. Therefore the contribution of Cerenkov radiation was estimated by the comparison between film densities in the shielded side (shutting off the light) and unshielded sides on a phantom. The effect of optical permeability was measured under ambient light by the time scale method. The results suggest that the use of black colored phantoms may improve the accuracy of dose measurement in film dosimetry.

  • PDF

A control system for dual-axis linear motor

  • Uchida, Yoshiyuki;Nohira, Shigemitsu;Seike, Yoshiyuki;Shingu, Hiroyasu;Sumi, Tetsuo;Furuhashi, Hideo;Yamada, Jun
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1992.10b
    • /
    • pp.340-343
    • /
    • 1992
  • Fundamental positioning characteristics of a dual-axis Sawyer linear motor are described. The Sawyer motor is capable of high positional accuracy. An electronic control unit of the motor whose velocity is proportional to the frequency of the electric current was produced in our laboratory. The positioning system was constructed using two Sawyer motors, an air bearings suspension unit and an electronic control unit. The stable motion of the motor was confirmed on the open loop operation. The adjustable operating conditions were the live load of 1 kg, the maximum acceleration of 1.2G and the maximum velocity of 350 mm/s. Absolute positioning accuracy was improved within .+-.5.mu.m, on microstep operating conditions of dividing one pitch of 508.mu.m into 508 steps. The following two conclusions were obtained. An accelerating-cruising-decelerating control is effective for reduction in the travel time required. Also, microstep operation is effective for improving the resolution of position.

  • PDF

Precise open-loop positioning using LPM with error correction

  • Furuhashi, Hideo;Shingu, Hiroyasu;Hayashi, Niichi;Watanabe, Shigeo;Sumi, Tetsuo;Uchida, Yoshiyuki
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1995.10a
    • /
    • pp.211-214
    • /
    • 1995
  • A precise open-loop positioning system using linear pulse motor has been developed. The system is operated in a microstepping mode by controlling the electric current. One step of 508 .mu.m (tooth pitch of the linear pulse motor) is divided into 508 micro-steps equally. The displacement is measured with a system using a Fiezeau-type interferometer. Periodical positioning error with a period of the tooth pitch was observed in this system. Therefore, the position is corrected using the error. The error is stored into computer in advance, and the microstep current is corrected on basis of the stored data. Although the positioning error of the system without the correction was .+-.4.5 .mu.m, that with the correction was decreased to .+-.1.0 .mu.m.

  • PDF

CHARACTERIZATION AND STABILIZATION OF WASTE DUSTS FROM SHREDDED AUTOMOBILES INDUSTRIES

  • Takashi, Furuyama;Abel, Bissombolo;Sukeyuki, Mori;Masamichi, Hata;Yoshitsugu, Koga;Tetsuo, Ikejiri
    • Proceedings of the IEEK Conference
    • /
    • 2001.10a
    • /
    • pp.699-704
    • /
    • 2001
  • Until recently, disposal to landfill has been the most convenient way to deal with the increasing amount of residues the shredding industries produce. But the shortage of such disposal sites and the risk that liquid drained from these waste dusts may pollute ground water have increased the environmental pressures to find more effective solutions. The present study is an alternative approach that suggests identifying waste dusts characteristics and selecting an appropriate binder for hazardous materials to reduce the amount of contaminants (mainly lead) that were leaking into the soil. Investigations on the characteristics of automobiles waste dusts show that these materials are composed mainly of cottons and sponge like substances, plastics, rubber, glasses and gravel, metals, and electric wires. Besides, the percentage in weight of organic (inflammable) materials is about 70% and the lead contamination, which has not a ionic but a particulate nature, is particularly remarkable in cottons and sponge like materials. Binding additives such as K-20 and sodium carbonate were not effective but the addition of 5 % of cement (in weight of the investigated sample) followed by a 3-minute stirring and a 4-hour storage could drastically reduce the run off of lead below the maximum authorized level. No addition of water was necessary in this method.

  • PDF

DIGITAL PROCESSING SYSTEM FOR KVN DATA AQUISITION (KVN 자료획득을 위한 디지털 처리 시스템)

  • OH SE-JIN;ROH DUK-GYOO;CHUNG HYUN-SOO;HAN SEOG-TAE;Wajima Kiyoaki;Saso Tetsuo;Kawaguchi Noriyuki;Ozeki Kensuke;CHOI HAN-GYU
    • Publications of The Korean Astronomical Society
    • /
    • v.19 no.1
    • /
    • pp.101-107
    • /
    • 2004
  • This paper describes the digital back-end system for getting the data to analyze the user observation mode by digitalize the analog data after receiving the space radio using the radio telescope, The received analog data will be digitalized by high-speed sampler with 1 Gsps for 4 channel frequency band of millimeter wave, and the digital data will be transported through the fiber-optic digital transmission system and WDM(wavelength division multiplex) to observation building, The wideband digital FIR(Finite Impulse Response) filters analyze the data for user observation mode to record the data in high-speed recorder with 1 Gbps. In this paper, we introduce the overall system configuration and features combined by various information and communication technology in radio astronomy briefly, which will be adopted by KVN(Korean VLBI Network).

