• Journal of Korean Neurosurgical Society
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• 제41권1호
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• pp.50-52
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• 2007

Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland that is one of the cause of hypopituitarism. The majority of cases occur in women during the peripartum period, and it is rare in men. Testicular feminization syndrome is a genetic disorder presenting a 46XY karyotype, but a normal female phenotype. We report a case of lymphocytic hypophysitis in a 23-year-old woman with testicular feminization syndrome.

• Advances in pediatric surgery
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• 제12권1호
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• pp.47-52
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• 2006

Testicular feminization syndrome (TFS) is a genetic disorder due to androgen insensitivity of the target organs. The most common clinical presentation of complete TFS is inguinal hernia in the infant or primary amenorrhea in the adolescence. A 7-year old phenotypically female patient was seen with a complaint of a right inguinal mass. Under the diagnosis of right inguinal hernia, high ligation was performed. Six months later, the patient showed a left inguinal mass. On operation, the mass looked like a testis. The external genitalia were normal female, but a uterus and ovary were not identified. Chromosome study showed a 46, XY karyotype and the levels of serum testosterone and dihydrotestosterone were increased after HCG stimulation. The patient was diagnosed as complete TFS and underwent bilateral gonadectomy 6 months later.

• 한국동물학회지
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• 제29권1호
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• pp.61-69
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• 1986

Teter와 Boczkowski (1966)는 testicular feminization syndrome을 두 그룹으로 분류했는데, 그것들 중에서 하나는 陰毛가 없고 정상적인 陰核을 갖고 있는 경우 (A group)이며, 다른 한 그룹은 陰毛도 있고 陰核은 팽대된 경우이다 (B group). 그러나 본 연구의 대상자는 위의 두 그룹의 중간형을 나타낸다 (C group). 각 그룹의 차이점을 알기 위하여 우리들은 鼠蹊部에서 제거한 精巢의 미세구조를 관찰하였으며, 精巢培養과 血球培養을 시도하여 染色體를 분석하였다. C 그룹의 細精管은 Leydig세포나 Sertoli세포의 분포나 성숙도 그리고 基底膜의 두께 등에서 A나 B그룹과 상이한 점을 나타낸다. 陰毛나 陰核의 형태상의 차이는 위와 같은 차이점들로 인해 야기된 것이라고 생각된다.