• Journal of Forest and Environmental Science
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• v.34 no.3
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• pp.246-248
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• 2018

Urban development and population have augmented the increase of impervious land-cover. This phenomenon has amplified the effects of climate change and increasing urban island effects due to increases in urban temperatures. Seoul, South Korea is one of the largest metropolitan cities in the world. While land uses in Seoul vary, land cover patterns have not changed much (under 2%) in the past 10 years, making the city a prime target for studying the effects of land cover types on the urban temperature. This research seeks to generalize the urban temperature of Seoul through a series of statistical tests using multi-temporal remote sensing data focusing on multiple scales and typologies of green space to determine its overall effectiveness in reducing the urban heat. The distribution of LST values was reduced as the size of urban forests increased. It means that changing temperature of large-scale green-spaces is less influenced because the broad distribution could be resulted in various external variables such as slope aspect, topographic height and density of planting areas, while small-scale urban forests are more affected from that. The large-scale green spaces contributed significantly to lowering urban temperature by showing a similar mean LST value. Both of concentration and dispersal of urban forests affected the reduction of urban temperature. Therefore, the findings of this research support that creating urban forests in an urban region could reduce urban temperature regardless of the scale.

• Journal of the Society of Naval Architects of Korea
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• v.53 no.4
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• pp.266-274
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• 2016

Many researchers have been trying to improve the propulsion efficiency of a propeller. In this study, the numerical analysis is carried out for the POW(Propeller Open Water test) performance of a propeller equipped with an energy saving device called PHVC(Propeller Hub Vortex Control). PHVC is aimed to control the propeller hub vortex behind the propeller so that the rotational kinetic energy loss can be reduced. The unsteady Reynolds Averaged Navier-Stokes(URANS) equations are assumed as the governing flow equations and are solved by using a commercial CFD(Computational Fluid Dynamics) software, where SST k-ω model is selected for turbulence closure. The computed characteristic values, thrust, torque and propulsion efficiency coefficients for the target propeller with and without PHVC and the local flows in the propeller wake region are validated by the model test results of KRISO LCT(Large Cavitation Tunnel). It is concluded from the present numerical results that CFD can be a good promising method in the assessment of the hydrodynamic performance of PHVC in the design stage.

• Journal of Korean Society on Water Environment
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• v.31 no.1
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• pp.1-11
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• 2015

In this study, the attraction efficiency of the by-pass fishway installed at Dalseong Weir in Nakdong River was assessed according to operation of the attraction waterway by using River2D which is a two-dimensional physical habitat simulation model. The model was calibrated and validated through the measured water elevation. The attraction efficiency of the fishway was evaluated at the low flow condition because the target fish, Zacco platypus (Z. platypus), have moved frequently up and downstream at the spawning season from April to June. From simulation results, it can be deduced that the attraction efficiency at situation of open attraction waterway is superior to that of close attraction waterway. Also it is shown that velocity field at inner region of the fishway is suitable for migration of the fish.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.1
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• pp.65.2-65.2
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• 2010

We present a result of $^{13}CO$(1-0) survey toward the Outer Galactic Plane using the multi-beam receiver system recently installed on the 14 m telescope at Taeduk Radio Astronomy Observatory(TRAO). Our first target region is from $l=108^{\circ}$ to $113^{\circ}$ and $b=-1^{\circ}$ to $+1^{\circ}$, and some extended regions are included where emission is still arising. All data are on 50" grid. Velocity resolution is 0.63 km/sec, and the total velocity range is from -150 km/sec to 100 km/sec. A total of 40,000 spectra were obtained. The rms noise is about 0.2 K per channel for unsmoothed raw data. We will present a few initial results of the survey database.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.2
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• pp.82.1-82.1
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• 2010

We have investigated the spatial configuration of stars within the tidal radius of metal poor globular cluster NGC 6626 in the bulge direction. Data were obtained in near-IR J,H,Ks bands with wide-field ($20'\times20'$) detector, WIRCam at CFHT. To trace the stellar density around target cluster, we sorted cluster's member stars by using a mask filtering algorithm and weighting the stars on the color-magnitude diagram. From the weighted surface density map, we found that the stellar spatial distributions within the tidal radius appear asymmetric and distorted features. Especially, we found that more prominent over-density features are extending toward the direction of Galactic plane rather than toward the directions of the Galactic center and its orbital motion. This orientation of the stellar density distribution can be interpreted with result of disk-shock effect of the Galaxy that the cluster had been experienced. Indeed, this over-density feature are well represented in the radial surface density profile for different angular sections. As one of the metal poor globular clusters with extended horizontal branch (EHB) in the bulge direction, NGC 6626 is kinematically decoupled from the normal clusters and known to have disk motion of peculiar motion. Thus, our result will be able to add further constraints to understand the origin of this cluster and the formation of bulge region in early universe.

