• 제목/요약/키워드: TAL

검색결과 133건 처리시간 0.032초

Pharmacokinetics of thalidomide in dogs: can feeding affect it? A preliminary study

  • Pierini, Alessio;Sartini, Irene;Giorgi, Mario;Lebkowska-Wieruszewska, Beata;Lisowski, Andrzej;Poapolathep, Amnart;Marchetti, Veronica
    • Journal of Veterinary Science
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    • 제21권5호
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    • pp.60.1-60.11
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    • 2020
  • Background: Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. Objectives: The aim of the study was to assess the pharmacokinetics of TAL after single oral administration in dogs. Additionally, the influence of feeding on the pharmacokinetic profile of TAL in dogs has been preliminarily investigated. Methods: Six healthy adult female Labradors were enrolled according to a randomized single-dose, 2-treatment, 2-phase, paired 2 × 2 cross-over study design. The dogs were administered a single 400 mg capsule of TAL in fasted and fed conditions. Blood was collected from 15 min to 48 h after dosing, and TAL quantified in plasma by a validated high-performance liquid chromatography method. The pharmacokinetics of TAL were analyzed using a non-compartmental approach. Results: TAL concentration was quantifiable up to 10 h and 24 h after fasted and fed conditions, respectively. Cmax (fasted, 1.34 ± 0.12 ㎍/mL; fed, 2.47 ± 0.19 ㎍/mL) and Tmax (fasted, 3 h; fed, 10 h) differed substantially between the 2 groups. AUC and t1/2λz were significantly higher in fed (42.46 ± 6.64 mg × h/L; 17.14 ± 4.68 h) compared to fasted (12.38 ± 1.13 mg × h/L; 6.55 ± 1.25 h) dogs. The relative oral bioavailability of TAL for the fasted group was low (36.92% ± 3.28%). Conclusions: Feeding affects the pharmacokinetics of oral TAL in dogs, showing a delayed, but higher absorption with different rate of elimination. These findings are of importance in clinical veterinary settings, and represent a starting point for further related studies.

한국 탈의 조형미(造形美)를 활용한 호텔 유니폼 디자인 연구(硏究) (A Study on the Hotel Uniform Design Applying Visual Image of the Traditional Korean Mask)

  • 주성희
    • 한국의상디자인학회지
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    • 제15권3호
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    • pp.167-185
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    • 2013
  • Among korean traditional culture, TalChum(mask dance) which bears our unique cultural emotion, is about wearing a Tal(korean mask) and dancing, which express our ethnic feeling. The ethnic feeling was expressed into silhouette of hotel uniform which sightseers at home and abroad most frequently visit. This would be the best and the fastest way to show and deliver ethinic feeling of Korea. Fashion design of an uniform would be the best way to express group's unification and attachment. The purpose of this study was to design uniforms, in order to satisfy the property of function, aesthetic points, symbolism to inhere and to differentiate the group from others by using plastic and creative design. This study was meant to induce people to get near to characteristic of Korean culture, using hotel uniform design. Mask's plastic beauty of characteristic Chosun dynasty and express vividly Tal's image with Korean traditional reality was applied on hotel uniform design. By doing so, visitors can come back to the hotel with longtime memory of Korea. The characteristics and the humorous symbolism of Tal were designed and applied to uniform design on collar, bodice, pocket, and sleeves.

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역대(歷代) 의서(醫書)에서 탈영실정(脫營失精)의 의미(意味) 변화(變化) (Conceptual Variation of TalYeong-SilJeong in the Medical History)

  • 홍세영;이재혁
    • 동의신경정신과학회지
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    • 제25권2호
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    • pp.203-212
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    • 2014
  • Objectives: The aim of this study is to bring new light on TalYeong-SilJeong (exhaustion of Yeonggi and loss of Essence) through the verification of both the original intention of Hwangjenaegyeong and the conceptual variation afterwards. Methods: Of various East Asian medical texts, those inferring to TalYeong-SilJeong includeing Hwangjenaegyeong itself were closely examined under the aspect of its conception. Results: TalYeong-SilJeong was suggested as the first representative tool and accurate diagnostic method of questioning in order to determine the mental state of a patient. However, medical scholars have suggested different levels of meaning. Some used the term for the broad coverage of mental illnesses, understanding Hwangjenaegyeong's discrimination as symbolic gesture, while others projected an unchallenged value on it and weaved it into the concrete set of a disease. Conclusions: The treatment of TalYeong-SilJeong is suggested according to the varying viewpoints of each medical text. By understanding multiple layers of the conception beyond, a clinician is expected to gain an exuberant image of conception on the one hand and an insight for more effective treatment on the other hand.

