• The Journal of the Korea Contents Association
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• v.12 no.5
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• pp.103-112
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• 2012

This paper is based on the perspective that the YTN Science, a science channel in Korea which plays a key role in the popularization of science, is suffering from low viewing ratings, insufficient content, and shortage of production. First, this study employs an exploratory method to identify current status of programming and operation of the Korean science channel along with its promotional strategy. Second, it aims to conduct an analysis on the science channels, specifically some major programs, of other nations including the U.S. (Discovery Channel, National Geographic Channel), United Kingdom (BBC Knowledge), Japan (Science Channel), and China (CCTV 10), seeking the possibility to apply and combine them afterward to the Korean TV channels specialized in science. A number of implications are derived from our diagnosis of present situation and analysis of abroad cases, and this helps us suggest the content development and promotional strategies as follows: First, due to the rising need for change in the programming strategy to enhance the value of the content, it is required to rearrange the programming in terms of the target audience and the viewer lifestyle, adopt a new strategy for building up the viewers' watching habit through 'stripping', and place strategic programs in prime-time. Second, as for the specific schemes of content production and application, it is recommended to establish a dual strategy in creating the content (one for conveying knowledge, the other for delivering fun), plan and use a representative character of the program, select scientific and technological topics with more Korean backgrounds, attempt strategic ties with SNS, deepen and diversify the material for programs, and implement a strategy to boost the OSMU. Finally, with regard to the promotional strategy, a constructive proposal may include raising channel awareness through science-related events and live broadcasting, performing promotional strategies by way of expanding to printed media like magazine and book publications, and intensifying online and mobile promotional strategy.

• Journal of the Korean Society for Nondestructive Testing
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• v.27 no.1
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• pp.31-37
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• 2007

A $^{192}Ir$ small-focal source has been developed by using the HANARO reactor and the radioisotope production facility at the Korea Atomic Energy Research Institute (KAERI). The small-focal source with the dimension of 0.5 mm in diameter and 0.5 mm in length was fabricated as an aluminum-encapsulated form by a specially designed pressing equipment. For the estimation of the radioactivity, neutron self-shielding and ${\gamma}-ray$ self-absorption effects on the measured activity was considered. From this estimation, it is realized that $^{192}Ir$ small-focal sources over 3 Ci activities can be produced from the HANARO. Field performance tests were performed by using a conventional source and the developed source to take images of a computer CPU and a piece of a carbon steel. The small-focal source showed better penetration sensitivity and geometrical sharpness than the conventional source does. It is concluded from the tests that the focal dimension of this source is small enough to maximize geometrical sharpness in the image taking for the close proximity shots, pipeline crawler applications and contact radiography.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.1
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• pp.48-54
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• 2007

Bacillus polyfermenticus SCD (B. polyfermenticus SCD) has been appropriately used for the therapy of long-term intestinal disorders, because live strains in the form of active endospores can successfully reach the target intestine in humans. B. polyfermenticus SCD produces the most antibiotic-related materials. In the present study, B. polyfermenticus SCD was fermented with soybeans (BPFS) and its probiotic properties were investigated. B. polyfermenticus SCD and BPFS showed a broad spectrum of antimicrobial activity against pathogenic Gram-positive (Streptococcus parauberis, Streptococcus iniae, Lactococcus garviae) and Gram-negative (Flexibacter tractuosus, Vibrio harveyi, Vibrio vulnificus, Vibrio ordalii) bacteria and moulds (Aspergillus niger, Aspergillus oryzae). Sebastes schlegeli were used to examine survival rate and cleanup action by BPFS. Bacterial infection resulted in a mortality of up to 99% in the commercial fodder fed groups. BPFS both enhanced the growth rate of fry by improving their appetite and had cleaned by decreased eutrophication. Therefore, it seems appropriate that BPFS should be developed as an antibiotic replacement, favorable fodder additive, and antifungal material in fish farming systems.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4031-4036
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• 2012

Background: The negative signaling provided by interactions of the co-inhibitory molecule, programmed death-1 (PD-1), and its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2), is a critical mechanism contributing to tumor evasion; blockade of this pathway has been proven to enhance cytotoxic activity and mediate antitumor therapy. Here we evaluated the anti-tumor efficacy of AAV-mediated delivery of the extracellular domain of murine PD-1 (sPD-1) to a tumor site. Material and Methods: An rAAV vector was constructed in which the expression of sPD-1, a known negative regulator of TCR signals, is driven by human cytomegalovirus immediate early promoter (CMV-P), using a triple plasmid transfection system. Tumor-bearing mice were then treated with the AAV/sPD1 construct and expression of sPD-1 in tumor tissues was determined by semi quantitative RT-PCR, and tumor weights and cytotoxic activity of splenocytes were measured. Results: Analysis of tumor homogenates revealed sPD-1 mRNA to be significantly overexpressed in rAAV/sPD-1 treated mice as compared with control levels. Its use for local gene therapy at the inoculation site of H22 hepatoma cells could inhibit tumor growth, also enhancing lysis of tumor cells by lymphocytes stimulated specifically with an antigen. In addition, PD-1 was also found expressed on the surfaces of activated CD8+ T cells. Conclusion: This study confirmed that expression of the soluble extracellular domain of PD-1 molecule could reduce tumor microenvironment inhibitory effects on T cells and enhance cytotoxicity. This suggests that it might be a potential target for development of therapies to augment T-cell responses in patients with malignancies.

