• Advances in aircraft and spacecraft science
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• v.1 no.2
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• pp.233-251
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• 2014

Each aircraft have to be certified for a specified level of impact energy, for assuring the capability of a safe flight and landing after the impact against a bird at cruise speed. The aim of this research work was to define a scientific and methodological approach to the study of the birdstrike phenomenon against several windshield geometries. A series of numerical simulations have been performed using the explicit finite element solver code LS-Dyna, in order to estimate the windshield-surround structure capability to absorb the bird impact energy, safely and efficiently, according to EASA Certification Specifications 25.631 (2011). The research considers the results obtained about a parametric numerical analysis of a simplified, but realistic, square flat windshield model, as reported in the last work (Grimaldi et al. 2013), where this model was subjected to the impact of a 1.8 kg bird model at 155 m/s to estimate the sensitivity of the target geometry, the impact angle, and the plate curvature on the impact response of the windshield structure. Then on the basis of these results in this paper the topic is focused about the development of a numerical simulation on a complete aircraft windshield-surround model with an innovative configuration. Both simulations have used a FE-SPH coupled approach for the fluid-structure interaction. The main achievement of this research has been the collection of analysis and results obtained on both simplified realistic and complete model analysis, addressed to approach with gained confidence the birdstrike problem. Guidelines for setting up a certification test, together with a design proposal for a test article are an important result of such simulations.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.14 no.2
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• pp.95-107
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• 2002

A reliability analysis on sliding of monolithic vertical caisson of composite breakwaters is extensively carried out in order to make the basis for the applicability of reliability-based design method. The required width of caisson of composite breakwaters is determined by the deterministic design method including the effect of impulsive breaking waves as a function of water depth, also studied interactively with the results of reliability analyses. It is found that the safety factor applied in current design may be a little over-weighted magnitude for the sliding of caisson. The reliability index/failure probability is also seen to slowly decrease as the water depth increases for a given wave condition and a safety factor. In addition, optimal safety factor can roughly be evaluated by using the concept of target reliability index for several incident waves. The variations of optimal safety factor may be resulted from the different wave conditions. Finally, it may be concluded from the sensitivity studies that the reliability index may be more depended on the incident wave angles and the wave periodsrather than on the bottom slopes and the thickness of rubble mound.

• Journal of Ginseng Research
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• v.44 no.2
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• pp.238-246
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• 2020

Background: Dietary fat has been suggested to be the cause of various health issues. Obesity, hypertension, cardiovascular disease, diabetes, dyslipidemia, and kidney disease are known to be associated with a high-fat diet (HFD). Obesity and associated conditions, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), are currently a worldwide health problem. Few prospective pharmaceutical therapies that directly target NAFLD are available at present. A Traditional Chinese Medicine, ginseng-plus-Bai-Hu-Tang (GBHT), is widely used by diabetic patients to control glucose level or thirst. However, whether it has therapeutic effects on fat-induced hepatic steatosis and metabolic syndrome remains unclear. Methods: This study was conducted to examine the therapeutic effect of GBHT on fat-induced obesity, hepatic steatosis, and insulin resistance in mice. Results: GBHT protected mice against HFD-induced body weight gain, hyperlipidemia, and hyperglycemia compared with mice that were not treated. GBHT inhibited the expansion of adipose tissue and adipocyte hypertrophy. No ectopic fat deposition was found in the livers of HFD mice treated with GBHT. In addition, glucose intolerance and insulin sensitivity in HFD mice was also improved by GBHT. Conclusion: GBHT prevents changes in lipid and carbohydrate metabolism in a HFD mouse model. Our findings provide evidence for the traditional use of GBHT as therapy for the management of metabolic syndrome.

• Archives of Pharmacal Research
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• v.24 no.3
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• pp.207-210
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• 2001

A fully automated high performance liquid chromatography with column-switching was developed for the simultaneous determination of KR60436, a new reversible proton pump inhibitor, and its active metabolite O-Demethyl-KR60436 from rat plasma samples. Plasma sample (50$\mu$l) was directly introduced onto a Capcell Pak MF Ph-1 column ($10{\times}4$ mm I.D.) where primary separation was occurred to remove proteins and concentrate target Substances Using acetonitrile-Potassium Phosphate (PH 7, 0.1 M) (2 : 8, v/v). The drug molecules eluted from MF Ph-1 column were focused in an intermediate column ($10{\times}2$ I.D.) by the valve switching step. The substances enriched in intermediate column were eluted and separated on a Vydac 218MR53 column ($250{\times}3.2$ I.D.) using acetonitrilepotassium phosphate (pH 7, 0.02 M) (47:53, v/v) at a flow rate of 0.5 ml/min when the valve status was switched back to A position. The method showed excellent sensitivity (detection limit of 2 ng/ml) with small volume of samples ($50{\mu}$l), good precision and accuracy, and speed (total analysis time 24 min) without any loss in chromatographic efficiency. The response was linear ($r^2{\geq}0.797$) over the concentration range of 5-500 ng/ml.

