• 인지과학
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• 제26권3호
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• pp.357-375
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• 2015

일상생활에서의 시각탐색의 대상이 되는 표적 사물의 출현 가능성 즉 출현 확률은 매우 낮은 경우부터 높은 경우까지 다양하다. 그럼에도 불구하고, 실험실 상황의 시각 탐색 연구에서 표적의 출현 확률은 대개 50%의 확률로 고정되는 경우가 대부분이다. 본 연구에서는 서로 다른 표적 출현확률의 영향 하에 시각탐색 과정에서의 정보처리 특성을 조사하였다. 지각적으로 단순한 도형자극으로 구성된 시각탐색과제가 실시되었으며, 탐색 표적이 제시되는 빈도를 저빈도(20%)와 중립빈도(50%), 또는 고빈도(80%)로 달리함으로써 표적 출현확률이 탐색 정보처리 책략에 미치는 영향을 탐색 정확도, 신호탐지 측정치 그리고 반응시간 차원에서 조사하였다. 실험 결과, 표적이 드물게 출현할수록 실수율이 증가하고 헛경보율이 감소했으며 반대로 고빈도 표적탐색에서는 역전된 패턴이 관찰되었다. 신호탐지 분석 결과, 이러한 결과는 민감도가 아닌 탐색 반응기준의 이동에 의한 것으로 확인되었다. 또한 반응시간 차원에서, 표적 있음 시행에서의 적중 반응은 출현확률과 관계없이 일정했던 반면 표적 없음 시행에 대한 정확한 기각 반응은 출현확률에 비례해 지연된 것이 관찰되었다. 이러한 결과는 표적이 빈번하게 출현할수록 표적 없음 상황에서 탐색을 종료하기 위한 탐색 역치 기준이 보수적이었음을 의미한다. 본 연구의 결과는 표적 출현확률 효과가 단순히 반응편향에 따른 속도-정확도 교환이 아닌 의사결정 기준의 변화에 기초한 상이한 탐색 정보처리 과정의 산물임을 시사한다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 추계 학술발표회
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• pp.508-518
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• 2008

Reliability and sensitivity analysis of the design parameters for a section of caisson type quaywall which is the most applicable in Korea were performed. It was tried to estimate probabilities of failure for the system of the multiple failure modes and to analyze LCC in the quaywall structure. The reliability analysis was performed by FORM. Also, sensitivity indices were estimated using the reliability indices, which may be used inferring effects of each design parameter on the reliability indices. As a result, the coefficient of friction between caisson and rubble, the moment by self weight and the moment of resistance mostly affected on the reliability indices in the sliding, overturning and foundation failure, respectively. System reliability theorem was applied in order to estimate the probabilities of failure for the system of the multiple failure modes. As the results of estimation of the probabilities of failure for the system, all cases were more conservative than those for the elements, according to both failure mode and load combination applied to series system. It entirely exceeded the target reliability index, but it was consistent with the theorem. According to the optimum LCC with the width of the caisson, the probability of failure exceeded the target probability of failure at then time. Therefore, it was judged to be insufficient to the practical application.

• 대한의생명과학회지
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• 제14권2호
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• pp.115-118
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• 2008

Salmonella typhi is frequent causes of foodborne illness and its detection is important for monitoring disease progression. In this study, by using general PCR and novel LAMP (Loop Mediated Isothermal Amplification) assay, we evaluated the usefulness of LAMP assay for detection of Salmonella typhi. In this LAMP assay, forward inner primer (FIP) and back inner primer (BIP) was specially designed for recognizing target invA gene. Target DNA was amplified and visualized as ladder-like pattern of bands on agarose gel within 60 min under isothermal conditions at $65^{\circ}C$. When the sensitivity and reproducibility of LAMP were compared to general PCR, there was no difference of reproducibility but sensitivity of LAMP assay was more efficient than PCR (the detection limit of LAMP assay was 30 fg, while the PCR assay was 3 pg). These results indicate that the LAMP assay is a potential and valuable means for detection of Salmonella typhi, especially for its rapidity, simplicity and low cost.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 춘계학술대회논문집
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• pp.712-717
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• 2001

In order to modify flexible mode frequencies, finite element analysis is applied for a lens-holder in pick-up actuator. Several design parameters like shape and local dimension of a lens-holder were selected adequately and sensitivities of the design variables for vibration modes were obtained by FE analysis and this result was used for updating FE model. A sensitivity matrix between the natural frequencies and the design variables was calculated by finite difference method. By comparing the calculated natural frequencies with target frequencies, modification of the design variables was acquired and used for improving FE model. Calculated natural frequencies after several iterations by FE analysis coincided with target frequencies and the errors between them were minimized.

• 대한기계학회논문집B
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• 제25권8호
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• pp.1030-1036
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• 2001

A new mathematical model to determine the optimal gas temperatures in reheating furnace was proposed for the good quality of products. This model employs sensitivity method to calculate the optimal gas temperatures in each zone for heating the slab up to its discharging target temperature and for heating it uniformly. This method was validated by showing that the calculated discharging temperature of the slab was in a good agreement with its prescribed discharging target one through an off-line simulation.

