• Title/Summary/Keyword: Tail Effect

Search Result 622, Processing Time 0.028 seconds

Bee Venom Therapy of Tail-docked Dog (단미 창상의 생봉독 요법)

  • 최석화;강성수
    • Journal of Veterinary Clinics
    • /
    • v.15 no.2
    • /
    • pp.247-250
    • /
    • 1998
  • This study was designed to examine therapeutic effect of honeybee venom on wound healing in tail-docked dog. Blood samples were taken of jugular vein and hematological values were analyzed in condition of pre,3- and 6-day after canine caudectomy. Apitherapy group was subcutaneously treated with an Italian honeybee(Apis mellifera ligustica). Antibiotic therapeutic group was intramuscularly iaiected with a standard dosage ol'penicluin ,G procaine(20,000 Units/kg of body weight). Changes of leucocyte, erynlrocytel hematocrit, platelet and fibrinogen were not significantly different between bee sting and penicillin injection during wound healing. No changes of wound healing in tine tests, groups were onseren. Whole honeybee venom has been shown to have a antiinflammatory effect in tail-docked dog. It may be concluded that honeybee venom is effective drug being useful far wound healing and disinfection without tissue trauma in dog.

  • PDF

Electrophysiologic Mechanism of Tail Flick Reflex in Rats (흰쥐 Tail Flick Reflex의 신경생리학적 기전)

  • Seoh, Sang-Ah;Kim, Jun
    • The Korean Journal of Physiology
    • /
    • v.23 no.1
    • /
    • pp.139-149
    • /
    • 1989
  • Although tail flick reflex (TFR) in rats has been used as a classic model of the nociceptive test to evaluate the action of analgesics, there have been few studies on the origin of the latent period of TFR. Present study was performed to elucidate the mechanism of increase in latency of TFR by morphine in anesthetized rats. Tail skin and dorsolateral tail nerve were stimulated electrically and EMG activities were recorded from abductor caudae dorsalis muscle participating in tail flick reflex. In the case of noxious radiant heat stimulation to tail, the tail flick tension was recorded before and after administration of morphine. Then changes in latency and conduction velocity of peripheral nerve were evaluated. The results obtained were as follows: 1) The latencies of TFR evoked by the electrical stimulation of tail skin and dorsolateral tail nerve were all within 40 ms and were elongated by several milliseconds from control after the administration of morphine. Peripheral conduction velocities of tail flick afferent nerve were within the range of 10-25 m/s. 2) The conduction velocity of peripheral nerve was significantly reduced after morphine administration, therefore the afferent time (utilization time+conduction time to spinal cord) was significantly increased. But the time for central delay and efferent time was not affected by morphine. 3) The conduction velocity under room temperature $(20-25^{\circ}C)$ was significantly reduced after morphine while that under vasodilation state $(40{\sim}42^{\circ}C)$ increased, 30 min and 45 min after morphine. The conduction velocity under vasodilation state without treatment of morphine increased continuously 4) The latency in tension response of TFR evoked by electrical stimulation was elongated by several milliseconds from control while the latency evoked by noxious radiant heat was elongated by several seconds compared with that of control. From the above results, it could be concluded that: 1) the increased latency of TFR evoked by electrical stimulation of the tail after morphine administration was due to the reducton in conduction velocity of peripheral nerve, which was the secondry effect of morphine on the peripheral vasomotion and 2) increased latency of TFR evoked by noxious radiant heat was also due to the same effect of morphine and the increase in cutaneous insulation to the noxious heat.

  • PDF

Comparison of the Amino-Acid Content in Pharmacopuncture Extracts Taken from a Scorpion's Body and from Its Tail

  • Lee, Jin-Ho;Shin, Joon-Shik;Chi, Eun-Hya;Lee, In-Hee
    • Journal of Pharmacopuncture
    • /
    • v.16 no.2
    • /
    • pp.33-40
    • /
    • 2013
  • Objective: This study was conducted to investigate the amino-acid compositions of pharmacopuncture extracts taken from the body and from the tail of Buthus martensii Karsch, which are frequently prescribed in Oriental medicine. Methods: Amino acids in hot water and 70% ethanol extracts taken from the scorpion's whole body and from its tail were screened by using high performance liquid chromatography (HPLC). The experiments were performed with linearity, precision and accuracy. Results: The results of the amino-acid-composition analysis showed that the Buthus martensii Karsch extracts contained various amino acids such as aspartic acid, histidine, alanine, tyrosine, and cystine. The amino-acid analysis showed that the hot water extract was more beneficial than the ethanol extract, except for histidine. The amino acids from the tail and the body of the scorpion were compared, and the concentration of aspartic acid in the extract from the scorpion's tail was two times that found in the extract from its body. The results of validation experiments were all satisfactory. Conclusion: Studies on the ingredients in extracts from a scorpion other than buthotoxin may demonstrate that the antiepileptic efficacy, anticancer activity, anti-thrombotic action and analgesic effect are enhanced. Using only the tail of the scorpion when pharmacopuncture is dispensed may be beneficial because the extracts from the tail of the scorpion have higher potency than those from the whole body.

