• Journal of Society of Preventive Korean Medicine
• /
• v.21 no.3
• /
• pp.1-10
• /
• 2017

Objectives : The purpose of this study is to investigate the practice patterns of traditional Korean medicine (TKM) doctors and the acceptance of payment model in order to develop a new TKM health insurance payment model linked with TKM clinical practice guidelines (CPGs). Methods : Lumbar herniated intervertebral disc (HIVD) and idiopathic facial palsy (IFP) were selected as a test diseases to develop a new TKM payment model. The level of benefit coverage in the National Health Insurance (NHI) was designed. The survey asked 228 TKM doctors about their practice patterns in HIVD and IFP patients and acceptance of new payment model. Results : Mean of medical cost for treatment of HIVD was 441,000 KW, mean of treatment period ranged from 4.9 to 17.5 weeks, and mean of number of treatment ranged from 14.6 to 50.4 HIVD patients. In the case of IFP, mean of medical cost for treatment of IFP was 468,000 KW, mean of treatment period was at least 4.2 and up to 15.9 weeks and mean of number of treatment ranged from 14.2 to 52 IFP patients. Conclusions : Current study suggests that mixed payment model of per-visit and episode-based model seem to be proper. The model 1 bundles both items which were covered and not covered by NHI in a rational way. The model 2 is based on the development and application of critical pathway. Lastly, model 3 suggests bundling of items covered by current NHI. Acceptance of TKM doctors is expected to be highest in the model 3.

• Journal of Information Management
• /
• v.40 no.4
• /
• pp.93-108
• /
• 2009

In order to achieve the growth of traditional Chinese medicine, the chinese government has annually released "China Statistical Yearbook of Chinese Medicine" to the world since "State Administration of Traditional Chinese Medicine of the People's Republic of China" established in 1988. It is believed that the chinese government intends to secure the early dominance of the global medical market by systematic management of its own medicine infrastructures. Although the statistics of "China Statistical Yearbook of Chinese Medicine" weren't systematically organized at the beginning, it has becoming richer, more systematic, and more standardized in the data construction and system as time has passed. Furthermore, we can take a look at China's effort to take the initiative of oriental medicine by expanding investment in several core areas - medicine resources, operation of medical instruments, service, medicine education, medicine science research, and working expenses. This article will show how china has been trying to develop the chinese medicine, focusing on two parts. One is specific analysis of the book "China Statistical Yearbook of Chinese Medicine". It is divided into analysis of its construction system, the degree of data construction, and its statistical system. The other is analysis of annual changes in areas of medicine resources, operation of medical instruments, service, medicine education, medicine science research, and working expenses.

• Korean Journal of Pharmacognosy
• /
• v.41 no.3
• /
• pp.216-220
• /
• 2010

Obesity is an important risk factor that significantly increases mortality and disease rates in the cardiovascular disease, diabetes, and various diseases. So far, the most powerful way to inhibit fat absorption is pancreatic lipase inhibitors. In this study, we investigated the anti-obesity effect of the extract of Juniperus rigida. Juniperus rigida extract (JRE) had a inhibitory effect on pancreatic lipase activity ($IC_{50}$=8.63 ${\mu}g$/ml). In in vivo oil-emulsion loading test, this extract also inhibited the intestinal fat absorption. In addition, we measured inhibitory effects of JRE on activity of phosphodiesterase (PDE) and hormone sensitive lipase (HSL) among the important enzymes associated with lipolysis. JRE strongly inhibited PDE activity ($IC_{50}$=4.56 ${\mu}g$/ml), whereas inhibitory effect on HSL activity was very weak compared with orlistat. As a result, JRE inhibited the absorption of fat by inhibiting the activity of pancreatic lipase and induced lipolysis through inhibition of PDE activity. Therefore, we suggest that Juniperus rigida may be a potential therapeutic agent improving obesity.

• Journal of the Korea Convergence Society
• /
• v.10 no.3
• /
• pp.127-133
• /
• 2019

The ami of our study was on the anti-obesity effect of ethanol extract from Trichosanthes kirilowii Maxim root (TKM) in murine adipocytes, 3T3-L1 cells. This study focused on anti-adipogenic activity through inhibition of cell differentiation in 3T3-L1 cells treated TKM. 100 ug/ml of non-cytotoxic TEM remarkablely inhibited content of triglycerol and suppressed expressions of $C/EBP{\alpha}$, $PPAR{\gamma}a$ and SREBP-1c related with lipogenic transcription factors in theres 3T3-L1 cells compared to (-)control cells. As phosphorylations of AMPK and ACC were incerased, HSL and CPT-1 mRNA expression increased upon TKM treatment, which involved in inhibition of fatty acid synthase expression. In conclusion, these results indicate that TKM can inhibit mRNA and protein expression of lipogenic genes in 3T3-L1 adipocytes. Our study suggests that TKM has potential anti-obesity effects and is a convergence therapeutic functional agent with anti-adipogenic activity via hypolipogenesis.

