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Optimization of Anti-glycation Effect of ʟ-Carnitine, Pyridoxine Hydrochloride and ᴅʟ-α-Tocopheryl Acetate in an Infant Formula Model System Using Response Surface Methodology (ʟ-Carnitine, pyridoxine hydrochloride, ᴅʟ-α-tocopheryl acetate를 이용한 분유모델시스템의 마이얄반응생성물 저감화 조건 최적화)

  • Jung, Hye-Lim;Nam, Mi-Hyun;Hong, Chung-Oui;Pyo, Min-Cheol;Oh, Jun-Gu;Kim, Young Ki;Choi, You Young;Kwon, Jung Il;Lee, Kwang-Won
    • Korean Journal of Food Science and Technology
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    • v.47 no.1
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    • pp.95-102
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    • 2015
  • The Maillard reaction is a non-enzymatic reaction between amino and carbonyl groups. During milk processing, lactose reacts with milk protein through this reaction. Infant formulas (IFs) are milk-based products processed with heat-treatments, including spray-drying and sterilization. Because IFs contain higher Maillard reaction products (MRPs) than breast milk, formula-fed infants are subject to higher MRP exposure than breast milk-fed ones. In this study, we investigated the optimization of conditions for minimal MRP formation with the addition of $\small{L}$-carnitine ($\small{L}$-car), pyridoxine hydrochloride (PH), and $\small{DL}$-${\alpha}$-tocopheryl acetate (${\alpha}$-T) in an IF model system. MRP formation was monitored by response surface methodology using fluorescence intensity (FI) and 5-hydroxymethylfurfural (HMF) content. The optimal condition for minimizing the formation of MRPs was with $2.3{\mu}M$ $\small{L}$-car, $15.8{\mu}M$ PH, and $20.6{\mu}M$ ${\alpha}$-T. Under this condition, the predicted values were 77.4% FI and 248.7 ppb HMF.

Investigation of Infection Prevention by Dental Hygienist's Personal Protection (치과위생사의 개인방호에 관한 감염방지 실태조사)

  • Kim, Chang-Hee;Jang, Hee-Kyung
    • Journal of dental hygiene science
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    • v.5 no.2
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    • pp.63-70
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    • 2005
  • The relation among the variables of dental hygienists' both personal protection and infection prevention education was investigated in order to identify the necessity of realization of personal protection and utilize in the development of educational programs. The study tools included structured questionnaire and in-home interview. Data analysis included frequency and t-test, and the relations among the variables were as below: (1) Dental hygienist's maskwearing was most well observed in Kyonggi-do (90.0%) by locations, and in the dental hospitals (84.8%) by working places, which was statistically significant. (2) Glove-wearing was most well observed in the university and the higher graduates population (59.1%) by academic background, and in the dental hospital (73.9%) by working place, which was statistically significant. (3) Protection glasses-wearing was most well observed in Guns, Ups, and Myons (82.4%) by locations, which was statistically significant. (4) Uniforms were hand-laundered at home in the 40.9% of the university and the higher graduates, which was statistically significant. (5) About infection management, 67.0% of 2-year college graduates and 71.7% of the respondents from dental hospitals had been educated during their college days, which was statistically significant. (6) About the necessity of infection education, 77.3% of the university graduates responded it is very necessary, which was statistically significant.

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Causes of Right Middle Lobe Syndrome -Recent Experience in Local Tertiary Hospital for Several Years- (우중엽증후군의 원인 -최근 수년간 지역 3차 병원의 경험-)

