• Biomolecules & Therapeutics
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• 제21권3호
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• pp.229-233
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• 2013

This study was aimed at investigating the possible effects of phytoceramide (Pcer) on learning and memory and their underlying mechanisms. Phytoceramide was orally administered to ICR mice for 7 days. Memory performances were assessed using the passive avoidance test and Y-maze task. The expressions of phosphorylated cAMP response element binding protein (pCREB), brain-derived neurotrophic factor (BDNF) were measured with immunoblot. The incorporation of 5-bromo-2-deoxyuridine (BrdU) in hippocampal regions was investigated by using immunohistochemical methods. Treatment of Pcer enhanced cognitive performances in the passive avoidance test and Y-maze task. Immunoblotting studies revealed that the phosphorylated CREB and BDNF were significantly increased on hippocampus in the Pcer-treated mice. Immunohistochemical studies showed that the number of immunopositive cells to BrdU was significantly increased in the hippocampal dentate gyrus regions after Pcer-treatment for 7 days. These results suggest that Pcer contribute to enhancing memory and BDNF expression and it could be secondary to the elevation of neurogenesis.

• Journal of Hospice and Palliative Care
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• 제20권4호
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• pp.242-252
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• 2017

목적: 본 연구의 목적은 델파이 합의방식을 통해 '완화의료 도우미'라는 새로운 직종의 직무범위를 개발하는 것이다. 방법: 호스피스 완화의료 실무와 정책에 관여하는 전문가 패널 36명이 참여하였고, 4단계에 걸친 델파이 조사를 통해 각 책무-과업-과업요소의 내용 타당도를 검증하였다. 내용 타당도는 5점 척도에서 4점 이상인 항목을 채택하였다. 결과: 4단계의 델파이 조사결과를 분석하여, 완화의료 도우미의 직무로 책무 4개, 과업 15개, 과업요소 46개를 최종 확정하였다. 결론: 본 연구를 통해 완화의료 도우미의 직무범위가 명시되었으며, 이를 통해 역할갈등과 혼란을 예방하고 서비스의 질 향상에 기여할 것으로 기대한다.

• 한국운동역학회지
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• 제30권2호
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• pp.131-144
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• 2020

Objective: The purpose of this study was to examine the effect of degrees of freedom on the multi-synergies in two hierarchies of human hand system during force production and releasing tasks. Method: In this study, the constrained movements of the aiming and releasing actions using both hands and fingers during archery-like shooting were implemented as experimental tasks. The participants produced a pulling force holding the customized frame (mimicking an archery bow, with a set of force transducers) and kept it consistently for about 5 seconds, and released fingers as quickly as possible in a self-paced manner within the next 5 seconds. An analytical method based on the uncontrolled manifold hypothesis was used to quantify the stability index (synergy index) in two hierarchies including two hands (upper hierarchy) and individual fingers (lower hierarchy). Results: The results confirmed that the positive synergy pattern showed simultaneously at the upper and lower hierarchies, and the kinetic degrees of freedom were associated with the increment of hierarchical synergy indices and the performance indices. Also, the synergy indices of both hierarchies showed significant positive correlations with the performance accuracy during the task. Conclusion: The results of this study suggest that the human control system actively uses extra degrees of freedom to stabilize task performance variables. Further increasing the degree of freedom at one level of hierarchy induces positive interactions across hierarchical control levels, which in turn positively affects the accuracy and precision of task performance.

• 한국어교육
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• 제28권4호
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• pp.63-86
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• 2017

This research aims to evaluate the effects and the shortcomings of strategies for teaching paraphrasing to foreign university students. For this study, the effects of teaching paraphrasing skills on student's academic writing was investigated through the assessment of pre- and post-test writing tasks and through a focus group interview. The teaching of paraphrasing was divided into 3 instructional sessions and the focus group interview was conducted at the end of the last session. After each instructional session three trained assessors evaluated the outcomes of pre and post task writings; the in-depth focus group interviews were conducted on seven of the students in order to define better positive effects as well as shortcomings. By comparing the scores of pre- and post-task assignments it is possible to affirm that there is a meaningful difference for overall scores; moreover, in an analysis conducted on each single sub-element of the paraphrasing skill, it emerged that except for "task completion", all other four elements of "structure", "understanding core content", "change of expression" and "academic expressions" showed a statistically significant improvement in performance. On the other hand, as a result of the focus group interview, it was possible to individuate as main shortcomings insufficient vocabulary knowledge, poor overall comprehension of the reference material, lack of practice and difficulty in connect sentences organically. It is possible to consider these elements as limiting factors in understanding the reference material and making correct citations by the students. Therefore, we suggest as supplementary instructional strategies a deeper attention to the difficulty level of the text, the introduction of devices to understand better the content of the reference material and an integrated practice of the paraphrasing skill.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제10권12호
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• pp.595-602
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• 2021

