• 제목/요약/키워드: Temporal characteristic

검색결과 249건 처리시간 0.03초

Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus

  • Cho, Kyung-Ok;Jeong, Kyoung Hoon;Cha, Jung-Ho;Kim, Seong Yun
    • The Korean Journal of Physiology and Pharmacology
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    • 제24권1호
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    • pp.81-88
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    • 2020
  • Regulator of calcineurin 1 (RCAN1) can be induced by an intracellular calcium increase and oxidative stress, which are characteristic features of temporal lobe epilepsy. Thus, we investigated the spatiotemporal expression and cellular localization of RCAN1 protein and mRNA in the mouse hippocampus after pilocarpine-induced status epilepticus (SE). Male C57BL/6 mice were given pilocarpine hydrochloride (280 mg/kg, i.p.) and allowed to develop 2 h of SE. Then the animals were given diazepam (10 mg/kg, i.p.) to stop the seizures and sacrificed at 1, 3, 7, 14, or 28 day after SE. Cresyl violet staining showed that pilocarpine-induced SE resulted in cell death in the CA1 and CA3 subfields of the hippocampus from 3 day after SE. RCAN1 immunoreactivity showed that RCAN1 was mainly expressed in neurons in the shammanipulated hippocampi. At 1 day after SE, RCAN1 expression became detected in hippocampal neuropils. However, RCAN1 signals were markedly enhanced in cells with stellate morphology at 3 and 7 day after SE, which were confirmed to be reactive astrocytes, but not microglia by double immunofluorescence. In addition, realtime reverse transcriptase-polymerase chain reaction showed a significant upregulation of RCAN1 isoform 4 (RCAN1-4) mRNA in the SE-induced hippocampi. Finally, in situ hybridization with immunohistochemistry revealed astrocytic expression of RCAN1-4 after SE. These results demonstrate astrocytic upregulation of RCAN1 and RCAN1-4 in the mouse hippocampus in the acute and subacute phases of epileptogenesis, providing foundational information for the potential role of RCAN1 in reactive astrocytes during epileptogenesis.

The Movements of Vocal Folds during Voice Onset Time of Korean Stops

  • Hong, Ki-Hwan;Kim, Hyun-Ki;Yang, Yoon-Soo;Kim, Bum-Kyu;Lee, Sang-Heon
    • 음성과학
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    • 제9권1호
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    • pp.17-26
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    • 2002
  • Voice onset time (VOT) is defined as the time interval from the oral release of a stop consonant to the onset of glottal pulsing in the following vowel. VOT is a temporal characteristic of stop consonants that reflects the complex timing of glottal articulation relative to supraglottal articulation. There have been many reports on efforts to clarify the acoustical and physiological properties that differentiate the three types of Korean stops, including acoustic, fiberscopic, aerodynamic and electromyographic studies. In the acoustic and fiberscopic studies for stop consonants, the voice onset time and glottal width during the production of stops has been known as the longest and largest in the heavily aspirated type followed by the slightly aspirated type and unaspirated types. The thyroarytenoid and posterior cricoarytenoid muscles were physiologically inter-correlated for differentiating these types of stops. However, a review of the English literature shows that the fine movement of the mucosal edges of the vocal folds during the production of stops has not been well documented. In recent. years, a new method for high-speed recording of laryngeal dynamics by use of a digital recording system allows us to observe with fine time resolution. The movements of the vocal fold edges were documented during the period of stop production using a fiberscopic system of high speed digital images. By observing the glottal width and the visual vibratory movements of the vocal folds before voice onset, the heavily aspirated stop was characterized as being more prominent and dynamic than the slightly aspirated and unaspirated stops.

