• Journal of Yeungnam Medical Science
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• 제5권2호
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• pp.171-174
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• 1988

Tc99-IDAs를 이용하여 원발성 간세포암뿐만 아니라 폐에 전이된 간세포암까지 확인할 수 있다는 보고가 있었기에 저자들은 원발성 간세포암에서 폐전이가 의심되는 환자에게 Tc99m-DISIDA를 이용하여 간 및 폐를 주사하여 흉부 X-선상의 폐전이와 일치하는 주사상의 열소를 확인하였으며 이는 우리나라에 많은 간세포암의 진단과 수술전 전이유무의 평가 및 치료설정에 도움이 될 수 있을 것으로 생각되어 보고하고자 한다.

• 대기
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• 제18권1호
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• pp.43-53
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• 2008

A new proposition on the definition of the tropical cyclone (TC) which influences the Korean Peninsula (KP) is presented. The definition is based upon the TC track and intensity, 34 wind swath considering the TC size, and the line of 200 nautical mile (NM) from the KP shore which is the boundary of the official warning of Korea Meteorological Administration. Four types are proposed. First type is TC that hits the KP inland. Second is TC that falls within the 200-NM boundary. Third type is TC that passes outside the 200-NM boundary but large enough to significantly influence the KP. Last, the cases for a TC which are downgraded to the midlatitude cyclone and hit the KP are included. 30-year reanalysis reveals that 21 tropical cyclones should be included in the TC list that influenced the KP during the period from 1977 to 2006, which corresponds to 3.93 TCs per year. Among them, number of type I, II, III and IV TCs turn are to be 36, 47, 10, and 16, respectively. The net increase found in the current reanalysis is 2, 5, 7, and 7 for each type.

• Journal of Yeungnam Medical Science
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• 제37권3호
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• pp.217-225
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• 2020

Background: This study was performed to provide a long-term bacterial seal through the formation of reparative dentin bridge, calcium silicate-based pulp capping materials have been used at sites of pulpal exposure. The aim of this study was to evaluate the mineralization-inducing potentials of calcium silicate-based pulp capping materials (ProRoot MTA [PR], Biodentine [BD], and TheraCal LC [TC]) in human dental pulp cells (HDPCs). Methods: Specimens of test materials were placed in deionized water for various incubation times to measure the pH variation and the concentration of calcium released. The morphology of HDPCs cultured on the specimens was examined using a confocal laser scanning microscope (CLSM). Alizarin red S staining and alkaline phosphatase assays were used to evaluate mineralization-inducing potentials of the capping materials. Results: BD showed the highest calcium release in all test periods, followed by PR and TC. (p<0.05). All experimental groups showed high alkalinity after 1 day, except at 14 days. BD showed the highest cell viability compared with PR and TC after 1 and 3 days, while TC showed the lowest value (p<0.05). The CLSM analysis showed that cells were well adhered and expressed actin filaments for all pulp capping materials. Mineralization by PR and BD groups was higher than that by TC group based on alizarin red S staining. BD showed significantly higher alkaline phosphatase activity than PR and TC, while TC showed the lowest value (p<0.05). Conclusion: Within the limitations of the in vitro study, BD had higher mineralization-inducing potential than PR and TC.

• 한국물환경학회지
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• 제23권1호
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• pp.12-18
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• 2007

Difference of total coliforms (TC) survival time of mixed samples (effluent were mixed by seawater or freshwater) were examined in various conditions. The time taken to achieve a 90% reduction in the TC concentration ($T_{90}$) of effluent, high initial TC concentration and low initial TC concentration samples indicated 143.9, 121.9 and 89.6 hours at $25^{\circ}C$, respectively. At $4^{\circ}C$, log removal rate after 336 hours were 0.96, 1.04, and 1.30. TC survival time of effluent-inoculated seawater sample was longer than that of effluent-inoculated freshwater sample in laboratory. At outdoor condition, TC inactivation curves of effluent-inoculated seawater or freshwater samples showed similar patterns. And both of them were greatly influenced by climate condition. There was not enough evidence that TC survived longer in freshwater than sea water. It was unlikely that the salinity of sea water contributed to the inactivation process of TC.

