• 제목/요약/키워드: TcB

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귀전우(鬼箭羽)(Euonymus alatus(Thunb.) Sieb)가 간암세포(肝癌細胞)(Hep3B)와 자궁암세포(子宮癌細胞)(HeLa)의 성장억제(成長抑制)에 미치는 영향(影響)에 관한 연구(硏究) (Effect of Growth Inhibition in Hep3B cell and HeLa cell by treatment of Euonymus alatus(Thunb.) Sieb extracts)

  • 최달영
    • 동국한의학연구소논문집
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    • 제7권2호
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    • pp.155-162
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    • 1999
  • 귀전우(Euonymus alatus Sieb.)가 간암, 식도암, 위암, 자궁암등의 각종 암을 치료하는 방법으로 민방에서 많이 사용하고 있다. 실제 Euonymus alatus(Thumb.) Sieb의 추출물중 Eupolyphaga simensis(ES)는 HDL-C/TC ratio와 LCATactivity를 증진시킨다. Human hepatoblastoma 세포인 Hep3B 세포의 성장억제를 유도하는 factor로는 TGF-${\beta}$, Insulin 등으로 알려져 있다. 따라서 귀전우는 간에 있어 당 대사에 관여하는 plasma HDL3-C level은 낮게 유지함으로써 간에서 지방간 이행을 억제 하여 간에서의 암 발생을 억제하는 효과를 보인다. 실험에서 귀전우가 자궁암세포보다도 간암세포에 보다 높은 세포독성을 보임으로써 여러종류의 암에 모두 적용하기는 어렵다고 보여진다. 또한 귀전우가 바이러스에 의해 유도되는 간암과 hepatocellular Carcinoma 세포에서 효과가 있는지와 HCC에서 세포의 증식억제효과를 어떤 경로를 통해 이루어지는지 계속적으로 연구가 수행되어져야 될 것이다.

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곡류 급원에 따른 흰쥐의 간과 혈중 지질농도에 관한 연구 (Effect of Cereals on Lipid Concentration of Liver and Serum the Rats)

  • 정경아;장유경
    • Journal of Nutrition and Health
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    • 제28권1호
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    • pp.5-14
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    • 1995
  • The present study was performed to investigate the effect of cereal fiber on lipid concentration of liver and serum in rats. Male Sprague-Dawley rats weighing 180$\pm$4g were divided into five groups by completely randomized block design : R, BR, B, W, and F. Each group fed a diet containing 0.7% cholesterol and a kind of cereal among rice(R), brown rice(BR), barley(B), whole wheat(W), and wheat flour(F) for 5 weeks. The results were summarized as follow : 1) Food intake. weight gain and feed efficiency ratio were not significantly different among the groups. 2) Fecal wet weight and dry weight were significantly higher in W group which fed the most amount of IDF(insoluble dietary fiber). 3) The weight of large intestine was significantly heavier in the W group compared to the others. But the weights of liver, stomach and small intestine were not significantly different among the groups. 4) Total lipid. triglyceride(TG) and total cholesterol(TC) content in liver were significantly different among the groups. The values were the lowest in the B group whose intake of SDF(soluble dietary fiber) was the highest 5) TC content in serum was not significantly different among the groups. TG content in serum was significantly lower in the rest groups than in the R group. HDL-c and free-c content in serum were significantly higher in the B group than in the rest groups. HDL-c/LDL-c, free-c/ester-c ratio were the highest in the B group but not significant. Above results show that the dietary fiber contained in cereals has physiological effects and they are different depending on fractions, IDF and SDF.

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BRATTELI DIAGRAM ISOMORPHIC TO CHACON HOMEOMORPHISM

  • Park, Seung-Seol
    • 대한수학회보
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    • 제37권3호
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    • pp.519-536
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    • 2000
  • We construct a stationary, properly ordered Bratteli diagram B=(V,E,$\geq$) so that its Vershik map is isomorphic to Chacon's homeomorphism. It is the simplest stationary, properly ordered Bratteli diagram isomorphic to (Xc, Tc). We also find a primitive and proper substitution of Chacon's transformation.

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회전하는 정사각 단면 U자형 곡관 내부의 유동 발달에 관한 수치적 연구(II) -난류 유동- (A Numerical Study on the Flow Development around a Rotating Square-Sectioned U-Bend(II) - Turbulent Flow -)

  • 이공희;백제현
    • 대한기계학회논문집B
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    • 제26권6호
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    • pp.850-858
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    • 2002
  • The present study investigates in detail the combined effects of the Coriolis force and centrifugal force on the development of turbulent flows in a square-sectioned U-bend rotating about an axis parallel to the center of bend curvature. When a viscous fluid flows through a curved region of U-bend, two types of secondary flow occur. One is caused by the Coriolis force due to the rotation of U-bend and the other by the centrifugal force due to the curvature of U-bend. For positive rotation, where the rotation is in the same direction as that of the main flow, both the Coriolis force and the centrifugal force act radially outwards. Therefore, the flow structure is qualitatively similar to that observed in a stationary curved duct. On the other hand, under negative rotation, where these two forces act in opposite direction, more complex flow fields can be observed depending on the relative magnitudes of the forces. Under the condition that the value of Rossby number and curvature ratio is large, the flow field in a rotating U-bend can be represented by two dimensionless parameters : $K_{TC}$ =Re $\sfrac{1}{4}$√λand a body force ratio F=λ/Ro. Here, $K_{TC}$ has the same dynamical meaning as $K_{TC}$ =Re√λ for laminar flow.

