• Title/Summary/Keyword: Target Water Level

Search Result 239, Processing Time 0.026 seconds

Toxicity Study of AS6, a Triterpenoid Derivative: 4-Week Repeated Oral Administration in Rats

  • Lee, Michael;Cha, Shin-Woo;Im, Doo-Hyun;Yang, Byung-Chul;Lim, Kwang-Hyeon;Cha, Kyung-Hoi;Kim, Jong-Choon;Chung, Moon-Koo;Han, Jung-Hee
    • Biomolecules & Therapeutics
    • /
    • v.11 no.1
    • /
    • pp.72-79
    • /
    • 2003
  • The present study was conducted to investigate the potential subacute toxicity of AS6, [(3$\beta$, 4$\alpha$)-3,23-dihydroxyurs-12-en-28-oic acid], by a 4-week repeated oral administration in Sprague-Dawley rats. To test the subacute toxicity, AS6 was administered once daily by gavage to rats at dose levels of 0, 250, 500, and 1000 mg/kg/day for 4 weeks. There were no treatment-related effects on mortality, clinical signs, body weight, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings, organ weights, and histopathology in any treatment group. In the condition of this study, target organ was not observed and the no-observed-adverse-effect level (NOAEL) was considered to be 1000 mg/kg/day for both male and female rats.

INTEGRATED OPTICAL MODEL FOR STRAY LIGHT SUPPRESSION AND END-TO-END PERFORMANCE SIMULATION FOR GOCI

  • Ham, Sun-Jeong;Lee, Jae-Min;Youn, Heong-Sik;Kang, Gm-Sil;Kim, Seong-Hui;Kim, Sug-Whan
    • Proceedings of the KSRS Conference
    • /
    • v.1
    • /
    • pp.274-277
    • /
    • 2006
  • KARI is currently developing a geostationary ocean color imager (GOCI) for COMS. We report the progress in integrated optical modeling and analysis for stray light suppression and the end-to-end instrument performance verification including in-orbit calibration. The Sun is modeled as the emitting light source and the selected area around Korean peninsular as the observation target that scatters the sun light towards GOCI in orbit. The optical ray tracing employing active geometric scaling was then used for precise characterization of the spatial and radiometric performance at the instrument focal plane. The analysis results show positive reduction in the simulated stray light level with the design improvement including baffles. It also indicates that the ray traced in-orbit radiometric performances are effective tools for the independent assessment of more traditional linear and quadratic equation based estimation of water leaving radiance. The concept of integrated GOCI optical model and the computational method are presented.

  • PDF

Four-week Oral Toxicity Study of DA-9601, an Antiulcer Agent of Artemisia spp. Extract, in Rats (애엽추출물 항궤양제 DA-9601의 랫드에 대한 4주 경구 반복투여 독성연구)

  • 김옥진;강경구;김동환;백남기;안병옥;김원배;양중익
    • Biomolecules & Therapeutics
    • /
    • v.4 no.4
    • /
    • pp.354-363
    • /
    • 1996
  • This study was conducted to investigate the repeated dose toxicity of DA-9601, an antiulcer agent of Artemisia app. extract, in rats. DA-9601 was administered orally once a day for 4 weeks to 10 males and 10 females per group at doses of 0(vehicle control), 125, 500 or 2000 mg/kg/day. Throughout the study, no treatment-related deaths and clinical signs were observed. In female rats receiving 125 mg/kg of DA-9601, water consumption increased slightly on day 4, 11 and 25. Hematological examination showed a decrease of MCV and an increase of PLT in male rats at the doses of 500 and 2000 mg/kg groups. Blood biochemistry revealed slight decreases of cholesterol, BUN and Na in male rats and decreases of total bilirubin and creatinine and slight increases of globulin and Cl in female rats. The organ weights at the end of 4 weeks showed slight changes in some organs of treated groups. But, all these changes were not considered to be of toxicological importance, because they did not show dose-response relationship and relevance to gross and microscopic findings. Histopathologically, abnormal treatment-related changes were not observed in any organ and target organs were not detected. On the basis of these results, the NOAEL(no-observed-adverse-effect level) of DA-9601 was estimated to be more than 2000 mg/kg/day under the conditions tested.