• Journal of the Korean Society of Safety
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• v.30 no.6
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• pp.102-109
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• 2015

In this study, on the basis of the results of the field survey and the theoretical consideration for Korean Standard Specification for concrete durability and maintenance, the following conclusions are derived. From the survey, the prediction equation of carbonation depth for the southwest region in Korea is experimentally proposed, $y_p=5.865{\sqrt{t}}$, which predicts about 60mm of the carbonation depth for the concrete structures of 100 years, a 1st class of target endurance period, under a combined deterioration environment like a marine environment. Considering that the marginal value for a carbonation depth limitation under very severely marine environment is 25mm, in accordance with the Specification, it is found that the predicting carbonation depth for the concrete cover depths, 100mm and 60mm are 63mm and 29.4mm, respectively. In conclusion, according to the equation and the Specification, it is strongly required that the reinforced concrete structures with the cover depth under 100mm have to make a protection from combined deterioration factors by any methods like a surface coating, an increment of cover depth or an application of a special concrete.

• BMB Reports
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• v.49 no.10
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• pp.578-583
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• 2016

Special AT-rich sequence binding protein 1 (SATB1) is a nuclear matrix-associated DNA-binding protein that functions as a chromatin organizer. SATB1 is highly expressed in aggressive breast cancer cells and promotes growth and metastasis by reprograming gene expression. Through genome-wide cross-examination of gene expression and histone methylation, we identified SATB1 target genes for which expression is associated with altered epigenetic marks. Among the identified genes, long noncoding RNA urothelial carcinoma-associated 1 (UCA1) was upregulated by SATB1 depletion. Upregulation of UCA1 coincided with increased H3K4 trimethylation (H3K4me3) levels and decreased H3K27 trimethylation (H3K27me3) levels. Our study showed that SATB1 binds to the upstream region of UCA1 in vivo, and that its promoter activity increases with SATB1 depletion. Furthermore, simultaneous depletion of SATB1 and UCA1 potentiated suppression of tumor growth and cell survival. Thus, SATB1 repressed the expression of oncogenic UCA1, suppressing growth and survival of breast cancer cells.

• 한국전산유체공학회:학술대회논문집
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• 1999.11a
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• pp.77-84
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• 1999

Numerical design optimization techniques are implemented for the improvement of the ram accelerator performance. The design object is to find the minimum ram tube length required to accelerate projectile from initial velocity $V_0$ to target velocity $V_e$. The premixture is composed of $H_2,\;O_2,\;N_2$ and the mole numbers of these species are selected as design variables. The objective function and the constraints are linearized during the optimization process and gradient-based Simplex method and SLP(Sequential Linear Programming) have been employed. With the assumption of two dimensional inviscid flow for internal flow field, the analyses of the nonequilibrium chemical reactions for 8 steps 7 species lave been performed. To determined the tube length, ram tube internal flow field is assumed to be in a quasi-steady state and the flow velocity is divided into several subregions with equal interval. Hence the thrust coefficients and accelerations for corresponding subregions are obtained and integrated for the whole velocity region. With the proposed design optimization techniques, the total ram tube length had been reduced $19\%$ within 7 design iterations. This optimization procedure can be directly applied to the multi-stage, multi-premixture ram accelerator design optimization problems.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1685-1689
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• 2016

Physical wedges still can be used as missing tissue compensators or filters to alter the shape of isodose curves in a target volume to reach an optimal radiotherapy plan without creating a hotspot. The aim of this study was to investigate the dosimetric properties of physical wedges filters such as off-axis photon fluence, photon spectrum, output factor and half value layer. The photon beam quality of a 6 MV Primus Siemens modified by 150 and 450 physical wedges was studied with BEAMnrc Monte Carlo (MC) code. The calculated present depth dose and dose profile curves for open and wedged photon beam were in good agreement with the measurements. Increase of wedge angle increased the beam hardening and this effect was more pronounced at the heal region. Using such an accurate MC model to determine of wedge factors and implementation of it as a calculation algorithm in the future treatment planning systems is recommended.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.917-923
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• 2014

Chondrosarcomas are malignant cartilage-forming tumors of bone which exhibit resistance to both chemotherapy and radiation treatment. miRNAs have been well demonstrated to regulate gene expression and play essential roles in a variety of biological processes, including proliferation, differentiation, migration, cell cycling and apoptosis. In this study, we obtained evidence that miR-100 acts as a tumor suppressor in human chondrosarcomas. Interestingly, cisplatin resistant chondrosarcoma cells exhibit decreased expression of miR-100 compared with parental cells. In addition, we identified mTOR as a direct target of miR-100. Overexpression of miR-100 complementary pairs to the 3' untranslated region (UTR) of mTOR, resulted in sensitization of cisplatin resistant cells to cisplatin. Moreover, recovery of the mTOR pathway by overexpression of S6K desensitized the chondrosarcoma cells to cisplatin, suggesting the miR-100-mediated sensitization to cisplatin dependent on inhibition of mTOR. In summary, the present studies highlight miR-100 as a tumor suppressor in chondrosarcoma contributing to anti-chemoresistance. Overexpression of miR-100 might be exploited as a therapeutic strategy along with cisplatin-based combined chemotherapy for the treatment of clinical chondrosarcoma patients.