• Title/Summary/Keyword: Testing body

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Safety of a Traditional Korean Medicine, Cheonggan extracts (CGX): A 2-week Single-dose Toxicity Study in SD Rats and Beagle Dogs

  • Shin, Jang-Woo;Cho, Jung-Hyo;Seo, Dong-Seok;Sung, Nak-Won;Kwon, Min;Son, Chang-Gue
    • The Journal of Korean Medicine
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    • v.30 no.6
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    • pp.27-34
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    • 2009
  • Objectives: To evaluate the acute toxic effects and approximate lethal dose of Cheonggan extracts (CGX) in SD rats and beagle dogs. Methods: Male and female rats were divided into 4 groups (Control, CGX 1250, CGX 2500, CGX 5000) respectively and male and female dogs were divided into two groups respectively (Control, CGX 5000) respectively. A single oral dose of CGX was treated to the rats and dogs. Mortality, signs of gross toxicity, and behavioral changes were observed over 14 days. All animals were observed every hour for 4 hours after administration and once a day thereafter for 14 days. Body weights were determined at $0_{th}$, $7_{th}$, and $14_{th}$ days. All surviving animals were sacrificed and necrotized. Major organs were inspected visually for gross findings. Results: No animals died in any of the groups during the experimental period (2 weeks), rats or dogs. Body weights of rats and dogs during the experiment continuously increased in all groups but there was no significant change. No abnormal clinical signs were observed for 2 weeks after a single administration of CGX in any dose group of CGX, rats or dogs. No abnormal findings in major organs were observed in any group of rats or dogs. Conclusion: CGX does not have acute toxic effects in rats or dogs. Therefore, an approximate lethal dose is assumed to exceed 5000 mg/kg in both rats and dogs.

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A Study on the Injury Assessment of Helicopter's Crew with Multi Point Restraint System under Drop Impact (낙하 충격을 받는 다점 구속 장치를 착용한 헬기 승무원의 상해도 평가에 관한 연구)

  • Lee, Jung-Hyun;Lee, Young-Shin
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.33 no.6
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    • pp.590-599
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    • 2009
  • In this paper, a method of modeling seat belts on crew seat during dynamic seat testing was studied. The body segments of the occupant were modeled with joints. The joints consisted with various stiffnesses, dampings, and frictions. Three types of seat belt restraint systems were investigated. The analysis for on the injury assessment of helicopter's crew under drop impact was conducted. The effectiveness of the seat belt system for crashworthiness and safety was evaluated. As the results of impact analysis, head, neck and spine of the crew can be easily damaged in the vertical direction more than the longitudinal direction. Based on the verified model, behavior of human body was studied with three-point restraint systems. The displacement and injury level of the 12-point restraint system was the smallest.

The Effects of Feed Supplementation Method, Sex and Weight of Experimental Animal on Metabolizable Energy Value (흰쥐의 성별, 체중 및 실험사료의 첨가 방법이 대사 에너지 이용성에 미치는 영향)

  • 김은미
    • Journal of Nutrition and Health
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    • v.28 no.8
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    • pp.717-726
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    • 1995
  • This study was to investigate the validity of energy measurement system by using different body size and sex of rats and feed supplementation methods. There appeared no statistical differences in energy(AME, AMEn) utilization between male and female rats with average 200g body weight, and between male rat of 200g and 300g body weight. Glucose replacing corn in the basal diet or replacing diet itself at a level of 30% by weight appeared to have the same metabolizable energy value, suggesting that either methods to supplement test ingredient brought about the same results. Consequently, following suggestions could be made from results of present study : first, Sprague-Dawley rate of either sex weighing 200-300g may be used as an animal model to obtain in vivo metabolizable energy from dietary carbo-hydrates or sea foods. Second, the testing ingredients may be added at the expence of corn in the basal diet at 30% level.