로봇은 주변 상황을 인지하고 Task를 부여받는 software oriented 형상으로 발전하고 있다. Cloud Robotics Platform은 로봇에 Service Oriented Architecture 형상을 지원하기 위한 방법으로, 상황에 따라 필요한 Task와 Motion Controller를 클라우드 기반으로 제공할 수 있는 방안이다. 휴머노이드 로봇으로 진화할수록 로봇은 로봇 3대 원칙에 따라 보편화된 일상생활 속에서 인간에게 도움을 주기 위해 사용될 것이다. 따라서 특정 개인만을 위한 로봇 이외에도, 상황에 따라 모든 인간에게 도움을 줄 수 있는 공공재로써의 로봇이 보편화될 것이다. 따라서, 생성하는 정보는 사람, 로봇, 로봇에 지능을 부여하는 클라우드 상의 서비스 애플리케이션, 로봇과 클라우드를 이어주는 클라우드 브릿지로 구성될 것으로 분석되는 Cloud Robotics Computing 환경에서 정보보안의 중요성은 인간의 생명 및 안전을 위해 필수불가결한 요소로 자리잡게 될 것이다. 본 논문에서는 지능화된 로봇을 위한 Cloud Robotics Computing 환경에서 사람, 로봇, 클라우드 브릿지, 클라우드 시스템간 통신 시 보안을 제공하여 해킹으로부터 안전하고 개인의 정보가 보호되는 로봇 서비스가 가능할 수 있는 Security Scheme을 제안한다.

• 터널과지하공간
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• 제33권3호
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• pp.189-207
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• 2023

In the present study, the thermoshearing experiment on a rough rock fracture were modeled using a three-dimensional grain-based distinct element model (GBDEM). The experiment was conducted by the Korea Institute of Construction Technology to investigate the progressive shear failure of fracture under the influence of thermal stress in a critical stress state. The numerical model employs an assembly of multiple polyhedral grains and their interfaces to represent the rock sample, and calculates the coupled thermo-mechanical behavior of the grains (blocks) and the interfaces (contacts) using 3DEC, a DEM code. The primary focus was on simulating the temperature evolution, generation of thermal stress, and shear and normal displacements of the fracture. Two fracture models, namely the mated fracture model and the unmated fracture model, were constructed based on the degree of surface matedness, and their respective behaviors were compared and analyzed. By leveraging the advantage of the DEM, the contact area between the fracture surfaces was continuously monitored during the simulation, enabling an examination of its influence on shear behavior. The numerical results demonstrated distinct differences depending on the degree of the surface matedness at the initial stage. In the mated fracture model, where the surfaces were in almost full contact, the characteristic stages of peak stress and residual stress commonly observed in shear behavior of natural rock joints were reasonably replicated, despite exhibiting discrepancies with the experimental results. The analysis of contact area variation over time confirmed that our numerical model effectively simulated the abrupt normal dilation and shear slip, stress softening phenomenon, and transition to the residual state that occur during the peak stress stage. The unmated fracture model, which closely resembled the experimental specimen, showed qualitative agreement with the experimental observations, including heat transfer characteristics, the progressive shear failure process induced by heating, and the increase in thermal stress. However, there were some mismatches between the numerical and experimental results regarding the onset of fracture slip and the magnitudes of fracture stress and displacement. This research was conducted as part of DECOVALEX-2023 Task G, and we expect the numerical model to be enhanced through continued collaboration with other research teams and validated in further studies.

• 대한수학교육학회지:수학교육학연구
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• 제27권3호
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• pp.511-536
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• 2017

수학교실에서 효과적인 논의기반 수업을 구현하기 위하여 교사는 여러 가지 교수학적 행동을 취할 수 있지만, 그 기반은 학생들의 수학 학습에 대한 이해이다. 교사는 수업 중 유발될 수 있는 학생들의 다양한 문제 해결 접근 방법에 대비하여 수학 과제에 대한 학생들의 반응 및 교수학적 대처를 사전에 예상해보는 것이 필요하다. 본 연구에서는 교사들의 수학적 담화 조정 능력 신장의 일환으로 Spangler & Hallman(2014)의 과제 대화록 작성하기 활동을 보완하여 중등수학 예비교사들의 교과교육 수업에 적용하였고, 이 과정에서 관찰할 수 있는 예비교사들의 예상하기 특징을 학생 반응과 교수학적 대처 두 가지 측면에서 조사하였다. 그 결과, 첫째, 예비교사들은 수학 과제에 대한 학생들의 반응과 그에 대한 교수학적 대처를 예상할 때에, 그 과제와 유사한 혹은 동일한 수학과제를 가르쳐 본 과거 경험에 의존하는 경향을 보였다. 둘째, 연구에 참여한 대부분의 예비교사들은 한 가지 이상의 옳은 문제해결 방법을 예상하는 것에 어려움을 느꼈고, 문제를 옳게 해결한 학생들에 대하여 그들의 문제해결법을 묻는 것 외의 수학적 사고를 탐색하거나 확산할 수 있는 발문을 하는 것에 어려워했다. 셋째, 예비교사들은 학습자의 이해 수준에 맞추어 수업을 이끌어 나가는 것의 중요성을 인식하고 있으면서도, 학생들의 다양한 반응에 대한 교수학적 대처를 예상할 때 문제해결의 결정적 힌트를 제공하거나 절차적 지식에 치중한 발문을 하여 결과적으로 처음에 제시한 수학 과제의 인지적 노력 수준을 저하시켰다. 결론에서는 본 연구의 결과를 바탕으로, 과제대화록 활동이 중등수학 예비교사들의 예상하기 능력 신장에 미칠 수 있는 긍정적인 영향과 예비교사 교육에 주는 시사점에 대하여 논의하였다.