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제주지역 BVOCs의 배출량 산정에 관한 연구(2): 배출량 특성 및 실태 (A Study on the Estimation of BVOCs Emission in Jeju Island (2): Emission Characteristic and Situation)

  • 이기호;김형철;허철구
    • 한국환경과학회지
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    • 제24권2호
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    • pp.207-219
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    • 2015
  • The purpose of this study is to show the geographical distribution and the temporal variation of the emission amount of biogenic volatile organic compounds(BVOCs) emanated from forests at Jeju Island. The total emission amount of BVOCs calculated by using the CORINAIR Methodology is $3612ton\;yr^{-1}$ at Jeju Island. More than half of BVOCs emissions is come from coniferous forest, and 45 per cent from broad leaved forest. The others is attributed to grassland. Of total emission of BVOCs, isoprene accounts for 28 per cent, monoterpene for 32 per cent, and other VOCs for about 40 percent, respectively. It can be shown that $3000{\sim}10000kg\;yr^{-1}$ of BVOCs is emitted at the zone with dense forest from an altitude of 500 m to the top of Mt. Halla, and less than $1500kg\;yr^{-1}$ at the zone an altitude of below 500 meters. The monoterpene emission is more than $1500kg\;yr^{-1}$ due to the existence of a colony of Abies koreana at the place with more than 1500 meters and a community of Pinus thunbergii and Cryptomeria japonica at the elevation of 500~700 m. In the case of isoprene emission, there is $1500{\sim}3000kg\;yr^{-1}$ at the zone of an elevation from 700 m to 1500 m due to dense broad leaved forest and very little of its emission at an elevation of more than 1500 meters because there is hardly broad leaved trees grown. In this study, emission of BVOCs according to the altitude above sea level is estimated under the situation of lack of the data for broad leaved tree. More detailed data and information for the distribution of broad leaved trees are needed in order to calculate more realistic BVOC emission.

기온과 강수량의 수치모델 격자자료를 이용한 기상관측지점의 월별 군집화 (Cluster analysis by month for meteorological stations using a gridded data of numerical model with temperatures and precipitation)

  • 김희경;김광섭;이재원;이영섭
    • Journal of the Korean Data and Information Science Society
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    • 제28권5호
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    • pp.1133-1144
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    • 2017
  • 기상자료를 이용한 군집분석은 기상 특성에 근거한 기상 지역의 세분화를 가능하게 하고 군집을 이루는 지형별 기상 특성의 파악을 용이하게 한다. 이때 기상관측자료를 이용한 군집분석은 관측지점의 밀도가 다르기 때문에 우리나라의 기상특성이 고르게 반영되지 못할 수 있다. 반면 수치모델 격자자료는 $5km{\times}5km$ 간격으로 조밀하고 고른 자료의 생산이 가능하므로 우리나라의 기상 특성을 고르게 반영할 수 있다. 본 연구에서는 기온과 강수량의 수치모델 격자자료를 이용하여 군집분석을 수행하고, 그 결과를 바탕으로 기상관측지점에 대한 군집을 결정하였다. 기상 특성이 월별로 상이할 수 있기 때문에 군집분석은 월별로 수행하였으며, K-Means 군집분석 방법의 단점을 보완하고자 계층적 군집분석 방법인 Ward 방법과 결합하여 적용하였다. 그 결과 우리나라 기상관측지점들에 대해 시 공간적으로 세분화된 군집화가 이루어졌다.

포스트모더니즘 현대미술과 가구디자인의 조형적 특성에 관한 연구 - 1980년대 작품의 사례를 통한 상호연관성을 중심으로 - (A Study of the Formative Features of Painting and Furniture Design in Postmodernism - Focused on the correlation with their examples in the 1980s -)

  • 최병훈;김진우
    • 한국실내디자인학회논문집
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    • 제16권2호
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    • pp.278-286
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    • 2007
  • Postmodernism, the theory and philosophy that swayed the world in the late 20th century, can be interpreted in various ways as a critical reaction against modernism as well as, in one way, the logical extension of modernism itself. Thus, an extensive understanding of the social and temporal background of the birth of postmodernism and a macroscopic and correlative approach toward the related artistic circles, especially art, were carried out before a formative discussion on the furniture design of postmodernism. Postmodemism in the field of furniture design shares the history of birth and spirit with Memphis, the progressive design group established by Ettore Sottsass in Milan, 1980. This study identifies the formative features of pestrnodernistic furniture design around those works that express the trend of postmodernism, in particular, chairs, as well as the designers who participated in the first Memphis exhibition at the Milan Furniture Fair. By identifying such features, the correlation between postmodemism and those features expressed in the works of postmodernism paintings were examined. The works of Anselm Kiefer, a German nee-expressionist who became famous through the Venice Biennale 1980, and five young Italian trans-avant garde authors were selected as the scope of this case study. The characteristics of postmodernism in modern art were analyzed in terms of themes, shape, and content and were derived as follows; Firstly, borrowed and past-oriented themes, secondly, deconstructive, atypical, plural, emotional, and intuitional shapes, and thirdly, basic, metaphorical, and abstract content, The formative characteristics of chair design in postmodemism furniture design are as follows; Firstly, deconstructive, symbolic, and abstract shapes, past-oriented, reactionary, and primitive colors and closing, as well as the characteristic of delivering commercial and metaphorical messages. The subjects and motives of art have been succeeded by the characteristics of color and closing in furniture, the shape and techniques of fine arts by the characteristics of furniture shape, and the content of art by that of furniture. They share key words and characteristics.