  • Kim, Hyun Ok;Ma, Jeong Eun;Lee, Seung Jun;Cho, Yu Ji;Jeong, Yi Yeong;Jeon, Kyoung-Nyeo;Kim, Ho Cheol;Lee, Jong Deok;Hwang, Young Sil
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.3
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    • pp.192-196
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    • 2007
  • Background: Right middle lobe syndrome (RMLS) is defined as transient or chronic and recurrent atelectasis of the right middle lobe. Although numerous conditions are associated with RMLS, there are very few recent reports in Korea. This study evaluated the causes of RMLS in a local tertiary hospitalover a period of 42 months. Method: Eighty-eight patients (M:F=64:22, mean age: $67.2{\pm}10.3years$), who had consistent chest radiography findings and underwent bronchoscopy in Gyeongsang University Hospital from January 2003 to July 2006, were enrolled in this study. The clinical characteristics and causes of RMLS in these patients were retrospectively reviewed. Results: The most common symptoms fo RMLS were cough, dyspnea and sputum. Tuberculosis was the most common cause (endobronchial tuberculosis in 22 and pulmonary tuberculosis in 1) The other causes were bronchial stenosis by benign fibrotic changes in 22 cases (25%), anthracofibrosis in 13 cases (14.8%), pneumonia in 11 cases (12.5%), lung cancer in 10 cases (11.4%), mucus impaction in 3 cases (3.4%), bronchiectasis in 2 cases (2.3%) and no demonstrable causes in 7 cases (8%). The bronchoscopy findings were mucosal edema with hyperemic changes in 38 cases (43.2%), mucosal edema with anthracotic pigmentation in 16 cases (18.2%), mucus impaction in 13 cases (14.8%), fibrotic stenosis in 13 cases (14.8%), a mass like lesion in 8 cases (9.1%), exudative necrotic material in 4 cases (4.5%), narrowing as a result of extrinsic compression in 2 cases (2.3%) and no demonstrable abnormalities in 12 cases (13.6%). Conclusion: Right middle lobe syndrome was observed more frequently in patients over the age of 65. The causes were mainly benign diseases with endobronchial tuberculosis being the most common.

A Study on the Operational Method of Urban Arterial With U-Turn (U-Turn을 이용한 간선도로 운영방안)

  • 박용진;손한철
    • Journal of Korean Society of Transportation
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    • v.18 no.1
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    • pp.17-26
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    • 2000
  • U-turns are allowed widely at the intersections by local police department while the left-turn Phases have been gradually Prohibited. However, any strategies for U-turn movements at signalized intersections are unavailable. Therefore, the Purpose of this study is to Propose the efficient operational method of Urban arterial adopting U-turn strategies. Four alternatives are evaluated they are, 1) U-turn movements are allowed at the adjacent intersection with exclusive U-turn lane while the major or the minor approach is Prohibited, 2) U-turn movements are allowed at the adjacent mid-block Pedestrian crossing with exclusive U-turn lane while the major approach is Prohibited. 3) U-turn movements are allowed at the adjacent mid-block Pedestrian crossing with exclusive U-turn lane while the minor approach is prohibited and 4) Comparative one between alternative 3 and 4. From the results of this study, it concludes that the method of U-turn movements allowed at the adjacent mid-block pedestrian crossing with exclusive U-turn lane is the most effective strategy among those alternatives. The strategies of alternative 1 and 4 are Proposed by the boundary based on the major through and left-turn volumes and the minor left-turn volume.

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Analysis of the Insulation Effectiveness of the Thermal Insulator by the Installation Methods (보온단열재의 설치방법에 따른 보온성 효과 분석)

  • Kim, Young-Bok;Lee, Si-Young;Jeong, Byoung-Ryong
    • Journal of Bio-Environment Control
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    • v.18 no.4
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    • pp.332-340
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    • 2009
  • In this study, the thermal insulation effectiveness of the greenhouse insulators by the installation methods was investigated to find the right installation way of the insulation materials. Physical properties of the insulators such as thickness, air transmissivity, apparent density, ultraviolet rays cutoff ratio, reflectance, thermal conductivity, moisture absorptivity were evaluated and the insulation ability of the insulators were measured by the module experiments. For the same insulator, the insulation ability of the case with the outward direction of the black colored face, i.e., with the inward direction of the white colored face, was better than that of vice versa. The case of the black colored both surfaces was better than the case of the white colored both surfaces. For aluminium reflection material, the case with the outward direction of the lustre face, i.e., with the inward direction of the non-lustre face, was better than that of vice versa. For the same material with the inner thin polyethylene foam (or polyester) and the chemical wool, the case with the outward direction of the inner thin polyethylene foam (or polyester), i.e., with the inward chemical wool, was better than that of vice versa. Addition of the inner thin polyethylene foam increased the insulation effect very much.

