• Title/Summary/Keyword: TO-14

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A Study of Pre-application of Neuromuscular Electrical Stimulation on Atrophic Muscle Function (신경근 전기자극의 사전적용이 위축근 기능에 미치는 영향)

  • Kang, Jong-Ho;Kim, Yong-Nam
    • The Journal of the Korea Contents Association
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    • v.9 no.12
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    • pp.691-698
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    • 2009
  • The purpose of this study was to examine the effect of neuromuscular electrical stimulation(LFES) during hindlimb suspension on weight and function of rat hindlimb muscles. Sprague-Dawley rats(body weight 300-350g) were randomly assigned to five groups: a HLS(n=5) that were hindlimb suspended for 14 days, a WB(n=5) that kept as control, a ES14 that were hind limb suspended for 14days with pre-application of LFES for 14 days, ES11 that were hindlimb suspended for 14 days with pre-application of LFES for 11 days, a LFES 7 that were hindlimb suspended for 14 days with pre-application of LFES for 7 days. Gastrocnemius muscle weight, stride length were significantly decreased and toe out angle were significantly increased in HLS and ES7 groups, whereas muscle weight, stride length, toe out angle were maintained in ES14, ES11. this indicated that LFES for 14 days, LFES for 11 days could prevent muscle atrophy and retain function.

Computer Simulation of Enhancement of Coerciviy in Nd-Fe-B/(Nd,Dy)-Fe-B Composite Magnets

  • Kawasaki, Kohei;Yanai, Takeshi;Nakano, Masaki;Fukunaga, Hirotoshi
    • Journal of Magnetics
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    • v.16 no.2
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    • pp.145-149
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    • 2011
  • The coercivity $H_c$ of $Nd_2Fe_{14}B$ magnets and $Nd_2Fe_{14}B/(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ composite magnets were calculated by computer simulation based on the micromagnetic theory under assumptions that $Nd_2Fe_{14}B$ and $(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ grains have magnetically deteriorated layers on their surfaces and diffusion of Dy from $(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ grains to $Nd_2Fe_{14}B$ ones through the contacting boundaries recovers the magnetic anisotropy of the deteriorated layers of $Nd_2Fe_{14}B$ grains. $H_c$ of $Nd_2Fe_{14}B/(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ composite magnets increased by the diffusion of Dy from $(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ grains to $Nd_2Fe_{14}B$ ones and the resultant recovery of the anisotropy field of deteriorated layers of $Nd_2Fe_{14}B$ grains. The $H_c$ vs fraction of $(Nd_{0.7}Dy_{0.3})_2Fe_{14}B$ grains curve were convex for the magnets with the degree of alignment between 0.94 and 0.99, which suggests that the above composite magnets have larger $H_c$ values than the alloy-magnets with the same Dy content, and that we can save the consumption of Dy by using these composite magnets.

Determination of $^{14}C$ in Environmental Samples Using $CO_2$ Absorption Method ($Co_2$ 흡수법에 의한 환경시료중 $^{14}C$ 정량)

  • Lee, Sang-Kuk;Kim, Chang-Kyu;Kim, Cheol-Su;Kim, Yong-Jae;Rho, Byung-Hwan,
    • Journal of Radiation Protection and Research
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    • v.22 no.1
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    • pp.35-46
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    • 1997
  • A simple and precise method of $^{14}C$ was developed to analyze $^{14}C$ in the environment samples using a commercially available $^{14}CO_2$ absorbent and a liquid scintillation counter. An air sampler and a combustion system were developed to collect HTO and $^{14}CO_2$ in the air and the biological samples simultaneously. The collection yield of $^{14}CO_2$ by the air sampler was in the range of 73-89% . The yield of the combustion system was 97%. In preparing samples for counting, the optimum ratio of $CO_2$ absorbent to the scintillator for mixing was 1:1. No variation of the specific activity of $^{14}C$ in the counting sample was observed up to 70 days after preparation of the samples. The detection limit for$^{14}C$ was 0.025 Bq/gC, which is the level applicable to the natural level of $^{14}C$. The analytical result of $^{14}C$ obtained by the present method were within ${\pm}6%$ of the relative error from the one by the benzene synthesis. The specific activity of $^{14}C$ in the air collected at Taejon during the period of October 1996 ranged from 0.26 to 0.27 Bq/gC. The specific activity of $^{14}C$ in the air collected at 1km from the Wolsong nuclear power plant a 679 MWe PHWR, was $0.54{\pm}0.03$ Bq/gC. The ranges of specific activities of $^{14}C$ in the pine needles and the vegetations from the areas around the Wolsong nuclear power plant were 0.56-0.67 Bq/gC and 0.23-1.41 Bq/gC, respectively.

