• Title/Summary/Keyword: TAH

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A study on the development of motor-driven artificial heart and its control (인공심장의 자동제어)

  • 민병구;김희찬;권성일
    • 제어로봇시스템학회:학술대회논문집
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    • 1986.10a
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    • pp.643-647
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    • 1986
  • A new type of motor-driven Total Artificial Heart (TAH) system with rolling-ball mechanism has been developed. To test its performance as a Left Ventricular Assist Device (LVAD), LVAD is controlled to bypass blood for impaired heart triggered by the R-wave in ECG. Results of the test with a Mock Circulation System (MCS) and an animal experiment with a dog are also included. More powerful system using a brushless DC motor has been developed and its control scheme is represented.

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Treatment Outcomes of Epithelial Ovarian Cancers Following Maximum Cytoreduction and Adjuvant Paclitaxel-Carboplatin Chemotherapy: Egyptian NCI Experience

  • Nassar, Hanan Ramadan;Zeeneldin, Ahmed A;Helal, Amany Mohamed;Ismail, Yahia Mahmoud;Elsayed, Abeer Mohamed;Elbassuiony, Mohamed A;Moneer, Manar M
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7237-7242
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    • 2015
  • Background: Epithelial ovarian cancer (EOC) is the commonest malignancy involving the ovaries. Maximum surgical cytoreduction (MCR) followed by adjuvant taxane-platinum chemotherapy are the standard of care treatments. Aims: To study treatment outcomes of EOC patients that were maximally cyto-reduced and received adjuvant paclitaxel-carboplatin (PC) chemotherapy. Materials and Methods: This retrospective cohort study included 174 patients with EOC treated at the Egyptian National Cancer Institute between 2006 and 2010. For inclusion, they should have had undergone MCR with no-gross residual followed by adjuvant PC chemotherapy. MCR was total abdominal hysterectomy/bilateral salpingo-oophorectomy [TAH/BSO] or unilateral salpingo-oophorectomy [USO] plus comprehensive staging. Results: The median age was 50 years. Most patients were married (97.1%), had offspring (92.5%), were postmenopausal (53.4%), presented with abdominal/pelvic pain and swelling (93.7%), had tumors involving both ovaries (45.4%) without extra-ovarian extension i.e. stage I (55.2%) of serous histology (79.9%) and grade II (87.4%). TAH/BSO was performed in 97.7% of cases. A total of 1,014 PC chemotherapy cycles were administered and were generally tolerable with 93.7% completing 6 cycles. Alopecia and numbness were the commonest adverse events. The median follow up period was 42 months. The 2-year rates for disease free survival (DFS) and overall survival (OS) were 70.7% and 94.8%, respectively. The respective 5-year rates were 52.6% and 81.3%. Advanced stage and high-grade were significantly associated with poor DFS and OS (p<0.001). Age >65 years was associated with poor OS (p =0.008). Using Cox-regression, stage was independent predictor of poor DFS and OS. Age was an independent predictor of poor OS.

Effects of Different Sanitizers on the Quality of 'Tah Tasai' Chinese Cabbage (Brassica campestris var. narinosa) Baby Leaves (살균소독제가 다채 어린잎채소(Brassica campestris var. narinosa)의 수확 후 품질에 미치는 영향)

  • Chandra, Dulal;Kim, Ji-Gang
    • Food Science and Preservation
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    • v.18 no.4
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    • pp.429-435
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    • 2011
  • The demand of packaged baby leaves has been increased for its convenient use as fresh-cut produce. This investigation was aimed to explore the effects of different sanitizers on the quality parameters of 'Tah Tasai' Chinese cabbage (Brassica campestris var. narinosa) baby leaves. Thirteen days old baby leaves were harvested and washed in tap water (TW), 100 ppm chlorine solution (Cl), 2 ppm ozonated water ($O_3$), 15 ppm chlorine dioxide solution ($ClO_2$) and washing with 0.2% citric acid solution followed by 50% ethanol spray (CA+Et). The samples were then packaged in 50 ${\mu}m$ polyethylene bags and stored at $5^{\circ}C$ for 10 days. Off-odor of packaged baby leaves was not detected during storage. There was no significant difference in color parameters among the treatments. Samples treated with $O_3$ showed substantially higher electrolyte leakage throughout the storage. This treatment also rendered a higher accumulation of $CO_2$ in the packages. Samples treated with Cl and CA+Et maintained good overall visual quality with higher scores compared to that of $O_3$ and $ClO_2$. Although Cl treatment showed lower number of total aerobic count at the beginning of storage, citric acid in combination with ethanol treatment was more effective until the end of storage. The combined treatment also showed comparatively lower coliform plate count. This result indicates that citric acid wash followed by ethanol spray could be an alternative to chlorine for environment friendly sanitization of baby leaves.

