• The Journal of Pediatrics of Korean Medicine
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• v.31 no.4
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• pp.9-18
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• 2017

Objectives The purpose of this study is to investigate the recent Korean medicine treatment and study trends of tic disorder by reviewing clinical studies. Methods The clinical studies of Korean medicine treatment for tic disorder were obtained from National Discovery for Science Leader (NDSL), Research Information Sharing Service (RISS), Korean Traditional Knowledge Portal (KTKP) and Oriental Medicine Advanced Searching Integrated System (OASIS). Results 15 articles were analyzed to find out the most commonly used herbal medicine, acupoints, other Korean medicine treatments and evaluation methods. Conclusions This study shows some common Korean medicine treatment methods for tic disorder which can be used for further research.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.21 no.3
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• pp.133-140
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• 2010

Tic disorders, including Tourette syndrome, are known as neurobiologic disorders and as such, much emphasis has been placed on isolating genetic determinants. Although previous reports involving studies of discordance among monozygotic twins have shown the importance of genetic predisposition, they have also supported a role for environmental factors in the development of tic disorders. Therefore, it is important to consider that both genetic and environmental factors contribute to their clinical expression. The goal of this article was to review recent reports regarding the role of environmental factors in development and progression of tics. Specific environmental factors associated either with a more severe course of illness or improved outcomes were discussed. Given that accumulating evidence had suggested the usefulness of behavior therapies in the suppression of tic disorders, particular emphasis was placed on the impact of several contextual factors.

• Journal of TMJ Balancing Medicine
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• v.4 no.1
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• pp.12-16
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• 2014

Therapeutic effect of Yinyang Balancing Appliance of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance was observed in chronic motor tic disorder. One chronic motor tic Disorder case was managed with the Yinyang Balancing appliance on tempromandibular joint (TMJ), combined with acupuncture. Clinical outcome measurement was based on subjective measures and clinical observations. The patient showed positive changes after the treatment and this effect maintained over the follow-up period. Although it is not clear the effect is sustaining or temporary in its nature, a positive effect was observed and further clinical and biological research on FCST is expected.

• Journal of TMJ Balancing Medicine
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• v.6 no.1
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• pp.19-23
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• 2016

Therapeutic effect of Yinyang Balancing Appliance of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance was observed in tic disorder patients. Seventy tic disorder cases were managed with the Yinyang Balancing Appliance on temporomandibular joint (TMJ), combined with acupuncture. Clinical outcome measurement was based on subjective measures and overall clinical impressions. Patients showed a trend toward improvement by clinical observations. In some cases, such changes were visible even after the initial treatment, and this effect was observed to be maintained over the follow-up period. Further clinical and biological research on tic disorder is expected with respect to the FCST.

• Journal of TMJ Balancing Medicine
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• v.11 no.1
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• pp.25-36
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• 2021

It was observed that the effectiveness of Yin-yang balancing therapy of the tempromandibular joint (YBT) or functional cerebrospinal therapy (FCS) in three cases: an acute and a chronic motor tic disorder and a Tourrette's disorder (TD). These three cases were mainly managed with cervical balancing appliance for the Yin-yang Balancing on tempromandibular joint (TMJ) and pelvic balance therapy. They were treated concurrently with acupuncture, cupping and herb-medicine. Clinical outcome measurement was based on subjective measures with visual analogue scale (VAS), Yale Global Tic Severity Scale (YGTTS) and clinical observations for 235, 279 and 273 days respectively. The patient showed positive changes after the treatment and this effect maintained over the follow-up period. Although it is not clear whether the effect is sustained afterwards or not, a positive effect on the motor tic disorders and TD was observed. And so, furthermore strict clinical and structural researches for verification on YBT is expected.

• The Journal of Korean Medicine
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• v.42 no.3
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• pp.139-152
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• 2021

Objectives: The purpose of this review is to investigate the latest traditional Chinese medicine clinical studies on pediatric tic disorder with Tuina treatment and propose the directions of future studies and clinical applications. Methods: To obtain data from CNKI, set the field by '中醫學', '中藥', '中西醫結合' and used keywords '抽动障碍', '抽動穢語綜合', '小兒抽动', '兒童抽动' and '推拿', '導引', '按摩', 'Tuina', 'massage' in cross combination way. Results: 12 clinical studies were selected. These studies were analyzed by author & year, subjects, diagnostic criterion, evaluation criterion, syndrome differentiation, treatment period, methods& results, frequent acupoints and assessment of the quality of studies. All of reports achieved effective therapeutic results on the pediatric tic disorder with Tuina treatment. Conclusion: Tuina treatment has a positive effect and are easily accepted by children who have fear and rejection to traditional Korean Medicine such as acupuncture and Herbal remedy. It is also safe and simple to operate. So the Tuina treatment is worthy to disseminate potential for further development in the treatment of pediatric tic disorders.

• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.141-149
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• 2008

Objective : This study was designed to analyze the herbal medicine case-control studies of tic disorder in traditional chinese medicine. Method : For this study, we searched the studies on tic disorder, which had been published 2007, through web-site CNKI(中國知識基魔設施工程) http://www.cnki.net). There were 15 herbal medicine case-control studies and we focused on those studies. Results: 1. DSM-IV(7 studies), CCMD(5 studies) and ICD-10(3 studies) were frequently used in the diagnosis of tic disorder. 2. Paeonia radix alba, Uncariae ramulus et uncus and Glycyrrhizae radix were frequently used in treatment. Moreover Scorpio, Gastrodiae rhizoma, Pinelliae rhizoma and so on were used. 3. Treatment results were assessed by improvement of symptom, YGTSS and so on. 4. Herbal medicine treatment was more effective than western medicine treatment in most studies, and side effects of herbal medicine were far less than those of western medicine. Conclusion : There have been reported many herbal medicine treatment studies of tic disorder in traditional chinese medicine. We believe that these studies can be applied to the clinical practices in Korean medicine.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.1B
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• pp.21-27
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• 2011

When execute runoff forecasting, can not remove perfectly uncertainty of forecasting results. But, reduce uncertainty by various techniques analysis. This study applied various forecasting techniques for runoff prediction's accuracy elevation in Gongju basin. statics techniques is ESP, Period Average & Moving average, Exponential Smoothing, Winters, Auto regressive moving average process. Authoritativeness estimation with results of runoff forecasting by each techniques used MAE (Mean Absolute Error), RMSE (Root Mean Squared Error), RRMSE (Relative Root Mean Squared Error), Mean Absolute Percentage Error (MAPE), TIC (Theil Inequality Coefficient). Result that use MAE, RMSE, RRMSE, MAPE, TIC and confirm improvement effect of runoff forecasting, ESP techniques than the others displayed the best result.

• Korean Journal of Biological Psychiatry
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• v.13 no.4
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• pp.299-304
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• 2006

Objectives : The purpose of the present study was to investigate whether the TaqI A polymorphism of dopamine receptor D2 gene(DRD2) is associated with Tourette syndrome(TS) and chronic motor tic disorder(CMT) in Korean population. Methods : DRD2 TaqI A RFLP genotyping was carried out with DNA extracted from blood samples of 75 patients with tic disorders(47 with TS and 28 with CMT) and 90 healthy subjects. Genotype and allelic frequencies for the DRD2 gene polymorphisms of the tic disorder group as a whole were compared to those of the control group. Separating the TS group, thereafter, the frequency of genotypes and alleles were compared to those of the controls. Results : The results demonstrated that genotype and allele distributions for the DRD2 gene polymorphism in the tic disorder as a whole, TS, and control groups were not significantly different. Conclusion : No association was found for DRD2 gene, TS and CMT. The data suggest that DRD2 gene may not be a useful marker for the prediction of the susceptibility of tic disorder.

• The Journal of the Korea Contents Association
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• v.22 no.10
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• pp.861-869
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• 2022

In patients with Tourette's syndrome, a tic occurs when Mu wave synchronization is broken. Conversely, when Mu wave synchronization is achieved, a tick does not occur. When the tic is suppressed, the cognitive control response process is changed, and if the neurofeedback training that adjusts the EEG frequency power is performed with the changed, the patient will be treated autonomously without artificially suppressing the tic. The results of the research test suggest that if the tic patient does not artificially synchronize mu waves in the premotor cortex (Frontal Cortical 3 site), and if EEG control is performed autonomously like neurofeedback training, as a result, tics do not occur. Cognitive control response processes are altered when a subject is inhibited from tics. By training the altered cognitive control with neurofeedback that modulates EEG frequency power, the patient can be treated autonomously without artificially suppressing the tic.Mu-wave synchronizationcan now be added to existing neurofeedback treatment protocols such as SMR reinforcement, theta-beta-wave imbalance correction, and alpha-wave reinforcement. This study will be used in follow-up studies and clinical trials to more scientifically verify the neurofeedback treatment protocol, a treatment for patients with Tourette's syndrome.