• 대한핵의학회지
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• 제31권3호
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• pp.395-398
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• 1997

갈색 종양 (brown tumor or osteitis cystica fibrosa)은 일차성 또는 이차성 부갑상선 기능항진증의 골소견 중 하나이다. 부갑상선 질환이 의심될 때에 과거에는 $^{201}TI/^{99m}Tc$ 감영 스캔이 가장 많이 이용되는 비침습적 방법 중 하나였으나, 근래에는 $^{99m}Tc-MIBI$를 이용한 핵의학 영상이 더 널리 사용되고 있다. $^{99m}Tc-MIBI$의 종양 섭취에는 혈류의 증가, 세포 대사 및 미토콘드리아의 활동성이 관계된다고 보고되었지만, 갈색 종양에의 $^{99m}Tc-MIBI$의 섭취기전에 대해서는 거의 알려져 있지 않다. 저자들은 이전에 중족골의 거대 세포종 (Giant cell tumor)으로 오진하였던 환자에서, $^{99m}Tc-MIBI$스캔상 갈색 종양이 의심되었고, 후에 수술을 통해 부갑상선 암종 (Parathyroid carcinoma)이 확인되었던 1예를 보고하고자 한다.

• 한국자기학회지
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• 제9권5호
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• pp.223-226
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• 1999

Pd(001) 위에 올려진 Tc 0.5(Half-monolayer) 웃층의 자성상태와 전자구조를 FLAPW(Full-Potential Linearized Augmented Plane Wave) 에너지 띠 방법을 이용하여 이론적으로 연구하였다. Tc 웃층의 안정된 자성상태를 알아보기 위해 상자성 상태와 강자성 상태의 총에너지를 계산하였다. 계산결과 Tc 0.5 웃층은 강자성 상태가 상자성 상태보다 에너지적으로 안정하였고 그 자기 모멘트는 2.09 $\mu$B이었다. 0.5층 Tc/Pd(001)에 대한 머핀-핀(MT) 구 내의 전자수와 상태밀도 등의 전자구조 계산결과를 제시하고 논의 검토하였다.

• Molecules and Cells
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• 제26권4호
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• pp.387-395
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• 2008

A novel Tc1-like transposable element has been identified as a new DNA transposon in the mud loach, Misgurnus mizolepis. The M. mizolepis Tc1-like transposon (MMTS) is comprised of inverted terminal repeats and a single gene that codes Tc1-like transposase. The deduced amino acid sequence of the transposase-encoding region of MMTS transposon contains motifs including DDE motif, which was previously recognized in other Tc1-like transposons. However, putative MMTS transposase has only 34-37% identity with well-known Tc1, PPTN, and S elements at the amino acid level. In dot-hybridization analysis used to measure the copy numbers of the MMTS transposon in genomes of the mud loach, it was shown that the MMTS transposon is present at about $3.36{\times}10^4$ copies per $2{\times}10^9$ bp, and accounts for approximately 0.027% of the mud loach genome. Here, we also describe novel MMTS-like transposons from the genomes of carp-like fishes, flatfish species, and cichlid fishes, which bear conserved inverted repeats flanking an apparently intact transposase gene. Additionally, BLAST searches and phylogenetic analysis indicated that MMTS-like transposons evolved uniquely in fishes, and comprise a new subfamily of Tc1-like transposons, with only modest similarity to Drosophila melanogaster (foldback element FB4, HB2, HB1), Xenopus laevis, Xenopus tropicalis, and Anopheles gambiae (Frisky).