Implementation of a Circuit for the Enhancement of Signal to Noise Ratios of Current Signal in a Artificial Heart (인공심장 전류 신호의 신호대 잡음비 개선을 위한 회로 구현)

  • Choi, J.H.;Lee, J.H.;Choi, W.W.;Ahn, J.M.;Kim, W.E.;Lee, J.J.;Om, K.S.;Choi, J.S.;Park, S.K.;Cho, Y.H.;Kim, H.C.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.277-280
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    • 1996
  • We have developed a ground-isolation circuit in order to reduce the noise of the internal controller system for the total artificial heart(TAH) and ventricular assist device(VAD). Using the ground-isolation technique, we could transmit the analog target signal to other pheriperal device including IBM PC via RS232C and polygraph, with no noise. Experimental results of VAD showed that there was less impulsive noise in current signal which caused in our previous conventional system. Therefore it could be proved that implementation of isolation technique is very effective to improve the signal to noise ratios of analog signal transmission for TAH or VAD.

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A Study on Miniaturization of Digital Controller for both Implantable Total Artificial Heart (TAH) and Ventricular Assist Device (VAD) using PSD302 (PSD302를 이용한 완전 이식형 인공심장 및 심실보조장치 제어용 디지탈 콘트롤러 소형화에 관한 연구)

  • Lee, J.H.;Choi, J.H.;Lee, J.J.;Kim, W.E.;Om, K.S.;Choi, J.S.;Ahn, J.M.;Choi, W.W.;Park, S.K.;Cho, Y.H.;Kim, H.C.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.273-276
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    • 1996
  • In the Total Artificial Heart (TAH) and Ventricular Assist Device (VAD), the size implanting the internal controller into human body is very serious problem. Hence, we need the size reduction of that controller for safe implantation. Using PSD302 chip for microcontroller-based applications, we could decrease the number of components in the digital control board and miniaturize the digital control board. We could replace a ROM, RAM, and a latch with that single chip, so the size of the newly developed board could be half the previous board.

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Resolution in Carrier Profiling Semiconductors by Scanning Spreading Resistance Microscopy and Scanning Frequency Comb Microscopy

  • Hagmann, Mark J.;Mousa, Marwan S.;Yarotski, Dmitry A.
    • Applied Microscopy
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    • v.47 no.3
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    • pp.95-100
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    • 2017
  • High resolution measurements of the carrier profile in semiconductor devices is required as the semiconductor industry progresses from the 10-nm lithography node to 7-nm and beyond. We examine the factors which determine the resolution of the present method of scanning spreading resistance microscopy as well as such factors for the newer method of scanning frequency comb microscopy that is now under development. Also, for the first time, we consider the sensitivity of both methods to the location of heterogeneities in the semiconductor. In addition, mesoscopic effects on these measurements are considered for the first time. Two simple analytical models are extended to study the sensitivity to heterogeneities as well as mesoscopic effects.

FUZZY Gain Tuning of PI Speed Controller Depending on Afterloads In Total Artificially Heart

  • Choi, Jong-Hoon;Choi, Won-Woo;Choi, Jae-Soon;Om, Kyong-Sik;Lee, Jung-Hoon;Min, Byoung-Goo
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.156-160
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    • 1997
  • In this paper, the control scheme is proposed that PI controller parameter used for TAH speed control is adapted by fuzzy logic method using only the motor current waveform. By scheduling PI parameters, minimization of the vibration and the energy consumption and overcoming AoP loads becomes possible. In in vitro tests experimental results show our approach is a good scheme that is adapted to changing afterloads well.

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A Study on the Control of Brushless DC Motor for Total Artificial Heart (인공심장용 브러시리스 직류전동기 제어에 관한 연구)

  • Kwon, S.I.;Lee, S.H.;Kim, J.T.;Kim, H.C.;Min, B.G.
    • Proceedings of the KIEE Conference
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    • 1987.07b
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    • pp.1317-1321
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    • 1987
  • A new type of motor-driven Total Artificial Heart(TAH) system with rolling cylinder mechanism has been developed. Brushless DC motor was chosen as energy converter and controlled by PI controller according to the given velocity profile under the highly time-varying load. Computer simulation was also performed to calculate the optimal gains of PI controller which minimize the input power, one of the most important parameter in artificial heart system.

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Automatic cardiac output control algorithm for total artificial heart by current waveform analysis (전류파형분석에 의한 완전이식 인공심장의 심박출량 자동제어 알고리즘)

  • 최원우;김희찬;민병구
    • 제어로봇시스템학회:학술대회논문집
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    • 1993.10a
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    • pp.383-391
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    • 1993
  • In this paper, a new automatic cardiac output control algorithm without any pressure sensors for the motor-driven electromechanical total artificial heart(TAH) was developed using motor current information. In the previous studies, many transducers were utilized to obtain informations of hemodynamic states for the automatic cardiac output control. But. such automatic control with sensors has some problems. To solve these problems, I proposed a new "sensorless" automatic cardiac output control algorithm providing the adequate cardiac output to the time-varying physiological demand without right atrial collapse. In-vitro tests were performed to evaluate the performance of a new algorithm and it satisfied the basic three requirements on the pump output response through the mock circulation tests.

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