• Asian Pacific Journal of Cancer Prevention
• /
• 제15권11호
• /
• pp.4487-4491
• /
• 2014

Objective: To explore the clinical manifestations and imaging characteristics of gliomatosis cerebri to raise the awareness and improve its diagnostic accuracy for patients. Materials and Methods: Clinical data, imaging characteristics and pathological examination of 12 patients with GC from Jan., 2008 to Jan., 2012 were analyzed retrospectively. Results: Patients with GC were clinically manifested with headache, vomiting, repeated seizures, fatigue and unstable walking, most of whom had more than 2 lesions involving in parietal lobe, followed by temporal lobe, frontal lobe, periventricular white matter and corpus callosum. Magnetic resonance imaging (MRI) showed diffuse distribution, T1-weighted images (T1WI) with equal and low signals and T2-weighted images (T2WI) with bilateral symmetrical high diffuse signals. There was no reinforcement by enhancement scanning and signals were different in diffusion-weighted images (DWI). The higher the tumor staging, the stronger the signals. Pathological examination showed neuroastrocytoma in which tumor tissues were manifested by infiltrative growth in blood vessels and around neurons. Conclusions: In clinical diagnosis of GC, much attention should be paid to the diffuse distribution of imaging characteristics, incomplete matching between clinical and imaging characteristics and confirmation by combining with histopathological examination.

• Journal of Korean Neurosurgical Society
• /
• 제46권2호
• /
• pp.161-164
• /
• 2009

Plasma cell granuloma is a tumor-like disease characterized by non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. This disease occurs most frequently in the lung and upper respiratory tract, while the involvement of the central nervous system is very rare. A 44-year-old female patient presented with nausea and progressive visual disturbance. Brain magnetic resonance imaging (MRI) revealed the mass along the right tentorium with low signal intensity in the T2 weighted image (T2WI) and fluid-attenuated inversion recovery (FLAIR) sequence, and an isosignal intensity in T1 weighted image (T1WI), the latter of which was enhanced after administration of gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA). The thickest portion of the tentorium was partially excised via the combined suboccipital and infratentorial approach. The histopathological examination indicated a diagnosis of plasma cell granuloma. Postoperative steroid therapy was administered for remnant tumor control. Although a follow up MRI scan taken 20 months after the operation showed a slight decrease in tumor size, the lesion had extended to the falx and left frontal convexity along with parenchymal edema at 32 months after the operation and the clinical status was aggravated. The mass was removed from the left frontal convexity. Radiation therapy was given, together with steroid administration.

• Journal of Korean Neurosurgical Society
• /
• 제54권6호
• /
• pp.467-476
• /
• 2013

Objective : This study aimed to evaluate the hypotheses that administration routes [intra-arterial (IA) vs. intravenous (IV)] affect the early stage migration of transplanted human bone marrow-derived mesenchymal stem cells (hBM-MSCs) in acute brain infarction. Methods : Male Sprague-Dawley rats (n=40) were subjected to photothrombotic infarction. Three days after photothrombotic infarction, rats were randomly allocated to one of four experimental groups [IA group : n=12, IV group : n=12, superparamagnetic iron oxide (SPIO) group : n=8, control group : n=8]. All groups were subdivided into 1, 6, 24, and 48 hours groups according to time point of sacrifice. Magnetic resonance imaging (MRI) consisting of T2 weighted image (T2WI), $T2^*$ weighted image ($T2^*WI$), susceptibility weighted image (SWI), and diffusion weighted image of rat brain were obtained prior to and at 1, 6, 24, and 48 hours post-implantation. After final MRI, rats were sacrificed and grafted cells were analyzed in brain and lung specimen using Prussian blue and immunohistochemical staining. Results : Grafted cells appeared as dark signal intensity regions at the peri-lesional zone. In IA group, dark signals in peri-lesional zone were more prominent compared with IV group. SWI showed largest dark signal followed by $T2^*WI$ and T2WI in both IA and IV groups. On Prussian blue staining, IA administration showed substantially increased migration and a large number of transplanted hBM-MSCs in the target brain than IV administration. The Prussian blue-positive cells were not detected in SPIO and control groups. Conclusion : In a rat photothrombotic model of ischemic stroke, selective IA administration of human mesenchymal stem cells is more effective than IV administration. MRI and histological analyses revealed the time course of cell migration, and the numbers and distribution of hBM-MSCs delivered into the brain.