• 한국표면공학회지
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• 제56권1호
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• pp.40-54
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• 2023

In this work, we synthesized a novel electrochemical sensing materials based on tetracarboxylic copper phthalocyanine (TcCuPtc) conjugated PANI (TcCuPtc@PANI). The synthesized materials were employed to modify the screen-printed carbon electrode (SPCE) for the selective sensing of 4-nitrophenol. The TcCuPtc was conjugated with conducting polymer of PANI through the electrostatic interaction and π-π electron conjugation, the polymer film of PANI to inhibit the leakage of TcCuPtc from the surface of the electrode. The prepared TcCuPtc@PANI were characterized and confirmed by scanning electron microscopy (SEM) with EDX, ATR-IR, UV-vis absorption spectroscopy, cyclic voltammetry, and differential pulse voltammetry techniques. The prepared TcCuPtc@PANI/SPCE showed an excellent electrocatalytic sensing of 4-NP in the linear concentrations from 3 to 500 nM with a LOD of 0.03 nM and a sensitivity of 8.8294 ㎂/nM cm^-2. However, the prepared TcCuPtc@PANI/SPCE showed selective sensing of 4-NP in the presence of other interfering species. The practical applicability of the TcCuPtc@PANI/SPCE was employed for the sensing of 4-NP in different water samples by standard addition method and showed satisfactory recovery results.

• 대한핵의학회지
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• 제27권2호
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• pp.270-276
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• 1993

$Technetium-^{99m}$ labeling method using bifunctional chelating agent cyclic DTPA has been evaluated with human polyclonal nonspecific IgG. IgG was conjugated with cyclic DTPA with various molar ratio. Reduction of $^{99m}Tc$ was done with $Na_2S_2O_4$ with various molar excess. Labeling efficiency and identification of polymer was confirmed with HPLC using TSK4000 SW column. Polymer was purified with 100 cm Sepharose 6LB column. Cultured $1{\times}10^9$ Staphylococcus aureus were injected into rat thigh 24 hours later labeled IgG was injected, and in vivo distribution was observed 4 and 24 hours thereafter. Reduction of $^{99m}Tc$ was optimal with the 10000-50000 times molar excess of $Na_2S_2O_4$. Polymer formation increased with increasing mloar excess of cyclic DTPA to IgG. Three step labeling-labeling DTPA conjugated IgG after reduction of $^{99m}Tc$-made more polymer than two two step labeling-simultaneous mixing DTPA conjugated IgG, $^{99m}Tc$ and $Na_2S_2O_4$. $^{99m}Tc$ blood clearance and lower uptake in the abscess and other organs. IgG conjugated with 200 times molar excess of cyclic DTPA showed slower blood clearance with 200 times molar excess of cyclic DTPA showed slower blood clearance than that of 200 times molar excess of cyclic DTPA showed slower blood clearance than that of 20 times molar excess. In the $^{99m}Tc$ labeling of IgG with cyclic DTPA for the immunoscintigraphy, obtimal labeling condition should be chosen, and effect of the $^{99m}Tc$ labeled IgG polymer should be considered.

• 한국의학물리학회지:의학물리
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• 제19권1호
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• pp.1-8
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• 2008

테크니슘$(^{99m}Tc)$은 현재 핵의학 분야에서 진단용 방사선원으로 가장 널리 쓰이고 있는 방사성 동위원소 중 하나이다. 일반적으로 테크니슘은 $^{99m}Tc$ Generator라 불리는 장치 안에서 모핵종인 $^{99}Mo$의 붕괴를 통해 생산되는데, $^{99}Mo$과 $^{99m}Tc$에서 비교적 높은 방사선을 방출하기 때문에 이를 차폐하기 위하여 주로 납으로 제작되어 있다. 본 논문에서는 국내에서 비교적 사용 빈도가 높고 교정 방사능이 500 mCi인 일본 제품을 대상으로, 최대 방사능량 적제조건에서 차폐용기 표면으로부터 10 cm, 100 cm에서 각각 2.0 mSv/h, 0.02 mSv/h를 초과하지 않아야 한다는 국내 법적 제한치를 만족시키는지 여부를 GEANT4를 이용하여 시뮬레이션하였다. 계산 결과 용기 밖으로 방출되는 방사선량이 법적 기준치를 초과하지 않는 것으로 나타났다.