• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1397-1403
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• 2004

By recently study, GM (Gamipaemo-tang) treatment have worked well on the allergic asthma. The purpose of this study was effect of GM extract on helper T cell, major regulator of immune system. Splenic cells from 8-week BALB/c mice were cultured in GM containing media without activation for 48 hours. The MTS assay and flow cytometry study revealed that lymphocyte treated with GM were not effective on CD4+ T cells. Subsequently CD4+ T cells were isolated and cultured in GM containing media. Either GM were not effective on CD4+ T cell without APCs. By FACS scan analysis, the expression of INF-γ, IL-4 were down-regulated in the condition skewed Th1 and Th2 cells respectively, Using ELISA analysis, the expression of INF-γ is up-regulated and IL-4 is down-regulated in the condition skewed Th1, Th2 cells respectively. With RT-PCR analysis, the expression of mRNA for INF-γ is down-regulated and IL-4 is down-regulated in the condition skewed Th1 and Th2 cells respectively. The result suggests that GM inhibited the differetiation of Th2 cells significantly and indicates GM could enhance anti-allergic immune system.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.26-32
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• 2014

Purpose: As PET-MRI which has excellent soft tissue contrast is developed as integration system, many researches about clinical application are being conducted by comparing with existing display equipments. Because PET-MRI is actively used for head and neck cancer diagnosis in our hospital, lymph node metastasis before the patient's surgery was diagnosed and clinical usefulness of head and neck cancer PET-MRI scan was evaluated using pathological opinions and idiopathy surrounding tissue metastasis evaluation method. Materials and Methods: Targeting 100 head and neck cancer patients in SNUH from January to August in 2013. $^{18}F-FDG$ (5.18 MBq/kg) was intravenous injected and after 60 min of rest, torso (body TIM coil, Vibe-Dixon) and dedication (head-neck TIM coil, UTE, Dotarem injection) scans were conducted using $Bio-graph^{TM}$ mMR 3T (SIEMENS, Munich). Data were reorganized using iterative reconstruction and lymph node metastasis was read with Syngo.Via workstation. Subsequently, pathological observations and diagnosis before-and-after surgery were examined with integrated medical information system (EMR, best-care) in SNUH. Patient's diagnostic information was entered in each category of $2{\times}2$ decision matrix and was classified into true positive (TP), true negative (TN), false positive (FP) and false negative (FN). Based on these classified test results, sensitivity, specificity, accuracy, false negative and false positive rate were calculated. Results: In PET-MRI scan results of head and neck cancer patients, positive and negative cases of lymph node metastasis were 49 and 51 cases respectively and positive and negative lymph node metastasis through before-and-after surgery pathological results were 46 and 54 cases respectively. In both tests, TP which received positive lymph node metastasis were analyzed as 34 cases, FP which received positive lymph node metastasis in PET-MRI scan but received negative lymph node metastasis in pathological test were 4 cases, FN which received negative lymph node metastasis but received positive lymph node metastasis in pathological test was 1 case, and TN which received negative lymph node metastasis in both two tests were 50 cases. Based on these data, sensitivity in PET-MRI scan of head and neck cancer patient was identified to be 97.8%, specificity was 92.5%, accuracy was 95%, FN rate was 2.1% and FP rate was 7.00% respectively. Conclusion: PET-MRI which can apply the acquired functional information using high tissue contrast and various sequences was considered to be useful in determining the weapons before-and-after surgery in head and neck cancer diagnosis or in the evaluation of recurrence and remote detection of metastasis and uncertain idiopathy cervical lymph node metastasis. Additionally, clinical usefulness of PET-MRI through pathological test and integrated diagnosis and follow-up scan was considered to be sufficient as a standard diagnosis scan of head and neck cancer, and additional researches about the development of optimum MR sequence and clinical application are required.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.36T no.1
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• pp.51-57
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• 1999