• 한국해양공학회지
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• 제29권1호
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• pp.45-55
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• 2015

Because of the high stress concentration near the toe of a welded joint, the calculation of local stress using the finite element method which is relevant to the fatigue strength of the weld toe crack, is a challenging task. This is mainly caused by the sensitivity of finite element analysis, which usually occurs near the area of a dramatically changing stress field. This paper presents a novel numerical method through which a less mesh-sensitive local stress calculation can be achieved based on the 3D solid finite element, strictly sticking to the original definition of hot spot stress. In order to achieve the goal, a traction stress, defined at 0.5t and 1.5t away from the weld toe, was calculated using either a force-equivalent or work-equivalent approach, both of which are based on the internal nodal forces on the imaginary cut planes. In the force-equivalent approach, the traction stress on the imaginary cut plane was calculated using the simple force and moment equilibrium, whereas the equivalence of the work done by both the nodal forces and linearized traction stress was employed in the work-equivalent approach. In order to confirm the validity of the proposed method, five typical welded joints widely used in ships and offshore structures were analyzed using five different solid element types and four different mesh sizes. Finally, the performance of the proposed method was compared with that of the traditionally used surface stress extrapolation method. It turned out that the sensitivity of the hot spot stress for the analyzed typical welded joints obtained from the proposed method outperformed the traditional extrapolation method by far.

• Journal of Advanced Research in Ocean Engineering
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• 제1권2호
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• pp.106-114
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• 2015

In the fabrication of offshore oil and gas facilities, the significance of dimension control is growing continuously. But, it is difficult to determine the deformation of the structure during fabrication by simple lab tests due to the large size and the complicated shape. Strain-boundary method (a kind of shrinkage method) based on the shell element was proposed to predict the welding distortion of a structure effectively. Modeling of weld geometry in shell element is still a difficult task. In this paper, a concept of imaginary temperature pair is introduced to handle the effect of geometric factors such as groove shape, plate thickness and pass number, etc. Single pass imaginary temperature pair formula is derived from the relation between the groove area and the FE mesh size. By considering the contribution of each weld layer to the whole weldment, multi-pass imaginary temperature is also derived. Since the temperature difference represents the distortion increment, cumulative distortion curve can be drawn by integrating the temperature difference. This curve will be a useful solution when engineers meet some problems occurred in the shipyard. A typical example is shown about utilization of this curve. Several verifications are conducted to examine the validity of the proposed methodology. The applicability of the model is also demonstrated by applying it to the fabrication process of the heavy ship block. It is expected that the imaginary temperature model can effectively solve the modeling problem in shell element. It is also expected that the cumulative distortion curve derived from the imaginary temperature can offer useful qualitative information about angular distortion without FE analysis.

• 한국항해항만학회지
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• 제43권6호
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• pp.395-402
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• 2019

최근 보다 안전하고 효율적인 해상운송시스템을 위한 해결책으로 자율운항선박의 개발 및 운용에 대한 논의가 활발히 진행되고 있다. 자율운항기술은 해양사고 방지, 선박의 연비 증진, 비용 절감 등 긍정적인 측면과 함께 선원의 일자리 감소, 업무의 변화, 보안문제 등 부정적인 측면도 상존하고 있다. 향후 자율운항선박의 시대가 도래 하더라도 육상 센터에서의 제어가 이루어지게 되므로, 육상 운항사의 상황인식과 같이 새로운 인적요인 이슈가 존재할 것으로 예측된다. 본 논문에서는 자율운항선박의 개발 및 운용과정에 고려해야 할 주요 인적요인 이슈를 고찰하고, 육상 센터의 제어에 따라 예상되는 육상 운항사의 의사결정 및 업무수행에 영향을 미치는 요소에 대한 식별과 영향 요소의 평가를 위한 인적 신뢰성 분석 방안을 제시하였다.