A wing-tail interference for a tail-controlled missile (꼬리날개 조종 유도무기의 주날개-꼬리날개 간섭 현상)

  • Kim, Duk-Hyun;Lee, Dae-Yeon;Kang, Dong-gi;Lee, Hyoung Jin
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.45 no.10
    • /
    • pp.817-824
    • /
    • 2017
  • This paper presents the characteristics of wing-tail interference for a tail-controlled missile. The magnitude of wing-tail interference was calculated with wind tunnel test results and its effects on aerodynamic coefficients were investigated. The downwash angle of tail wing was calculated with experimental data and the effect of wing-tail interference was expressed as a ratio of angle of attack. Numerical simulations were made to examine flow characteristics of wing-tail interference and the vorticity contour of missile were compared with respect to angle of attack. Experimental and numerical analysis results show that the wing-tail interference has significant effects on static stability of tail-controlled missile.

Association Analysis between Five Microsatellite Loci and Litter Size in Small Tail Han Sheep

  • Chu, M.X.;Wang, J.Z.;Wang, A.G.;Li, N.;Fu, J.L.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.16 no.11
    • /
    • pp.1555-1559
    • /
    • 2003
  • The objective of the present study was to explore associations between five microsatellites linked to $Fec^B$ and $FecX^I$ genes and litter size in Small Tail Han sheep. The polymorphisms of five microsatellite loci, OarAE101, BM1329, BMS2508, TGLA54 and TGLA68 were detected in 244 ewes of Small Tail Han sheep. Analysis of association between three microsatellite loci (BMS2508, BM1329 and OarAE101) located in the 10 cM region covering the $Fec^B$ gene (Booroola gene) and litter size in Small Tail Han sheep indicated that BMS2508 had significant effect on litter size in the second parity (p<0.05), but no significant effect on litter size in the first parity (p>0.05), while the other two microsatellite loci had no significant effect on litter size in both the first and the second parity in Small Tail Han sheep (p>0.05). At microsatellite locus BMS2508, least squares means in the second parity of genotypes 101/111 and 99/109 were significantly higher than those of genotypes 99/99, 99/101, 99/111 and 99/115 (p<0.05); least squares mean in the second parity of genotype 101/111 was significantly higher than that of genotypes 109/111 and 111/111 (p<0.05). Results of this study also indicated that two microsatellite loci (TGLA54 and TGLA68) that confined the 28.7 cM region covering the $FecX^I$ gene (Inverdale gene) did not affect litter size in both the first and the second parity in Small Tail Han sheep significantly (p>0.05). The information found in the present study is very important for improving the reproductive performance in sheep breeds by marker assisted selection.

Analgesic Effect of DA-5018, a New Capsaicin Derivative, against Experimental Acute Pain (새로운 캅사이신 유도체 DA-5018의 급성통증 모델에서의 진통작용)

  • 손문호;배은주;김희기;신명수;김순희;김원배;양중의;박노상
    • Biomolecules & Therapeutics
    • /
    • v.5 no.1
    • /
    • pp.67-73
    • /
    • 1997
  • Analgesic effect of DA-5018, a new capsaicin derivative, was evaluated in various rat models of experimentally induced acute pain. DA-5018(0.2∼10.0 mg/kg, p.o.) prevented the writhing syndromes induced by acetic acid or phenol-p-benzoquinone(PBQ). It increased the pain threshold of inflamed paw when tested by the Randall-Selitto method at the dose of 2.0∼20.0 mg/kg by oral administration. And also it showed antinociceptive activities in tail-pinch(1.0∼20.0 mg/kg, p.o.) and tail-flick test(5.0∼50.0 mg/kg, p.o.). the potency and efficacy of DA-5018 were comparable to morphine · HCI in all the models mentioned above. Acetaminophen exhibited the inhibition of acetic acid-induced writhing syndromes and also analgesic activity in Randall-Selitto test, but it showed the limited efficacy in tail-pinch and tail-flick test. These results mean that DA-5018 has a broader analgesic activity profile than acetaminophen. And we found out that the analgesic activity of DA-5018 was 100 times more potent when administered centrally than administered orally in tail-flick test. These results suggest that DA-5018 has an orally active analgesic activity, and central nervous system may be involved in the action of DA-5018.