This thesis is written about the Wired Logic Type Unit in developing equipment that the load is driven, that the interface unit connect with 1 Scan time to PO30 of operated PLC output contact with that a sensing signal of Temperature Sensor RSD Pt $100\Omega$ let generate the relay output of temperature controller and input the PLC. The PLC Test Kit in country that the PLC to be programmed at the PLC education place is able to drive the load, is done to do a education of PLC on status that interface process between PLC and load are disregarded. As Developing Kit for supplement this point, when the relay output of temperature controller to use Pt 100 of temperature sensor as mentioned on the former among every kinds of sensor feed back to the input of the PLC, as the equipment to act with real time system that the output contact of PLC operated to insert the WLTIJ among PC, PLC and the load, it can understand and see very easy the main principle of PLC use. The structure of WLTU to be a interface unit of load separated as to the point of contact and noncontact, sensor, indicating lamp and A contact and B contact that is belong to driving part, and a motor is belong to loading part.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.674-682
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• 2009

The purpose of this study was to investigate the effect of aquatic gait training on plantar foot pressure, foot kinesiology and gait speed in right hemiplegic patients. The subject were 20 stroke patients who elapsed from 12 month to 24 month after stroke(aquatic gait training group(n=10), land gait training group(n=10)). This study measured plantar foot pressure, toe out angle, subtalar joint angle, gait speed from data of gate on 2m long measuring apparatus for RS-scan system(RS scan Ltd. German). This experiment performed in twice, before and after the aquatic gait training and land gait training. Collected data were statistically analyzed by SPSS Ver. 12.0 using descriptive statistics, paired t-test. Aquatic gait training group had more variety pressure area on their foot such as T1(Toe 1), HM(Heel medial), and HL(Heel lateral). But motion of subtalar joint flexibility and toe out angle decreased considerably and gate speed also increased. According to the result, aquatic gait training is considered as more effective way in foot stability and normal gait pattern than land gait training.

• The Journal of Advanced Prosthodontics
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• v.5 no.3
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• pp.256-261
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• 2013

PURPOSE. Occlusal splints are commonly used to prevent tooth wear caused by bruxism. However, the effects of splints on occlusion are still unclear. Although it is rarely alluded in literature, splints can provoke severe occlusal alterations and other complications. This study was aimed to identify differences in the responses of individuals with bruxism and healthy individuals to a full-arch maxillary stabilization splint in terms of occlusal changes. MATERIALS AND METHODS. Occlusal contacts in 20 (5 male, 15 female) bruxism patients and 20 (5 male, 15 female) controls with normal occlusion were evaluated before and after occlusal splint therapy. T-Scan III, a computerized occlusal analysis system, was used to simultaneously measure occlusion and disclusion times as well as left-right and anterior-posterior contact distributions before splint therapy and 3 months after therapy. Wilcoxon and Mann-Whitney U tests were used for statistical analyses (${\alpha}$=.05). RESULTS. No differences were found in the posterior contact of bruxism patients before and after stabilization splint treatment. However, differences in posterior contact were observed between bruxists and normal individuals prior to treatment, and this difference disappeared following treatment. CONCLUSION. The results of this study showed the use of a stabilization splint may not have an effect on occlusion. However, the area of posterior occlusal contact among bruxists was found to be greater than that of normal individuals. According to this study, the clinical use of splints may be harmless.

• Journal of Korea Spatial Information System Society
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• v.11 no.1
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• pp.127-136
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• 2009

This paper proposes an on-line mining algorithm of moving trajectory patterns in RFID data streams considering changing characteristics over time and constraints of single-pass data scan. Since RFID, sensor, and mobile network technology have been rapidly developed, many researchers have been recently focused on the study of real-time data gathering from real-world and mining the useful patterns from them. Previous researches for sequential patterns or moving trajectory patterns based on stream data have an extremely time-consum ing problem because of multi-pass database scan and tree traversal, and they also did not consider the time-changing characteristics of stream data. The proposed method preserves the sequential strength of 2-lengths frequent patterns in binary relationship table using the time-evolving graph to exactly reflect changes of RFID data stream from time to time. In addition, in order to solve the problem of the repetitive data scans, the proposed algorithm infers candidate k-lengths moving trajectory patterns beforehand at a time point t, and then extracts the patterns after screening the candidate patterns by only one-pass at a time point t+1. Through the experiment, the proposed method shows the superior performance in respect of time and space complexity than the Apriori-like method according as the reduction ratio of candidate sets is about 7 percent.