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Testing Evaluation for Stand-Alone Cervical Cage (경추용 자립형 케이지의 실험적 평가)

  • Baek, Myong-Hyun;Lee, Mun-Hwan
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.11
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    • pp.937-941
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    • 2016
  • Stand-alone cervical cage consists of a PEEK body, Ti plate, and screw, which are configured as a single-piece. Through a single operation, this implantable medical device is capable of completely fixing the cervical vertebral body. For example, instead of a plate, which is normally used, the intervertebral disc is removed and replaced with a cervical cage. It should be noted that in Korea, KFDA guidelines for a stand-alone cervical cage have not yet been suggested. Therefore, the aim of this study is to present the systematic study of the static compression test, static torsion test, dynamic compression test, and expulsion test. Further, the test method is designed to refer to the ASTM standard and relative literature.

Hydraulic Level Control System of Combine Body (콤바인 차체의 유압 수평제어 장치에 관한 연구)

  • Lee S. S.;Mun J. H.;Park W. Y.;Lee C. H.;Lee K. S.;Hwang H.
    • Journal of Biosystems Engineering
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    • v.29 no.5 s.106
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    • pp.425-432
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    • 2004
  • In harvesting rice and barley using combine, the inclination of the body caused by the irregular surface condition of the field and the soil sinking from the unbalanced weight during the grain collection used to make harvesting operation difficult and even impossible. To overcome such a problem hydraulic system far automatic and manual leveling control of a combine has been developed. The system was composed of the combine body and the hydraulic level control system mounted on it. The maximum height of ground clearance was set up to be 290mm. And the limit angle of the leveling control was set up to be $\pm7^{\circ}$. The proposed controller and hydraulic system was implemented to the prototype combine. The prototype combine was designed and built as a separable structure with the body and the track of it. This paper shows results of a specification and design testing with the hydraulic level control system far body of combine.

Correlation between structures related to movement, activity, and participation in Disabled Persons Living at Home (재가 장애인의 운동관련 구조손상 영역 및 활동과 참여 영역의 상관관계 분석)

  • Park, Seung Kyu;Heo, Jae Won
    • The Journal of Korean Physical Therapy
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    • v.26 no.2
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    • pp.130-135
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    • 2014
  • Purpose: The purpose of this study was to examine the impairments of body structures, activity limitation, and participation restriction. In addition, we wanted to provide basic data on correlation between impairments of body structures, activity, and participation in Disabled Persons Living at Home. Methods: After selection of 128 people with physical disabilities more than the third level and brain damage disabilities living at home, we conducted testing for impairments of body structures, activity, and participation, according to the ICF checklist. Results: Impairments of body structures was highest in the upper and lower extremity. 2) Mobility, domestic life, and self care were more limited. 3) Also, the structure related to movement showed correlation with mobility, domestic life, and self care. Conclusion: We observed differences in participation and activities of persons with disabilities Living at Home depending on the impairments of body structures. After thorough review of the status of Disabled Persons Living at Home, we decided to appropriate support and social services.

A Novel Approach to Prevent Pressure Ulcer for a Medical Bed using Body Pressure Sensors

  • Young Dae Lee;Arum Park
    • International Journal of Internet, Broadcasting and Communication
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    • v.16 no.3
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    • pp.146-157
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    • 2024
  • Despite numerous air mattresses marketed to prevent Pressure Ulcers (PU), none have fully succeeded due to residual pressure surpassing critical levels. We introduces an innovative medical bed system aiming at complete PU prevention. This system employs a unique 4-bar link mechanism, moving keys up and down to manage body pressure. Each of the 17 keys integrates a sensor controller, reading pressure from 10 sensors. By regulating motor input, we maintain body pressure below critical levels. Keys are equipped with a servo drive and sensor controller, linked to the main controller via two CAN series. Using fuzzy or PI/IP controllers, we adjust keys to minimize total error, dispersing body pressure and ensuring comfort. In case of controller failure, keys alternate swiftly, preventing ulcer development. Through experimental tests under varied conditions, the fuzzy controller with tailored membership functions demonstrated swift performance. PI control showed rapid convergence, while IP control exhibited slower convergence and oscillations near zero error. Our specialized medical robot bed, incorporating 4-bar links and pressure sensors, underwent testing with three controllers-fuzzy, PI, and IP-showcasing their effectiveness in keeping body pressure below critical ulcer levels. Experimental results validate the proposed approach's efficacy, indicating potential for complete PU prevention.