의사결정론을 통한 EMP 방호대책 및 수준 판단방안 제시에 관한 연구 (A Study on the Method for Judging the EMP Protection Plan and Required Level through Decision Making)

  • 김국주;박상우;백장운;박영준
    • 한국건축시공학회지
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    • 제19권2호
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    • pp.193-200
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    • 2019
  • 한반도 안보상황에서 주변국들에 의한 EMP 위협이 고조되는 상황에서 EMP 방호시설은 군의 작전수행능력을 보장할 수 있는 매우 중요한 수단이다. 이러한 EMP 방호시설은 작전을 수행하는 부대의 다양한 요소들을 종합적 고려하여 구축하여야 한다. 하지만 현 군 관의 EMP 방호기준은 80dB의 일률적인 차폐효율만을 요구하고 있다. 본 연구에서는 전문가 집단의 의견을 통해 객관적이고 통계적 방법을 사용하여 방호요구수준의 고려사항을 재선정하고자 한다. 연구방법은 델파이기법을 사용하였으며, 53명의 EMP방호 설계기준과 관련 있는 전문가들을 선정하였다. 1차 설문은 EMP 방호의 적정수준에 대하여 조사하였고, 2차 설문은 방호대책 수립시 고려요소에 대하여 분석하였다. 채택된 전문가의 의견에 대해 요인분석을 실시한 결과, EMP 방호요구수준 설정시 METT+TC 요소를 고려하여야 한다는 것을 확인하였다.

Graves병 안구증에서 $^{99m}Tc-DTPA$ 뇌신티그라피를 이용한 안구/뇌 방사능비에 관한 연구 (The Eye/Brain Radioactivity Ratio for Assessment of Graves' Ophthalmopathy)

  • 이범우;성상규;박원;서관식;최덕주;김종순
    • 대한핵의학회지
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    • 제22권1호
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    • pp.27-31
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    • 1988
  • In Graves' disease, changes in orbital tissue and structure are casued by inflammatory infiltation, which induces increase of capillary permeability and breakdown of blood-tissue barriers. Using the uptake of $^{99m}Tc-DTPA$ in inflammatory lesion, Eye/Brain radioactivity ratios in brain scintigraphy were evaluated in 15 normal controls and 40 Graves' patients. The results were as follows; 1) Eye/Brain radioactivity ratio was significantly higher in Graves' ophthalmopthy group than in control group (p < 0.005). 2) In Graves' ophthalmopathy, Eye/Brain radioactivity ratio was significantly higher in active (progressive) group than in inactive (non-progressive) group (p < 0.05). 3) There was no correlation between class of ATA classification of Graves' ophthalmopathy and Eye/Brain radioactivity ratio. 4) There was no correlation between Eye/Brain radioactivity ratio and serum activity of TBII. In conclusion, Eye/Brain radioactivity ratio using $^{99m}Tc-DTPA$ brain scintigraphy may be useful to determine the activity of Graves' ophthalmopathy and whether treatment of Graves' ophthalmopathy is necessary or not.

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국부용융성장법으로 제조한 (Sm/Y)-Ba-Cu-0계 고온복합초전도체의 CeO2첨가에 따른 초전도특성 (Superconducting Properties of (Sm/Y)-Ba-Cu-0 High Tc Composite Superconductors with CeO2 Additive by Zone-Melt Textured Growth)

  • 김소정
    • 한국전기전자재료학회논문지
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    • 제15권3호
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    • pp.269-274
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    • 2002
  • (Sm/Y)-Ba-Cu-O system high Tc composite superconductors with/without $CeO_2$ additive were directionally grown by zone-melting process, haying large temperature gradient, In air atmosphere. Cylindrical green rods of $({Sm/y})_{1.8}Ba_{2.4}Cu_{3.4}O_x$ [(Sm/Y)1.8] composite oxides by cold isostatic pressing(CIP) method using rubber mold were fabricated. The microstructure and superconducting properties were investigated by XRD, SEM, TEM and SQUID magnetometer. The size of nonsuperconducting $({Sm/y})_2BaCuO_5$ inclusions of the melt-textured (Sm/Y)1.8 sample with CeO$_2$ additive were remarkably reduced and uniformly distributed within the superconducting (Sm/Y)1.8 matrix. Both samples, with/without $CeO_2$ additive, showed an onset Tc $\geq$ 90 K and sharp superconducting transition. The critical current density Jc value of the $CeO_2$ addictive were $1{\times}10^5A/\textrm{cm}^2$ in 77 K, 0 Tesla.