• Physical Therapy Korea
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• v.16 no.4
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• pp.31-36
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• 2009

Hemiplegia-induced immobilizatoin and reduction of mechanical loading in chronic stroke limbs are common cause of disuse osteoporosis. The purpose of this study was to investigate the effects of asymmetrical weight bearing on the loss of bone mineral in the individual with chronic stroke. Sixteen hemiplegic patients with strokes were evaluated. The measurements of bone mineral density (BMD) were evaluated with the quantitative ultrasound system on the calcaneus region of the paretic and non-paretic side. Plantar pressure was measured using the Mat-Scan system. The paretic side showed significantly smaller values in the T-score of BMD, and peak value of plantar pressure, which included forefoot, midfoot, and hindfoot, than the non-paretic side (p<.05). Results from the pearson correlation analysis showed statistically significant correlation between the BMD difference and the peak-pressure difference of midfoot pressure (p<.05). This finding indicated that BMD loss depended on decrease of body weight born on the paretic leg.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.39 no.2
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• pp.90-94
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• 2002

This paper is related to remote meter-reading using magnetic sensor. Scan system which is developed recently has week point of temperature, humidity, dust, oscillation To solve these problems, this study used magnetic action to measure the consumption of gas. Gas consumption was detected by interaction of a permanent magnet and hall element. Permanent magnet was pasted on rolling change-gear in normal gas meter and hall sensor was pasted on the external wall of normal gas meter. This experiment proved high accuracy and wasn't influenced by temperature, humidity, oscillation and dust

• Journal of the Korean Society of Radiology
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• v.12 no.2
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• pp.193-199
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• 2018

In this research, 15 patients were diagnosed with 1.5T and 3.0T MRI instruments (Philips, Medical System, Achieva) to minize Ferromagnetic artifact and find the optimized Tesla. Based on the theory that the 3.0T, when compared to 1.5T, show relatively high signal-to-ratio(SNR), Scan time can be shortened or adjust the image resolution. However, when using the 3.0T MRI instruments, various artifact due to the magnetic field difference can degrade the diagnostic information. For the analysis condition, area of interest is set at the background of the T1, T2 sagittal image followed by evaluation of L3, L4, L5 SNR, length of 3 parts with Ferromagnetic artifact, and Histogram. The validity evaluation was performed by using the independent t test. As a result, for the SNR evaluation, mere difference in value was observed for L3 between 1.5T and 3.0T, while big differences were observed for both L4, and L5(p<0.05). Shorter length was observed for the 1.5T when observing 3 parts with Ferromagnetic artifact, thus we can conclude that 3.0T can provide more information on about peripheral tissue diagnostic information(p<0.05). Finally, 1.5T showed higher counts values for the Histogram evaluation(p<0.05). As a result, when we have compared the 1.5T and 3.0T with SNR, length of Ferromagnetic artifact, Histogram, we believe that using a Low Tesla for Spine MRI test can achieve the optimal image information for patients with disk operation like PLIF, etc. in the past.

• Physical Therapy Korea
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• v.15 no.4
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• pp.59-63
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• 2008

Pressure sores are painful and needless complications of critical illness. and manifest as a localized area of ischemic necrosis of tissue caused by pressure. This study analyzed the bed-backrest elevation system combined with hip and knee flexion for lower extremity lower pressure reduction. Eight healthy adults aged 21 to 26 years were recruited. The Body Pressure Measurement Mat of the TekScan system was used to measure the location and magnitude of the peak pressures on the body bed interface. The SPSS statistical package was used to analyze the significance of differences between the general bed-backrest elevation system and the bed-backrest elevation system combined with hip and knee flexion using the paired t-test. The result showed that the body-pressure of the lower extremity was more significantly reduced for the bed-backrest elevation system combined with hip and knee flexion ($26.6{\pm}4.3$ mmHg) than a general bed-backrest elevation system ($37.3{\pm}5.2$ mmHg) (p<.05).