• The Journal of the Convergence on Culture Technology
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• v.6 no.3
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• pp.401-412
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• 2020

This study analyzed the causes of warehouse fires using a creative problem-solving technique called TRIZ. It identified preventive measures by applying 4M. The results are as follows. First, this study examined the inconsistency among the causes of warehouse fires using TRIZ. Second, it analyzed human factors and fire prevention measures in warehouses such as safety standards for managers, and methods for the promotion of safety consciousness among workers, and for the reinforcement of construction technology for sandwich panel workers. Third, it identified the mechanical and facility factors and fire prevention measures in warehouses such as safety facilities, the expanded installation of safety devices, the adoption and development of fire suppression equipment, and the deployment of methods to improve the fire resistance of sandwich panels. Fourth, it presented working and environmental factors and fire prevention measures in warehouses such as the tightening of safety precautions and the supervision of working methods, and setting fire partitions both in loading places and based on performance-based design. Finally, it proposed managerial factors and fire prevention measures in warehouses such as specific targeting for firefighting with low fire hazards, reviewing the material quality regulations of non-combustible or higher for sandwich panels in the specific target of firefighting that cannot apply fire safety standards, installing sprinklers in cold storage, and mandating the installation of automated facilities with retroactive application regardless of the floor area in the warehouse with a sandwich panel structure.

• Journal of Digital Convergence
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• v.12 no.2
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• pp.423-430
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• 2014

Patient safety culture for the general hospital to investigate the perception of radiological technologists, managing of the patient safety provides the Foundation for the safety activities as a basis to develop a program for providing. Patient safety culture for the general hospital to investigate the perception of Radiological technologists, the duration of the survey of the study on June 13, 2012 to June 20, and five general hospitals worked on Radiological technologists workers were material and analyzed the target of 198 (SPSS ver. 19.0). Patient safety activities within the Department, the factors affecting direct care, communication, medical malpractice, hospitals rated, safe for the patient safety culture and the reported accidents, dangerous and caused an accident, most feel that patient safety incident reporting system according to the results of evaluating medical accidents patient safety culture regarding recognition, work appeared in more than 25 years, even the most highly evaluated, the working period of 10 patient safety to 15 years the most highly. Therefore, General Hospital, Director of the patient safety culture improvement of radiation in order to have sufficient staffing, aggressive approach to patient safety issues, and safe working period of relapse prevention of accidents to the radiation as well as giving systematic consideration of mission medical accident reporting system will be active.

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.559-568
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• 2009

Objectives : In order to manage to reformative tendency of the educational whole with change request of dental hygienics education which is diversificated and professionalized the manufacturing practice of a temporary resin jacket which is educated with from much dental hygiene is become accomplished, so far also the recognition which relates with the manufacturing practice of a temporary resin jacket of dental hygiene students there is not researched. The present research carried out the practice evaluation with the target of students of a dental hygiene department, who finished a manufacturing practice of a temporary resin jacket, analyzed and investigated the material, reported its result, and enforced a research. Methods : This research selected students of 6 dental hygiene departments located in the Daegu Gyeongbuk region, who have manufacturing experience of a temporary resin jacket, by a convenient sampling method, and then a questionnaire was executed by a self-administration method, and a total of 290 copies were statistically treated. The content of the questionnaire are composed of 2 questions on an attitude survey before and after manufacturing practice of a temporary resin jacket, 3 questions on an educator for practice of a temporary resin jacket, 7 questions on recognition of technical skills for manufacturing a temporary resin jacket, 9 questions on the practice content evaluation of manufacturing of a temporary resin jacket and recognition on manufacturing practice of a the temporary resin jacket. Results : 1. The average of recognition on technical skills for manufacturing a temporary resin jacket of a dental hygienist was 3.82 points, the average of evaluation on practice content of manufacturing a temporary resin jacket being 3.75 points, and the average of recognition on the practice of manufacturing a temporary resin jacket was 3.71 points. 2. Currently, as the educator for the practice of manufacturing a temporary resin jacket, dental hygienists were 188 persons(64.8%) and dental technicians was 102 persons(35.2%), and as educators they want in the future, dental hygienists were 97 persons(33.3%) and dental technicians was 193 persons(66.7%). Persons hoping reeducation for manufacturing a temporary resin jacket were 219 persons(85.9%). 3. There was a significant difference in consciousness of students before and after practice of manufacturing a temporary resin jacket(p<.001). 4. There was a significant difference in practice evaluation and practice recognition according to the educational subject(p<.001). 5. There was a significant reverse correlation in the educational subject, practice evaluation and practice recognition(p<0.01). Conclusions : The practice for manufacturing a temporary resin jacket in education of dental hygiene is necessary to improve job performance ability in more various and specialized dental treatment and to solve desire for improvement of professional technical skill ability of students, and accordingly. About study process of the future students observation investigation or student objective interview investigation etc. seeks a problem in the become research lead, the succeeding research which gropes the plan which is the possibility of solving the problem which discovered is thought will be necessary.