우리나라 재배콩(Glycin max L.)서 Sinorhizobium fredii의 공생효과(共生效果)와 근류형성경합력(根瘤形成競合力) (Symbiotic Effectiveness and Competitiveness of Sinorhizobium fredii on Korean soybeans (Glycin max L.))

  • 강위금;정연태;강항원;류진창;이상규;하호성
    • 한국토양비료학회지
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    • 제30권3호
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    • pp.288-294
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    • 1997
  • 콩 재배시(栽培時) 조속생육형(早速生育型)인 Sinorhizobium fredii의 접종제(接種劑) 이용가능성(利用可能性)을 검토코자 TAL 1781 등 9종의 S. fredii를 우리나라 재배콩 11품종(品種)에 접종시험(接種試驗)한 결과는 다음과 같았다. 시험(試驗)된 S. fredii는 모두가 광교에서 근류형성력(根瘤形成力)을 보였으나 단엽콩에서는 근류(根瘤)를 형성하지 못하였다. S. fredii TAL 1781과 TAL 1840, TAL 1899의 콩 건물생산량(乾物生産量)은 B. Japonicum YCK 213 및 USDA 110에 비해서 평균 53% 수준(水準)이었으며, S. fredii 균주(菌株) 중에서는 TAL 1781이 가장 우수하였다. 그리고 S. fredii는 B. japonicum USDA 110과 혼합접종(混合接種)했을 때 보다 YCK 213과 혼합접종(混合接種)했을 때에 더 많은 건물생산력(乾物生産力)을 보였다. S. fredii의 B. japonicum 대비(對比) 근류점유율(根瘤占有率)은 B. japonicum YCK 213과 혼합접종(混合接種)했을 때(8.3~26.7%) 보다 B. japonicum USDA 110과 혼합접종(混合接種)했을 때(10.0~30.0%) 더 높았다. 그러므로 S. fredii는 콩 건물생산력(乾物生産力) 및 근류형성(根瘤形成) 경합력(競合力) 면에서 B. japonicum보다 불량한 접종반응(接種反應)을 보여 콩의 근류균접종제(根瘤菌接種劑)로서의 실용성(實用性)이 낮음을 알 수 있었다.

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논벼 장.단간품종의 증발산제계수와 건물량과의 관계에 대한 연구(I) (Studies on Relations between Various Coeffcients of Evapo-Transpiration and Quantities of Dry Matters for Tall-and Short Statured Varieties of Paddy Rice)