Future Deep Ocean Resources and the Technologies for Commercial Development

  • Yamazaki, Tetsuo
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
    • /
    • 2006.11a
    • /
    • pp.14-20
    • /
    • 2006
  • During the 11 year period of 1995-2005, there was about a 40% increase in the world copper demand mainly because of the Asian economic growth. In the increase, about a half was consumed by China. Most of the China's copper demand increase has been taken place over the final 5-6 years of that period. The growth is expected to continue for several years, and in 10 years or sooner the same situation is expected for India. Copper is the third metal in global demand, but its little abundance in the Earth's crust is not well recognized. From the production rate and the abundance, a copper shortage, or crisis, has a high probability than the other metals. Deep ocean mineral resources such as manganese nodules in the Clarion-Clipperton Fracture Zones, Kuroko-type massive seafloor sulfides (SMS), and cobalt-rich manganese crusts in the EEZ and the high sea areas have big potentials for the future sources. We need to re-evaluate their potentials as copper resources and other metals to realize their developments. The same situation is under progress in the hydro-carbon markets. Methane hydrates that are classified into non-conventional hydro-carbon resources have an important role as the future sources, too.

  • PDF

Separation and Identification of Volatile Components of Apple Fruits after Harvest (수획후(收獲後) 사과과실(果實)의 향기성분(香氣成分)의 분리(分離) 및 동정(同定))

  • Kim, Sung-Dal;Odagiri, Satoshi;Ito, Tetsuo
    • Applied Biological Chemistry
    • /
    • v.32 no.2
    • /
    • pp.143-147
    • /
    • 1989
  • The volatile compounds of McIntosh apples were separated and identified at the stage of climacteric maximum. 21 compounds were identified from head space method and classes of that were 13 kinds of esters, 6 of alcohols, an aldehyde and a ketone. From simultaneous steam distillation-extraction method, 37 compounds were identified and classes of that were 20 kinds of esters, 14 of alcohols, 2 of aldehydes and a ketone. Esters were the most abundant flavor component in the both methods and next was alcohols.

  • PDF

Enzyme Sensors Modified with Avidin/Biotin Systembased Protein Multilayers

  • Anzai, Jun-Ichi;Du, Xiao-Yan;Hoshi, Tomonori;Suzuki, Yasuhiro;Takeshita, Hiroki;Osa, Tetsuo
    • Analytical Science and Technology
    • /
    • v.8 no.4
    • /
    • pp.591-596
    • /
    • 1995
  • Enzyme multilayers composed of avidin and biotin-labeled enzymes were prepared on the surface of electrode, through a strong affinity between avidin and biotin (binding constant: ca $10^{15} M^{-1}$). The enzyme multilayers were useful for the improvement of the performance characteristies of enzyme sensors. The output current of the enzyme sensors depended linearly on the number of enzyme layers deposited. Thus, lactate oxidase (LOx) and alcohol oxidase (AlOx) were deposited after being modified with biotin for constructing enzyme sensors sensitive to L-lactate and ethanol respectively. It was also possible to deposit two different kinds of enzymes successively in a single multilayer. The glucose oxidase (GOx) and ascorbate oxidase (AsOx) were built into a multilayer structure on a Platinum electrode. The GOx, AsOx multilayer-modified electrode was useful for the elimination of ascorbic acid interference of the glucose sensor.

  • PDF

Development of Characteristic Internship Program on Engineering Education

  • Oka, Tetsuo;Tanabe, Yuji;Abe, Kazuhisa;Narumi, Takatsune;Sato, Takashi;Tsubokawa, Norio;Kaneko, Futao
    • Journal of Engineering Education Research
    • /
    • v.17 no.4
    • /
    • pp.68-73
    • /
    • 2014
  • A practice on learn-by-doing career education programs has been operated in Faculty of Engineering in Niigata University from 2006. The purpose of the activity is reduction of early unemployment which is due to the gaps between the situations which university students would expect in their job hunting processes and those of their practical work places after getting jobs. We developed a novel internship program to let the students notice the practical situations of engineers outside the university. A major part of the program is composed of two different kinds of internships and what we call a career design workshop. The characteristic programs are called "Market Internship" and "Technology Internship". In the activities, they are organically connected with each other. In the paper we refer to one of the unique internship programs "Technology Internship", which is characterized as a longer-term practice than usual. In the course of one-month internship practices, the students obtained deeper understandings and closer relationship to the practical work places of the companies than usual internships which last less than two weeks. The students estimated these unique experiences effective for their job hunting in near future.