• 제목/요약/키워드: TVR

검색결과 66건 처리시간 0.024초

급성심근경색증 환자의 일차적 관동맥 스텐트 삽입술 시 삽입된 Sirolimus-eluting stent 와 Paclitaxel-eluting stent의 임상적 안정성 및 유용성 평가 (The evaluation for Clinical usefulness and Safety of Sirolimus-eluting stent and Paclitaxel-Eluting Stents In Patients With Acute Myocardial Infarction)

  • 민계식;한만석
    • 한국방사선학회논문지
    • /
    • 제6권1호
    • /
    • pp.5-10
    • /
    • 2012
  • AMI로 SES 혹은 PES 시술을 시행받은 모든 환자에서 4년 이상의 임상추적 기간이 지난 환자를 대상으로 데이터를 분석하여 두 스텐트의 안전성과 유용성을 비교해 보고자 하였다. 2004년 1월 1일부터 2006년 8월 31일까지 본원에서 ST분절 상승 혹은 ST 분절 비상승 급성심근경색증 (STEMI or NSTEMI)로 진단되어 입원 기간 중 관동맥중재술을 시행받은 환자 중 SES 혹은 PES 삽입술이 시행된 환자를 대상으로 후향적 분석을 시행하였다. 그리고 사망, 심장사. 심근경색증, 표적 혈관재관류술, 스텐트 혈전증 발생에 대해 분석하였다. 연구 기간 동안 총 668명의 급성심근경색증 환자가 중 522명만 연구 대상에 포함 사망 ($18.3{\pm}3.0%$ vs. $14.6{\pm}2.2%$, p=0.26), 심장사($11.2{\pm}2.6%$ vs. $6.8{\pm}1.52%$, p=0.39), 심근경색증 ($6.4{\pm}1.8%$ vs. $3.3{\pm}1.1%$, p=0.31), and 스텐트 혈전증 ($5.4{\pm}1.7%$ vs. $3.2{\pm}1.1%$, p=0.53) 표적 혈관재관류술(TVR) ($10.0{\pm}3.0%$ vs. $4.0{\pm}1.2%$, p=0.008) and 심혈관계 임상사건(MACE) ($29.4{\pm}3.5%$ vs. $19.4{\pm}2.5%$, p=0.003) 급성심근경색증의 초기 치료에 약물방출스텐트인 SES와 PES의 4년 장기 임상 성적을 조사한 본 연구를 통해 전체환자를 대상으로 분석하였을 때 두 스텐트의 장기 사망률, 심장사. 심근경색증, 표적 혈관재관류술, 스텐트 혈전증의 발생은 차이가 없었으나 TVR 및 MACE의 발생은 PES 삽입 환자가 SES삽입 환자보다 유의하게 높았다.

어종식별을 위한 광대역 초음파 변환기의 설계 ( III ) - 이중음향정합층을 이용한 초음파 변환기의 대역폭 확장 - (The Design of Broadband Ultrasonic Transducers for Fish Species Identification - Bandwidth Enhancement of a Ultrasonic Transducer Using Double Acoustic Matching Layers-)