  • PDF

Groundwater Movement Analysis Using the WINFLOW Model (WINFLOW 모델을 이용한 지하수 유동해석)

  • 최윤영;안승섭;김재광
    • Magazine of the Korean Society of Agricultural Engineers
    • /
    • v.45 no.3
    • /
    • pp.103-115
    • /
    • 2003
  • This study examines groundwater movement system analysis and movement forecast algorithm using finite element method. The target is Cheongha-myeon area, Bukgu, Pohang-city which has many difficulties in water supply during drought period. From the comparison of the differences between obtained values by WINFlOW model and observed values, it is thought that groundwater head distribution under steady flow is reflected well at the level of reliability Groundwater movement of study area shows stable pattern from western watershed to eastern coastal area while flow path is dense and steep in the center of the coastal area. The results of particle tracing for each well show a comparatively straight line from the western boundary side to the observation position at the upper area of the well, and are analyzed as it diffuses according to getting closer to the coast at the lower area of the well. The result of effect circle examination attendant on pumping amount in study area shows variation tendency that groundwater head decreases at the side and the lower area more than at the upper area of the well when groundwater flows from west to east(coast). As mentioned above, satisfactory results of groundwater movement analysis using WINFlOW model, two dimensional groundwater movement analysis model, are obtained through the great decrease of physical uncertainty of groundwater movement system.

Wastewater Treatment Process Study for Used Diaper Recycling (사용 후 기저귀 재활용을 위한 폐수처리방안 연구)

  • Kim, Kyung Shin;Lee, Ho Sun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.47 no.2
    • /
    • pp.24-33
    • /
    • 2015
  • This study aims to suggest wastewater treatment options for diaper recycling by identifying characteristic analysis of wastewater from diaper recycling process and efficiency evaluation of wastewater treatment units. The wastewater characteristic analysis showed that the concentration of organic pollutants and ionic materials were very high comparing to seawater. Through the investigation of similar wastewater treatment, six treatment units were identified to reduce pollutants. It is found UF(ultra-filtration), DAF(dissolved air flotation), fenton oxidation, electro-coagulation and chemical-coagulation are effective in reducing organic pollutants while membrane system and ion exchanger are effective in reducing ionic materials. Even though the target of water quality should be secured in terms of managing organic pollutants level, the application of treatment unit for reducing ionic material needs lots of considerations. This result suggests that reuse of pulping wastewater after controlling organic pollutants is better than direct discharge of pulping wastewater. To select the appropriate wastewater treatment unit, an economic analysis about operation condition, wastewater flow, cost, efficiency should be considered.

Studies on the Sorption Characteristics of $^{137}Cs$ onto Granite and Tuff ($^{137}Cs$의 화강암 및 응회암에 대한 흡착특성에 관한 연구)

  • Cho, Young-Hwan;Hahn, Pil-Soo;Park, Sang-Won
    • Nuclear Engineering and Technology
    • /
    • v.27 no.1
    • /
    • pp.25-32
    • /
    • 1995
  • Batch sorption experiments were conducted to investigate the sorption characteristics of $^{137}$ Cs, known for the primary target of safety assessment in low-level radwaste disposal, onto domestic rocks such as Granite and Tuff. A response surface analysis method was applied to quantify the effect of 3 independent variables ([Cs], [Vol/Wt], [pH]) on the sorption. Ac a result, initial Cs concentration appeared to be the most important variable within the range of the study. A significant effect of [Vol/Wt] on Kd was observed. The sorption of Cs was pH-insignificant. The sorption extent of nuclides onto tuff was more significant than that onto granite. The pH-insignificant sorption behavior of Cs was discussed in terms of the surface electrical properties and the solution chemistry. The sorption tendency of nuclides onto geomedia studied was interpreted by adopting the water structure modification theory.