Incubation Conditions Affecting Bacteriocin Production of Lactobacillus plantarum K11 Isolated from Dongchimi (동치미에서 분리된 Lactobacillus plantarum K11의 박테리오신 생산에 영향을 미치는 배양 조건)

  • Lim, Sung-Mee;Lee, Gun-Ja;Park, Sun-Mee;Im, Dong-Soon
    • Journal of Food Hygiene and Safety
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    • v.23 no.2
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    • pp.113-120
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    • 2008
  • The influence of incubation temperature, pH and media components on bacteriocin production by Lactobacillus plantarum K11 were investigated. The highest activity was observed in MRS broth, but no bacteriocin activity was obtained in TSB. The bacteriocin was produced from the exponential growth phase and its activity also reached a maximum in MRS broth, but then dropped after 16 hr because of degradation by extracellular proteolytic enzymes or exhaustion of medium nutrients. The optimal temperature and pH for production of bacteriocin were $37^{\circ}C$ and pH 7.0 in MRS broth, respectively. The addition of 0.5 or 1.0% glucose and $0.5{\sim}1.5%$ lactose to MRS resulted in the increase of the bacteriocin production. With 0.5% NaCl and $K_2HPO_4$, the activities were significantly higher than that of control, respectively. However, increasing nitrogen sources such as beef extract, casein, and tryptone and salts such as $NH_4PO_4$, $MgSO_47H_2O$, and $MnSO_4H_2O$, had detected a negative influence upon the bacteriocin production. Consequently, because the bacteriocin produced by L. plantarum K11 was affected by various incubation conditions, the bacteriocin activity of L. plantarum K11 applied in food as a novel starter will be dependent on environmental factors such as fermentation conditions and food ingredients.

Long-Term Effects of the DHA Supplementation on Physical and Brain Development in Full-Term Infants (장기간에 걸친 DHA 보충이 영아의 신체발육 및 두뇌발달에 미치는 영향)

  • 정현주
    • Journal of Nutrition and Health
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    • v.31 no.8
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    • pp.1295-1306
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    • 1998
  • Recent research indicates that the n-3 fatty acid , docosahexaenoic acid(22 : 6n 3, DHA) plays an essential role in infant brain development . DHA is highly concentrated in brain and retinal tissues and accumulates during late fetal and early neonatal life. Diets deficient in DHA are associated with reduced levels of DHA in brain and retinal tissues. The purpose of this study is to investigate the long term effects of DHA supplementation on the growth and mental development of full-term infants. THirty four healty infants were recruited from those who were delivered at Kyung Hee Medical Center. The experimental groups were the breast milk+DHA(-) group who were fed human milk for 20 weeks after birth and thereafter were fed placebo formula for 28 weeks, the breast milk+DHA(+) group who were fed human milk for 20 weeks after birth and thereafter were fed DHA supplemented formula for 28 weeks, DHA(-) group who were fed placebo formula for 48 weeks, and DHA(+) group who were fed DHA supplemented formula for 48 weeks. The daily average intake of DHA for the breast milk+DHA(-) , breast milk+DHA(+), DHA(-) and DHA(+) groups were 39.1mg, 89.9mg, 17.7mg, and 160.224mg, respectively. The results showed that measurements of infant weight, length, head, and chest circumferncewere all in normal range and they were not influenced by the DHA supplements in their diets. There was a significant correlation between dietary DHA intake and erythrocyte DHA level. The results of flash visual evoke potential (VEP) test were not correlated with eerythrocyte DHA and dietary DHA levels at 48 weeks of age. No differences were found in Bayley mental and Psychomotor Development lndex scores among the four experimental groups at 48 weeks of age. Unlike the short-term effects there was no long-term effect of relatively small amounts of dietary DHA supplements on the scores for flash VEP and Bayley test, even thour호 there was an elevated DHA supplements on the scores for flash VEP and Bayley test, even through there was an elevated DHA content in the infants erythrocytes.

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Studies on the Chemical Compositions of Citrus junos in Korea (한국산유자(韓國産柚子)의 화학적성분(化學的成分)에 관(關)한 연구(硏究))