  • 이대재
    • 수산해양기술연구
    • /
    • 제34권1호
    • /
    • pp.85-95
    • /
    • 1998
  • 어종의 식별을 위한 수중음향학적 정보를 수집하는 데 사용하기 위한 광대역 초음파 변환기를 개발할 목적으로 저주파용 Tonpilz형 초음파 변환기를 설계, 제작하고, 이 변환기의 음향 방사면에 $Al_2O_3$와 epoxy 수지를 서로 혼합하여 생성한 복합재료층과 폴리우레탄 수지로서 제작한 음향 정합층을 각각 직렬 접착시킨 복합구조 초음파 변환기의 광대역 주파수 특성에 대하여 분석, 고찰한 결과를 요약하면 다음과 같다. 1) Tonpilz형 transducer (head mass : 알류미늄 / 두께 22.0 mm, tail mass : 황동 / 두께 15.0 mm )의 음향 방사면에 두께 7.0 mm의 $Al_2O_3$와 epoxy 수지로서 생성한 복합재료층의 두께 18.0 mm의 폴리우레탄 수지로서 제작한 정합층을 직열접착한 복합 구조 초음파 변환기의 - 3 dB점에 대한 하한 및 상한 주파수 범위는 35.0~42.3 kHz (${\Delta}f=7.3 kHz)$이었고, 이 주파수 구간에 있어서의 송파전압감도의 최대치는 135.7 dB re $1\;{\mu}Pa/V$ 이었다. 2) Tonpilz형 transducer (head mass : 알류미늄 / 두께 23.0 mm, tail mass : 황동 / 두께 15.0 mm )의 음향 방사면에 두께 11.0 mm의 $Al_2O_3$와 epoxy 수지로서 제작한 복합재료층과 두께 15.8.0 mm의 폴리우레탄 수지로서 제작한 정합층을 직열접착한 복합 구조 초음파 변환기의 - 3 dB점에 대한 하한 및 상한 주파수 범위는 35.5~41.73 kHz (${\Delta}f=6.2 kHz)$이었고, 이 주파수 구간에 있어서의 송파전압감도의 최대치는 136.3 dB re $1\;{\mu}Pa/V$ 이었다. 3) 본 연구에서 시작한 복합구조 초음파 변환기에 chirp 신호(펄스 폭 4 ms, 중심주파수 40 kHz, 대역폭 40 kHz)를 인가하고, 수중방사음역에 있어서의 시간응답특성을 조사한 결과, 그 응답특성은 송신전압감도의 주파수특성과 매우 잘 일치하는 경향을 나타내었다. 이상의 결과로부터 본 연구에서 설계, 제작한 이중정합층을 갖는 복합구조 초음파 변환기는 단순구조의 Tonpilz형 초음파 변환기와 비교하여 비록 송파전압감도에 있어서는 약 5 dB 정도의 음향출력의 손실이 불가피하지만, 그 대신 주파수 대역폭을 약 5 재 정도 확대시킬 수 있는 장점이 있기 때문에 이 넓은 주파수 대역을 효과적으로 활용하면 어종식별을 위한 음향산란신호를 정량적으로 수집 및 평가하는 것이 가능하다고 판단된다.

  • PDF

심장조직판막치환: 7 년간의 술후 장기성 (Cardiac valve replacement: a 7-year long-term evaluation)

  • 이상호;성상현;서경필
    • Journal of Chest Surgery
    • /
    • 제16권4호
    • /
    • pp.602-614
    • /
    • 1983
  • Six hundred fourteen consecutive cases of bioprosthetic cardiac valve replacement performed during the period from March 1976 through December 1982 were reviewed. A total of 748 tissue valves [534 Ionescu-Shiley valves, 144 Hancock valves, 46 Angell-Shiley, and 24 Carpentier-Edwards] were implanted in 610 patients. Of these, 477 had single valve replacements [403 mitral, 60 aortic, and 14 tricuspid] including three REDO MVR and one REDO AVR. The remaining 129 had double valve replacements [95 AVR and MVR and 34 MVR and TVR] and 8 had triple valve replacement.592 cases were evaluated. Overall early mortality rate [within 30 days of operation] was 7.1% [6.2% in single valve replacement, 10.2% in double valve replacement, and 16.7% in triple valve replacement]. Leading causes of mortality were low cardiac output or myocardial failure and ventricular arrhythmias. The follow-up period was from one month to 7 years with a cumulative follow-up of 906.6 patient-years [mean 1.53 years]. The late mortality was 1.6%, 3.9%, 0%, 2.6%, 6.6% and 2.0% per patient-year for MVR, AVR, TVR or triple valve replacement, AVR+MVR, MVR+TVR and total, respectively. Actuarial analysis of late results including early mortalities indicates an expected survival rate of 87.6+1.8% at 3 years and 85.92.4% at 7 years for all cases. We also analyzed actuarial survival rate between groups of each valve replacement [AVR, TVR, Double valve, and Triple valve] and the tissue valve groups in MVR. We experienced 7 cases [0.77% per patient-year] of confirmed endocarditis, two of which were fatal. Valve failure-free rates calculated according to the confirmed cases were 97.5% at 4 years, 87.5% at 7 years, and 88.3% at 6 years for Ionescu-Shiley, Hancock and Angell-Shiley valves, respectively. The occurrence rate of thromboembolism was 2.0% per patient-year in total cases, although almost all the patients were given anticoagulant therapy for one year. The occurring rate in MVR was 1.5% and 2.7% per patient-year for Ionescu-Shiley and Hancock valve groups, respectively. The difference in actuarial rate free from thromboemboli between Ionescu-Shiley and Hancock groups was statistically significant [P value less than 0.001]. Thromboembolic events beyond the period of anticoagulation therapy mainly occurred in patients with atrial fibrillation. The actuarial thromboemboli free survival was 95.71.4% at 3 years and 80.17.3% at 7 years. The incidence of hemorrhagic complications was 1.2% per patient-year [fatality 0.55% per patient-year] for anticoagulated patients. Although our clinical data favorably compares with results from other reports, our results suggest that anticoagulant therapy be given on a short-term basis or not at all to hemodynamically stable patients. Long-term therapy with antiplatelet drugs is probably inevitable with patients who have thromboembolic risk factors [such as atrial fibrillation].

