• Journal of Microbiology and Biotechnology
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• v.30 no.2
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• pp.187-195
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• 2020

To understand the molecular mechanism involved in the survivability of cold-tolerant lactic acid bacteria was of great significance in food processing, since these bacteria play a key role in a variety of low-temperature fermented foods. In this study, the cold-stress response of probiotic Lactobacillus plantarum K25 isolated from Tibetan kefir grains was analyzed by iTRAQ proteomic method. By comparing differentially expressed (DE) protein profiles of the strain incubated at 10℃ and 37℃, 506 DE proteins were identified. The DE proteins involved in carbohydrate, amino acid and fatty acid biosynthesis and metabolism were significantly down-regulated, leading to a specific energy conservation survival mode. The DE proteins related to DNA repair, transcription and translation were up-regulated, implicating change of gene expression and more protein biosynthesis needed in response to cold stress. In addition, two-component system, quorum sensing and ABC (ATP-binding cassette) transporters also participated in cell cold-adaptation process. These findings provide novel insight into the cold-resistance mechanism in L. plantarum with potential application in low temperature fermented or preserved foods.

• World Technopolis Review
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• v.1 no.1
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• pp.27-41
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• 2012

The science and technology park movement has been developing for over 60 years. The first developments simply relied on the co-location of tenant companies and the park's host to encourage technology transfer. This is in contrast with their modern counter parts which offer a range of active links between tenant companies and host organisations as well as a raft of business development services to support technology commercialisation. Many of these sites have also become important centres in regional innovation plans. In these cases they are supported by a range of local, regional and national policies that are aimed at establishing a business, technology and social environment which support innovation. The paper examines both the business development programmes developed by science and technology parks to support technology commercialisation and the macro conditions that are now being developed to support innovation.

• Journal of Korean Institute of Industrial Engineers
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• v.41 no.6
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• pp.530-539
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• 2015

A business model (BM) can be developed based on a business model framework (BMF) consisting of key components such as value proposition, customers, and resources. To systematically generate and analyze emerging BMs such as healthcare BM, an integration of diverse BMF components is needed. The present study is to establish a comprehensive BMF and evaluate its applicability to healthcare BMs. Based on a review of eight BMF studies, ten BMF components were identified and classified into five major components (value proposition, resources, organizing model, customers, and revenue model) and five minor components (technology, service platform, delivery, competitive strategy, and growth/exit) by analyses of frequency and functional importance. Lastly, the BMs of three emerging healthcare companies (WellDoc, Inc., CFW Shops, and Aravind Eye Care System) were analyzed and compared in terms of the proposed BMF components. The comprehensive BMF components presented in the study can be of help for developing new BMs and analyzing the strengths and weaknesses of BMs.

• Proceedings of the Korean Vacuum Society Conference
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• 1996.02a
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• pp.180-180
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• 1996

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2006.06a
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• pp.184-184
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• 2006

• Korean Journal of Computational Design and Engineering
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• v.15 no.3
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• pp.204-211
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• 2010

Recently, business process management has become an important concept to define and execute business process. During the execution of the collaborative business processes defined by the consensus with manufacturing enterprises, a lot of variations can be occurred by various internal and external factors related to business. From this reason, manufacturing enterprises have tried to seek for a technology to define and execute the collaborative business process systematically under the dynamic situations approving process variation. This study defines the collaborative business process among manufacturing enterprises at first and proposes its execution technology under the dynamic situations. Here, the proposed execution technology includes the authority management of each process, sub-process, and activity for security, the forced execution of the incomplete process containing the undefined sub-process, the re-execution in a certain range of business process for correcting errors, and the dynamic selection of sub-process. Furthermore, this study implements a prototype system to check the validity of its application under the dynamic situations.

• Journal of Korean Institute of Industrial Engineers
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• v.31 no.2
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• pp.152-163
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• 2005

The focus of enterprise collaboration of supply chain management, has changed from integrating and exchanging business information to integrating and managing business processes between business partners. However, the collaboration is difficult due to the inherent complexity such as diverse business processes and dynamic business environments. To settle these problems, a reference model based enterprise architecture framework for the collaboration of supply chains is proposed in this paper. The supply chain collaboration framework is composed of three reference models capturing the different views of supply chain collaboration: supply process reference model, service component reference model, and technology and standard reference model. As the framework adapts the OMG's metadata architecture, the processes in the supply chain can be extended and integrated with other value chains, such as design chains, when it is necessary. Using the proposed framework, business managers can rapidly integrate and manage their business processes with their suppliers and customers.

• Current Photovoltaic Research
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• v.1 no.1
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• pp.33-37
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• 2013

LCPV modules under 5 suns consist of reflective optics and receiver modules, similar to a typical fixed concentration PV module. If they are to be used as a compound parabolic concentrator, which is filled with a dielectric material, a compact plate structure of the fixed CPV can be designed and built at a large acceptance angle. These types of flat-$plate{\mu}$-LCPV modules are suitable for building integrated photovoltaic modules, facade applications, mobile devices, and small home appliances. Therefore, in this study, the possibilities for other application devices were studied and presented by designing and fabricating LCPCs for CPV modules.

• Journal of Korean Institute of Industrial Engineers
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• v.28 no.2
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• pp.201-215
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• 2002

In this paper, we use a structural equation model to diagnose success factors on commercialization of information and communication technology considering the characteristics of commercialization process in terms of the type of technology, technology provider and technology receiver. The results of our study indicated the following. The transferor's research ability has significant effects on the commercialization by small businesses with low R&D expenditure to sales ratio, and the business management ability plays an important role in the commercialization by the relatively large (over 100 employees) companies with low R&D expenditure ratio. During the commercialization of the technology independently researched by government run institute or university, the transferee's business management ability is crucial to success. To those companies which run the existing business with high R&D expenditure ratio, their ability to utilize technology is essential. When the independently researched technology is used in the new business, the companies' business management ability and the role of technology transfer center are the important factors on the commercialization. Based on these findings, we suggest some strategies to effectively promote R&D efforts for successful commercialization.

• Elastomers and Composites
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• v.56 no.1
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• pp.32-42
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• 2021

The vulcanizate structure of silica-filled compounds is affected by the filler-rubber interaction (FRI) due to the silica-rubber coupling reaction and the chemical crosslink density (CCD) of the matrix rubber. In this study, the vulcanizate structure changes of silica-filled compounds according to the silane and sulfur variation were quantitatively analyzed using the Flory-Rehner and Kraus equations. In efficiency vulcanization (EV) conditions with low sulfur content, FRI increased when the bis-[3-(triethoxysilyl)propyl]tetrasulfide (TESPT) content increased, and the CCD clearly decreased. By contrast, in semi-EV conditions with high sulfur content, as TESPT content increased, the FRI increased the same way EV conditions, but the CCD was unchanged. Based on these results, it was confirmed that FRI of the silica-filled compounds increased as TESPT content increased, but CCD decreased or retained similar values according to the vulcanization system, indicating that the formation reaction of FRI was preferred over CCD.