  • Jung, Ji-Heun
    • Applied Biological Chemistry
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    • v.17 no.1
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    • pp.63-80
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    • 1974
  • The chemical components of Citrus junos produced in Korea were divided into two parts; common and special components respectively. In the former the relation between the physiological effects of the plant and its ripening process was observed periodically while the latter was analyzed the ripening fruits for their effective utilization as food. The results are summarized as follows: 1. The analytical result of seasonal change showed that the rind ratio was higher than the flesh ratio and on a regional basis, the rind ratio was higher in the islands than on land areas. 2. In the experiment the moisture was increased until the third period, but afterwards it was made constant. While the content of crude fat, cellulose, ash, total acid and soluble non-nitrogen material were decreased until the third period and the cotent of cellulose and total acid were continuousely redused until the last period. In con trast with the above the content of reducing sugars was increased but the content of crude fat, cellulose, ash, crude protein and soluble non-nitrogen material were increased until last period. 3. The content of vitamin C was richer in the rind than in the flesh, in the Korean species than in the Japanese. 4. Free sugars; xylose, fructose, glucose were richer in the rind than in the flesh. 5. The content of volatile organic acids was richer in the rind than in the flesh. Among them, volatile acids, acetic acid, formic and n-valeric acid were found in the rind and formic acid, acetic acid and propionic acid were deteceed in the flesh. 6. The total content of non-volatile acids was richer in the flesh than in the rind. In the kind of non-volatile acids, citric acid,glutaric acid, malic acid, tartaric acid, oxalic acid, malonic acid, succinic acid and an unknown acid were found in the rind and citric acid, malic acid, succinic acid, oxalic acid, glutaric acid and malonic acid in the flesh. 7. Three kinds of aromatic components: D-limonene, ${\alpha}-pinene$, p-cymene and seven other kinds of unknown aromatic components were detected in neutral essential oils. Among them, D-limonene seemed to be main aromatic component in the fruits. 8. From the above results it is confirmed that both rind and flesh of the ripened fruit could be utilized for food effectively, and unripened fruits are suitable for producing citric acid, ripened fruits are also useful for producing juice.

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Evaluation of Biological Control of Liriomyza trifolii (Burgess) (Diptera: Agromyzidae) using Diglyphus isaea (Walker) (Hymenoptera: Eulophidae) in Three Seasonal Culture Types of Tomato Greenhouse (굴파리좀벌(Diglyphus isaea)을 이용한 시설재배 토마토 작형별 아메리카잎굴파리(Liriomyza trifolii) 밀도억제 효과)

  • Kim, Jeong-Hwan;Byoun, Young-Woong;Lee, Gwan-Seok;Kim, Hwang-Yong
    • Korean journal of applied entomology
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    • v.46 no.1 s.145
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    • pp.71-78
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    • 2007
  • Biological control of Liriomyza trifolii (Burgess) using Diglyphus isaea (Walker) has been evaluated in tomato greenhouse, for three seasonal culture types: spring type (March-July), summer type (June-October) and autumn type (July-December). For spring type, totally 5.8 $individuals/m^2$ of D. isaea has been released at six times from late April, when the density of L. trifolii was about 1.0 individuals/plant. Corrected mortality of Liriomyza trifolii caused by parasitoids was 97.6% at early July, and the proportion of D. isaea was 88.9% of all parasitoids collected in the greenhouse. In the case of summer type, totally 1.8 $individuals/m^2$ of D. isaea has been released at five times from early July, when the density of 1. trifolii was about 0.4 individuals/plant. Corrected mortality of L. trifolii caused by parasitoids was 84.4% during the whole season, but the proportion of D. isaea was very low (only 13.8%). Immigrating parasitoids such as Chrysocharis penthus were synchronized to control the leafminer in the greenhouse. For autumn type, totally 2.7$individuals/m^2$ of D. isaea has been released at four times from mid September, when the density of L. trifolii was about 0.7 individuals/plant. Corrected mortality of f. trifolii caused by parasitoids was 85.7% at mid December, and the proportion of the D. isaea was 83.4%.

Preference and Utilization of Instant Foods of University Students Studying Tourism Science (관광학 전공 대학생의 즉석 가공식품 기호도와 이용도)

  • 서경화;윤혜현
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.356-364
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    • 2004
  • The preference and frequency of use on instant foods were investigated for university students studying tourism science. The most preferred instant food group was noodles, and Tangs, Baps, Gooks, Zooks, one-dishfoods were preferred in order. The most preferred instant food was Cupramyeon. The preference score on instant foods of Tangs, Gooks and One dish foods for male students significantly was higher than that of female students. Also, students majoring non-cooking like instant food more than those majoring culinary science (p<0.05). The highest frequency of use was shown in group of Baps and noodles, followed by one-dish food, Gooks, Tangs, Zooks in order. The largest number of students answered 'TV' and 'curiosity' to the question on the motives of use. The most students Purchased instant foods at 'convenience store' and 'small retail store'.