• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.2
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• pp.300-306
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• 2000

In the present studies, we assessed the stability of active components and toxicological safety of irradiated Angelica gigas Nakai(Danggui). In order to confirm the stability of active components in the ${\gamma}$-irradiated roots of Danggui, the quantitative analysis of decursin and decursinol angelate of ${\gamma}$-irradiated sample was carried out by high performance liquid chromatographic (HPLC) methods using reverse phase columns and normal phase columns. From the root of Danggui, decursin and decursinol angelate were isolated by a silica gel column chromatography(toluene : ether (1 : 1), Hexane : EtOAc(15 : 1)). And then the structures were confirmed in the 1H and 13C-NMR analysis. The HPLC chromatograms of decursin and decursinol angelate in ${\gamma}$-irradiated Danggui were similar with those of non-irradiated sample. In the examination of in vitro genotoxicity of the water extract from ${\gamma}$-irradiated Danggui using Salmonella reversion assay(Ames test) and micronucleus test in Chinese hamster ovary (CHO) cells, mutagenicity was not exhibited in the two assays with or without metabolic activation. These resutls suggest that active components in the ${\gamma}$-irradiated Danggui should be stable and that the safety of ${\gamma}$-irradiated Danggui could be revealed in further test in vivo.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.1
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• pp.1-7
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• 2021

PURPOSE: The purpose of this study is to conduct inter-rater and intra-rater reliability tests in patients with low back pain (LBP) using the prone instability test (PIT) and side-lying instability test (SIT). We have analyzed the Korean version Oswestry disability index (K-ODI) correlations and radiograph finding (RF) for validity. METHODS: Individuals (n = 51) (mean age of 40.27 ± 13.28) with LBP for at least over a week were recruited, together with two participating physical therapist examiners. The measurement consisted of PIT, PST, K-ODI, and RF. Sensitivity (Sn), specificity (Sp), positive predictive value, negative predictive value, prevalence index, agreement %, Cohen's kappa, and prevalence-adjusted bias-adjusted kappa (PABAK) were calculated. The PIT and SIT were compared with RF for validity analysis, while PIT, SIT, K-ODI, and RF were calculated for the correlation analysis. RESULTS: The intra-rater reliability test measured for the PIT (kappa = .79, PABAK = .88) and SIT (kappa = .73, PABAK = .84), and inter-rater reliability test measured for the SIT (kappa = .80, PABAK = .88) showed good agreements. The PIT (Sn = .65, Sp = .63) and SIT validities (Sn = .68, Sp = .70) were compared with RF, showing a significant correlation in PIT and RF (r = .69), SIT and RF (r = .73), and PIT and K-ODI (r = .53). CONCLUSION: The SIT is a more comfortable position test than the PIT in patients. Both PIT and SIT have acceptable reliability and validity.

• Journal of Pharmacopuncture
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• v.26 no.1
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• pp.86-93
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• 2023

Objectives: This study aimed to evaluate the potential toxicity of a recently developed and clinically used No-Pain pharmacopuncture (NPP) solution. We also assessed the lethal dose of the NPP agent following a single intramuscular injection in Sprague-Dawley (SD) rats. Methods: Animals were divided into two groups: the NPP test material group and the normal saline control group. A single intramuscular injection of the NPP agent (1.0 mL/animal) was administered to rats of the NPP test material group. The control group rats received the same volume of normal saline. Both female and male rats were included in each group. All rats were monitored for clinical signs and body weight changes for 14 days after administration of the test substance or saline. At the end of the observation period, a gross necropsy was conducted and localized tolerance at the injection site was analyzed. Results: No mortality was observed in the NPP test material and control groups. Moreover, no test substance-related effects were observed on clinical signs, body weight, necropsy findings, and localized tolerance at the injection site. Conclusion: The approximate lethal dose of the NPP agent is greater than 1.0 mL/animal under the conditions used in this study. Additional toxicity evaluations and clinical studies are needed to confirm the safety of NPP use in clinical practice.

• The Journal of Advanced Prosthodontics
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• v.16 no.1
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• pp.38-47
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• 2024

PURPOSE. This study aims to evaluate the accuracy of different shade selection techniques and determine the matching success of crown restorations fabricated using digital shade selection techniques. MATERIALS AND METHODS. Teeth numbers 11 and 21 were prepared on a typodont model. For the #11 tooth, six different crowns were fabricated with randomly selected colors and set as the target crowns. The following four test groups were established: Group C, where the visual shade selection was performed using the Vita 3D Master Shade Guide and the group served as the control; Group Ph, where the shade selection was performed under the guidance of dental photography; Group S, where the shade selection was performed by measuring the target tooth color using a spectrophotometer; and Group I, where the shade selection was performed by scanning the test specimens and target crowns using an intraoral scanner. Based on the test groups, 24 crowns were fabricated using different shade selection techniques. The ΔE values were calculated according to the CIEDE2000 (2:1:1) formula. The collected data were analyzed by means of a one-way analysis of variance. RESULTS. For the four test groups (Groups C, Ph, S, and I), the following mean ΔE values were obtained: 2.74, 3.62, 2.13, and 3.5, respectively. No significant differences were found among the test groups. CONCLUSION. Although there was no statistically significant difference among the shade selection techniques, Group S had relatively lower ΔE values. Moreover, according to the test results, the spectrophotometer shade selection technique may provide more successful clinical results.