2D 유한요소 해석을 통한 물 분사 펌프의 동특성 분석 (Analysis of Dynamics Characteristics of Water Injection Pump through the 2D Finite Element)

  • 이종명;김용휘;김준호;최현철;최병근
    • 한국소음진동공학회논문집
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    • 제24권6호
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    • pp.462-469
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    • 2014
  • After drilling operations at the offshore plant, crude oil is producted under high pressure. After that time, oil recovery is reduced, because the pressure of the pipe inside is low during the secondary produce. At that time injection sea water at the pipe inside through water injection pump that the device increase to recovery. A variety of mathematical analysis during the detailed design analysis was not made through the dynamics characteristic at the domestic company. 2D model has reliability of analysis results for the uncomplicated model. Also element and the node the number of significantly less than in the 3D model. So, the temporal part is very effective. In addition, depending on the quality of mesh 3D is a real model and FEM model occurs error. So, user needs a lot of skill. In this paper, a 2D finite element analysis was performed through the dynamics analysis and the study model was validated.

Changes in Photosynthetic Characteristics during Grain Filling of a Functional Stay-Green Rice SNUSG1 and its $F_1$ Hybrids

  • Fu, Jin-Dong;Lee, Byun-Woo
    • Journal of Crop Science and Biotechnology
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    • 제11권1호
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    • pp.75-82
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    • 2008
  • Functional stay-green is a beneficial trait that may increase grain yield through the sustained photosynthetic competence during monocarpic senescence in cereal crops. The temporal changes of photosynthesis and related characteristics throughout the grain filling period of a stay-green japonica rice "SNU-SG1" was compared in growth chamber conditions with three high-yielding cultivars(HYVs) and their $F_1$ hybrids with SNU-SG1. SNU-SG1 exhibited a typical characteristic of functional stay-green in terms of chlorophyll degradation and photosynthetic competence during grain filling. According to the photosynthesis-light response curve measured at 10 and 35 d after heading for the flag leaf, SNU-SG1 exhibited higher initial light conversion efficiency and thus higher gross photosynthetic rate at light saturation compared to HYVs. Light saturation point was not different among genotypes, ranging from 1000 to 1500 ${\mu}mol$ photon $m^{-2}s^{-1}$. Net photosynthetic rate at light saturation($P_{max}$) of the upper four leaves in SNU-SG1 was much higher and sustained longer throughout grain-filling than HYVs and $F_1$ hybrids. The sustained high photosynthetic competence of SNU-SG1 during grain filling was ascribed to the longer maintenance of high mesophyll conductance that resulted from not only high chlorophyll content and its delayed degradation but also the slow degeneration of photosystem II(PS II) as judged by chlorophyll fluorescence($F_v/F_m$) of flag leaves. $F_1$ hybrids showed slow degeneration of photosystem II similar to the male parent SNU-SG1 while chlorophyll degradation pattern close to female parents, thus exhibiting a little higher $P_{max}$ than female parents. These results suggest that SNU-SG1 has a typical functional stay-green trait that can be utilized for increasing rice yield potential through the improved dry matter production during grain filling.