• 한국축산식품학회지
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• 제34권5호
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• pp.717-723
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• 2014

A rapid and specific PCR assay for the simultaneous detection of Listeria monocytogenes, Escherichia coli O157:H7, Bacillus cereus, Salmonella spp., and Staphylococcus aureus in foods was developed to reduce the detection time and to increase sensitivity. Multiplex PCR developed in this study produced only actA, fliC, hbl, invA, ileS amplicons, but did not produce any non-specific amplicon. The primer sets successfully amplified the target genes in the multiplex PCR without any non-specific or additional bands on the other strains. The multiplex PCR assays also amplified some target genes from five pathogens, and multiplex amplification was obtained from as little as 1 pg of DNA. According to the results from the sensitivity evaluation, the multiplex PCR developed in this study detected 10 cells/mL of the pathogens inoculated in milk samples, respectively. The results suggested that multiplex PCR was an effective assay demonstrating high specificity for the simultaneous detection of five target pathogens in food system.

• Parasites, Hosts and Diseases
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• 제47권3호
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• pp.293-297
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• 2009

Improved methods for detection of Cryptosporidium oocysts in environmental and clinical samples are urgently needed to improve detection of cryptosporidiosis. We compared the sensitivity of 7 PCR primer sets for detection of Cryptosporidium parvum. Each target gene was amplified by PCR or nested PCR with serially diluted DNA extracted from purified C. parvum oocysts. The target genes included Cryptosporidium oocyst wall protein (COWP), small subunit ribosomal RNA (SSU rRNA), and random amplified polymorphic DNA. The detection limit of the PCR method ranged from $10^3$ to $10^4$ oocysts, and the nested PCR method was able to detect $10^0$ to $10^2$ oocysts. A second-round amplification of target genes showed that the nested primer set specific for the COWP gene proved to be the most sensitive one compared to the other primer sets tested in this study and would therefore be useful for the detection of C. parvum.

• Structural Engineering and Mechanics
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• 제68권2호
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• pp.159-170
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• 2018

This paper aims to develop response modification factors for stiffness degrading structures by incorporating soil-structure interaction effects. A comprehensive parametric study is conducted to investigate the effects of key SSI parameters, natural period of vibration, ductility demand and hysteretic behavior on the response modification factor of soil-structure systems. The nonlinear dynamic response of 6300 soil-structure systems are studied under two ensembles of accelograms including 20 recorded and 7 synthetic ground motions. It is concluded that neglecting the stiffness degradation of structures can results in up to 22% underestimation of inelastic strength demands in soil-structure systems, leading to an unexpected high level of ductility demand in the structures located on soft soil. Nonlinear regression analyses are then performed to derive a simplified expression for estimating ductility-dependent response modification factors for stiffness degrading soil-structure systems. The adequacy of the proposed expression is investigated through sensitivity analyses on nonlinear soil-structure systems under seven synthetic spectrum compatible earthquake ground motions. A good agreement is observed between the results of the predicted and the target ductility demands, demonstrating the adequacy of the expression proposed in this study to estimate the inelastic demands of SSI systems with stiffness degrading structures. It is observed that the maximum differences between the target and average target ductility demands was 15%, which is considered acceptable for practical design purposes.

• 센서학회지
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• 제21권5호
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• pp.345-351
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• 2012

Biomimetic terpene sensors which have high sensitivity and stability have been fabricated using moleculary imprinted polymer (MIP) technology. Since it is impossible to make a resistive type sensor due to the high resistance of MIP, we improved the sensor by adding conductive polymers. We investigated the sensitivity of resistive type sensors with nano particles depending on the amount of conductive polymers. The MIP membrane contained the methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross linker, which formed specific cavities originated by the target terpene molecules. The mixture of MIP and the conductive polymer was coated on the patterns of interdigit electrodes on the alumina substrate. The fabricated sensors showed their highest specific sensitivities exposed to 500 ppm target gases : limonene 0.055 at 40% of amount of conductive polymers and geraniol $5.84{\times}10^{-4}$ at 20% of amount of conductive polymers. In conclusion, we found that the terpene sensors are affected by the target molecules, functional monomers and the conductive polymers.

• International Journal of Aeronautical and Space Sciences
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• 제2권2호
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• pp.73-81
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• 2001

This paper describes the procedure to develop a robust estimator design method for a target tracker that accounts for both structured real parameter uncertainties and unknown inputs. Two robust design approaches are combined: the Mini-p-Norm. design method to consider real parameter uncertainties and the $H_{\infty}$ design technique for unknown disturbances and unknown inputs. Constant estimator gains are computed that guarantee the robust performance of the estimator in the presence of parameter variations in the target model and unknown inputs to the target. The new estimator has two design parameters. One design parameter allows the trade off between small estimator error variance and low sensitivity to unknown parameter variations. Another design parameter allows the trade off between the robustness to real parameter variations and the robustness to unknown inputs. This robust estimator design method was applied to the longitudinal motion tracking problem of a T-38 aircraft.