• 한국직업건강간호학회지
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• 제20권3호
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• pp.231-239
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• 2011

Purpose: The purpose of this study was to identify the differences and relationships among knowledge, attitudes, skill, self-efficacy (SE), and Job satisfaction (JS) of healthcare managers (HMs) participated in the 4 kinds of continuing education. Methods: The subjects were 152 HMs. Data were analyzed by Mann-Whitney U test, Kruskal-Wallis H test, and partial correlation. Results: There were significant differences in knowledge according to the amount of healthcare management experience (HME) and the training program level (TPL); in the attitudes according to gender, age, and the TPL; in the skill according to the amount of HME and the TPL; and in SE according to gender and the TPL. There was no significant difference in JS according to general characteristics. There were significant positive correlations among knowledge, attitudes, skill, SE, and JS. Conclusion: The TPL was identified as a significant common variable that affects all variables apart from JS. According to these results, knowledge, attitudes, skill, and SE are considered as intrapersonal constructs, whereas JS is considered as an organizational construct. Therefore, in order to improve the quality of healthcare management, organizational strategy to enhance job satisfaction of HMs are recommended.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2004년도 춘계학술발표대회
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• pp.457-460
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• 2004

현재 무한경쟁의 시장환경 속에서 기업자체만으로 어려움을 감내하기란 많은 문제를 갖고있다. 그래서 기업은 물류활동을 전문적으로 담당하는 훌륭한 파트너를 통하여 이 문제를 해결하고 있으며 이전의 수직적 업무관행을 넘어선 동반자적인 파트너로써의 제 3 자 물류(TPL : Third Part Logistics : 이후 TPL로 표기함)를 활용하고 있다. 파트너관계는 이전에도 중요한 기업 전략이었으나 인터넷과 수많은 정보기술의 보급을 통한 전자상거래의 도래로 기업은 신속하고 정확하게 시장과 고객의 요구와 니즈를 만족시킬 수 있는 선도기술개발과 서비스제공능력이 기업의 핵심역량으로써 중요하게 되었다. 그래서 이러한 역량과 유연성을 갖춘 파트너와의 전략적관계형성과 관리를 할 수 있는 체계적인 파트너관계업무프로세스가 필요하게 되었다. 따라서 본 논문에서는 TPL 기업에서 유연한 공급사슬파트너관계구축과 관리를 가능하게 하고 고객요구를 대처할 수 있을 뿐만 아니라 미래의 고객요구를 예측가능 할 수 있는 방안으로 e-PRM 모델을 제시하고자 한다.

• 한국디지털정책학회:학술대회논문집
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• 한국디지털정책학회 2006년도 추계학술대회
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• pp.285-298
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• 2006

The third party logistics(3PL) is given a definition as logistics activaties providing a comprehensive logistics services, all or partly outsourced by the customer on longer term contract basis, ranging from making logistics strategies to implementing information technology services. The growth of the Third Party Logistics (TPL) business has caused many firms from different industries to enter the field. In this study, it is presented to describe a defintion and development precess of the third party logistics and shown to present strategic issues comparing to third party in foreign and domestic area. and apply some issues of importance when managing the continued TPL business strategy in domestic area.

• 통상정보연구
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• 제9권1호
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• pp.213-233
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• 2007

The third party logistics(3PL) is given a definition as logistics activities providing a comprehensive logistics services, all or partly outsourced by the customer on long-term contract basis, ranging from making logistics strategies to implement information technology services. The growth of the Third Party Logistics (TPL) business has been caused many firms to penetrate into the field from different industries. In this study, it is presented to describe a definition and development process of the third party logistics and shown to present strategic issues comparing to third party logistics in foreign and domestic area. and apply to some issues of importance when managing the continued TPL business strategy in domestic area.