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경상분지 남동부 광상의 분포와 콘트론과의 관계 : 재검토 (Cauldron Subsidence and Ore Mineralization in the Southeastern kyongsang basin: A review)

  • Yun, Sung-Hyo;Yang, Kyoung-Hee
    • 자원환경지질
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    • 제32권3호
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    • pp.217-225
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    • 1999
  • 부산-대구지역에 화산작용의 결과로 형성되어진 구조적 함몰대인 PVD내에 적어도 9개의 칼데라함몰대가 확인되어지며, 거의 7,000km2의 지역을 차지하고 있다. 또한 PVD의 주변부 혹은 재생한 콘트론내의 환상파쇄대나 중앙부에 관입한 심성암 내에 경쟁성이 있는 광상이 배태된고 있다. 이러한 콘드롤 함몰체와 공상의 공간적 분포는 콘트롤이 이지역의 광상분포에 중요한 역할을 했음을 보여주고 있다. 또한, 화산심성암복합체의 성분이 산성일수록 콘트롤 함몰 현상이 더욱 잘 나타내고 있다. 이는 마그마의 휘발성 성분이 콘트롤 함몰과 경제성이 있는 광상을 형성시키는 하나의 요인이었음을 지시하기도 한다. 경상분지에는 칼데라와 이와 관련된 광상이 앞으로 발견된 것이며, 콘트롤 함몰이 광상 형성 중요한 역할을 담당하였음을 입증되어질 것이다.

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Temporal Characteristics of Volatile Organic Compounds in Newly-Constructed Residential Buildings: Concentration and Source

  • Shin, Seung-Ho;Jo, Wan-Kuen
    • Environmental Engineering Research
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    • 제18권3호
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    • pp.169-176
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    • 2013
  • The present study was designed to examine the concentrations, emission rates, and source characteristics of a variety of volatile organic compounds (VOCs) in 30 newly-constructed apartment buildings by measuring indoor and outdoor VOC concentrations over a 2-year period. For comparison, seven villa-type houses were also surveyed for indoor and outdoor VOC concentrations over a 3-month period. Indoor and outdoor air samples were collected on Tenax-TA adsorbent and analyzed using a gas chromatograph (GC)/mass spectrometer system or a GC/flame ionization detector system coupled to a thermal desorption system. The long-term change in indoor VOC concentrations depended on the type of VOCs. Generally, aromatic (except for naphthalene), aliphatic, and terpene compounds exhibited a gradual deceasing trend over the 2-year follow-up period. However, the indoor concentrations of the six halogenated VOCs did not significantly vary with time changes. Similar to these halogenated VOCs, the indoor naphthalene concentrations did not vary significantly with time changes over the 2-year period. Unlike the halogenated VOCs, the indoor naphthalene concentrations were much higher than the outdoor concentrations. The indoor concentrations of aliphatic and aromatic compounds were higher for the villa-type houses when compared to those of apartment buildings. In addition, four source groups (floor coverings and interior painting, household products, wood paneling and furniture, moth repellents) and three source groups (floor coverings and interior painting, household products, and moth repellents) were considered as potential VOC sources inside apartment buildings for the first- and second-year post-occupancy stages, respectively.

다시점 비디오 부호화를 위한 효과적인 초기 종료 움직임 추정 기법 (An Effective Early Termination Motion Estimation Method for Multi-view Video Coding)

  • 윤효순;김미영
    • 한국멀티미디어학회논문지
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    • 제17권3호
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    • pp.333-341
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    • 2014
  • 다시점 비디오는 하나의 3차원 장면을 여러 시점에서 다수의 카메라로 촬영한 동영상으로 다시점 비디오 부호화는 카메라의 수에 비례하여 데이터의 양이 증가하기 때문에 계산량을 줄일 수 있는 다시점 비디오 부호화 기술이 필요하다. 본 논문에서 다시점 비디오의 부호화를 위한 움직임 추정의 계산량을 줄이면서 화질을 유지하는 움직임 추정 기법을 제안한다. 제안한 움직임 추정 기법은 움직임 벡터의 분포 특성을 이용한 효과적인 초기 종료 움직임 추정 기법이다. 제안한 움직임 추정기법은 계층적 움직임 추정 기법으로 다중 사각형 탐색 패턴, 래스터 탐색 패턴, 수정된 다이아몬드 탐색 패턴 그리고 작은 다이아몬드 탐색으로 이루어져있다. 제안한 기법의 성능은 JMVC의 고속 움직임 추정 기법인 TZ 탐색 기법과 전역 탐색 기법(FS)의 성능과 비교한 경우, 영상 화질과 비트량을 비슷하지만 움직임 추정 속도를 각각 약 1.7~4.5배, 90배 향상시킨다.