• 한국식품위생안전성학회지
• /
• 제23권4호
• /
• pp.330-337
• /
• 2008

베타리치 당근을 HCA 농도별 침지시간별로 각각 세척한 후 PE bag에 포장하여 $8^{\circ}C$에서 12일간 저장하여 미생물분석, 경도, 표면색, 백화지수 및 관능적 품질변화를 조사하였다. 총균수는 침지시간을 3분으로 한 처리구 T-II는 $4.37{\pm}0.19\;\log\;CFU/g$, T-III는 $4.27{\pm}0.13\;\log\;CFU/g$로 저장초기의 대조구에서 보다 적게 나타났다. 대장균군의 경우 저장일수 8일차의 처리구 T-II와 T-III는 대조구보다 적게 검출되었으며, 모든 처리구에서 E. coli는 검출되지 않았다. 3분 침지한 처리구가 1분 침지한 처리구보다 저장 12일 차에서 경도의 감소폭이 적었으며, T-I T-II, T-III로 갈수록 감소폭이 줄어들었다. 저장기간 중 모든 처리구의 L값은 감소하였고 a와 b값은 증가하였다. WI는 저장기간 중 증가하였으며, HCA 처리농도가 증가할수록 증가폭은 적었다. 저장 8일차의 관능적 품질평가 결과, 무처리구와 HCA 처리구의 이취평가는 유의적으로 높게 나타났다(p<0.05). 이상의 결과를 종합해 볼 때 유통기한 연장을 위하여 당근 세척에 HCA을 50 ppm 이상 사용하는 것이 안전성 및 품질 향상에 효과적인 것으로 나타났다.

• Journal of Korean Neurosurgical Society
• /
• 제57권4호
• /
• pp.235-241
• /
• 2015

Objective : Magnetic resonance imaging (MRI) of chronic subdural hematoma (CSDH) detects various patterns, which can be attributed to many factors. The purpose of this study was to measure the level of interleukin-6 (IL-6), interleukin-8 (IL-8), and highly specific protein [beta-trace protein (${\beta}TP$)] for cerebrospinal fluid (CSF) in CSDHs, and correlate the levels of these markers with the MRI findings. Methods : Thirty one patients, treated surgically for CSDH, were divided on the basis of MRI findings into hyperintense and non-hyperintense groups. The concentrations of IL-6, IL-8, and ${\beta}TP$ in the subdural fluid and serum were measured. The ${\beta}TP$ was considered to indicate an admixture of CSF to the subdural fluid if ${\beta}TP$ in the subdural fluid $({\beta}TP_{SF})/{\beta}TP$ in the serum $({\beta}TP_{SER})>2$. Results : The mean concentrations of IL-6 and IL-8 of the hyperintense group (n=17) of T1-WI MRI were $3975.1{\pm}1040.8pg/mL$ and $6873.2{\pm}6365.4pg/mL$, whereas them of the non-hyperintense group (n=14) were $2173.5{\pm}1042.1pg/mL$ and $2851.2{\pm}6267.5pg/mL$ (p<0.001 and p=0.004). The mean concentrations of ${\beta}TP_{SF}$ and the ratio of ${\beta}TP_{SF}/{\beta}TP_{SER}$ of the hyperintense group (n=13) of T2-WI MRI were $7.3{\pm}2.9mg/L$ and $12.6{\pm}5.4$, whereas them of the non-hyperintense group (n=18) were $4.3{\pm}2.3mg/L$ and $7.5{\pm}3.9$ (p=0.011 and p=0.011). Conclusion : The hyperintense group on T1-WI MRI of CSDHs exhibited higher concentrations of IL-6 and IL-8 than non-hyperintense group. And, the hyperintese group on T2-WI MRI exhibited higher concentrations of ${\beta}TP_{SF}$ and the ratio of ${\beta}TP_{SF}/{\beta}TP_{SER}$ than non-hyperintense group. These findings appear to be associated with rebleeding and CSF admixture in the CSDHs.

• 대한핵의학회지
• /
• 제39권4호
• /
• pp.263-265
• /
• 2005

A 25 years old male patient with Hodgkin's disease, considered as complete remission, underwent $^{18}F$-FDG whole body PET/CT. $^{18}F$-FDG whule body PET/CT showed unexpected hypermetabolic nodule in left quadratus femoris muscle suggesting local recurrence. Subsequent MRI also revealed well-enhancing nodular lesion with intermediate and high signal intensity on T1WI and T2WI, respectively. The lesion was confirmed as nodular fasciitis by pathologic examination of the excited specimen.