  • 류한열;김철기
    • 한국농공학회지
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    • 제16권2호
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    • pp.3361-3394
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    • 1974
  • The purpose of this thesis is to disclose some characteristics of water consumption in relation to the quantities of dry matters through the growing period for two statured varieties of paddy rice which are a tall statured variety and a short one, including the water consumption during seedling period, and to find out the various coefficients of evapotranspiration that are applicable for the water use of an expected yield of the two varieties. PAL-TAL, a tall statured variety, and TONG-lL, a short statured variety were chosen for this investigation. Experiments were performed in two consecutive periods, a seedling period and a paddy field period, In the investigation of seedling period, rectangular galvanized iron evapotranspirometers (91cm${\times}$85cm${\times}$65cm) were set up in a way of two levels (PAL-TAL and TONG-lL varieties) with two replications. A standard fertilization method was applied to all plots. In the experiment of paddy field period, evapotanspiration and evaporation were measured separately. For PAL-TAL variety, the evapotranspiration measurements of 43 plots of rectangular galvanized iron evapotranspirometer (91cm${\times}$85cm${\times}$65cm) and the evaporation measurements of 25 plots of rectangular galvanized iron evaporimeter (91cm${\times}$85cm${\times}$15cm) have been taken for seven years (1966 through 1972), and for TONG-IL variety, the evapotranspiration measurements of 19 plots and the evaporation measurements of 12 plots have been collected for two years (1971 through 1972) with five different fertilization levels. The results obtained from this investigation are summarized as follows: 1. Seedling period 1) The pan evaporation and evapotranspiration during seedling period were proved to have a highly significant correlation to solar radiation, sun shine hours and relative humidity. But they had no significant correlation to average temperature, wind velocity and atmospheric pressure, and were appeared to be negatively correlative to average temperature and wind velocity, and positively correlative to the atmospheric pressure, in a certain period. There was the highest significant correlation between the evapotranspiration and the pan evaporation, beyond all other meteorological factors considered. 2) The evapotranpiration and its coefficient for PAL-TAL variety were 194.5mm and 0.94∼1.21(1.05 in average) respectively, while those for TONG-lL variety were 182.8mm and 0.90∼1.10(0.99 in average) respectively. This indicates that the evapotranspiration for TONG-IL variety was 6.2% less than that for PAL-TAL variety during a seedling period. 3) The evapotranspiration ratio (the ratio of the evapotranspiration to the weight of dry matters) during the seedling period was 599 in average for PAL-TAL variety and 643 for TONG-IL variety. Therefore the ratio for TONG-IL was larger by 44 than that for PAL-TAL variety. 4) The K-values of Blaney and Criddle formula for PAL-TAL variety were 0.78∼1.06 (0.92 in average) and for TONG-lL variety 0.75∼0.97 (0.86 in average). 5) The evapotranspiration coefficient and the K-value of B1aney and Criddle formular for both PAL-TAL and TONG-lL varieties showed a tendency to be increasing, but the evapotranspiration ratio decreasing, with the increase in the weight of dry matters. 2. Paddy field period 1) Correlation between the pan evaporation and the meteorological factors and that between the evapotranspiration and the meteorological factors during paddy field period were almost same as that in case of the seedling period (Ref. to table IV-4 and table IV-5). 2) The plant height, in the same level of the weight of dry matters, for PAL-TAL variety was much larger than that for TONG-IL variety, and also the number of tillers per hill for PAL-TAL variety showed a trend to be larger than that for TONG-IL variety from about 40 days after transplanting. 3) Although there was a tendency that peak of leaf-area-index for TONG-IL variety was a little retarded than that for PAL-TAL variety, it appeared about 60∼80 days after transplanting. The peaks of the evapotranspiration coefficient and the weight of dry matters at each growth stage were overlapped at about the same time and especially in the later stage of growth, the leaf-area-index, the evapotranspiration coefficient and the weight of dry matters for TONG-IL variety showed a tendency to be larger then those for PAL-TAL variety. 4) The evaporation coefficient at each growth stage for TONG-IL and PAL-TALvarieties was decreased and increased with the increase and decrease in the leaf-area-index, and the evaporation coefficient of TONG-IL variety had a little larger value than that of PAL-TAL variety. 