• Asian Journal of Innovation and Policy
• /
• v.5 no.3
• /
• pp.293-314
• /
• 2016

Patent information as a proxy measure of technological capability has been utilized to establish technological strategies of firms. It is important to monitor what competitors' plans for direction on research and development in the initial stage of new industry. Cancer metabolism has been considered as a beacon of hope for cancer research because it is anticipated that the research field will play a central role in developing effective cancer therapies. There is little attention given to understanding the status quo of organizational configurations. By utilizing network analysis, six sub-groups of cancer metabolism were categorized and the relationship between an individual field and participants were analyzed based on cluster and entire network-level. Although the largest drug and biotech companies tried to take an initiative across the whole fields, the differences in technological capabilities between them was discovered. This paper attempts to improve the validity of the suggested procedure and is significant in that it looks at the entire structure of cancer metabolism research from a strategic perspective for the first time.

• The Journal of Industrial Distribution & Business
• /
• v.11 no.4
• /
• pp.7-18
• /
• 2020

Purpose: This research investigates the impact of technology adoption on organisation productivity. The framework has three independent variables viz. technological change, information technology (IT) infrastructure, and IT knowledge management and one dependent variable as organisational productivity. Research design, data and methodology: An explanatory research design with a quantitative research method was employed, and data was collected using a self-administered questionnaire using online as well as an offline survey. The sample consisted of 300 IT managers and senior-level executives (production as well as service team) in leading IT companies in Malaysia selected using snowball sampling. Normality and reliability assessment was performed in the first stage utilising SPSS 22, and Confirmatory Factory Analysis (CFA) was performed with maximum likelihood estimation to assess the internal consistency, convergent validity, and discriminant validity. Finally, Structural Equation Model (SEM) and path analysis are conducted using AMOS 22. Results: The research findings demonstrated that technological change and IT infrastructure positively and significantly impact the organisation's productivity while IT knowledge management has significant but negative impact on organizational productivity of IT companies in Malaysia. Conclusion: The research concludes that all three factors plays important role in deciding organizational producvity. Recommendations, implications, limitations and future research avenues are discussed.

• Journal of Power Electronics
• /
• v.17 no.1
• /
• pp.76-87
• /
• 2017

Finite-set predictive current control (FS-PCC) is advantageous for power converters due to its high dynamic performance and has received increasing interest in multilevel inverters. Among multilevel inverter topologies, the cascaded H-bridge (CHB) inverter is popular and mature in the industry. However, a main drawback of FS-PCC is its large computational burden, especially for the application of CHB inverters. In this paper, an FS-PCC method based on a deadbeat solution for three-phase zero-common-mode-voltage CHB inverters is proposed. In the proposed method, an inverse model of the load is utilized to calculate the reference voltage based on the reference current. In addition, a cost function is directly expressed in the terms of the voltage errors. An optimal control actuation is selected by minimizing the cost function. In the proposed method, only three instead of all of the control actuations are used for the calculations in one sampling period. This leads to a significant reduction in computations. The proposed method is tested on a three-phase 5-level CHB inverter. Simulation and experimental results show a very similar and comparable control performance from the proposed method compared with the traditional FS-PCC method which evaluates the cost function for all of the control actuations.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.9
• /
• pp.209-217
• /
• 2020

The purpose of this study is to investigate the development and determinants of China-ASEAN trade relations over the period of 2000-2018. Employing both the qualitative and quantitative approaches, the results show that the trade relations between China and the Association of South East Asian Nations (ASEAN) have remarkably developed and rapidly grown over times, with a significantly important concentration on the segments of high technological and medium technological products. We also find that China's economic scale is crucially impacting on the China-ASEAN trade relations under both the aggregate and sub-sector level. It is interesting to notice that there is no evidence to support accession to the World Trade Organization (WTO) and officially forming of ASEAN-China Free Trade Agreement (ACFTA) to enhance trade relation between both sides. The findings also quantitatively indicate that there is much significant potential for the expansion of mutual trade between China and some members of ASEAN such as Brunei, Laos and Malaysia, while less potential is predicted for other members of ASEAN. It is strongly suggested that China and ASEAN should find a new proactive approach and make more efforts in improving the mutual political trusts to enhance trading activities in the coming years.

• The Journal of Internal Korean Medicine
• /
• v.36 no.2
• /
• pp.85-92
• /
• 2015

Objectives: The liver fibroscan has been developed as a noninvasive and convenient method to assess hepatic fibrosis. This study aimed to review this device in terms of its technological concept and clinical application in traditional Korean medicine (TKM). Methods: The technological background, diagnostic evaluation, and clinical usefulness of fibroscan were reviewed using various literature and clinical studies. One clinical example-a patient with hepatofibrosis who had been treated with TKM-is presented. Results: The liver fibroscan was approved as a medical device for noninvasive measurement of the hepatic fibrosis level by the Korean Food and Drug Administration (KFDA). Numerous clinical studies have confirmed that its sensitivity and specificity allow it to serve as a substitute for liver biopsy, the present gold standard diagnostic method. The accuracy and reproducibility and lack of technical risks are strong points of the fibroscan; however, it has some limitations for application, especially in patients with obesity or severe hepatitis. One clinical example showed the applicability of the liver fibroscan in herbal medicine-based treatments. Conclusions: The requirement for diagnostic medical devices is an important issue in TKM; therefore, this study provides valuable information for practitioners of TKM.

