• Genomics & Informatics
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• v.15 no.3
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• pp.98-107
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• 2017

MicroRNAs (miRNAs) act as regulators of gene expression by binding to the 3' untranslated region (UTR) of target genes. They perform important biological functions in the various species. Among many miRNAs, miR-21-3p is known to serve vital functions in development and apoptosis in olive flounder. Using genomic and bioinformatic tools, evolutionary conservation of miR-21-3p was examined in various species, and expression pattern was analyzed in olive flounder. Conserved sequences (5'-CAGUCG-3') in numerous species were detected through the stem-loop structure of miR-21-3p. Thus, we analyzed target genes of miR-21-3p. Among them, 3' UTR region of PPIL2 gene indicated the highest binding affinity with miR-21-3p based on the minimum free energy value. The PPIL2 gene showed high expression levels in testis tissue of the olive flounder, whereas miR-21-3p showed rather ubiquitous expression patterns except in testis tissue, indicating that miR-21-3p seems to control the PPIL2 gene expression in a complementary repression manner in various tissues of olive flounder. Taken together, this current study contributes to infer the target gene candidates for the miR-21-3p using bioinformatics tools. Furthermore, our data offers important information on the relationship between miR-21-3p and target gene for further functional study.

• Korean Journal of Veterinary Research
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• v.36 no.1
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• pp.101-108
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• 1996

This study was desinged to investigate the effect of estrogen(Est) on the proliferating of progesterone(Prog) target cells. The spayed 13 rats(Wistar, approximately 300gm) were randomly alloted into 3 groups. One group was the control group and another Prog-treated group was injected with 1mg of Prog/rat/day for 2 consecutive days, and Estand Prog-treated group was injected intramuscularly with $17{\beta}$-estradiol $20{\mu}g/rat/day$ for 3 consecutive days and then with Prog for 2 days as above from 4th day. Rats were administrated intraperitoneally with bromodeoxyuridinc(Brdur,0.2mg/BW once) befero 2 hours of exanguination. In gross finding, the groups with more level of dimension and weight on the uterus were ordered as Est- and Prog-treated group, Prog-treated group and control group. The investigation by immunohistochemical methods using paraffin sections of the uteri was performed by using anti-Brdur antibody for labeling proliferating cells of Prog target cells. The groups with higher labeling index(LI) were ordered as Prog-treated grop, Est- and Prog- treated group and control group. The number of proliferating cells from Prog target cells in the rats were rather deceased by Prog injection following Est injection than prog injection only. The cell types with higher LI in the wall layers of all 3 groups were ordered as endometrial stromal cells, glandular epithelial cells, luminal epithelial cells, myometrial muscle cells and serosa methodelial cells, and the region with highest LI was functional zone of the endometrium and the region with lower LI was muscular layer and then those with lowest LI was serosa and also the considerable different LI from individual rat were observed.

• Radiation Oncology Journal
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• v.38 no.1
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• pp.18-25
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• 2020

Purpose: This study was aim to evaluate the patterns of failure according to radiotherapy (RT) target volume for cervical lymph nodes in metastases of unknown primary origin in head and neck region (HNMUO). Materials and Methods: Sixty-two patients with HNMUO between 1998 and 2016 were retrospectively reviewed. We analyzed the clinical outcomes and primary site failure depending on the radiation target volume. The target volume was classified according to whether the potential head and neck mucosal sites were included and whether the neck node was treated involved side only or bilaterally. Results: Potential mucosal site RT (mucosal RT) was done to 23 patients and 39 patients did not receive mucosal RT. Mucosal RT showed no significant effect on overall survival (OS) and locoregional recurrence (LRR). The location of primary site failure encountered during follow-up period was found to be unpredictable and 75% of patients with recurrence received successful salvage therapies. No significant differences in OS and LRR were found between patients treated to unilateral (n = 35) and bilateral neck irradiation (n = 21). Treatment of both necks resulted in significantly higher mucositis. Conclusions: We found no advantages in OS and LRR of patients with HNMUO when mucosal sites and bilateral neck node were included in the radiation target volume.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.9C
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• pp.863-870
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• 2009

Bilateral filter (BF) is a nonlinear filter for sharpness enhancement and noise removal. The BF performs the function by the two Gaussian filters, the domain filter and the range filter. To apply the BF to infrared (IR) small target detection, the standard deviation of the two Gaussian filters need to be changed adaptively between the background region and the target region. This paper presents a new BF with the adaptive standard deviation based on the analysis of the edge component of the local window, also having the variable filter size. This enables the BF to perform better and become more suitable in the field of small target detection Experimental results demonstrate that the proposed method is robust and efficient than the conventional methods.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.3
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• pp.53-61
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• 2012