5) Meteorological factors (especially pan evaporation) had a considerable influence to the evapotranspiration, the evaporation and the transpiration. Under the same meteorological conditions, the evapotranspiration (ET) showed a increasing logarithmic function of the weight of dry matters (x), while the evaporation (EV) a decreasing logarithmic function of the weight of dry matters; 800kg/10a x 2000kg/10a, ET=al+bl logl0x (bl>0) EV=a2+b2 log10x (a2>0 b2<0) At the base of the weight of total dry matters, the evapotranspiration and the evaporation for TONG-IL variety were larger as much as 0.3∼2.5% and 7.5∼8.3% respectively than those of PAL-TAL variety, while the transpiration for PAL-TAL variety was larger as much as 1.9∼2.4% than that for TONG-IL variety on the contrary. At the base of the weight of rough rices the evapotranspiration and the transpiration for TONG-IL variety were less as much as 3.5% and 8.l∼16.9% respectively than those for PAL-TAL variety and the evaporation for TONG-IL was much larger by 11.6∼14.8% than that for PAL-TAL variety. 6) The evapotranspiration coefficient, the evaporation coefficient and the transpiration coefficient and the transpiration coefficient were affected by the weight of dry matters much more than by the meteorological conditions. The evapotranspiratioa coefficient (ETC) and the evaporation coefficient (EVC) can be related to the weight of dry matters (x) by the following equations: 800kg/10a x 2000kg/10a, ETC=a3+b3 logl0x (b3>0) EVC=a4+b4 log10x (a4>0, b4>0) At the base of the weights of dry matters, 800kg/10a∼2000kg/10a, the evapotranspiration coefficients for TONG-IL variety were 0.968∼1.474 and those for PAL-TAL variety, 0.939∼1.470, the evaporation coefficients for TONG-IL variety were 0.504∼0.331 and those for PAL-TAL variety, 0.469∼0.308, and the transpiration coefficients for TONG-IL variety were 0.464∼1.143 and those for PAL-TAL variety, 0.470∼1.162. 7) The evapotranspiration ratio, the evaporation ratio (the ratio of the evaporation to the weight of dry matters) and the transpiration ratio were highly affected by the meteorological conditions. And under the same meteorological condition, both the evapotranspiration ratio (ETR) and the evaporation ratio (EVR) showed to be a decreasing logarithmic function of the weight of dry matters (x) as follows: 800kg/10a x 2000kg/10a, ETR=a5+b5 logl0x (a5>0, b5<0) EVR=a6+b6 log10x (a6>0 b6<0) In comparison between TONG-IL and PAL-TAL varieties, at the base of the pan evaporation of 343mm and the weight of dry matters of 800∼2000kg/10a, the evapotranspiration ratios for TONG-IL variety were 413∼247, while those for PAL-TAL variety, 404∼250, the evaporation ratios for TONG-IL variety were 197∼38 while those for PAL-TAL variety, 182∼34, and the transpiration ratios for TONG-IL variety were 216∼209 while those for PAL-TAL variety, 222∼216 (Ref. to table IV-23, table IV-25 and table IV-26) 8) The accumulative values of evapotranspiration intensity and transpiration intensity for both PAL-TAL and TONG-IL varieties were almost constant in every climatic year without the affection of the weight of dry matters. Furthermore the evapotranspiration intensity appeared to have more stable at each growth stage. The peaks of the evapotranspiration intensity and transpiration intensity, for both TONG-IL and PAL-TAL varieties, appeared about 60∼70 days after transplanting, and the peak value of the former was 128.8${\pm}$0.7, for TONG-IL variety while that for PAL-TAL variety, 122.8${\pm}$0.3, and the peak value of the latter was 152.2${\pm}$1.0 for TONG-IL variety while that for PAL-TAL variety, 152.7${\pm}$1.9 (Ref.to table IV-27 and table IV-28) 9) The K-value in Blaney & Criddle formula was changed considerably by the meteorological condition (pan evaporation) and related to be a increasing logarithmic function of the weight of dry matters (x) for both PAL-TAL and TONG-L varieties as follows; 800kg/10a x 2000kg/10a, K=a7+b7 logl0x (b7>0) The K-value for TONG-IL variety was a little larger than that for PAL-TAL variety. 10) The peak values of the evapotranspiration coefficient and k-value at each growth stage for both TONG-IL and PAL-TAL varieties showed up about 60∼70 days after transplanting. The peak values of the former at the base of the weights of total dry matters, 800∼2000kg/10a, were 1.14∼1.82 for TONG-IL variety and 1.12∼1.80, for PAL-TAL variety, and at the base of the weights of rough rices, 400∼1000 kg/10a, were 1.11∼1.79 for TONG-IL variety and 1.17∼1.85 for PAL-TAL variety. The peak values of the latter, at the base of the weights of total dry matters, 800∼2000kg/10a, were 0.83∼1.39 for TONG-IL variety and 0.86∼1.36 for PAL-TAL variety and at the base of the weights of rough rices, 400∼1000kg/10a, 0.85∼1.38 for TONG-IL variety and 0.87∼1.40 for PAL-TAL variety (Ref. to table IV-18 and table IV-32) 11) The reasonable and practicable methods that are applicable for calculating the evapotranspiration of paddy rice in our country are to be followed the following priority a) Using the evapotranspiration coefficients based on an expected yield (Ref. to table IV-13 and table IV-18 or Fig. IV-13). b) Making use of the combination method of seasonal evapotranspiration coefficient and evapotranspiration intensity (Ref. to table IV-13 and table IV-27) c) Adopting the combination method of evapotranspiration ratio and evapotranspiration intensity, under the conditions of paddy field having a higher level of expected yield (Ref. to table IV-23 and table IV-27). d) Applying the k-values calculated by Blaney-Criddle formula. only within the limits of the drought year having the pan evaporation of about 450mm during paddy field period as the design year (Ref. to table IV-32 or Fig. IV-22).

