• Title/Summary/Keyword: Technical Effect

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Anti-Inflammatory Effect of Rosa rugosa Flower Extract in Lipopolysaccharide-Stimulated RAW264.7 Macrophages

  • Tursun, Xirali;Zhao, Yongxin;Talat, Zulfiya;Xin, Xuelei;Tursun, Adila;Abdulla, Rahima;AkberAisa, Haji
    • Biomolecules & Therapeutics
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    • v.24 no.2
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    • pp.184-190
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    • 2016
  • Rosa rugosa Thunb, a deciduous shrub of the genus Rosa, has been widely used to treat stomach aches, diarrhoea, pain, and chronic inflammatory disease in eastern Asia. In recent years, our research team has extensively studied the Rosa rugosa flower extract, and specifically undertook pharmacological experiments which have optimized the extraction process. Our methods have yielded a standard extract enriched in phenolic compounds, named PRE. Herein, we expand our efforts and evaluated the anti-inflammatory activity of PRE on lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 macrophages. PRE significantly inhibited production of nitric oxide (NO), prostaglandin $E_2(PGE_2)$, tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6, and interleukin $1{\beta}$ (IL-$1{\beta}$), as well as expression of their synthesizing enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase2 (COX-2). Furthermore, PRE inhibited activity of mitogen-activated protein kinases (MAPK) as well as nuclear factor-kappa B (NF-${\kappa}B$) signaling pathway. Our findings are the first to explain the anti-inflammatory mechanism by PRE in LPS-stimulated macrophages. Given these results, we propose that PRE has therapeutic potential in the prevention of inflammatory disorders.

Development of New Surface Design Technique for Natural Dyeing of Silk Fabric by Salt-Shrinkage Finishing (염축가공에 의한 견직물 천연염색의 새로운 표면 디자인 구현기법 개발)

  • Kim, Chaeyeon;Yoo, Dong Il;Shin, Younsook
    • Textile Coloration and Finishing
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    • v.28 no.3
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    • pp.189-194
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    • 2016
  • The objectives of this research were to study the effect of salt-shrinkage finishing of silk on shrinkage degree and dyeing property of cochineal, and to investigate the efficacy of obtained results for imparting surface design effect on silk fabric. Ultimately it was aimed to suggest a technical process for developing natural dyed silk products with diverse design. Premordanted silk fabric was treated with $Ca(NO_3)_2$ solution(gravity: 1.45) at $90^{\circ}C$ for 1 min, washed, dried for further evaluation. The shrinkage of salt-treated fabric was calculated. The effects of salt treatment on the dye uptake of cochineal and colorfastness were investigated. The degrees of shrinkage were 10% and 3% for warp and weft, respectively. The salt treatment resulted in improving dye uptake of cochineal slightly. In addition, it improved colorfastness to washing and light. On the basis of the results, a technical process composed of premordanting, salt treatment and natural dyeing was suggested and using the process, two examples of textile design were presented. It can be concluded to impart various three dimensional surface design effect on silk fabric by applying salt-shrinkage finishing with combination of natural dyeing and mordanting.

The Effect of Medical Service Quality and Hospital's Reputation on Customer Satisfaction, Repurchase Intention, and Negative Word of Mouth as to Disease Severity (질병의 중증도에 따른 의료서비스 품질과 병원의 명성이 고객만족과 재구매의도, 그리고 부정적 구전에 미치는 영향)