• Journal of Society of Preventive Korean Medicine
• /
• v.20 no.1
• /
• pp.29-42
• /
• 2016

Objectives : The aim of this study is to review studies that utilized domestic secondary data in Traditional Korean Medicine (TKM). Methods : We identified variables and values related to TKM of 24 secondary data sources, and searched studies from 6 databases (PubMed, RISS, KISS, NDSL, KMBASE, OASIS). Results : There were 13 secondary data sources including variables and values related TKM, and 23 articles were included in this study. Conclusions : It is necessary to develop high-quality secondary data sources that are suitable to TKM system in accordance with national policy.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.25 no.5
• /
• pp.894-899
• /
• 2011

Traditional Korean Medicine (TKM) has been actively researched through various approaches, including computational methods. This paper aims at providing an overview of domestic studies using the computational techniques in TKM field. A literature search was conducted in Korean publications using OASIS system, and major studies of data mining in TKM were identified. A review was presented in six diagnosis fields, including sasang constitution diagnosis, eight constitution diagnosis, tongue diagnosis, pattern diagnosis for stroke, diagnosis based on ontology, diagnosis for cause of disease. They collect clinical data themselves for experiments and primarily applied a algorithm of decision tree, SVM, neural network, case-based reasoning, ontology reasoning, discriminant analysis. In the future, there needs to identify which algorithm is suitable to diagnosis or other fields of TKM.

• Journal of Oriental Medical Thermology
• /
• v.6 no.1
• /
• pp.39-48
• /
• 2008

Purpose: The purpose of this study is to report the effect of TKM to Rhumatitis Arthritis after parturition and show the importance of recuperation after parturation. Methods: The patient was a 33-year-old woman who complains arthralgia, edema and sense of coldness after her third parturation. The patient was treated by Herb medicine, Acupuncture treatment, Moxa treatment and Physical Treatment. And the progress of symtoms was evaluated by cheking the change of VAS, and inspecting the DITI. Results: The Pain and edema have declined. After discharge, she got definite diagnosis as Rhumatitis Arthritis. But We already estimated it from the results of serum test. So we had treated the patience with TKM and we could explain the prognosis. We regulated the pain and edema successfully at the acute phase. And the patient could take care of herself, she didn't play her disease down as a simple symptoms of parturation. Conclusion: TKM is expected to have positive effect on Rheumatic arthritis with quick onset after parturation.

• The Journal of Korean Medicine
• /
• v.26 no.2 s.62
• /
• pp.182-194
• /
• 2005

Objectives: After the discontinuance of the Women's Health Initiative (WHI)clinical trial in the U.S. in July 2002, I thought that the domestic medical field would come to a crisis in hormonal treatment for perimenopausal and postmenopausal women. However, the domestic condition of HRT has barely changed. This study was designed to investigate world research trends in HRT and bring forward the response of the Traditional Korean Medicine (TKM) Research Group. Methods: I investigated recent domestic ;md world research trends about HRT and climacteric syndrome. Based on this analysis, I predicted western medical research trends and direction for HRT and medical care of perimenopausal and postmenopausal women. Results and Conclusions: I propose that we (TKM Research Group) have to explain the side effects of HRT for postmenopausal women and try to suggest complementary therapy for it. For that aim, the Association of Korean Medicine's effort is very important, as well as personal practitioner's actions.

• Korean Journal of Pharmacognosy
• /
• v.40 no.4
• /
• pp.388-393
• /
• 2009

Advanced glycation end products (AGEs) have been implicated in the development of diabetic complications. The AGEs inhibitors or cross-link breakers attenuate various functional and structural manifestations of diabetic complications. In this study, 64 herbal medicines from China and Vietnam have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, eight herbal medicines ($IC_{50}$<50 ${\mu}g$/ml) were found to have strong AGEs inhibitory activity compared with aminoguanidine (14 days, $IC_{50}$=75.98 ${\mu}g$/ml; 28 days, $IC_{50}$=88.27 ${\mu}g$/ml). Particularly, four herbal medicines, Buddleja officinalis (whole plant), Syzygium cuminii (leaf), Eugenia caryophyllate (seed), and Paeonia suffruticosa (root) showed more potent inhibitory activity (approximately 5-6 fold) than the positive control aminoguanidine.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.19 no.3
• /
• pp.267-276
• /
• 2006

Purpose : The purpose of this study was to investigate the clinical application of Traditional Korean Medicine(TKM) treatment to climacteric symptoms after hysterectomy. Methods : The patient was a 51-years-old woman who suffered from hot flush, arthralgia, fatigue et al after hysterectomy. The patient was treated by TKM such as herb medication and acupuncture therapy. And her health status was evaluated by Kupperman's index and Medical Outcome Study Short Form 36( SF-36). Results : Climacteric symptoms after hysterectomy was reduced( Kupperman's index from 40 to 20). It got better that Physical Functioning(PF), General health(GH), Bodily pain(BP), Role limitation-Emotion(RE) and Mental Health(MH). So, it means that her health status was improved. Conclusion : TKM is expected to have positive effects on climacteric symptoms after hysterectomy, and can be improve woman's health status after hysterectomy.