  • PDF

Study on Ship Detection Using SAR Dual-polarization Data: ENVISAT ASAR AP Mode

  • Yang, Chan-Su;Ouchi, Kazuo
    • Korean Journal of Remote Sensing
    • /
    • v.24 no.5
    • /
    • pp.445-452
    • /
    • 2008
  • Preliminary results are reported on ship detection using coherence images computed from cross-correlating images of multi-look-processed dual-polarization data (HH and HV) of ENVISAT ASAR. The traditional techniques of ship detection by radars such as CFAR (Constant False Alarm Rate) rely on the amplitude data, and therefore the detection tends to become difficult when the amplitudes of ships images are at similar level as the mean amplitude of surrounding sea clutter. The proposed method utilizes the property that the multi-look images of ships are correlated with each other. Because the inter-look images of sea surface are covered by uncorrelated speckle, cross-correlation of multi-look images yields the different degrees of coherence between the images and water. In this paper, the polarimetric information of ships, land and intertidal zone are first compared based on the cross-correlation between HH and HV images, In the next step, we examine the technique when the dual-polarization data are split into two multi-look images, It was shown that the inter-look cross-correlation method could be applicable in the performance improvement of small ship detection and the land masking, It was also found that a simple combination of coherence images from each co-polarised (HH) inter-look and cross-polarised (HV) inter-look data can provide much higher target-detection possibilities.

Classification Analysis of the Physical Environment of Bicycle Road -Focused on Chang Won City, Kyung Nam Province, S. Korea- (자전거 도로의 물리적 환경에 대한 등급화 연구 -창원시 사례를 중심으로-)

  • Moon, Ho-Gyeong;Kim, Dong-Pil;Choi, Song-Hyun;Kwon, Jin-O
    • Korean Journal of Environment and Ecology
    • /
    • v.28 no.3
    • /
    • pp.365-373
    • /
    • 2014
  • This study is to analyze the physical environment and conduct spatial data for bicycle road system in changwon. Index for evaluation index was developed based on literatures. Then the level of importance and weight have been modified through experts review. Finally, index with eight categories such as greenness(40% over), bicycle road connectivity(1.8, 9.8%), road type bike(bicycle lane, 24.4%), pave type(asphalt 72.5%), illegal parking(none, 93.9%), bike road surface visibility(exist, 46.8%), vehicle speed limits(30km, under), vehicle traffic(500/hr under, 44.3%) have been applied to empirical investigation. Collected data has been hierarchically classification by ArcGIS Program. The Highest grades(score 31-35, level 1) occupied 35% of target destination. High level of greenness and load type has contributed to high score. In addition, average level of greenness of those destination was 35% and higher, which provide high degree of security and freshness for bicycle riding. Meanwhile, lowest level(level 5, which earned 15 point or less) occupied 24.5%. illegal parking, low level of greenness, and no surface sign caused low score.