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Bioavailability Soil-aged Residues of the Herbicide Bentazon to Rice Plants (토양중(土壤中) 신생(新生) 및 숙성(熟成) Bentazon 잔유물(殘油物)의 벼에 의(依)한 흡수(吸收))

  • Lee, Jae-Koo;Kyung, Kee-Sung;Fuhr, F.
    • Applied Biological Chemistry
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    • v.32 no.4
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    • pp.393-400
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    • 1989
  • The amounts of $^{14}CO_2$ evolved during the $^{14}C-bentazon$ aging in soil for 3 and 6 months were 6.1 and 14.8% of the original radioactivity, respectively. The presence of earthworms in soil tended to increase the uptake of $^{14}C-bentazon$ by the roots of rice plants, even if it was not statistically significant. The evolution of $^{14}CO_2$ from $^{14}C-bentazon$ in soil increased in the presence of rice plants and earthworms compared with in the absence of them. The uptake of $^{14}C-bentazon$ residues by rice plants decreased remarkably with increasing the aging period within the limit of 3 months both in the absence and presence of earthworms, but there is not much difference between 3-month-aging and 6-month-aging. Much larger amounts of $^{14}C-labelled$ compounds were translocated to the shoots, compared with the data from a previous investigation using maize plants. The amount of non-extractable bound residue increased remarkably with the aging period up to 3 months. The polarity of the compounds extracted from soil increased with the aging and the growing of rice plants, indicating the formation of some polar metabolites.

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The Distribution of $^{14}C-chitosan$ by Different Molecular Weight in Mice (마우스에서 $^{14}C-chitosan$ 분자량별 체내 분포에 관한 연구)

  • Kim, Kwang-Yoon;Kim, Young-Ho;Kim, Hee-Kyung;Bom, Hee-Seung;Kim, Ji-Yeul;Roh, Young-Bok;Nishimura, Yoshikazu
    • Journal of Radiation Protection and Research
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    • v.23 no.2
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    • pp.83-88
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    • 1998
  • Chitosan is a nontoxic natural chealtor which was made by chitin, and reduced a contamination of radiostrontium in animals. In this experiment, A different molecular weight of C-14 chitosan was intravenously administered to mice, and then the distribution of C-14 chitosan in the body was observed. Male mice (8 to 10 weeks, body weight of 30 to 35g) of ICR strain were used. C-14 chitosan was diluted with saline and then given intravenously in mice. After the administration of C-14 chitosan, mice was sacrificed at the 6th hour, 1st, 3rd, 5th, and 7th day. Beta radioactivities in the blood, liver, kidney, liver, muscle, testis, and urine was measured using a liquid scintillation analyzer. Most of the C-14 chitosan was excreted through urine within 6 hours. Biodistribution of C-14 chitosan was similar despite the difference of moleclar weight. Higher distributions of radioactivities were found in the liver, kidney, spleen. The relative concentration in tissue increased for the 6 hours and then decreased. In conclusion, most of C-14 chitosan was excreted through urine despite the difference of molecular weight. and, low molecular weight of C-14 chitosan showed higher distribution than high molecular weight of C-14 chitosan in tissues.

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Growth and gut performance of young pigs in response to different dietary cellulose concentration and rearing condition

  • Cho, Hyun Min;Kim, Eunjoo;Wickramasuriya, Samiru Sudharaka;Shin, Taeg Kyun;Heo, Jung Min
    • Animal Bioscience
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    • v.34 no.10
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    • pp.1653-1662
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    • 2021
  • Objective: This experiment was conducted to investigate the effect of insoluble cellulose supplementation to diets on the growth performance, intestinal morphology, the incidence of diarrhea, nutrients digestibility, and inflammatory responses in altering environmental conditions of animals housing. Methods: A total of 108 male pigs (Duroc×[Yorkshire×Landrace]) were randomly allocated to one of three dietary treatments (cellulose 0%, 1%, 2%) and two environmental conditions (good sanitary condition vs. poor sanitary condition) to give 6 replicate pens per treatment with three pigs per each pen at 14 days post-weaning. Results: Pigs were in good sanitary condition had higher average daily gain (p<0.01) and improved feed efficiency (p<0.05) from day 1 to 14 after weaning compared to their counterparts. The interactions were found between environmental conditions and dietary treatments (day 7: crypt depth [p<0.01], villous height to crypt depth [p<0.001]; day 14: crypt depth [p<0.001], villous to crypt ratio [p<0.01]) in ileum morphology. Crypt depth was decreased (p<0.05), and villous to crypt ratio was increased (p<0.05) only in poor sanitary conditions. Pigs exposed to the good sanitary condition had higher (p<0.05) apparent ileal digestibility (day 7, gross energy; day 14, dry matter), apparent total tract digestibility (day 14, dry matter and crude protein) compared to pigs housed in the poor sanitary condition. Meanwhile, pigs fed a diet supplemented with 2% cellulose had decreased (p<0.05) apparent ileal digestibility (day 7, dry matter; day 14, crude protein), apparent total tract digestibility (day 7, dry matter; day 14, crude protein, gross energy) compared to pigs fed a diet supplemented with 0% or 1% cellulose. Conclusion: Our results indicated that a diet supplemented with 1% cellulose increased villous to crypt ratio, however feeding a diet containing cellulose (1% or 2%) impaired nutrient digestibility for 14 day after weaning in both good sanitary and poor sanitary conditions.