  • Yoo, Dong-Keun;Suh, Seung-Won
    • Korea Journal of Hospital Management
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    • v.14 no.4
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    • pp.25-51
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    • 2009
  • This model was empirically developed to test the effect of medical service quality and hospital's reputation on customer satisfaction, repurchase intention, and negative word of mouth as to disease severity. The model was tested in the context of the hospital industry. The findings are as follows. First, medical service provider's functional quality and technical service quality have significant effect on customer satisfaction. Second, hospital's reputation has positive(+) effect on customer satisfaction and significant negative effect on negative word of mouth. Third, customer satisfaction with medical service quality has significantly positive effect on customer's repurchase intention and has negative(-) effect on customer's negative word of mouth. Furthermore, customer's negative word of mouth has negative effect on their repurchase intention. Fourth, as to different disease severity, medical service quality and hospital's reputation have different effect on customer satisfaction, repurchase intention, and negative word of mouth. When patients get slightly ill, functional service quality and technical service quality have direct influence on customer satisfaction which has positive influence on repurchase intention and negative influence on negative word of mouth. Finally, negative word of mouth has negative effect on customer's repurchase intention. However, while hospital's reputation doesn't have effect on customer satisfaction, the reputation has significantly negative effect on negative word of mouth. When patients get seriously ill, only functional service quality has positive effect on customer satisfaction which influences on customer's repurchase intention and negatively influences on negative word of mouth. On the contrary, negative word of mouth doesn't influence on customer's repurchase intention as patients want to treat serious diseases in the large general hospitals even though negative word of mouth is known to them.

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Comparison of Educational Effects of Difficult Endotracheal Intubation in the 119 Rescue Service (119구급대의 어려운 기관내삽관 교육 전·후 비교)

  • Yun, Hyeong-Wan;Yu, Eun-Yeong;Yun, Young-Hyun
    • The Journal of the Korea Contents Association
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    • v.11 no.1
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    • pp.254-265
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    • 2011
  • The purpose of this study was to examine the effect of difficult endotracheal intubation education in the 119 rescue services. The subjects in this study were 60 members of the 119 rescue services that was under the umbrella of the Fire Service Headquarters of J province. A SPSS 14.0 program was utilized to find out the effect of tough tracheal intubation education on their relevant knowledge, self-confidence, academic self-efficacy and technical Performance in consideration of general characteristics. The findings of the study were as follows: 1. They showed a significant improvement in all the knowledge, self-confidence, academic self-efficacy and technical Performance after they received that education. 2. As for connections between general characteristics and knowledge before and after that education, there were significant differences in their knowledge according to gender and career of working in the hospital, and their rank and career of working in the hospital made a significant differences to their self-confidence. Their academic self-efficacy significantly differed with rank, career of working in the hospital and academic credential. There were significant gaps among them technical Performance Case 1 according to career of working in the 119 rescue services, and technical Performance Case 2 significantly varied with age and academic credential. There were significant gaps in technical Performance Case 3 according to career of working in the 119 rescue services and career of working in the hospital after that education was provided, and technical Performance Case 4 significantly varied with age and rank before and after the education was conducted. In conclusion, the kind of education programs that aim at stirring up the interest of the 119 rescue services in advanced airway and helping the members learn about tracheal intubation accurately with confidence is urgently required.

Studies on the application of high-gloss plastic pigment for paper coating (I) - Effect of the type of plastic pigment on the quality of coated paper - (종이도공용 고광택 유기안료의 적용에 관한 연구(제1보) -유기안료의 종류가 도공지 품질에 미치는 영향-)

  • 박규재;정경모;황석우;이용규
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 1999.04a
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    • pp.1-6
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    • 1999
  • A study was made to determine the effect of plastic pigment on the coating structure and printability of coated paper. Three basic plastic pigments were investigated such as solid-bead type of plastic pigment, binder type of plastic pigment and hollow type of plastic pigment. In the systems investigated, it was observed that particle shape and structure of plastic pigment had influenced on the rheology of coating color, the state of packing, and the properties of coated paper. The materials investigated were restricted to plastic pigments commonly uesd in paper coating formualtion. Inorganic pigments used in this research were kaolin clay which is platelets and calcium carbonate which is rhombic. Three kinds of plastic pigments were blended in the color made up with two inorganic pigments, respectively. The combination of pigments were carried out (1) to determined the effect of paticle structure of plastic pigment on the state of dispersion of coating color, (2) to observe the effect of temperature of calender on the property of coated paper prepared with plastic pigment. The data indicated that binder and hollow type of plastic pigment had the best results on improving the properties of coated paper such as paper gloss, opacity and air permeability ect. and solid-bead type of plastic pigment in the next place.