• 한국정보통신학회논문지
• /
• 제21권4호
• /
• pp.679-687
• /
• 2017

본 논문에서는 DGS (Defected Ground Structure)를 적용한 WLAN/WiMAX 시스템에 적용 가능한 모노폴 안테나를 제안하였다. 제안된 안테나는 마이크로스트립 급전을 바탕으로 두 개의 선로와 DGS를 갖도록 구성하여 삼중대역 특성을 갖도록 설계하였다. 두 개의 선로 그리고 세 개의 슬릿의 위치 및 길이와 DGS 위치와 길이를 적절한 조정하여 본 논문에서 요구되는 특성을 얻기 위한 최적화 수치를 얻었다. 제안된 안테나는 $34mm(W_1){\times}34mm(L_1){\times}1.6mm(t)$의 비유전율 4.4인 FR-4 유전체 기판 위에 $17.0mm(W_6){\times}30.75mm(L_3+L_4+L_9)$의 크기로 제작되었다. 제작 및 측정결과로부터 -10 dB 임피던스 대역폭을 기준으로 360 MHz (2.335~2.695 GHz), 645 MHz (3.37~4.015 GHz) 그리고 1,770 MHz (5.14~6.91 GHz)의 대역폭을 얻었다. 또한 제안된 안테나는 요구되는 삼중대역에서 측정된 이득과 방사패턴의 얻었다.

• 대한방사선기술학회지:방사선기술과학
• /
• 제23권1호
• /
• pp.39-47
• /
• 2000

In this study, we showed a comparison and analysis making use of DWI(diffusion weighted image) using early diagnosis of cerebral Infarction and with the classified T2 weighted image, FLAIR images signal intensity for brain infarction period. period of cerebral infarction after the condition of a disease by ischemic stroke. To compare 3 types of image, we performed polynomial warping and affined transform for image matching. Using proposed algorithm, calculated signal intensity difference between T2WI, DWI, FLAIR and DWI. The quantification values between hand made and calculated data are almost the same. We quantified the each period and performed pseudo color mapping by comparing signal intensity each other according to previously obtained hand made data, and compared the result of this paper according to obtained quantified data to that of doctors decision. The examined mean and standard deviation for each brain infarction stage are as follows ; the means and standard deviations of signal intensity difference between DWI and T2WI for each period are $197.7{\pm}6.9$ in hyperacute, $110.2{\pm}5.4$ in acute, and $67.8{\pm}7.2$ in subacute. And the means and standard deviations of signal intensity difference between DWI and FLAIR for each period are $199.8{\pm}7.5$ in hyperacute, $115.3{\pm}8.0$ in acute, and $70.9{\pm}5.8$ in subacute. We can quantificate and decide cerebral infarction period objectively. According to this study, DWI is very exact for early diagnosis. We classified the period of infarction occurrence to analyze the region of disease and normal region in DW, T2WI, FLAIR images.

• 한국인터넷방송통신학회논문지
• /
• 제19권1호
• /
• pp.15-20
• /
• 2019

사물인터넷이 발전으로 초소형 통신장치를 설치한 의류, 스포츠 장비, 웨어러블 디바이스 등을 활용한 다양한 장거리를 요하는 서비스의 개발로 인하여 기존에 IoT를 위하여 대표적으로 활용되던 Wi-Fi 와 Zigbee와 같은 근거리 네트워크에서의 거리의 한계가 느껴지면서 장거리 통신 기술인 LPWAN에 대한 연구가 진행이 되었다. 본 논문에서는 LPWAN 기술중 비 대역망 기술인 LoRa 기술의 세부부분들에 대하여 소개하고, 국내와 국외에서 활용되고 있는 다양한 활용사례를 조사 및 분석하여 LoRa를 사용하는 실내 및 근거리 게이트웨이를 통한 통신방식에서 장거리 통신방식으로 연구가 진행이 되고 있는 것을 확인 할 수 있었다.

• Journal of Korean Neurosurgical Society
• /
• 제29권7호
• /
• pp.899-903
• /
• 2000

Objective : Object : A 7-year retrospective clinical and MRI study was reviewed to evaluate the characteristics of pineal cyst. We evaluated results of clinical and radiologic change of pineal cyst during follow up period. Patients and Methods : From 1992 to 1999, 50 patients with pineal cyst were visited for evaluation. Follow up clinical information was obtained from patients or clinical record through phone conversation. also radiologic findi-ngs of pineal cyst in mid-sagittal MRI were reviewed in detail. Results : Pineal cysts were usually asymptomatic and detected incidentally during evaluation of other diseases. Sagittal MRI is the most useful diagnostic test. The radiologic findings of pineal cyst were isointensity on T1WI comared to CSF and slightly high signal intensity on T2WI. Cyst wall was variably enhanced on Gad-enhanced T1WI. The average size of cyst was $13.9{\times}13.0mm$. The pineal cyst was classified into five groups according to previous report. Long term behavior of these lesions are not apparent, but in our study they showed no specific changes in clinical and radiological aspects during 25 months. Conclusion : Although long-term follow up results are needed, the pineal cyst are considered as normal variants. In our 25 months follow up results, there was no rapid change of cyst both clinically and radiologically. Therefore, frequent radiologic evaluation seems unnecessary except type III pineal cyst.