Thalidomide Combined with Chemotherapy in Treating Patients with Advanced lung Cancer

  • Li, Li;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2583-2585
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    • 2016
  • Objectives: To evaluate efficacy and toxicity in patients with advanced lung cancer, including non-small cell and small cell variants (NSCLC and SCLC), treated with thalidomide plus chemotherapy. Methods: Fourteen patients with advanced lung cancer were scheduled to receive chemotherapy combined with thalidomide. All patients in this study received thalidomide (100 mg orally per night before sleeping, produced by Changzhou Pharmaceutical Factory Co.Ltd) after the start of chemotherapy for at least 14 days. Chemotherapy was administered according to the condition of patients. After at least 14 days of treatment, efficacy and toxicity were evaluated. Results: There were 6 female and 8 male patients with advanced lung cancer recruited into this study, including 2 with SCLC and 12 with NSCLC. The median age was 56.7 (44-65) years. Progressive disease was observed in 12 patients (12/14), and stable disease in 2 (2/14). Grade 1 to 2 myelosuppression was observed in 4/14 patients, and Grade 1 to 2 elevation of hepatic enzymes was recorded in 5/14 patients. Adverse effects on the gastrointestinal tract were documented in 2/14 patients, all beingGrade 1. No Grade 3-4 toxicity was recorded. No treatment related deaths occurred. Conclusions: Our results demonstrate that thalidomide combined with chemotherapy is mildly effective and safe for treating patients with advanced lung cancer. However, further evaluation of this combination is warranted.

A Rapid Method for the Measurement of the Absolute Activity of Carbon-14 in Pea Plant Tissue

  • Kendall, F.H.;Park, Chang-Kyu;Mer, C.L.
    • Applied Biological Chemistry
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    • v.18 no.2
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    • pp.56-60
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    • 1975
  • A rapid method for the measurement of the absolute activity of carbon-14 in cotyledons and root of etiolated pea seedlings has been developed. Fresh tissue was frozen in liquid air, ground and suspended in gel phosphor and subjected to measurement for its radioactivity by liquid scintillation counter. Apparent activity of the suspended tissue sample calculated by counting efficiency value obtained by internal standardisation, was found to be related to absolute activity of the tissue, determined by flask combustion technique, by a constant factor. Once this factor is determined experimentally, analysis of C-14 lebelled tissue involves only fairly simple suspension counting by liquid scintillation counter. Present method appears to be applicable to other tissues tagged with C-14.

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Accuracy of 14 intraoral scanners for the All-on-4 treatment concept: a comparative in vitro study

  • Gozde, Kaya;Caglar, Bilmenoglu
    • The Journal of Advanced Prosthodontics
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    • v.14 no.6
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    • pp.388-398
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    • 2022
  • PURPOSE. This in vitro study aimed to evaluate the accuracy of 14 different intraoral scanners for the All-on-4 treatment concept. MATERIALS AND METHODS. Four implants were placed in regions 13, 16, 23, and 26 of an edentulous maxillary model that was poured with scannable Type 4 gypsum to imitate the All-on-4 concept. The cast was scanned 10 times for each of 14 intraoral scanners (Primescan, iTero 2, iTero 5D, Virtuo Vivo, Trios 3, Trios 4, CS3600, CS3700, Emerald, Emerald S, Medit i500, BenQ BIS-I, Heron IOS, and Aadva IOS 100P) after the polyether ether ketone scanbody was placed. For the control group, the gypsum model was scanned 10 times with an industrial scanner. The first of the 10 virtual models obtained from the industrial model was chosen as the reference model. For trueness, the data of the 14 dental scanners were superimposed with the reference model; for precision, the data of all 14 scanners were superimposed within the groups. Statistical analyses were performed using the Kolmogorov-Smirnov, Shapiro-Wilks, and Dunn's tests. RESULTS. Primescan showed the highest trueness and precision values (P < .005), followed by the iTero 5D scanner (P < .005). CONCLUSION. Some of these digital scanners can be used to make impressions within the All-on-4 concept. However, the possibility of data loss due to artifacts, reflections, and the inability to combine the data should be considered.

Destructive Examination of 3 Cycle Burned 14$\times$14 PWR Fuel (삼주기연소 14$\times$14 PWR 핵연료의 핫셀 파괴시험)

  • 이기순;유길성;이영길;민덕기;서항석
    • Nuclear Engineering and Technology
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    • v.21 no.4
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    • pp.332-340
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    • 1989
  • Destructive examination of 14$\times$14 PWR fuel burned for 3 cycles are carried out to investigate the in-reactor fuel performance. The results obtained are as follows; 1) Grain growth is not occured at the fuel center. 2) Fuel density is decreased as the turnup increase, the density is down to 94.4% TD at burnup of 36,000 MWD/MTU. 3) Average thickness of oxide layer on cladding is less than 10 $\mu$m in the lower and middle section, while it is rapidly increased above 20 $\mu$m in the upper section. 4) The rate of hydride production in the cladding is large in the upper section than lower section and is related to the production of oxide on the cladding

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