• Journal of the Korea institute for structural maintenance and inspection
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• v.6 no.1
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• pp.223-231
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• 2002

The pilot tests for the development of biaxial failure envelope of high strength concrete of reactor containments were performed. To apply biaxial loads to concrete, the plate specimens were used. The technical difficulties encountered on the development of a suitable biaxial test setup were discussed. To decide the optimum thickness of plate specimen, the nonlinear finite element analyses using ABAQUS were performed for a 1/8 model of cylindrical specimen(${\Phi}150{\times}300$) and four 1/4 models of plate Specimens ($200{\times}200{\times}T$(=30, 50, 60, 70)mm) under uniaxial compression. Analytical values and test data of relative strength ratio between those specimens with different geometric shapes were also compared. The various test data were obtained under uniaxial compression, uniaxial tension, and biaxial compression and then the stress-strain responses were plotted. The test data indicated that the strength of concrete under biaxial compression, $f_1/f_2=-1/-1$, is 15 percent larger than that under uniaxial compression and the poisson's ratio of concrete is 0.16. Teflon pads employed to eliminate friction between test specimen and loading platens showed an excellent effect under biaxial compression.

• Parasites, Hosts and Diseases
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• v.25 no.1
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• pp.7-12
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• 1987

The indirect fluorescent antibody(IFA) test was used to detect serum IgG and IgM antibodies to Trichomonas vaginalis in 31 vaginal trichomoniasis, 7 candidiasis and in 20 non-infected healthy women with antigen prepared from axonic culture of Trichomenas vaginalis isolated from vulvovaginitis patient. The results were as follows: 1. In 31 vaginal trichomoniasis the positive reactions of IgG antibody were 27 in the 1/8 dilution or higher and :l in the 1/4 dilution whereas in healthy women the reaction showed significantly low as in the 1/4 dilution or below. 2. The sensitivity and specificity of IFA test for IgG antibody to trichomonad antigen in this study were 87.1% and 100%, respectively. 3. No significant difference of IgM antibody levels between vaginal trichomoniasis and healthy women was observed. 4. No relation between the levels of IgG and IsM antibodies to trichomonad antigen by IFA test was observed. 5. No relation between the time lapse and the level of serum IgG antibodies in IFA test of vaginal trichomoniasis was regarded. In conclusion the present study suggests that IFA test in trichomoniasis could be a useful tool for detection of anti-trichomonad IgG antibodies and applicable as an immunodiagnostic method.

• Journal of National Security and Military Science
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• s.8
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• pp.383-420
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• 2010

This article is focusing on the improvement of weapon system test & evaluation, aimed at the weapon system in the research development stage. This article suggests improvement directions in three aspects(organization and system, skilled manpower and technology, test facilities of weapon system test & evaluation) as follows. 1) Weapon system test & evaluation organization and system a. Establishment of comprehensive test & evaluation system b. Making regulation for comprehensive test infrastructure management. c. Standardization of test & evaluation process, which can be used in special subject to army, navy and air force. 2) Skilled manpower and technology of weapon system test & evaluation a. Training & education, management of test & evaluation experts. b. Establishment of skill management system of test & evaluation. 3) Test facilities of weapon system test & evaluation a. Establishment of comprehensive improvement direction of test & evaluation installation and equipment. b. Consideration of counter measures to prevent overlapping investment, and to use the test & evaluation resources efficiently. c. Establishment of organic network for the effective use of test & evaluation installation and equipment. d. Establishment of detailed cooperation plan for the commonage of test & evaluation facility and equipment.

• Journal of the Korean Society of Industry Convergence
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• v.17 no.1
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• pp.7-14
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• 2014

In this study, characteristic of elastic paving materials in bicycle road using polyurethane were studied experimentally. As a results, following their good result was obtained. Bicycle road packaging materials are flexural strength g test, ratio of mass change after freezing and thawing, repulsion elasticity test, water Permeation coefficient test and slip resistance test results showed good performance.

• Proceedings of the Korea Concrete Institute Conference
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• 2002.10a
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• pp.353-358
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• 2002

The purpose of this paper was to estimate the cumulative damage of pavement concrete by split tension fatigue test. The split tension fatigue test of variable amplitude loading were performed in two and three stages. The results of the fatigue test by variable amplitude loading showed that the sums of damage were greater than 1 in the increasing sequence loading tests, and less than 1 in the decreasing sequence loading tests. The remaining life estimated by equivalent damage theory was almost similar to that of experimental results.

• 한국데이터정보과학회:학술대회논문집
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• 2005.10a
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• pp.135-138
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• 2005

In this paper, we consider the problem of testing for parameter change in time series models based on a cusum of squares. Although the test procedure is well-established for the mean and variance in time series models, a general parameter case was not discussed in literatures. Therefore, here we develop the cusum of squares type test for parameter change in a more general framework. As an example, we consider the change of the parameters in an RCA(1) model. Simulation results are reported for illustration.