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우지로부터 합성된 바이오 디젤의 포화도 감소를 위한 용매 분별 연구 (Reduction of Saturated Fatty Acid Methyl Esters of Biodiesel Produced from Beef Tallow by Acetone Fractionation)

  • 장화;신정아;이기택
    • 한국응용과학기술학회지
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    • 제28권4호
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    • pp.472-481
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    • 2011
  • It is known that the content of saturated fatty acids methyl ester (SFAME) affect the pour point of biodiesel at low temperature. In this study, biodiesel (BD) was produced from beef tallow (TAL) by alkali catalyst. To reduce the saturation in BD, acetone fractionation was applied. Besides, TAL was also solvent-fractionated to reduce the saturated fatty acid (SFA) content for further producing BD. With acetone, TAL or TAL methyl ester (5:1 v/w) were fractionated at 10, 0, -10, and $-15^{\circ}C$, respectively. At $-10^{\circ}C$, 17.35% of SFA was observed in fractionated TAL (liquid part, -10TAL) when 5:1 solvent ratio was used for 24 hr. Under the same condition, fractionated BD (liquid part, -10BD) showed SFA (33.14%) with 78wt % yield. Also, fractionation of BD with different concentration of crystallizer 209 (0.1, 0.5, and 1%) along with different time (2, 6, 12, and 24 hr.) was observed. The best condition for reducing the SFA was 0.5% of crystallizer 209 addition for 12 hr of fractionation time at $-10^{\circ}C$, in which 30.14% of SFA content was observed in BD (liquid part). Among different crystallizer, ps 66 showed the least content of SFA content (23.28%) in BD after fractionation ($-10^{\circ}C$ and 24 hr) with 0.5wt% addition.

다양한 지방원의 급여가 육계의 생산성, 도체특성, 분내 미생물 조성 및 혈액특성에 미치는 영향 (The Effects of Various Fat Source Feeding on Growth Performance, Carcass Characteristics, Fecal Microflora and Blood Profiles in Broilers)

  • 조진호;곽용철;이장형;노환국;김인호
    • 현장농수산연구지
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    • 제16권1호
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    • pp.93-103
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    • 2014
  • 본 연구는 급이 지방원의 차이가 육계의 생산성, 도체특성, 혈액특성 및 분내 미생물 조성에 미치는 영향을 알아보기 위해 시험을 실시하였다. 사양 시험은 1일령 ROSS 308 768수로 공시하였고, 시험 개시 체중은 39.68 ± 0.14 g으로 32일간 실시하였다. 시험 설계는 1) SBO, basal diet + soybean oil, 2) PF, basal diet + poultry fat, 3) TAL, basal diet + tallow 및 4) LARD, basal diet + lard로 4개 처리구로 나누고 처리당 12반복, 반복당 16수씩 완전 임의 배치하였다. 1-14일령의 생산성에 있어서는 증체량에서 TAL 처리구가 PF 및 LARD 처리구보다 유의적으로 높게 나타났고, 사료섭취량에서 TAL 처리구가 SBO, PF 및 LARD 처리구보다 유의적으로 높게 나타났다. 또한 전체 시험기간동안의 증체량에서 SBO 및 TAL 처리구가 LSRD 처리구보다 유의적으로 높게 나타났다. 혈중 LDL cholesterol 함량은 우지 처리구가 돈지 처리구보다 유의적으로 높게 나타났다. 도체 특성은 가슴육의 적색도에서 PF 및 TAL 처리구가 LARD 처리구보다 유의적으로 낮았다. 그러나 명도 및 황색도에 있어서는 처리구간 유의적인 차이를 나타내지 않았고, 장기 무게에 있어서 또한, 처리구간 유의적인 차이를 나타내지 않았다. 분내 미생물 조성에서도 Lactobacillus 및 Escherichia coli에서 처리구간 유의적인 차이를 나타내지 않았다. 혈중 LDL cholesterol 함량에 있어서 TAL 처리구가 LARD 처리구보다 유의적으로 높게 나타났다. 그러나 혈중 AST, total triglycerides 및 HDL cholesterol 함량에 있어서는 처리구 간 유의적인 차이를 나타내지 않았다. 이상의 결과로부터, 본 시험에서는 육계 사료내 대두유 및 우지 첨가시 증체량을 향상 시키고, 또한 우지 급여시 가슴육의 적색도를 유의적으로 낮춰 주고, 혈중 LDL cholesterol 함량이 증가하는 결과를 나타낸다. 따라서 육계 사료내 식물성 지방원인 대두유 첨가가 증체량을 개선시켜 주고, 혈중 LDL cholesterol이 낮아지는 결과를 가져오는 것으로 판단된다.