This paper proposes a real-time distance measurement system of high temperature and high speed target using infrared stereo camera. We construct an infrared stereo camera system that measure the difference between target and background temperatures for automatic target measurement. First, the proposed method detects target region based on target motion and intensity variation of local region using difference between target and background temperatures. Second, stereo matching by left and right target information is used to estimate disparity about real-time distance of target. In the proposed method using infrared stereo camera system, we compare distances in three dimension trajectory measuring instrument and in infrared stereo camera measurement. In this experiment from three video data, the result shows an average 9.68% distance error rate. The proposed method is suitable for distance and position measurement of varied targets using infrared stereo system.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.6
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• pp.510-518
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• 2004

The PID trajectory tracking controller for robotic systems shows performance limitation imposed by inverse dynamics according to desired trajectory. Since the equilibrium point can not be defined for the control system involving performance limitation, we define newly the quasi-equilibrium region as an alternative for equilibrium point. This analysis result of performance limitation can guide us the auto-tuning method for PID controller. Also, the quasi-equilibrium region is used as the target performance of auto-tuning PID trajectory tracking controller. The auto-tuning law is derived from the direct adaptive control scheme, based on the extended disturbance input-to-state stability and the characteristics of performance limitation. Finally, experimental results show that the target performance can be achieved by the proposed automatic tuning method.

• Journal of Korea Multimedia Society
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• v.17 no.4
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• pp.458-465
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• 2014

In this paper, we propose a strategy to distribute the energy consumption over the network. The proposed strategy is based on geographic routing. We use a smart base station that maintains the residual energy and location information of sensor nodes and selects a head node and an anchor node using this information. A head node gathers and aggregates data from the sensor nodes in a target region that interests the user. An anchor node then transmits the data that was forwarded from the head node back to the smart base station. The smart base station extends network lifetime by selecting an optimal head node and an optimal anchor node. We simulate the proposed protocol and compare it with the LEACH protocol in terms of energy consumption, the number of dead nodes, and a distribution map of dead node locations.

• 한국정보디스플레이학회:학술대회논문집
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• 2002.08a
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• pp.872-875
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• 2002

This paper presents an efficient method of estimating the correlated color temperature of an input color image and of generating a converted color image that can approximate the new target color temperature. After extracting the potential reference white region for an uncalibrated color image and estimating its correlated color temperature, the color conversion method produces a new color image with a target color temperature. Speed improvement and memory reduction have been achieved by using a simple transfer method without involving the CIE XYZ conversion step.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05a
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• pp.660-665
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• 1998

The feasibility study on conceptual design methodology for accelerator-driven sodium-cooled sub-critical transmutation reactors has been conducted to optimize the design parameters from the scale laws and validates reactor performance with the integrated code system. A 1000 MWth sodium-cooled sub-critical transmutation reactor has been scale and verified through the methodology in this paper, which is referred to advanced Liquid Metal Reactor (ALMR). a Pb-Bi target material and a partitioned fuel are the liquid phases, and they are cooled by the circulation of secondary Pb-Bi coolant and by primary sodium coolant, respectively. Overall key design parameters are generated from the scale laws and they are improved and validated by the intergrated code system. Intergrated Code System (ICS) consist of LAHET, HMCNP, ORIGEN2, and COMMIX codes and some files. Through ICS the target region, the core region, and thermal-hydraulic related are analyzed once-through. Results of conceptual design are attached in this paper.

• Journal of The Korean Society of Agricultural Engineers
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• v.55 no.6
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• pp.87-99
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• 2013

For analysis of climate change effects on agriculture, precise agricultural meteorological data are needed to target period and site. In this study, agricultural meteorological data under new climate change scenario (RCP 8.5) are constructed from 2011 to 2099 in 111 agriculture major station suggested by Rural Development Administration (RDA). For verifying constructed data, comparison with field survey data in Suwon shows same trend in maximum temperature, minimum temperature, average temperature, and precipitation in 2011. Also comparison with normals of daily data in 2025, 2055, and 2085 shows reliability of constructed data. In analysis of constructed data, we can calculate sum of days over temperature and under temperature. Results effectively show the change of average temperature in each region and odd days of precipitation which means flood and dry days in target region.