• 한국식품영양과학회지
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• 제41권11호
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• pp.1626-1631
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• 2012

김치 및 젓갈류에서 probiotics의 기능을 갖는 유산균을 분리하여 발효두부 제조용 starter로 선별하여 김치양념을 이용한 발효두부 제조 가능성을 검토하였다. 분리한 60균주의 병원성균에 대한 항균활성과 인공위액 및 담즙산에 대한 내성이 우수한 균주 KL-6를 선발하였다. 최종 선발된 KL-6의 배양액의 DPPH free radical 소거능을 측정한 결과 성장에 따라 항산화 활성이 증가하였고, 16S rRNA 염기서열 분석에 의해 동정한 결과 P. acidilactici KL-6(100%)로 확인되었다. 김치 양념과 혼합한 두부(Control)와 선발유산균을 starter로 접종(2%, v/v)하여 김치 양념과 혼합한 두부(TL) 그리고 starter를 접종하여 $37^{\circ}C$에서 24시간 동안 전 발효시킨 김치 양념과 혼합한 두부(TPL)의 발효 특성을 비교하였다. pH는 발효 1주 경과 후 모든 처리구에서 감소하였고, 발효 14주에 각 처리구별 pH는 3.96(control), 3.97(TL), 4.03(TPL)이었다. 유산발효두부의 총균수는 발효 2주까지 모든 처리구에서 증가하였으며, 이후 감소하는 경향을 나타내었다. 유산균수의 경우 TL 및 TPL구는 발효 1주째, 대조구는 발효 2주째 $10^6$ CFU/g에 도달하였으며, 발효가 진행됨에 따라 각 처리구 공히 감소하여 발효 14주째 $10^3$ CFU/g을 나타내었다. 대장균군수의 경우 대조구는 발효 1주일째까지 관찰되었으나, TL및 TPL구는 발효 1주째부터 관찰되지 않았다. 기호성은 TL구와 TPL구가 맛, 향, 조직감, 종합적 기호도에서 대조구보다 높았으며, TPL구가 가장 우수하였다.

• 한국미생물·생명공학회지
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• 제34권1호
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• pp.58-62
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• 2006

티로신 및 방향족 아미노산 유도체의 생물학적 합성에 이용되는 유용 효소인 tyrosine phenol-lyase(TPL) 활성을 평판배지에서 정량적으로 감지할 수 있는 기술을 개발하였다. 불투명 평판배지(turbid plate)의 제조과정은 먼저, 2 N염산과 DMSO로 조성된 공용매에 난용성 티로신을 400 mM 농도로 녹여서 배지에 가하고, 온도를 조절하여 니들형 티로신을 형성하도록 결정화를 유도하는 것이었다. 니들형 티로신은 일반적인 컬럼형에 비하여 약 $5{\sim}6$배 낮은 농도인 3.6g/L에서도 불투명 평판배지를 제조할 수 있었으며, 효소활성에 의하여 쉽게 분해되고, TPL활성의 고감도 고속탐색기술 개발에 적합하였다. 이 불투명 평판배지에 변이유발PCR법으로 제조한 TPL 라이브러리를 도말하고, 단일 콜로니 주변에서 형성되는 투명환의 크기와 실측한 TPL활성을 비교한 결과 직접적인 비례관계가 있음을 확인하였다. 따라서 난용성 물질의 미세입자를 평판배지에서 직접 발생시킨 후, 효소활성에 의한 투명환의 형성을 정량 관찰하는 본 연구의 방법은 신규 고활성 TPL의 분리 및 방향성 분자진화 등을 위한 고속탐색기술에 유용하게 사용될 수 있다.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권12호
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• pp.674-680
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• 2018

Background and Objectives The representative mucin genes in the human airway are MUC5AC and MUC5B, which are regulated by several inflammatory and anti-inflammatory substances. Triptolide (TPL), udenafil, betulinic acid, changkil saponin, and glucosteroid are some of the many anti-inflammatory substances that exist. TPL is a diterpenoid compound from the thunder god vine, which is used in traditional Chinese medicine for treatment of immune inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus, nephritis and asthma. However, the effects of TPL on mucin expression of human airway epithelial cells have yet to be reported. Hence, this study investigated the effect of TPL on lipopolysaccharide (LPS)-induced MUC5AC and MUC5B expression in human airway epithelial cells. Subjects and Method The NCI-H292 cells and the primary cultures of human nasal epithelial cells were used to investigate the effects of TPL on LPS-induced MUC5AC and MUC5B expression using real-time polymerase chain reaction, enzyme immunoassay, and Western blot. Results TPL significantly decreased the LPS-induced MUC5AC and MUC5B mRNA expression and protein production. TPL also significantly decreased the nuclear factor-kappa B (NF-kB) phosphorylation. Conclusion These results suggest that TPL down regulates MUC5AC and MUC5B expression via inhibition of NF-kB activation in human airway epithelial cells. This study may provide important information about the biological role of triptolide on mucus-secretion in airway inflammatory diseases and the development of novel therapeutic agents for controlling such diseases.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.144.1-144
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• 2003