A Temporal Trend of Dioxins Levels in Environmental Media

  • Park, Kyunghee;Daeil Kang;Junheon Youn;Lee, Choong;Sunghwan Jeon;Jingyun Na
    • Proceedings of the Korea Society of Environmental Toocicology Conference
    • /
    • 2003.05a
    • /
    • pp.148-148
    • /
    • 2003
  • This study is to investigate the environmental levels and trend of dioxins, which was the 3$\^$rd/ year of environmental monitoring research for endocrine disrupting chemicals since 1999. Total 282 samples were analyzed from 115 sites including 26 sites of airs, 43 sites of waters, 11 sites of sediments and 35 sites of soil, which were the same as those of investigated sites in 2000. Sampling period was from June 2001 to June 2002. Target chemicals were seventeen species of 2,3,7,8-chlorine-substituted PCDD and PCDF congeners and were analyzed by the standard methods, established by National Institute Environmental Research (NIER). The average concentration of dioxins in air decreased from 0.324 pg-TEQ/N㎥ in 2000 to 0.287 pg-TEQ/N㎥ in 2001, and those in water and soil were 0.073pg-TEQ/L and 1.703pg-TEQ/dry g, respectively, which was the less values detected in 2000. In sediment, however, the value was 0.086pg-TEQ/dry g, which was the increase from the value of the year 2000. The concentration range of dioxins in air for 26 sites in 17 regions detected were 0.013∼l.664pg-TEQ/N㎥, 4 sites from those were exceeded the Air Quality Standards of Dioxin in Japan (0.6 pg-TEQ/N㎥). The tolerable daily intake of dioxins was calculated at the highest level (1.664) in air, with referring the soil and food data from Japan, was calculated to be 2.85pg-TEQ/kg/day, which was below the level of 4 pg-TEQ/kg/day suggested in KFDA(Korea). While the average concentration of dioxins in 15 big cities was 0.190 pg-TEQ/N㎥, that in 8 medium/small cities constituting an industrial complex was 0.558 pg-TEQ/N㎥. In water, the concentration range detected were 0∼0.946pg-TEQ/L and the trend of the average concentrations shows an increase from those of 1999 but decreased from those of 2000, any sites however were not exceeded the Water Quality Standards of Dioxin in Japan (1 pg- TEQ/L). In soil. the detected range were 0∼43.333 pg-TEQ/dry g and the average concentration decreased, compared with the results of 2000. According to the monitoring results by land utilization, the detected range were 0∼43.333pg-TEQ/dry g in farmland, 0.017∼0.601 pg-TEQ/dry g in the industrial area, 0.005∼0.049pg-TEQ/dry g in the park and 0.008∼1.825 pg-TEQ/dry g in the rest. In sediment, the detected range increased from 0∼0.244 pg-TEQ/dry g to 0∼0.537 pg-TEQ/dry g, based on the results of 2000. For the proper control of dioxins, continuous monitoring needs to be performed and in addition, the dioxin inventory should be prepared for major sources through the dioxin emission survey. These results would provide sound and solid basis for proper decision making of dioxins management like establishment of environmental quality standards in Korea.

  • PDF

Design for Landfill Gas Application by Low Calorific Gas Turbine and Green House Optimization Technology (Low Calorific Gasturbine 매립지 적용 및 유리온실 운용기술 설계)

  • Hur, Kwang-Beom;Park, Jung-Keuk;Lee, Jung-Bin;Rhim, Sang-Gyu
    • 한국신재생에너지학회:학술대회논문집
    • /
    • 2010.06a
    • /
    • pp.244.1-244.1
    • /
    • 2010
  • Bio energy development by using Low Calorific Gas Turbine(LCGT) has been developed for New & Renewable energy source for next generation power system, low fuel and operating cost method by using the renewable energy source in landfill gas (LFG), Food Waste, water waste and Livestock biogas. Low calorific fuel purification by pretreatment system and carbon dioxide fixation by green house system are very important design target for evaluate optimum applications for bio energy. Main problems and accidents of Low Calorific Gas Turbine system was derived from bio fuel condition such as hydro sulfide concentration, siloxane level, moisture concentration and so on. Even if the quality of the bio fuel is not better than natural gas, LCGT system has the various fuel range and environmental friendly power system. The mechanical characterisitics of LCGT system is a high total efficiency (>70%), wide range of output power (30kW - 30MW class) and very clean emmission from power system (low NOx). Also, we can use co-generation system. A green house designed for four different carbon dioxide concentration from ambient air to 2000 ppm by utilizing the exhaust gas and hot water from LCGT system. We look forward to contribute the policy for Renewable Portfolio Standards(RPS) by using LCGT power system.

  • PDF