Consumer characteristics of Body Mass Index groups, and the effect of body satisfaction and self-esteem on the involvement in dieting among females aged 25-49 years (25-49세 여성의 Body Mass Index 수준에 따른 소비자 특성과 신체만족도 및 자아존중감이 다이어트 관여도에 미치는 영향)

  • Jeong, Su-mok;Yoh, Eunah
    • The Research Journal of the Costume Culture
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    • v.28 no.5
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    • pp.591-606
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    • 2020
  • The aim of this study is to explore diverse characteristics of females aged 25 to 49 years grouped according to Body Mass Index(BMI), and to investigate the effect of body satisfaction and self-esteem on involvement in dieting within each BMI group. In total, 549 females who participated in an online survey were divided into groups based on BMI(underweight, normal, and overweight). Results demonstrated three key factors, as follows. First, differences were identified among BMI groups according to demographic characteristics(age, household income, and marital status), although no difference according to education level was found. Second, differences according to BMI groups were found in body satisfaction and involvement in dieting, whereas were not found in self-esteem. Third, model testing for each BMI group showed, a positive correlation between body satisfaction and self-esteem in all three groups. However, there was a difference in causal relationships among variable across BMI groups. Body satisfaction negatively affected and self-esteem positively affected involvement in dieting for the underweight and normal groups, whereas there was no causal relationship between variables in the overweight group. Based on these results, basic information of groups segmented by the level of BMI was obtained, which could be used for both academic and practical implications.

Biomechanical Analysis and Evaluation Technology Using Human Multi-Body Dynamic Model (인체 다물체 동역학 모델을 이용한 생체역학 분석 및 평가 기술)

  • Kim, Yoon-Hyuk;Shin, June-Ho;Khurelbaatar, Tsolmonbaatar
    • Journal of the Korean Society for Nondestructive Testing
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    • v.31 no.5
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    • pp.494-499
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    • 2011
  • This paper presents the biomechanical analysis and evaluation technology of musculoskeletal system by multi-body human dynamic model and 3-D motion capture data. First, medical image based geometric model and material properties of tissue were used to develop the human dynamic model and 3-D motion capture data based motion analysis techniques were develop to quantify the in-vivo joint kinematics, joint moment, joint force, and muscle force. Walking and push-up motion was investigated using the developed model. The present model and technologies would be useful to apply the biomechanical analysis and evaluation of human activities.

Research on Thermal Comfort by Increasing Air Conditioner Temperature (에어컨 온도상승에 따른 온열쾌적성 변화에 관한 연구)

  • Kim, Hyung-Chul;Kum, Jong-Soo;KIM, Dong-Gyu;CHUNG, Yong-Hyun
    • Journal of Fisheries and Marine Sciences Education
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    • v.18 no.2
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    • pp.77-84
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    • 2006
  • This research evaluates thermal comfort by comparing the case of maintain cooing temperature of room with the case of raising it at the point of time that human body begins to adapt. An experiment uses constant temperature & humidity chamber 2 places. Pretesting room make up summer season environment, the testing room control by air-conditioner. In condition that maintain temperature of $33^{\circ}C$. The subjects stay in the pretesting room during the 30 minute for the heat storage amount of the normal summertime. The subjects stay in the testing room under each case (case 1: maintaining $24^{\circ}C$, case 2: maintaining $26^{\circ}C$, case 3: up $1^{\circ}C$ after maintaining $24^{\circ}C$ during 30 minute, case 4: up $1^{\circ}C$ after maintaining $26^{\circ}C$ during 40 minute). 1. Result of comparison of case 1 and case 2 appears that thermal sensitive vote examine from slight cool to cool and thermal comfort examine slight comfort by temperature rise at human body adaptation point of time.2. Test of case 3 and case 4 appear similar value at thermal sensitive vote and thermal comfort.3. Through the case 2 and case 4, continuous thermal comfort maintain at $24^{\circ}C$, if raise $26^{\circ}C$, same thermal comfort maintain after a human body adaptation temperature rising effect bring energy saving.