  • PDF

Taper형 초음파 진동자의 대역폭 개선에 관한 연구 (A Astudy on Bandwidth Enhancement of a Ultrasonic Transducer with a Taper)

  • 정봉규
    • 수산해양기술연구
    • /
    • 제35권3호
    • /
    • pp.312-322
    • /
    • 1999
  • A ultrasonic transduce with a single acoustic matching layer has been designed as an attempt to increase the bandwidth of underwater transducer. The wideband resonance condition was accomplished by attaching a single matching layer on the front face of a ceramic resonator composed of a piezoelectric bar, a taper part and a head part. A modified Mason's model was used for the performance analysis and the design of transducers, and the constructed transducers were tested experimentally and numerically by changing the impedance and thickness of the matching layer in the water tank.The obtained results are summarized as follows:1. Measured resonant and antiresonant frequencies of the piezoelectric transducer with no matching layer in air were 24.7 kHz and 25.6 kHz, respectively. 2. Two resonant frequencies of the piezoelectric transducer with a single matching layer were 21.7 kHx and 26.9 kHz, respectively, in air and 21.4 kHz and 22.7 kHz, respectively, with a water load.3. Two distinct resonance peaks in the transmitting voltage response(TVR) of the developed transducer were observed at 22.0 kHz and 25.8 kHz, respectively, with center frequency of 24.0 kHz. The values of TVR at these frequencies were 130.1 dB re $1 \muPa$/V at 22.0 kHz and 128.5 dB re $1 \muPa$/V at 25.8 kHz, respectively.Reasonable agreement between the experimental results and the numerical values was achieved.

  • PDF

1-3형 압전복합체를 이용한 광대역 수중 음향 트랜스듀서 개발 (Development of Underwater Wide-band Acoustic Transducer Using the 1-3 Piezoelectric Composite)

  • 이경우;소형종;임실묵;김원호;김대연
    • 한국소음진동공학회논문집
    • /
    • 제18권4호
    • /
    • pp.424-431
    • /
    • 2008
  • Recently, it is required that acoustic transducers for underwater detection and communication sensor have wide bandwidth and low operating frequency. In this research, the new acoustic transducer is proposed. This transducer is tonpilz type, and made of 1-3 piezoelectric composites as a driving parts. The developed transducer is evaluated the TVR(transmission voltage response) and RVS(receiving voltage sensitivity) characteristics around $4{\sim}14\;kHz$ frequency range and is compared to conventional tonpilz transducer made of solid piezoelectric ceramics as a driving parts. The resonance frequency of the developed transducer is decreased by 30% and the -3 dB bandwidth is increased by 90%, compared to conventional transducer with same dimensions. The value of TVR is decreased by 9 dB and The value of RVS is the same at resonance frequency.

심내막상 결손증에 대한 임상고 (Clinical study of endocardial cushion defect: 37 cases report)

  • 조재일;서경필
    • Journal of Chest Surgery
    • /
    • 제17권4호
    • /
    • pp.657-665
    • /
    • 1984
  • Thirty-seven patients had undergone repair of a endocardial cushion defect between 1977 and Aug. 1983 in Seoul National University Hospital. Twenty eight had a partial defect, one intermediate defect and eight complete endocardial cushion defect. Tricuspid cleft was found in 4 cases and mitral cleft was in all p-ECD. Seven patients were of type C anatomy in c-ECD. Four patients had associated major anomalies, including three TOF in c-ECD, one coarctation in p- ECD. In p-ECD patients, the septal defect was closed with patch in all cases and the atrioventricular valvular insufficiency was corrected with MVR in 4 cases, TVR in 1 case and simple interrupted sutures in remainders. In c-ECD patients the septal defect was closed with single patch except one case. The atrioventricular valve was repaired with simple interrupted sutures except one MVR and TVR case. The operative mortality was 14.2% in p-ECD, 44.4% in c-ECD, but recent 3 years [1980-1983] mortality was 8.7% in p-ECD, 20% in c-ECD. More than grade III systolic regurgitant murmur was oted postoperatively in 4 cases of c-ECD and 3 cases of p-ECD. The operative risk factors were preoperative NYHA classification, cyanosis, Rp/Rs, systolic pressure of main pulmonary artery and the degree of regurgitation of atrioventricular valves. The causes of death were low cardiac output syndromes, pulmonary complications and arrhythmias.