  • PDF

Field test and numerical study of the effect of shield tail-grouting parameters on surface settlement

  • Shao, Xiaokang;Yang, Zhiyong;Jiang, Yusheng;Yang, Xing;Qi, Weiqiang
    • Geomechanics and Engineering
    • /
    • v.29 no.5
    • /
    • pp.509-522
    • /
    • 2022
  • Tail-grouting is an effective measure in shield engineering for filling the gap at the shield tail to reduce ground deformation. However, the gap-filling ratio affects the value of the gap parameters, leading to different surface settlements. It is impossible to adjust the fill ratio indiscriminately to study its effect, because the allowable adjustment range of the grouting quantity is limited to ensure construction site safety. In this study, taking the shield tunnel section between Chaoyanggang Station and Shilihe Station of Beijing Metro Line 17 as an example, the correlation between the tail-grouting parameter and the surface settlement is investigated and the optimal grouting quantity is evaluated. This site is suitable for conducting field tests to reduce the tail-grouting quantity of shield tunneling over a large range. In addition, the shield tunneling under different grouting parameters was simulated. Furthermore, we analyzed the evolution law of the surface settlement under different grouting parameters and obtained the difference in the settlement parameters for each construction stage. The results obtained indicate that the characteristics of the grout affect the development of the surface settlement. Therefore, reducing the setting time or increasing the initial strength of the grout could effectively suppress the development of surface subsidence. As the fill ratio decreases, the loose zone of the soil above the tunnel expands, and the soil deformation is easily transmitted to the surface. Meanwhile, owing to insufficient grout support, the lateral pressure on the tunnel segments is significantly reduced, and the segment moves considerably after being removed from the shield tail.

Fundamental Study on Pinching Mechanism in Hot Strip Mill (사상 압연 공정에서 꼬임 발생 메커니즘에 대한 기초 연구)

  • 신기현;권순오;이창우;안영세;정동택;홍완기
    • Proceedings of the Korean Society of Precision Engineering Conference
    • /
    • 2003.06a
    • /
    • pp.1091-1096
    • /
    • 2003
  • It is very important to find out causes of strip pinching for the high quality of products and for the stable operation of hot roiling system. We have examined the strip pinching from three points of view to find out the causes of strip pinching in hot rolling system: strip shape, rolling operation conditions, and behavior of strip. Wedge, off center, and difference of rolling force through CMD are found to possibly provide major initial causes of strip pinching. Generally strip pinching occurred in the tail of strip. Thus, computer simulations by using a FEM code were also carried out to find out the initial mechanism of strip pinching depending upon the force and geometric boundary conditions at the time of strip tail rolling. The strong compression force effect due to the sudden release of strip tail from the work roll and non-uniform strip tail shape (ex. Tongue tail) across the CMD were found to provide possible major causes of strip pinching.

  • PDF

Liquidity and Skewness Risk in Stock Market: Does Measurement of Liquidity Matter?

  • CHEUATHONGHUA, Massaporn;WATTANATORN, Woraphon;NATHAPHAN, Sarayut
    • Journal of Distribution Science
    • /
    • v.20 no.12
    • /
    • pp.81-87
    • /
    • 2022
  • Purpose: This study aims to explore the relationship between stock liquidity and skewness risk-tail risk (stock price crash risk) in an emerging market, in which problems on liquidity are more severe than in developed markets. Research design, data, and methodology: Based on the Thai market stock exchange over the period of 2000 to 2019, our sample include 13,462 firm-period observations. We employ a panel regression models regarding to five liquidity measures. These five liquidity measures cover three dimensions of liquidity namely the volume-based, price-based, and transaction cost-based measures for the liquidity-tail risk relationship. Results: We find a positively significant relationship between stock liquidity and tail risk in all cases. The finding here shows that the higher the stock liquidity, the larger the tail risk is. Conclusion: As the prior studies show inconclusive effect of stock liquidity on stock price crash risk, we demonstrate that mixed results found in prior studies are probably driven from the type of liquidity measure. The stock liquidity-tail risk association is present in the Stock Exchange of Thailand. The results remain the same regardless of the definition of tail risk and liquidity factors. An endogeneity issue is addressed by employing the two-stage least squares regression.

Tone in Text and the Effect on Trust and Choice Confidence in Online Fashion Shopping

  • Lee, Eun-Jung;Kim, Hahn
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.39 no.5
    • /
    • pp.703-713
    • /
    • 2015
  • Consumers' psychological demands for e-tail shopping have increased as websites have become one of the most dominant retail outlets for various fashion products. The lack of realistic social stimuli in virtual contexts (websites) has been a major limitation for many online shoppers. Prior research has focused on the viable role of technology to improve positive social factors in e-tailing; however, this study tests the role of tone in text in fashion e-tail sites on consumers' trust and choice confidence. We conducted a self-administered online survey with 309 individuals from the U.S.. The results indicated positive effects of casual tone in text-based content of a fashion e-tail site on trust and confidence. Trust also has a significant positive effect on confidence. Both trust and confidence improved purchase intention. Given the high price of employing an avatar or simulated salesperson online, using tone in text to increase positive social effect on shoppers can be a positive alternative when managers plan e-tail strategies contributing to consumers' positive shopping experience online. Discussions and study limitations are provided.