• 제목/요약/키워드: Tear staining syndrome

검색결과 7건 처리시간 0.02초

Tear Staining Syndrome을 보이는 Poodle에 있어서 내안각의 세균총 및 눈물의 Lactoferrin 함량 (Ocular Bacteria and Concentration of Lactoferrin in Poodle Dogs with Tear Staining Syndrome)

  • 서강문;박용호;남치주
    • 한국임상수의학회지
    • /
    • 제12권1호
    • /
    • pp.829-837
    • /
    • 1995
  • This study was performed to evaluate the effects of ocular bacteria and tear lactoferrin on the Tear Staining Syndrome(TSS) in poodle dogs. Staphylococcus, Klebsiella, Micrococcus and Pseudomonas were the most Prevalent microorganisms isolated in normal eyes of poodle dogs, whereas the predominant isolates in the poodle dogs with TSS were Micrococcus, Staptococcus and Staphylococcus. There were no significant differences between the normal and tear-stained poodle dogs in the quantity of tear lactoferrin. In vitro hair staining experiment, bacteria isolated from the eyes with TSS and lactoferrin didn't stain hair. The results have shown that either ocular bacteria or tear lactoferrins were not related to the TSS.

  • PDF

Tesr staining syndrome이 있는 poodle에서 눈물생산, 비루관 개통성 및 굴곡도 (Tear formation, the patency and the angle of bend of nasolacrimal duct in poodle dogs with tear staining syndrome)

  • 서강문;남치주
    • 대한수의학회지
    • /
    • 제35권2호
    • /
    • pp.383-390
    • /
    • 1995
  • This study was performed to investigate the characteristics of tear staining syndrome in poodle dogs. Schirmer tear test, fluorescein dye test and measurement of the angle of bend between vertical and horizontal bony nasolacrimal duct were conducted in both poodles and German shepherd dogs. There were no significant differences between normal and tear-stained poodles in tear formation determined by Schimer tear test. However, there was significantly higher tear production in German shepherds than that in normal poodles(p<0.05). In the fluorescein dye test for the measurement of tear excretion, the dye was observed within $14.5{\pm}6.5$ minutes after dropping of the dye in normal poodles, but was not observed even over 30 minutes in tear-stained poodles. German shepherds had rather rapid passage time($0.4{\pm}0.3$ minutes) than poodles in the dye excretion. In the measurement of the angle of bend between vertical and horizontal bony nasolacrimal duct through dacryocystorhinography, there were no significant differences between normal tear-stained poodles with showing $85.0{\pm}6.8^{\circ}$ and $89.8{\pm}6.5^{\circ}$, respectively. However, obtuse angle of bend($106.8{\pm}4.7^{\circ}$) was shown in German shepherds. These results have ascertained that tear staining syndrome of poodle dogs was not related to tear production but to the rate of tear excretion.

  • PDF

개의 눈물착색증후군(Tear Staining Syndrome) 치료를 위한 Trimethoprim-Sulfamethoxazole (Trimethoprim-Sulfamethoxazole for the Treatment of Tear Staining Syndrome in Dogs)

  • 조연숙;김준영;정순욱
    • 한국임상수의학회지
    • /
    • 제25권2호
    • /
    • pp.115-118
    • /
    • 2008
  • 22 dogs (31 eyes) that had treated with trimethoprim-sulfamethoxazole for tear staining syndrome at Snoopy Pet Clinic from October 2000 to September 2002 were reviewed. Of the 22 dogs, 12 were female and 10 male. Their mean (${\pm}$ SD) age was 3.5 (${\pm}\;1.3$) years. The breeds of the dogs consisted of Maltese (8 dogs), Shih tzu (6 dogs), Poodle (5 dogs), Yorkshire terrier (2 dogs), and Mixed (1 dog). The dogs received 30 mg/kg trimethoprim-sulfamethoxazole perorally twice daily for two to six weeks. 26 (19 dogs) of the 31 eyes (22 dogs) recovered completely and did not show relapse at $26{\sim}30$ weeks after treatment. Any complications did not observed. Five eyes of three dogs were not cured. Two eyes (one dogs) of them had not response to medicament and three eyes (two dogs) recurrence but the clinical signs decreased. It was considered that the trimethoprim-sulfamethoxazole was effective for the treatment in dogs with tear staining syndrome.

개에서 제3안검선 냉동수술이 눈물생산량 및 조직학적 변화에 미치는 영향 (Effects of Cryosurgery of the Third Eyelid Gland on Tear Production and Histological Changes in Dogs)

  • 서강문;공인주
    • 한국임상수의학회지
    • /
    • 제17권1호
    • /
    • pp.121-128
    • /
    • 2000
  • The effects of cryosurgery on tear production and histological changes of the third eyelid were studied in dogs. Clinically normal 12 mixed breeds weighing 2∼6 kg were divided into three groups and treated as follows; 45 seconds double freeze-thaw treated group, 60 seconds double freeze-thaw treated group and 90 seconds double freeze-thaw treated group. The significant decrease of the tear production after cryosurgery was shown in all groups throughout the observed periods(p<0.05). However, there was no difference among groups. The main complications after cryosurgery were chemosis and conjunctival injection. Other complications such as eyelid edema, eyelid depigmentation and keratitis were more preominent in group III compared to those of groups I and II. On histopathological examination, chronic inflammatory changes and regeneration of the third eyelid glands were noted in group I and predominated loss of the third eyelid glands and necrosis of hyaline cartilage were observed in group III However, such changes were less appeared in group II. The results of this study suggested that double freeze-thaw cryosurgery for 60 seconds on the third eyelid glands would be the most effective method for treating tear staining syndrome.