  • PDF

증기 이젝터 위치에 따른 다중효용증발시스템의 설계 및 성능분석 (Design and Evaluation of Multiple Effect Evaporator Systems According to the Steam Ejector Position)

  • 김득원;최상민
    • 설비공학논문집
    • /
    • 제28권11호
    • /
    • pp.434-443
    • /
    • 2016
  • The evaporation of water from an aqueous solution is widely used in the food, desalination, pulp, and chemical industries. Usually, a large amount of energy is consumed in the evaporation process to boil off water due to atmospheric pressure. As a way of improving the energy efficiency of the evaporation process, the combination of multiple effect evaporation and thermal vapor recompression has been proposed and has become a successful technique. In this study, 4 multiple-effect falling film type evaporators for sugar solution are designed and the energy efficiency of the system is analyzed in response to the selection of the steam ejector position. Energy efficiency is increased and vapor is more compressed in the steam ejector as the Thermal Vapor Recompression (TVR) is arranged in the rear part of the evaporator system. A simplified 0-dimensional evaporator model is developed using non-linear equations derived from mass balances, energy balances, and heat transfer equations. Steam economy is calculated to compare the evaporation performance of the 4 proposed evaporators. The entrainment ratio, compression ratio, and expansion ratio are computed to check the ejector performance.

Tonpilz 트랜스듀서의 성능에 미치는 압전소재의 영향 (Effects of piezoelectric material on the performance of Tonpilz transducer using finite element method)

  • 서진원;최균;이호용
    • 한국결정성장학회지
    • /
    • 제26권4호
    • /
    • pp.139-144
    • /
    • 2016
  • Tonpilz 트랜스듀서의 거동에 미치는 압전 소재의 형상과 크기의 효과에 대하여 유한요소법을 통한 컴퓨터 모사를 통하여 연구하였다. 도넛 형태의 압전체의 직경과 높이 그리고 쌓아올린 stack의 수를 변수로 고려하였고 최종적으로 소재 자체를 특성이 뛰어난 단결정 소재로 변환하였을 때 그 특성인 출력과 TVR 대역폭이 어떻게 변하는지를 모사하였다. 그 결과, 리랙서 단결정을 활용함으로써 같은 구조에서 출력을 10배 정도 향상시킬 수 있음을 확인하였다.

광대역 수중 음향 압전 진동체의 등가회로 모델링 (Equivalent Circuit Modeling of Wideband Underwater Acoustic Piezoelectric Vibrator)

  • 조치영;김원호;윤형규
    • 소음진동
    • /
    • 제6권5호
    • /
    • pp.645-652
    • /
    • 1996
  • In this paper an identification method is presented to obtain the equivalent electric circuit model of a wideband underwater acoustic piezoelectric vibrator. Unknown parameters involved in the equivalent circuit are indentified using the measured electrical admittances in air. The proposed method is applied to an example transducer. The validity of equivalent circuit model is demonstrated by the comparison between the experimental measurements and analytical calculations of TVR(transmitting voltage response) in water.

  • PDF

에너지절감을 위한 폐열회수용 열압축기에 대한 고찰 (A study for steam energy savings by the thermal vapor recompressor)

  • 이재근
    • 기술사
    • /
    • 제41권3호
    • /
    • pp.50-54
    • /
    • 2008
  • Recently most companies require various type of energy sources, in order to be more energy efficient in their plant due to the increasing current oil price. So, the multi-national companies are shaping ideas how to reduce energy costs and use substitute energy. The purpose of this study Is to attempt to save energy by making more valuable high pressure steam through TVR(Thermal Vapor Recompressor) from the surplus low pressure steam of HRB(Heat Recovery Boiler) in sulfuric acid plant.

  • PDF