• Tuberculosis and Respiratory Diseases
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• v.56 no.2
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• pp.169-177
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• 2004

Background : Cyclooxygenase is the main target enzyme for the nonsteroidal anti inflammatory drugs (NSAIDs) that have been shown to suppress carcinogenesis in both experimental models and epidemiological studies. COX-2 plays an important role in solid tumor growth, invasiveness and angiogenesis, through, in part, the synthesis of prostaglandins, such as prostaglandin E2 (PGE2). In this study, the prognostic significance of an increase in COX-2 expression in lung cancer samples was evaluated. Material and Methods : The expression of COX-2, by immunohistochemistry, was studied in paraffin-embedded tumor blocks obtained from 84 patients(male 67, female 17, with a mean age of 63, ranging from 34 to 84 years) who had undergone surgery at Wonkwang University Hospital, between 1997 and 2002. For the evaluation of the relationships between COX-2 expression, and the clinical stage, metastasis to lymph nodes and survival, those cases showing the respective antigen expression in >10% of the tumor cells were considered positive. Result : Of the 84 patients, 61 (73%) exhibited more than 10% COX-2 immunoreactivities in the tumor and normal cells, whereas the remaining 23 showed no increase in the expression of COX-2. There was no significant relationship between the increased expression of COX-2 and the disease stage(p=0.1002) or cell type(p=0.152). The median survival was longer for the patients with a negative, compared to positive, COX-2 expression(36 compared to 24 months, p<0.05). The two year-survival rate was also higher in the patients with a negative COX-2 expression (78%) than those with a positive expression (47%, Kaplan-Meier, Log Rank, p < 0.05). Conclusion : The median survival was longer in the patients with a negative, compared to positive, COX-2 expression was longer than those with positive COX-2, having undergone complete resection due to primary non-small cell lung cancer.

• Journal of the Korean housing association
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• v.20 no.4
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• pp.113-120
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• 2009

The demands of residents can be predicted by analyzing the housing viewpoint of residents. And also, the housing viewpoint can change according to various environmental changes, so it's important for us to understand the trend of change. Therefore, the housing viewpoints of university students who will be subjective residents of houses in future were analyzed by observing change due to trend of time. Target for this study is female university students in 20s. A portion of previously presented material (Korean Home Economics Association 37,1, 67-78) was used as data for 1998 and a questionnaire with 171 female university students was conducted on December 2008 for data for 2008. The following result was drawn from examination of change in the housing viewpoint due to trend of time by comparing the housing viewpoint of university students between 1998 and 2008. First, importance of was decreased and importance of was increased in functions of residence. Second, regardless of the time passage, the most students thought and as their opinions on housing. And also, the most students considered a living room as the most important space inside of a house regardless of the time passage and the level of considering a living room as the most important space was more increased. Third, the level of consideration got higher with time in the selection of houses. , , , , , and had higher level of consideration regardless of time passage. Items of which level of consideration increased with time are , , , , , and , and items of which level of consideration decreased are and . Fourth, it can be understood that the level of satisfaction in housing got higher with time. And it can be said that , , , and were not increased in the level of satisfaction in housing compared with 10 years ago. Fifth, regardless of time passage, the level of satisfaction in housing was lower than the level of consideration in the event of selection of houses. As , , and had lower levels of satisfaction in the event of selection of houses compared with the levels of consideration, they have higher possibility of dissatisfaction in housing.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.9
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• pp.1093-1098
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• 2013

A single-crystal sapphire is used as a transparent bulletproof window material; however, few studies have investigated the dynamic behavior and fracture properties under high-speed impact. High-speed and high-resolution sequential images are required to study the interaction of the bullet with the brittle ceramic materials. In this study, a device is developed to capture the sequence of high-speed impact/penetration phenomena. This system consists of a speed measurement device, a microprocessor-based camera controller, and multiple CCD cameras. By using a linear array sensor, the speed-measuring device can measure a small (diameter: up to 1 2 mm) and fast (speed: up to Mach 3) bullet. Once a bullet is launched, it passes through the speed measurement device where its time and speed is recorded, and then, the camera controller computes the exact time of arrival to the target during flight. Then, it sends the trigger signal to the cameras and flashes with a specific delay to capture the impact images sequentially. It is almost impossible to capture high-speed images without the estimation of the time of arrival. We were able to capture high-speed images using the new system with precise accuracy.