• Journal of the Korean Society for Railway
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• v.19 no.2
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• pp.187-194
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• 2016

It is necessary to determine reliability indexes of existing railway bridges prior to setting up a proper target reliability index that can be used to introduce a reliability based limit state design method to design practice. Reliability is evaluated for a six PSC-I girder railway bridge, which is one of many representative types of double-track railway bridges. The reliability assessment is carried out for an edge girder subjected to bending moment. In the assessment, the flexural resistance and the fixed-load effect were obtained using existing statistical values from previous research on the introduction of limit state design to road bridge design. On the other hand, the live-load effect was determined using statistical values obtained from field measurement for the Joong-ang corridor, on which heavy freight trains are frequently passing. The reliability assessment is performed by AFOSM(Advanced First Order Second Moment method) for the limit state equation, and a sensitivity analysis for the reliability is performed for each factor of the load and resistance effects.

• The Korean Journal of Pain
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• v.27 no.2
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• pp.178-185
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• 2014

Epidural adhesions cause pain by interfering with the free movement of the spinal nerves and increasing neural sensitivity as a consequence of neural compression. To remove adhesions and deliver injected drugs to target sites, percutaneous epidural adhesiolysis (PEA) is performed in patients who are unresponsive to conservative treatments. We describe four patients who were treated with a newly developed inflatable balloon catheter for more effective PEA and relief of stenosis. In the present patients, treatments with repetitive epidural steroid injection and/or PEA with the Racz catheter or the NaviCath did not yield long-lasting effects or functional improvements. However, PEA and decompression with the inflatable balloon catheter led to maintenance of pain relief for more than seven months and improvements in the functional status with increases in the walking distance. The present case series suggests that the inflatable balloon catheter may be an effective alternative to performing PEA when conventional methods fail to remove adhesions or sufficiently relieve stenosis.

• Analytical Science and Technology
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• v.13 no.1
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• pp.72-80
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• 2000

The HS/GC/MS method was performed to analyze the volatile organic compounds in waste sludge samples. This study was performed to establish the fundamental data by studying the effects of salt, equilibrium temperature and time in the volatile organic compounds analysis. The presence of salts have been found to increase the sensitivity. The peak area is increased from 1.07 to 2.61 times by adding the salts to the water sample, compared with a salt tree sample. The recoveries of target compounds have found between 90% and 127% at sample temperature of $85^{\circ}C$ for 30 min. This HS/GC/MS method can be applied to analyze the volatile organic compounds and organohalo compounds in the environmental matrix.

• Journal of Fashion Business
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• v.13 no.4
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• pp.178-190
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• 2009

The purpose of this study is to make reference for geometric fashion by investigating geometric patterns by linear types and to propose high value added print and fashion design by designing and producing geometric prints and apparel with them focusing on digital textile printing. As a method of the study, visual and textural data were investigated for theory of geometric pattern and fashion design samples were illustrated. The geometric pattern could be defined as abstract pattern which was crossed with straight line or curve. We could group it into three classes such as straight linear, curved, and mixed type. Images varied with linear types. The image of straight linear type was sharp and modern, that of curved one was soft and feminine and that of mixed one was gorgeous and artistic. And then, 3 geometric prints and 3 one-pieces were designed. The concept of design was simple optimism which was based on sixties. Target was young optimistic women group from the mid teens to the mid twenties who continued to seek after their unique individuality keeping their modern lifestyle. Geometric patterns with straight linear, curved, and mixed type were designed and dresses which went well with them were designed and produced. According to the result of this study, images of geometric fashion can be represented diversely by varying linear type, digital textile printing is good method for high value added geometric fashion because of its high quality and degree of sensitivity, and geometric pattern is a good source for contemporary fashion.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.46 no.2
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• pp.173-183
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• 2010

In a split beam echo sounder, the transducer design needs to have minimal side lobes because the angular position and level of the side lobes establishes the usable signal level and phase angle limits for determining target strength. In order to suppress effectively the generation of unwanted side lobes in the directivity pattern of split beam transducer, the spacing and size of the transducer elements need to be controlled less than half of a wavelength. With this purpose, a 50 kHz tonpilz type transducer with a half-wavelength diameter in relation to the development of a split beam transducer was designed using the equivalent circuit model, and the underwater performance characteristics were measured and analyzed. From the in-air and in-water impedance responses, the measured value of the electro-acoustic conversion efficiency for the designed transducer was 51.6%. A maximum transmitting voltage response (TVR) value of 172.25dB re $1{\mu}Pa/V$ at 1m was achieved at 52.92kHz with a specially designed matching network and the quality factor was 10.3 with the transmitting bandwidth of 5.14kHz. A maximum receiving sensitivity (SRT) of -183.57dB re $1V/{\mu}Pa$ was measured at 51.45kHz and the receiving bandwidth at -3dB was 1.71kHz. These results suggest that the designed tonpilz type transducer can be effectively used in the development of a split beam transducer for a 50kHz fish sizing echo sounder.

• The Journal of the Korea Contents Association
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• v.9 no.6
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• pp.126-133
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• 2009

This study examined the relationship of what kind of creative thinking has as factors for emotion design products for consumers focusing on the successful cases of emotion products. For the design creativity attribute used in this experiment, the design evaluation creativity tools revealed in Kim Eun-Ju's 2007 design creativity evaluation tool development were used mostly MP3s, which have various forms, functions and sizes were selected as the target for experiment. Results of the experiment showed that for design creativeness items for MP3 as single products, uniqueness, favorableness and convenience were relevant. Accordingly, the common features of design creativeness items for emotional products were identified. According to the result, for emotional designs, the interest level of uniqueness for the design creativity evaluation items and the functional items for practicality had a high relativity. Therefore, there is a need to examine the common features between the design creativity items for products other than MP3s in the future.