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An Empirical Study on the Relationship between the Key Success Factors and the Usage Effect of the e-Sports Business (e스포츠 비즈니스의 주요 성공요인과 이용효과와의 관계에 관한 실증연구)

  • Lee, Kyung-Jin;Kim, Chang-Su
    • The Journal of Information Systems
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    • v.20 no.2
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    • pp.109-134
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    • 2011
  • The purpose of this paper is to present an overview of the characteristics of the e-sports business at a crucial point in the era of information and knowledge. That is, an investigation was conducted surrounding the key success factors of e-sports as a newly growing industry, and the relationship between the key success factors and the usage effect. In order to do this, the key success factors were extracted from interviews with e-sports experts in conjunction with a survey that was conducted to gather empirical data. The key points of the statistical analysis of the survey are as follows. First, the success factors of a policy do not have a significant effect on the usage. Second, some administrative success factors of the e-sports business include the distribution of e-sports in the form of franchise chain, the establishment of policies to prevent the excellent members of e-sports from seceding, making a good impression as a high-class sport, the frequent notice of the break-even point, and educating people on how to use the e-sports machine. Third, the development and distribution of excellent e-sports software was analyzed as a technical success factor of the e-sports business. Finally, there is no doubt that results of this study can be used to facilitate the growth of the e-sports business as a new industry related to the IT industry.

Investigation on Relationship Between Pore Structure of Coating Layer and Ink Residual Behavior - Focused on the Effect of Pigments and Inks - (도공층의 공극성이 인쇄후 잉크의 잔류 거동에 미치는 영향 - 안료와 잉크의 효과 -)

  • 김병수;정현채;박종열
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.34 no.3
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    • pp.53-58
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    • 2002
  • This paper was performed to investigate the effect of pore structure on ink residual behavior. To prepare different coating structures as substrates against inks, fine, medium and coarse calcium carbonate were used in the coating color. It is well known ink properties can affect to print qualities. After printing on the coated paper, ink layer can consider as third structure addition to paper and coating layer. To compare effect of ink properties on the surface structure and print qualities, several properties of ink were also adopted as raw material. Particle size of pigment effect on gloss evaluation of coated paper increased with calendering. It was shown that ink transfer rate increased as surface of the sample was smooth. The ink contained low viscosity resin evaluated more print gloss. Finer pigment particle size, smaller pore size and higher porosity. Pore volume of coated paper was slightly decreased with printing as the coating was prepared with the finest particle size. However, it founded that ink resin could not affect on pore volume and distribution of printed paper

Printability Improvement of Hanji using Microbial Cellulose from Saprolegnia ferax (미생물 셀룰로오스를 이용한 한지의 인쇄적성 개선에 관한 연구)

  • Kang, Jin-Ha;Park, Seong-Cheol
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.40 no.3
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    • pp.23-29
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    • 2008
  • This study was performed to improve the printability of Hanji using a microbial cellulose from Saprolegnia ferax through investigating the printability of Hanji sized with the mixture of the microbial cellulose and various kinds of sizing agents. Conclusions obtained from the results of this study were as follows. The proper concentration of a microbial cellulose in sizing a printable Hanji with it was 0.5%. In general, there was no remarkable effect but some effect on the opacity and ink density. Hanji was sized with the mixture(5:5) of microbial cellulose(0.5%) and AKD(1.0%). As a result, ink spread was remarkably improved by the girth reduction of ink spot. There was remarkable effect because the mixture(5:5) of a microbial cellulose(0.5%) and CMC(1.0%) improved not only the gloss but also the density and girth of ink spot. Mixing(7:3) with corn starch(3.0%) showed the smallest girth of ink spot among applied sizing agents. Mixing(7:3) with PVA(5.0%) also showed some effect in the density and girth of ink spot.