• Journal of the Korea Society of Computer and Information
• /
• v.22 no.7
• /
• pp.141-152
• /
• 2017

As the importance of technology increases, so too does its use in various areas. In education, technology is often used. However, due to teachers' lack of knowledge about technology, they often remain at the level of simple utilization, without applying it to learning. Thus, there is a growing need for Technological Pedagogical Content Knowledge (TPACK), which enables teachers to have knowledge about technology and use it appropriately given the content. Although TPACK studies are underway in many subjects, they suffer from the limited functionality of the included technology. To solve this problem, in this study, the range of technology in TPACK was extended to programming, and a TPACK-P model was developed to teach this expanded TPACK to pre-service teachers. To verify the effectiveness of this model, the TPACK-P training program developed during the 15th classes was applied to 19 pre-service teachers. We used Park and Kang (2014) as a tool to measure these teachers' TPACK before and after treatment to observe any changes. The results showed that the TPACK-P education program showed statistically significant improvement in all areas except Pedagogical Content Knowledge(PCK). Compared with the ICT-based TPACK training program, which was administered to a control group, the TPACK-P training program proved to be more effective in the development of Technological Pedagogical Knowledge(TPK) and TPACK among pre-service teachers.

• BMB Reports
• /
• v.38 no.3
• /
• pp.294-299
• /
• 2005

In this report, we describe the high-yield secretory expression of the recombinant human anti-HBsAg Fab fragment from Pichia pastoris that was achieved by co-integration of the genes encoding the heavy and light chains (both under the control of alcohol oxidase promoter) into the genome of the yeast cells. The fed-batch fermentations were carried out in a 5 L scale. Both chains of the Fab were successfully expressed upon methanol induction. The absorbance ($OD_{600}$) of the broth can reach 350~500 at the end of fed-batch phase. After the induction, the expression level of the recombinant Fab (soluble) reached 420~458 mg/L. The recombinant Fab fragment was purified from the crude culture supernatant by ion exchange chromatography and the purity of the recombinant Fab fragment was over 95%. The affinity activities of the crude fermentation supernatant and the purified Fab were analyzed by indirect ELISA, which showed that the purified recombinant Fab fragment had high affinity activity with hepatitis B surface antigen.

• Journal of the Korea Safety Management & Science
• /
• v.12 no.3
• /
• pp.321-326
• /
• 2010

Government evaluate annually a performance of government's R&D(Research & Development) and decide a budget and progress. So, a performance target setting of R&D is very important at the planning, The basic performance target setting of railroad R&D is clear. However, a scientific and technological performance target setting of railroad R&D is very difficult and a reasonable level of it can not be judged. Therefore, this study will suggest a solution for a scientific and technological performance target setting of railroad R&D through regression analysis of successfully finished railroad R&D, after judging a reasonability of a scientific and technological performance through comparing railroad R&D with the other R&D.

• Journal of Distribution Science
• /
• v.21 no.1
• /
• pp.53-63
• /
• 2023

Purpose: Big Data analytics (BDA) has been recognized to improve firm performance because it can efficiently manage and process large-scale, wide variety, and complex data structures. This study examines the determinants of Big Data analytics adoption toward marketing and financial performance of global logistic companies in Thailand. The research framework is adopted from the technology-organization-environment (TOE) model, including technological factors (relative advantages), organizational factors (technological infrastructure and absorptive capability), environmental factors (industry competition and government support), Big Data analytics adoption, marketing performance, and financial performance. Research design, data, and methodology: A quantitative method is applied by distributing the survey to 450 employees at the manager's level and above. The sampling methods include judgmental, stratified random, and convenience sampling. The data were analyzed by Confirmatory Factor Analysis (CFA) and Structural Equation Model (SEM). Results: The results showed that all factors significantly influence Big Data analytics adoption, except technological infrastructure. In addition, Big Data analytics adoption significantly influences marketing and financial performance. Conversely, marketing performance has no significant influence on financial performance. Conclusions: The findings of this study can contribute to the strategic improvement of firm performance through Big Data analytics adoption in the logistics, distribution, and supply chain industries.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.13 no.1
• /
• pp.73-87
• /
• 2018

Creativity, entrepreneurship, and technological innovation orientation are key factors for technological innovation. The main driver of technological innovation in the enterprise is the executives of the firm. According to the Upper Echelons Theory of D.C. Hambrick(2007), the creativity of the managerial individual will be put into various aspects within the organization's innovation system. The organizational innovation system is positively influenced by the creativity of the executives, and is achieved by manifesting innovation orientation and technological innovation orientation with innovative performances. The purpose of this study is to investigate using Structural Equation Modeling(SEM), whether individual creativity of executives of 132 companies with research organizations among domestic semiconductor companies in Korea influences innovation performance of firms through entrepreneurship orientation and technology innovation orientation. We applied the personal creativity level measurement index, the entrepreneurial orientation measurement factor, and the technology innovation orientation measurement factor identified in the previous research literature. The results of the Structural Equation Modeling analysis show that the creativity of executives have a positive (+) relationship with the innovation performance of firms when they are only mediated by technological innovation orientation, and entrepreneurial orientation. On the other hand, the results of the SEM shows the direct effects between the creativity of executives and innovation performance are not statistically valid. As a result, the individual creativity of executives who lead the innovation of the firm, entrepreneurial orientation, and technological innovation orientation of the researcher organization are very important factors and an inseparable relationship for the successful innovation of the firms.