Rhizobium meliloti TAL1372에서 섬유소분해효소 유전자 클로닝 (Clonig of CM-cellulase Gene of Rhizobium meliloti TAL1372 in Escherichia coli)

  • 박용우;임선택;강규영;윤한대
    • Applied Biological Chemistry
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    • 제38권4호
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    • pp.313-319
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    • 1995
  • 본 실험은 알팔파(Medicago sativa) 근류균인 Rhizobium meliloti TAL1372 균주에서 섬유소분해효소의 활성을 확인하고 이 유전자를 크로닝하기 위해 코스미드 벡타인 pLAFR3를 사용하여 유전자 은행을 만들었다. 이 유전자 은행으로 부터 분리한 1,000개의 형질 도입체에서 CM-cellulase(carboxymethylcellulase) 활성이 있는 클론(pRC8-71) 하나를 분리하였으며 30kb 크기의 R. meliloti DNA 단편을 함유하고 있는 것을 확인하였다. 이 CM-cellulase 유전자의 발현 산물을 native PAGE 법에 의하여 분자량을 측정한 결과 약 45kD 정도의 크기로 추정되었으며 pRC8-71로 부터 Tn5 변이법에 의해 조사한 결과 30kb 단편 내에서 CM-cellulase 유전자의 위치는 제한효소 KpnI에 의해 절단되는 약 3kb 단편에 존재하였다. 표시교환 변이법에 의해 야생균주 R. meliloti TAL1372로부터 cellulase 무생산 변이체를 얻어 근류형성 정도를 실험한 결과 CM-cellulase유전자가 근류형성에 관련될 것으로 추정되었다.

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한국 전통탈의 조형미를 응용한 아트메이컵 연구 -산대놀이 탈을 중심으로- (The Study on Art Makeup Applying Characteristic Beauty of Korean Traditional Sandaenori Masks)

  • 이화순
    • 한국의류산업학회지
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    • 제7권2호
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    • pp.237-246
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    • 2005
  • In this study, researcher intended to extract the major factors of makeup design from Yangju-beolsandaenori-tal(masks) and Songpa-sandaenori-tal which have been handed down to the present among many kinds of the Korean folk masks, and to apply those factors to the modernization of traditional culture in terms of makeup design. The 17 Sandaenori-tals exhibited at 'The special exhibition of the Korean folk masks' in 1981 by the national folk museum of Korea were selected as the objects of this research. The formational analysis in terms of shape, color and material was conducted. The 5 factors of this analysis are as follows; face and hair, forehead, eye and eyebrows, mouth and nose. The beauty expressed in Sandaenori-tal includes naturalness, eccentricity and good-humor. The human feelings are expressed candidly and simply through naturalness. The eccentricity in Sandaenori-tal overemphasizes the shape of mask unsymmetrically. And it is expressed ghostliy in black, white and red colors. The good-humors in aesthetic viewpoint was expressed in surprised faces and innocent smile. Researcher applies the good humour to the art makeup in strong natural colors and shapes.

전통 탈의 이미지를 활용한 패션문화상품 디자인 개발 (Use of Traditional Mask Images in Design Development for Fashion-Cultural Products)

  • 김선영
    • 복식문화연구
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    • 제19권3호
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    • pp.460-472
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    • 2011
  • This paper developed motifs through the use of images of masks with which the Korean innate consciousness of aesthetics is expressed. The motifs were applied to fashion items. This paper investigated the concept, origin and types of traditional masks through the existing literature. Using the computer graphic programs of Illustrator and Photoshop CS2, three basic motifs were set from the images of the nobleman, Bune of Hahoi Tal and Byeongsan Tal. Each motif was extended into two motifs by changing shape and color. For the basic motif design, this study sought to express contemporary images, suitably for each fashion item, while maintaining the basic shape of the masks and their traditional images. In addition, this study set the concept of the design so that could be accepted by various age groups. For the design of handkerchiefs, a rotating array, involving enlargement, reduction, repetition, and the gradation of motifs, as well as a diagonal symmetric array, and all-over patterns were developed. The T-shirt design created here was divided into a half-sleeve box type, a round neckline sleeveless type, a V-neckline close-fitting sleeveless type, and a V-neckline close-fitting cap sleeve type. For the design of necklaces, OLED or LED, which are considered as a future display type, was used. Additionally, the production of an entertainment styled new atmosphere is proposed.