  • PDF

Microvascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca

  • Su, Jia-Zeng;Cai, Zhi-Gang;Yu, Guang-Yan
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • 제37권
    • /
    • pp.5.1-5.4
    • /
    • 2015
  • Dry eye syndrome is a relatively common disease of the tears and ocular surfaces that results in discomfort, visual disturbance, and tear film instability with possible damage to the ocular surfaces. Microvascular submandibular gland (SMG) transfer offers a surgical alternative for a permanent autologous substitution of tears using the basal secretion of a transplanted SMG. Long-term follow-up reveals that this technique is a lasting and effective solution for patients with severe dry eye syndrome. The uncomfortable symptoms were relieved, and the frequency of use of pharmaceutical tear substitutes was reduced. Objective examination showed significant improvement in tear film and some features of ocular surface such as breakup time of tear film and corneal staining. Patients may suffer from obstruction of Wharton's duct or epiphora after surgery. Activation of secretion-related receptors could improve the early hypofunction of the denervated SMG and prevent the duct obstruction. Reduction surgery, partial SMG transplantation, uses of atropine gel or Botulinum toxin A could be the choices of treatment for epiphora.

Effect of Korean Red Ginseng supplementation on dry eye syndrome in glaucoma patients - A randomized, double-blind, placebo-controlled study

  • Bae, Hyoung Won;Kim, Ji Hyun;Kim, Sangah;Kim, Minkyo;Lee, Naeun;Hong, Samin;Seong, Gong Je;Kim, Chan Yun
    • Journal of Ginseng Research
    • /
    • 제39권1호
    • /
    • pp.7-13
    • /
    • 2015
  • Background: Many patients with glaucoma have difficulty using antiglaucoma eye drops because of dry eye symptom. In this prospective, randomized, double-blind, placebo-controlled study, we evaluated the effect of Korean Red Ginseng on dry eye syndrome in patients with glaucoma treated with antiglaucoma eye drops. Methods: Forty-nine participants were allocated to the Korean Red Ginseng (3 g/day; n = 24) or placebo (n = 25) groups for 8 weeks. Tear film stability, fluorescein corneal staining, conjunctival hyperemia, tear production, grade of meibomian gland dysfunction, and dry eye questionnaire (Ocular Surface Disease Index) were evaluated at baseline and on completion of the treatment. Results: Almost all patients displayed dry eye symptoms and signs at baseline. After the 8-week intervention, Korean Red Ginseng supplementation significantly improved the tear film stability and total Ocular Surface Disease Index score, as compared to placebo (p < 0.01). Conclusion: Korean Red Ginseng supplementation may provide an additional treatment option for dry eye and patients with glaucoma using antiglaucoma eye drops.

조절펄스광선조사가 눈물막 지질층 두께 및 안구건조증에 미치는 효과 (Effect of Intense Regulated Pulse Light on Thickness of Tear Film Lipid Layer and Dry Eye Syndrome)

  • 길태영;배지현;곽주영;현주;최진석;박규홍;정성근
    • 대한안과학회지
    • /
    • 제59권12호
    • /
    • pp.1103-1107
    • /
    • 2018
  • 목적: 건성안 환자에서 조절펄스광선조사가 미치는 임상 효과 및 눈물막지질층 두께 변화에 대하여 알아보고자 하였다. 대상과 방법: 건성안에 대한 주관적인 불편감을 호소하는 환자 중 마이봄샘기능부전 소견을 보이며, 눈물막파괴시간이 10초 이하인 25명을 대상으로 후향적 연구를 시행하였다. 모든 대상자에 대한 조절펄스광선조사는 시술 당일, 15일, 45일 총 3회에 걸쳐 시행되었으며, 시술 전후 눈물막파괴시간, 쉬르머검사, 안구표면염색점수, 안구표면질환지수(Ocular Surface Disease Index, OSDI) 및 눈물막 지질층의 두께를 측정하여 비교 분석하였다. 결과: 조절펄스광선조사 시술 후 눈물막파괴시간은 $3.7{\pm}1.2$초에서 $4.4{\pm}2.1$초로 증가되어 통계적으로 유의한 차이를 보였으며(p=0.03), 쉬르머 검사 및 안구표면염색 점수 결과는 통계적으로 유의한 차이를 보였다(p<0.01, p=0.01). OSDI는 $39.5{\pm}17.5$점에서 $30.4{\pm}18.7$점으로 통계적으로 유의한 향상을 보였다(p=0.01). 눈물막지질층 두께는 통계적으로 유의한 변화를 보이지 않았다(p=0.49). 결론: 조절펄스광선조사 시술은 눈물막파괴시간, 쉬르머검사, 안구표면염색점수 및 주관적인 건성안 증상을 개선시키는 효과적인 치료 방법이라 생각된다.