Attenuated viruses can protect their hosts against challenge to their related viruses. Increasing evidence shows that mutations of the tobamoviral 126/183 kDa protein play a major role in the viral attenuation and contribute to the cross protection mechanism. In this study, four mutants of Pepper mild mottle virus (PMMoV) have been constructed by mutagenesis; two mutants, pTPpoly348 and pTPpoly762, were substituted in the middle of replicase gene, and the others, pTPL3D:: $\Delta$6207 and pTPL3D:: $\Delta$6219, were deletion mutants made by deleting some parts of pseudoknot structures of the 3' noncoding region (NCR) of the virus. Progeny viruses generated from the four mutants were infectious on N. benthamiana plants with symptomless or mild mosaic symptom. Replication efficiency and viral product accumulations of four mutants were assessed by Northern and Western blot analyses on BY-2 protoplast cells. Accumulation of CP for the pTPL3D:: $\Delta$6207 and pTPL3D:: $\Delta$6219 were lower than that of other mutants and wild type virus. These data suggest that the 3'-NCR mutations contribute to the viral gene expression in host tissues, while mutants of replicase gene rather govern the symptom expression.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권4호
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• pp.1854-1868
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• 2018

A wireless body-sensor network (WBSN) refers to a network-configured environment in which sensors are placed on both the inside and outside of the human body. The sensors are much smaller and the energy is more constrained when compared to traditional wireless sensor network (WSN) environments. The critical nature of the energy-constraint issue in WBSN environments has led to numerous studies on the reduction of energy consumption of WBSN sensors. The transmission-power-control (TPC) technique adjusts the transmission-power level (TPL) of sensors in the WBSN and reduces the energy consumption that occurs during communications. To elaborate, when transmission sensors and reception sensors are placed in various parts of the human body, the transmission sensors regularly send sensor data to the reception sensors. As the reception sensors receive data from the transmission sensors, real-time measurements of the received signal-strength indication (RSSI), which is the value that indicates the channel status, are taken to determine the TPL that suits the current-channel status. This TPL information is then sent back to the transmission sensors. The transmission sensors adjust their current TPL based on the TPL that they receive from the reception sensors. The initial TPC algorithm made linear or binary adjustments using only the information of the current-channel status. However, because various data in the WBSN environment can be utilized to create a more efficient TPC algorithm, many different types of TPC algorithms that combine human movements or fuse TPC with other algorithms have emerged. This paper defines and discusses the design and development process of an efficient TPC algorithm for WBSNs. We will describe the WBSN characteristics, model, and closed-loop mechanism, followed by an examination of recent TPC studies.

• 무역상무연구
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• 제13권
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• pp.389-409
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• 2000

Recent demands of market forces are causing considerable attention to be forced on logistics functions and revitalizing interest in outsourcing them. The need to efficiently and economically adjust support to meet market demands is growing significantly. Logistics is playing a role it has never played before. In light of this, outsourcing to third parties has become a strategic issue demanding greater attention in corporate boardrooms. From the perspective of TPL users, this paper focuses on how best to make a strategic plan for the effective utilization of TPL. And the results are as follows : First, after deciding their logistics outsourcing, the companies have to set up the aim of TPL through development of logistical strategies. Second, the companies must decide service provider that fits to their business environment and conditions. Third, they have to conclude a contract with logistics service provider. Fourth, after doing the preparatory implementation they carry into effect the original implementation. Fifth, they use the result of original implementation to fix a partnership.